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公开(公告)号：US10609492B2
公开(公告)日：2020-03-31
申请号：US16355570
申请日：2019-03-15
Applicant: EarLens Corporation
Inventor： Jake L. Olsen , David Chazan , Jonathan P. Fay , Micha Rosen , Sunil Puria
Abstract: Embodiments of the present invention provide improved methods and apparatus suitable for use with hearing devices. A vapor deposition process can be used to make a retention structure having a shape profile corresponding to a tissue surface, such as a retention structure having a shape profile corresponding to one or more of an eardrum, the eardrum annulus, or a skin of the ear canal. The retention structure can be resilient and may comprise an anatomically accurate shape profile corresponding to a portion of the ear, such that the resilient retention structure provides mechanical stability for an output transducer assembly placed in the ear for an extended time. The output transducer may couple to the eardrum with direct mechanical coupling or acoustic coupling when retained in the ear canal with the retention structure.
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公开(公告)号：US10589093B2
公开(公告)日：2020-03-17
申请号：US15448501
申请日：2017-03-02
Applicant: Incube Labs, LLC
Inventor： Mir Imran
Abstract: Embodiments of the invention provide apparatus, systems and methods for facilitating introduction of a urinary drainage catheter (UDC) into the urinary tract (UT). One embodiment provides a UDC including electrodes for delivering high frequency current to a patient's pudendal nerves to relax the urinary sphincter (US) before passing the UDC therethrough so as reduce the resistance force on the UDC and discomfort to the patient. The electrodes can comprise at least one pair of bipolar electrodes and may be flexible so as to bend and flex within the urethra. The UDC includes one or more lumens including a drainage lumen and an inflation lumen for inflating an anchoring device on the UDC. The UDC can include a pressure sensor to assess relaxation of the US. The UDC may include a second set of electrodes and irrigation lumen for relaxing the US and flushing the urethra with the UDC in place.
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公开(公告)号：US10542924B2
公开(公告)日：2020-01-28
申请号：US15153314
申请日：2016-05-12
Applicant: InCube Labs, LLC
Inventor： Mir Imran , Ben Tranchina
Abstract: A catheter for measuring pressure in the urinary tract of a patient includes a catheter body having a proximal and distal end. A plurality of lumens is formed in the catheter body, and an adaptor is coupled to the proximal end of the catheter body. The adaptor includes a port for each lumen. A first pressure sensor, typically including a balloon, is fluidically coupled to a first lumen and is configured and positioned to measure pressure in a urethra of the patient. A second pressure sensor, also typically including a balloon, is fluidically coupled to a second lumen and is configured and positioned on the catheter body to measure pressure in a bladder of the patient. An expandable retention member, which may be coupled to a third lumen, is positioned on the catheter body between the first and second expandable pressure sensors so that the catheter body may be retained at a selected location in the urinary tract to properly position the fluid pressure sensors in the bladder and urethra, respectively.
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公开(公告)号：US10516950B2
公开(公告)日：2019-12-24
申请号：US16173869
申请日：2018-10-29
Applicant: EarLens Corporation
Inventor： Rodney C. Perkins , Sunil Puria , Jonathan P. Fay
Abstract: Systems, devices, and methods for communication include an ear canal microphone configured for placement in the ear canal to detect high frequency sound localization cues. An external microphone positioned away from the ear canal can detect low frequency sound, such that feedback can be substantially reduced. The canal microphone and the external microphone are coupled to a transducer, such that the user perceives sound from the external microphone and the canal microphone with high frequency localization cues and decreased feedback. Wireless circuitry can be configured to connect to many devices with a wireless protocol, such that the user can receive and transmit audio signals. A bone conduction sensor can detect near-end speech of the user for transmission with the wireless circuitry in a noisy environment. Noise cancellation of background sounds near the user can be provided.
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公开(公告)号：US10350163B2
公开(公告)日：2019-07-16
申请号：US15466434
申请日：2017-03-22
Applicant: Rani Therapeutics, LLC
Inventor： Mir Imran
Abstract: Embodiments of the invention provide swallowable devices, preparations and methods for delivering drugs and other therapeutic agents within the GI tract. Many embodiments provide a swallowable device for delivering the agents. Particular embodiments provide a swallowable device such as a capsule for delivering drugs into the intestinal wall or other GI lumen. Embodiments also provide various drug preparations that are configured to be contained within the capsule, advanced from the capsule into the intestinal wall and degrade to release the drug into the bloodstream to produce a therapeutic effect. The preparation can be operably coupled to delivery means having a first configuration where the preparation is contained in the capsule and a second configuration where the preparation is advanced out of the capsule into the intestinal wall. Embodiments of the invention are particularly useful for the delivery of drugs which are poorly absorbed, tolerated and/or degraded within the GI tract.
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Patent Agency Ranking
公开(公告)号：US10322167B2
公开(公告)日：2019-06-18
申请号：US15730590
申请日：2017-10-11
Applicant: Rani Therapeutics, LLC
Inventor： Mir Imran
Abstract: Embodiments of the invention provide swallowable devices, preparations and methods for delivering drugs and other therapeutic agents within the GI tract. Many embodiments provide a swallowable device for delivering the agents. Particular embodiments provide a swallowable device such as a capsule for delivering drugs into the intestinal wall or other GI lumen. Embodiments also provide various drug preparations that are configured to be contained within the capsule, advanced from the capsule into the intestinal wall and degrade to release the drug into the bloodstream to produce a therapeutic effect. The preparation can be operably coupled to delivery means having a first configuration where the preparation is contained in the capsule and a second configuration where the preparation is advanced out of the capsule into the intestinal wall. Embodiments of the invention are particularly useful for the delivery of drugs which are poorly absorbed, tolerated and/or degraded within the GI tract.
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公开(公告)号：US10307088B2
公开(公告)日：2019-06-04
申请号：US14794022
申请日：2015-07-08
Inventor： Rinat Esenaliev , Donald S. Prough , Yuriy Petrov , Irene Petrov , George Saade , Gayle L. Olson
IPC: A61B5/1455 , A61B5/145 , A61B5/00 , A61B5/1464 , A61B5/1459
Abstract: Optoacoustic diagnostic systems, devices, and methods are described. A system may comprise a console unit and a handheld probe. The console unit comprises a controller, a processor, a photodiode array, an acoustic processing subsystem, and a cooling subsystem. The probe directs light signals from the photodiode array to patient tissue. The light signals each have different wavelengths selected based on the physiological parameter of interest. The probe further comprises an acoustic transducer that receives acoustic signals generated in response to the directed light signals. The probe may comprise a finger-held working end that can be directed to the skull of a fetus within the uterus during labor. The probe can then accurately determine blood oxygenation of the fetus to determine if a caesarian section is necessary.
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公开(公告)号：US10306381B2
公开(公告)日：2019-05-28
申请号：US15384013
申请日：2016-12-19
Applicant: Earlens Corporation
Inventor： Kulbir Sandhu , Cem Shaquer , Kyu-Hwa Jeong
Abstract: Embodiments of the invention include a method of charging a rechargeable battery, the method comprising the steps of: detecting the presence of a rechargeable hearing aid in a hearing aid recharger; generating a unique random ID in the charger; transmitting the unique random ID to the hearing aid using an extremely low power protocol; demodulating the unique ID in the hearing aid; using the demodulated unique ID in a low power protocol to advertise the hearing aid on a network which includes the charger; associating the hearing aid to the charger when the charger which broadcast the unique ID receives that unique ID from a hearing aid using a wireless protocol; using the wireless protocol to communicate between the associated charging station and hearing aid; radiating power from the charger to the hearing aid; and ending the association when the hearing aid is removed from the charger.
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公开(公告)号：US10286215B2
公开(公告)日：2019-05-14
申请号：US12818434
申请日：2010-06-18
Applicant: Rodney C. Perkins , Sunil Puria , Paul C. Rucker
Inventor： Rodney C. Perkins , Sunil Puria , Paul C. Rucker
Abstract: An output assembly is sized for placement in the middle and inner ear, such that removal of bone can be decreased. The output assembly may comprise at least one photo detector, a demultiplexer and an electrode array sized to pass through an incision in the eardrum. An input transducer assembly is configured to transmit a multiplexed optical signal to the output assembly. The input assembly can be configured to transmit the multiplexed optical signal through the eardrum, such that tissue removal can be decreased and the device can be placed without removal of bone, for example. The multiplexed optical signal may comprise a pulse width modulated signal so as to decrease the effect of non-linearities of the light source and light detector and provide quality sound to the user.
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公开(公告)号：US10285646B1
公开(公告)日：2019-05-14
申请号：US15906375
申请日：2018-02-27
Applicant: CeriBell, Inc.
Inventor： Alexander M. Grant , Jianchun Yi , Bradley G. Bachelder , Raymond Woo , Josef Parvizi , Xingjuan Chao
IPC: A61B5/04 , A61B5/0476 , A61B5/00 , A61B5/0478 , A61B5/0492 , A61B5/042 , A61N1/04 , A61N1/05 , A61N1/36 , A61N1/37 , A61N1/02
Abstract: Systems, devices, and methods are provided to assess connection quality between the electrodes of a bioelectrical signal measurement and/or electrical stimulation device and the tissue, typically skin, of the subject. A test signal is provided to a first electrode, voltage differences between the first electrode and additional electrodes are determined, an impedance of the first electrode is determined based on the voltages differences, and the determined impedance indicates connection quality. This process is typically repeated for all of the electrodes to determine connection quality. The user or subject can be alerted if the connection quality is poor, and the bioelectrical signal that is recorded can be provided with data points indicating connection quality during the signal recording.
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