-
公开(公告)号:US20200265969A1
公开(公告)日:2020-08-20
申请号:US16347369
申请日:2017-11-03
Inventor: Suck Hyun Lee , O Pil Kwon , Myung Jo Jung , Tae Ja Kim
IPC: H01B1/12 , H05K9/00 , C23C18/16 , C23C18/40 , H01M8/0206 , H01M8/0221 , H01M8/0228 , C09D11/52
Abstract: The present disclosure relates to an oxidation-resistant and/or corrosion-resistant hybrid structure including a metal layer (thin film layer) coated on the exterior of a conductive polymer structure, and a preparation method for the hybrid structure.
-
公开(公告)号:US20200261325A1
公开(公告)日:2020-08-20
申请号:US16648087
申请日:2018-09-17
Inventor: Chul Ho KIM
Abstract: The present invention is to provide a composition for skin soothing, which is safe from a risk of side effects, and relates to a composition for skin soothing containing a liquid-phase plasma. The liquid-phase plasma of the present invention is obtained by applying plasma as pure energy to a liquid-phase material, and can be used in the skin sensitive to a chemical material without a risk of side effects. Furthermore, the liquid-phase plasma has remarkable effects on the prevention or treatment of dermatitis or photo-aging due to ultraviolet light, and thus is expected to be greatly used in beauty care and mechanical fields.
-
公开(公告)号:US10696722B2
公开(公告)日:2020-06-30
申请号:US16323839
申请日:2017-08-10
Inventor: Yong Sung Kim , Keunok Jung , Ji Hee Ha , Dong Ki Choi , Hye Ji Choi , Ye Jin Kim
Abstract: The present invention relates to a heterodimeric Fc-fused protein comprising a first Fc region and a second Fc region of an immunoglobulin Fc pair and a physiologically active protein composed of two or more different subunits, wherein one or more subunits of the physiologically active protein are linked separately to one or more ends of the N-terminus or C-terminus of the first Fc region and/or the second Fc region, and CH3 domains of the first Fc region and the second Fc region are mutated so as to promote the heterodimeric Fc formation. Moreover, the present invention relates to a pharmaceutical composition comprising the heterodimeric Fc-fused protein. The heterodimeric Fc-fused protein according to the present invention has an advantage in that it can retain the activity of a naturally occurring physiologically active protein whose two or more different subunits exhibit physiological activity by forming a protein complex, because the physiologically active protein can be linked to an immunoglobulin heterodimeric Fc such that the naturally occurring form and structure of the fused protein thereof can be maintained. When the heterodimeric Fc-fused protein according to the present invention is used, there is an advantage in that the in vivo half-life of the physiologically active protein contained in the heterodimeric Fc-fused protein can be significantly increased due to the Fc-mediated long half-life such that various physiological activities thereof in vivo can be long-lasting.
-
公开(公告)号:US10675316B2
公开(公告)日:2020-06-09
申请号:US16066986
申请日:2016-12-14
Inventor: Sung Moon Oh , Ga Hui Oh , Young-Joon Park , Minsun Chang
IPC: A61K36/25 , A23L33/105 , A61P5/24
Abstract: Provided is a composition for preventing and treating a menopausal disorder containing extracts of Dendropanax morbifera LEV. as an active ingredient. Specifically, the extracts of Dendropanax morbifera LEV. exhibit a significant ER agonist activity within a cell, and exhibit a very potent ER agonist (full agonist) activity with an EC50 value of about 100 μg/ml. Thus, the extracts of Dendropanax morbifera LEV. comprising a high content of plant metabolites similar to estrogen can be useful as hormone replacement therapy capable of improving various symptoms derived from a deficiency of estrogen in menopausal women.
-
公开(公告)号:US10647316B2
公开(公告)日:2020-05-12
申请号:US15971500
申请日:2018-05-04
Applicant: HYUNDAI MOTOR COMPANY , KIA MOTORS CORPORATION , AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
Inventor: Hoon Lee , Hyung Sun Jang , Uk Il Yang , Ji Eun Won , Seul Ki Han , Bo Young Yun , Bong Sob Song , Sung Woo Lee , Sang Won Lee
IPC: B60W30/095 , B60W40/09 , G01S13/931 , G06N20/00 , G01S13/72 , G01S15/931 , G01S17/931
Abstract: An apparatus and a method are capable of accurately deciding a maneuver of a surrounding vehicle. The apparatus includes a first surrounding vehicle information detector configured to obtain first surrounding vehicle information for a surrounding vehicle of a vehicle by using a front radar device. The apparatus further includes a second surrounding vehicle information detector configured to obtain second surrounding vehicle information for the surrounding vehicle by using a corner radar device. The apparatus also includes a processor configured to decide a motion of the surrounding vehicle by using the first surrounding vehicle information and the second surrounding vehicle information. The processor is also configured to decide a maneuver of the surrounding vehicle by using maneuver decision logic derived by a mechanical training technique. The processor is further configured to decide a final maneuver of the surrounding vehicle by using the two decision results.
-
76.
公开(公告)号:US20200118441A1
公开(公告)日:2020-04-16
申请号:US16215113
申请日:2018-12-10
Applicant: HYUNDAI MOTOR COMPANY , KIA MOTORS CORPORATION , AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
Inventor: Seul Ki HAN , Su Min JO , Hoon LEE , Sang Won LEE , Sung Woo LEE , Jong Gwan LEE , Bong Sob SONG
Abstract: A close cut-in vehicle identification apparatus includes an information generator configured to generate sensor fusion information, estimated vehicle state information, and risk determination information based on surrounding vehicle information upon receiving the surrounding vehicle information, a feature combination generator configured to extract a plurality of features based on the sensor fusion information, the estimated vehicle state information, and the risk determination information and to combine the extracted features to generate a plurality of feature combinations, a classification learner configured to classify and learn the plurality of feature combinations depending on a weight factor, and a vehicle intention determination device configured to determine intention of a surrounding vehicle based on a classification learning result value to select an optimum feature combination corresponding to identification of the close cut-in vehicle and configured to determine a situation of the close cut-in vehicle based on the selected optimum feature combination.
-
77.
公开(公告)号:US10549314B2
公开(公告)日:2020-02-04
申请号:US15876039
申请日:2018-01-19
Inventor: Jae Ho Kim , Hyo Sop Kim
IPC: B05D3/12 , B81C1/00 , B05D7/02 , C09D1/00 , C09D125/06
Abstract: Disclosed is a coating method using particle alignment, including preparing a cohesive polymer substrate having a smooth surface; and coating the smooth surface of the cohesive polymer substrate with a plurality of particles while forming recesses respectively corresponding to the particles on the smooth surface of the cohesive polymer substrate by pressing the particles to the cohesive polymer substrate, so that binding properties between the particles and the cohesive polymer substrate are enhanced.
-
公开(公告)号:US10483652B2
公开(公告)日:2019-11-19
申请号:US15496555
申请日:2017-04-25
Inventor: Ikmo Park , Tran Huy Hung
Abstract: A multi-beam antenna array system according to an exemplary embodiment of the present disclosure includes: a grounding surface; a plurality of multi-beam antennas which each includes a dielectric substrate and a radiating part formed on the dielectric substrate so as to radiate electromagnetic waves, and is disposed above the grounding surface so as to be spaced apart from each other; and a feed circuit which is formed on a lower portion of the grounding surface, and supplies electric power to the plurality of multi-beam antennas so that the electromagnetic waves are radiated in different directions from the plurality of multi-beam antennas.
-
公开(公告)号:US10400022B2
公开(公告)日:2019-09-03
申请号:US15560232
申请日:2016-03-23
Inventor: Yong Sung Kim , Ye Jin Kim
IPC: C07K14/705 , A61K9/127 , G01N33/574 , G01N33/68 , C07K19/00 , G01N33/53 , A61K47/50 , A61K38/00
Abstract: A peptide that binds specifically to neuropilin-1 (NRP1) without binding to neuropilin-2 (NRP2) is provided. A fusion protein, a fusion antibody, small-molecule drug, a nanoparticle, or a liposome, which comprises the peptide, and a pharmaceutical composition for treating or preventing cancer or angiogenesis-related diseases, and a composition for diagnosing cancer or angiogenesis-related diseases are provided. A polynucleotide encoding the peptide that binds specifically to NRP1 and a method for screening the peptide that binds specifically to NRP1 are provided. An antibody heavy-chain constant region Fc-fused peptide binding specifically to NRP1 has the property of binding specifically to NRP1, and thus when it is administered in vivo, it accumulates selectively in tumor tissue, and widens the intercellular space between tumor-associated endothelial cells to promote its extravasation and increases its tumor tissue penetration.
-
公开(公告)号:US10397254B2
公开(公告)日:2019-08-27
申请号:US15145870
申请日:2016-05-04
Inventor: Tae Shik Shon , Yong Min Park , Hyung Uk Yoo
Abstract: Provided are a method of monitoring a network driving apparatus provided in a network and a system thereof.The present invention provides a network monitoring method that performs monitoring which does not hinder existing network availability through a means for detouring a path of a packet transferred to a monitoring target apparatus by using one or more servers and clients connected to a network and further, provides extensibility which can be applied to the network using various communication protocols through a protocol converting means that detours the path of the packet after converting the existing protocol into a TCP/IP protocol.
-
-
-
-
-
-
-
-
-