公开(公告)号：US07410632B2

公开(公告)日：2008-08-12

申请号：US10455016

申请日：2003-06-05

申请人： Robert Lin

发明人： Robert Lin

IPC分类号： C07C51/43

CPC分类号： C07C51/42 ,  C07C51/48 ,  Y02P20/52 ,  Y10S423/14 ,  C07C63/26

摘要： A method for removing impurities from a mother liquor comprising a carboxylic acid, a metal catalyst, impurities by (a) evaporating the mother liquor comprising a carboxylic acid, the metal catalyst, impurities, water and a solvent in a first evaporator zone to produce a vapor stream and a concentrated mother liquor stream; (b) evaporating the concentrated mother liquor stream in a second evaporator zone to form a solvent rich stream and a super concentrated mother liquor stream; (c) separating organic impurities with a water-solvent solution from the super concentrated mother liquor in a solid-liquid separation zone to form an aqueous stream and a second aqueous stream; (d) mixing in a mixing zone water and optionally and extraction solvent with the aqueous stream and second aqueous stream to form an aqueous mixture; and (e) adding an extraction solvent to the aqueous mixture in an extraction zone to form an extract stream and a raffinate stream.

摘要翻译： 一种通过（a）在第一蒸发区中蒸发包含羧酸，金属催化剂，杂质，水和溶剂的母液，从含有羧酸，金属催化剂，杂质的母液中除去杂质的方法，以产生 蒸气流和浓缩母液流; （b）在第二蒸发器区域蒸发浓缩的母液流以形成富溶剂流和超浓缩母液流; （c）将固体 - 液体分离区中的超浓缩母液中的水溶剂溶液分离有机杂质以形成含水物流和第二含水物流; （d）在混合区中将水和任选的萃取溶剂与水流和第二含水流混合以形成含水混合物; 和（e）在提取区中向所述含水混合物中加入提取溶剂以形成提取物流和萃余液流。

公开(公告)号：US20080183014A1

公开(公告)日：2008-07-31

申请号：US12020264

申请日：2008-01-25

申请人： Armin DIEFENBACHER ,  Ulrich Hammon ,  Volker Schliephake ,  Georg Sieder

发明人： Armin DIEFENBACHER ,  Ulrich Hammon ,  Volker Schliephake ,  Georg Sieder

IPC分类号： C07C51/487

CPC分类号： C07C51/44 ,  C07C51/48 ,  C07C57/04

摘要： A process for preparing acrylic acid, in which an acrylic acid-comprising product gas mixture obtained by catalytic gas phase partial oxidation of a C3 precursor of acrylic acid is fractionally condensed in a condensation column provided with internals ascending into itself with side draw removal of crude acrylic acid and with liquid phase draw removal of acrylic acid-comprising acid water, and acrylic acid present in acid water is taken up into an extractant and then removed from the extractant and recycled into the condensation column, or taken up in aqueous metal hydroxide, or sent to further purification of the crude acrylic acid.

摘要翻译： 制备丙烯酸的方法，其中通过丙烯酸C 3/3前体的催化气相部分氧化获得的含丙烯酸的产物气体混合物在具有内部升降的冷凝塔中分级冷凝 用丙烯酸粗抽出去除丙烯酸的酸性水，并将存在于酸性水中的丙烯酸吸收到萃取剂中，然后从萃取剂中除去并再循环到冷凝塔中， 或吸收在金属氢氧化物水溶液中，或者进一步纯化粗丙烯酸。

公开(公告)号：US07319169B2

公开(公告)日：2008-01-15

申请号：US11061019

申请日：2005-02-18

申请人： Seong Pil Kang ,  Seok Hwan Choi ,  Kyoung Su Ha ,  Geon Yong Kim ,  Boo Gon Woo ,  Sang Youn Lee ,  Young Bae Kim ,  Koo Hyun Kang

发明人： Seong Pil Kang ,  Seok Hwan Choi ,  Kyoung Su Ha ,  Geon Yong Kim ,  Boo Gon Woo ,  Sang Youn Lee ,  Young Bae Kim ,  Koo Hyun Kang

IPC分类号： C07C51/42

CPC分类号： C07C51/48 ,  C07C57/04

摘要： The present invention relates to a method for producing (meth)acrylic acid comprising a process of recovering (meth)acrylic acid as an aqueous (meth)acrylic acid from a (meth) acrylic acid-containing gas mixture produced by the catalytic gas phase oxidation of at least one reactant selected from the group consisting of propane, propylene, isobutylene and (meth) acrolein, and a system usable for the method.

摘要翻译： 本发明涉及一种生产（甲基）丙烯酸的方法，包括从由（甲基）丙烯酸气体混合物通过催化气相氧化制备的（甲基）丙烯酸水溶液回收（甲基）丙烯酸的方法 的至少一种选自丙烷，丙烯，异丁烯和（甲基）丙烯醛的反应物，以及可用于该方法的系统。

公开(公告)号：US07282151B2

公开(公告)日：2007-10-16

申请号：US10874419

申请日：2004-06-23

申请人： Kenny Randolph Parker ,  Robert Lin

发明人： Kenny Randolph Parker ,  Robert Lin

IPC分类号： B01D11/04

CPC分类号： C07C51/47 ,  B01D33/073 ,  B01D33/60 ,  B01D33/66 ,  B01J31/4023 ,  C07C51/42 ,  C07C51/48 ,  Y02P20/52 ,  Y02P20/584 ,  C07C63/00 ,  C07C63/06 ,  C07C63/26

摘要： A process is disclosed that relates to the recovery of a metal catalyst from an oxidizer purge stream produced in the synthesis of carboxylic acid, typically terephthalic. More particularly, the process involves recovery of a metal catalyst from an oxidizer purge stream through the use of a pressure filter, the combining of water with a mother liquor to recover the metal catalyst and then subjecting an aqueous mixture so formed to a single stage extraction with an extraction solvent to produce an extract stream comprising organic impurities and a raffinate stream comprising the metal catalyst.

摘要翻译： 公开了一种涉及从合成羧酸（通常为对苯二甲酸）中产生的氧化剂清除流回收金属催化剂的方法。 更具体地说，该方法包括通过使用压滤器从氧化剂吹扫流中回收金属催化剂，将水与母液混合以回收金属催化剂，然后将如此形成的含水混合物进行单段萃取 与提取溶剂一起产生包含有机杂质的萃取物流和包含金属催化剂的萃余液流。

公开(公告)号：US07279598B2

公开(公告)日：2007-10-09

申请号：US10560949

申请日：2004-06-25

申请人： Xiangsheng Meng ,  Paraskevas Tsobanakis ,  Jeffrey Malsam ,  Timothy Abraham

发明人： Xiangsheng Meng ,  Paraskevas Tsobanakis ,  Jeffrey Malsam ,  Timothy Abraham

IPC分类号： C07C51/42

CPC分类号： C07C51/48 ,  C07C59/01 ,  C07C57/04

摘要： Disclosed is a process for separating and recovering 3-hydroxypropionic acid from an aqueous solution comprising 3-hydroxypropionic acid and acrylic acid, comprising counter current extracting the aqueous solution with ethyl acetate extractant. Further disclosed is a process for separating and recovering 3-hydroxypropionic acid and acrylic acid from an aqueous solution comprising 3-hydroxypropionic acid and acrylic acid.

摘要翻译： 公开了一种从含有3-羟基丙酸和丙烯酸的水溶液中分离回收3-羟基丙酸的方法，包括用乙酸乙酯萃取剂萃取水溶液的逆流。 另外公开了从含有3-羟基丙酸和丙烯酸的水溶液中分离回收3-羟基丙酸和丙烯酸的方法。

公开(公告)号：US20070193960A1

公开(公告)日：2007-08-23

申请号：US10590685

申请日：2005-02-18

申请人： Timothy Frank ,  Thomas Thyne ,  Felipe Donate

发明人： Timothy Frank ,  Thomas Thyne ,  Felipe Donate

IPC分类号： B01D37/00

CPC分类号： C07C227/40 ,  C07C29/86 ,  C07C51/48 ,  C07C55/10 ,  C07C59/08 ,  C07C55/14 ,  C07C59/265 ,  C07C53/08 ,  C07C31/225 ,  C07C31/205 ,  C07C31/22 ,  C07C31/26 ,  C07C229/24

摘要： A method for a liquid-liquid extraction of hydrophilic organic compounds from aqueous solutions thereof is described. The method generally includes intermixing a sufficient quantity of a specified glycol ether with the aqueous liquor at a first temperature to form a suspension comprising an aqueous raffinate phase and a glycol ether extract phase; separating the glycol ether extract phase from the aqueous raffinate phase; heating the glycol ether extract phase to a second, higher temperature to form a suspension comprising an aqueous extract phase containing a portion of the hydrophilic organic compound and a glycol ether raffinate phase; and separating this glycol ether raffinate phase from the aqueous extract phase. The selected glycol ether has an inverse solubility in water and the partition ratio, value K, for the hydrophilic organic compound is greater than 0.1. This method is useful for recovering valuable hydrophilic organic acids produced via fermentation or produced or used in various manufacturing processes.

摘要翻译： 描述了从其水溶液中液 - 液萃取亲水性有机化合物的方法。 该方法通常包括在第一温度下将足够量的特定二醇醚与含水液体混合以形成包含残液相和二醇醚萃取相的悬浮液; 从萃余水相中分离出乙二醇醚萃取相; 将乙二醇醚提取相加热至第二较高温度以形成包含含有一部分亲水性有机化合物和二醇醚萃余相的含水萃取相的悬浮液; 并从水相萃取相中分离出该二醇醚萃余相。 所选择的二醇醚在水中具有相反的溶解度，并且亲水性有机化合物的分配比值K大于0.1。 该方法可用于回收通过发酵生产或生产或用于各种制造工艺中的有价值的亲水性有机酸。

公开(公告)号：US07247747B2

公开(公告)日：2007-07-24

申请号：US11175356

申请日：2005-07-07

申请人： Piero Melloni ,  Alberto Cerri ,  Marco Santagostino

发明人： Piero Melloni ,  Alberto Cerri ,  Marco Santagostino

IPC分类号： C07C55/00 ,  C07C55/02

CPC分类号： C07C309/66 ,  C07B2200/07 ,  C07C51/377 ,  C07C51/48 ,  C07C51/56 ,  C07C69/63 ,  C07C227/08 ,  C07C227/32 ,  C07C55/32 ,  C07C229/22

摘要： An inner salt of L-carnitine is prepared by reduction, with a suitable reducing agent, of a compound of formu (I): where X1 and X2, which may be the same or different, are hydroxy, C1-C4 alkoxy, phenoxy, halogen, or X1 and X2, when taken together are an oxygen atom and the resulting compound is a derivative of succinic anhydride; Y is halogen, a mesyloxy or a tosyloxy group, and subsequent treatment with water, then with a base and then with trimethylamine.

摘要翻译： 通过用合适的还原剂还原formu（I）化合物制备左旋肉碱的内盐，其中X 1和X 2可以是 相同或不同，为羟基，C 1 -C 4烷氧基，苯氧基，卤素或X 1和X 2 当一起是氧原子并且所得化合物是琥珀酸酐的衍生物时; Y是卤素，甲磺酰氧基或甲苯磺酰氧基，然后用水处理，然后用碱，然后用三甲胺处理。

公开(公告)号：US20070167649A1

公开(公告)日：2007-07-19

申请号：US11688624

申请日：2007-03-20

申请人： Atsushi ISOTANI

发明人： Atsushi ISOTANI

IPC分类号： C07C51/42

CPC分类号： C07C51/50 ,  C07C51/02 ,  C07C51/412 ,  C07C51/43 ,  C07C51/48 ,  C07C55/14 ,  C07C55/02 ,  C07C55/10 ,  C07C55/20 ,  C07C53/122 ,  C07C53/10 ,  C07C53/124

摘要： A novel method is provided whereby a free organic acid can be produced particularly from an ammonium salt of an organic acid having a high melting point obtainable by bioconversion of a carbon source in the presence of a neutralizing agent, efficiently at a low cost, and the used material for reaction and a byproduct can be recycled for reuse without being disposed. An ammonium salt of organic acid A such as a dicarboxylic acid, a tricarboxylic acid or an amino acid is subjected to reactive crystallization by means of acid B such as a monocarboxylic acid satisfying the following formula (1), to separate free organic acid A in solid form: pKa(A)≦pKa(B)  (1)where pKa(A) and pKa(B) represent ionization indices of organic acid A and acid B, respectively, provided that when they have plural values, they represent the minimum pKa among them. The crystallization mother liquor after precipitating and separating organic acid A is, after separating acid B and then an ammonium salt of acid B, recycled for use in the reactive crystallization step. The ammonium salt of acid B is decomposed into acid B and ammonia, which are recycled for use in the reactive crystallization step and as a neutralizing agent in the bioconversion step, respectively.

摘要翻译： 提供了一种新颖的方法，其中可以有效地以低成本有效地生产游离的有机酸，特别是可以通过在中和剂的存在下通过碳源的生物转化而获得的具有高熔点的有机酸的铵盐， 用于反应的所用材料和副产物可以被再循环以便重新使用而不被处置。 将二羧酸，三羧酸或氨基酸等有机酸铵的铵盐通过酸性B如满足下式（1）的一元羧酸进行反应结晶，从而分离游离有机酸A 固体形式：<？in-line-formula description =“In-line Formulas”end =“lead”？> pKa（A）<= PKA（B）（1）<？in-line-formula description = 其中pKa（A）和pKa（B）分别表示有机酸A和酸B的电离指数，条件是当它们具有多个值时，它们代表其中的最小pKa。 沉淀分离有机酸A后的结晶母液在分离出酸B，然后分离出酸B的铵盐后再循环用于反应结晶步骤。 酸B的铵盐分解成酸B和氨，分别在生物转化步骤中再循环用于反应结晶步骤和中和剂。

公开(公告)号：US20070161816A1

公开(公告)日：2007-07-12

申请号：US11688647

申请日：2007-03-20

申请人： Atsushi ISOTANI

发明人： Atsushi ISOTANI

IPC分类号： C07C61/08

CPC分类号： C07C51/50 ,  C07C51/02 ,  C07C51/412 ,  C07C51/43 ,  C07C51/48 ,  C07C55/14 ,  C07C55/02 ,  C07C55/10 ,  C07C55/20 ,  C07C53/122 ,  C07C53/10 ,  C07C53/124

摘要： A novel method is provided whereby a free organic acid can be produced particularly from an ammonium salt of an organic acid having a high melting point obtainable by bioconversion of a carbon source in the presence of a neutralizing agent, efficiently at a low cost, and the used material for reaction and a byproduct can be recycled for reuse without being disposed. An ammonium salt of organic acid A such as a dicarboxylic acid, a tricarboxylic acid or an amino acid is subjected to reactive crystallization by means of acid B such as a monocarboxylic acid satisfying the following formula (1), to separate free organic acid A in solid form: pKa(A)≦pKa(B)  (1) where pKa(A) and pKa(B) represent ionization indices of organic acid A and acid B, respectively, provided that when they have plural values, they represent the minimum pKa among them. The crystallization mother liquor after precipitating and separating organic acid A is, after separating acid B and then an ammonium salt of acid B, recycled for use in the reactive crystallization step. The ammonium salt of acid B is decomposed into acid B and ammonia, which are recycled for use in the reactive crystallization step and as a neutralizing agent in the bioconversion step, respectively.

摘要翻译： 提供了一种新颖的方法，其中可以有效地以低成本有效地生产游离的有机酸，特别是可以通过在中和剂的存在下通过碳源的生物转化而获得的具有高熔点的有机酸的铵盐， 用于反应的所用材料和副产物可以被再循环以便重新使用而不被处置。 将二羧酸，三羧酸或氨基酸等有机酸铵的铵盐通过酸性B如满足下式（1）的一元羧酸进行反应结晶，从而分离游离有机酸A 固体形式：<？in-line-formula description =“In-line Formulas”end =“lead”？> pKa（A）<= pKa（B）（1）<？in-line-formula description = 其中pKa（A）和pKa（B）分别表示有机酸A和酸B的电离指数，条件是当它们具有多个值时，它们代表其中的最小pKa。 沉淀分离有机酸A后的结晶母液在分离出酸B，然后分离出酸B的铵盐后再循环用于反应结晶步骤。 酸B的铵盐分解成酸B和氨，分别在生物转化步骤中再循环用于反应结晶步骤和中和剂。

公开(公告)号：US07223886B2

公开(公告)日：2007-05-29

申请号：US10708420

申请日：2004-03-02

申请人： Mark O. Scates ,  David A. Trueba ,  Raymond J. Zinobile

发明人： Mark O. Scates ,  David A. Trueba ,  Raymond J. Zinobile

IPC分类号： C07C51/10 ,  C07C51/42 ,  C07C45/78

CPC分类号： C07C51/44 ,  C07C51/48 ,  C07C53/08

摘要： An improvement of the methanol carbonylation process for manufacturing acetic acid is disclosed. Specifically disclosed is a method for reducing the formation of alkyl iodides and C3-8 carboxylic acids by removing permanganate reducing compounds (“PRC's”) from the light phase of the condensed light ends overhead stream, including (a) distilling the light phase to yield a PRC enriched overhead stream; and (b) extracting the third overhead stream with water in at least two consecutive stages and separating therefrom one or more aqueous streams containing PRC's.

摘要翻译： 公开了用于制备乙酸的甲醇羰基化方法的改进。 具体公开的是通过从冷凝的轻馏分塔顶液流的轻相中除去高锰酸盐还原化合物（“PRC's”）来减少烷基碘和C 3-8羧酸的形成的方法，包括（ a）蒸馏轻相以产生PRC富集的塔顶馏出物; 和（b）在至少两个连续的阶段用水提取第三塔顶流，并从中分离含有PRC的一种或多种含水物流。