公开(公告)号：US20050000936A1

公开(公告)日：2005-01-06

申请号：US10613193

申请日：2003-07-03

Applicant: Ulrich Boettiger ,  Scott Light

Inventor： Ulrich Boettiger ,  Scott Light

IPC: C23F1/00 ,  G03F7/004 ,  G03F7/20 ,  G03F7/40 ,  H01L21/302 ,  H01L21/311 ,  H01L21/76

CPC classification number: G03F7/2024 ,  G03F7/0045 ,  G03F7/40

Abstract: The invention includes methods by which the size and shape of photoresist-containing masking compositions can be selectively controlled after development of the photoresist. For instance, photoresist features can be formed over a substrate utilizing a photolithographic process. Subsequently, at least some of the photoresist features can be exposed to actinic radiation to cause release of a substance from the photoresist. A layer of material is formed over the photoresist features and over gaps between the features. The material has a solubility in a solvent which is reduced when the material interacts with the substance released from the photoresist. The solvent is utilized to remove portions of the material which are not sufficiently proximate to the photoresist to receive the substance, selectively relative to portions which are sufficiently proximate to the photoresist. The photoresist features can be exposed to the actinic radiation either before or after forming the layer of material.

公开(公告)号：US08779483B2

公开(公告)日：2014-07-15

申请号：US13365067

申请日：2012-02-02

Applicant: Kenneth Edward Salsman ,  Ulrich Boettiger ,  Dmitry Bakin ,  Curtis W. Stith

Inventor： Kenneth Edward Salsman ,  Ulrich Boettiger ,  Dmitry Bakin ,  Curtis W. Stith

IPC: H01L31/02 ,  H01L27/146

CPC classification number: H01L27/14625 ,  H01L27/14603

Abstract: Electronic devices may be provided with imaging modules that include plasmonic light collectors. Plasmonic light collectors may be configured to exploit an interaction between incoming light and plasmons in the plasmonic light collector to alter the path of the incoming light. Plasmonic light collectors may include one or more spectrally tuned plasmonic image pixels configured to preferentially trap light of a given frequency. Spectrally tuned plasmonic image pixels may include plasmonic structures formed form a patterned metal layer over doped silicon layers. Doped silicon layers may be interposed between plasmonic structures and a reflective layer. Plasmonic image pixels may be used to absorb and detect as much as, or more than, ninety percent of incident light at wavelengths ranging from the infrared to the ultraviolet. Plasmonic image pixels that capture light of different colors may be arranged in patterned arrays to form imager modules or imaging spectrometers for optofluidic microscopes.

Abstract translation: 电子设备可以设置有包括等离子体激光收集器的成像模块。 等离子体光收集器可以被配置为利用等离子体光收集器中的入射光和等离子体激元之间的相互作用来改变入射光的路径。 等离子体光收集器可以包括被配置为优先捕获给定频率的光的一个或多个频谱调谐等离子体像图像。 光谱调谐等离子体激元图像像素可以包括由掺杂硅层上的图案化金属层形成的等离子体结构。 掺杂的硅层可以介于等离子体激元结构和反射层之间。 等离子体像图像可用于吸收和检测多达或多于百分之九十的入射光，其范围从红外至紫外。 捕获不同颜色的光的等离子体像图像可以以图案化阵列布置以形成用于光流体显微镜的成像器模块或成像光谱仪。

公开(公告)号：US08466437B2

公开(公告)日：2013-06-18

申请号：US13165005

申请日：2011-06-21

Applicant: Ulrich Boettiger

Inventor： Ulrich Boettiger

IPC: F21V9/16 ,  H01L27/146 ,  G01T1/20

CPC classification number: G01N21/6456 ,  G01N21/6454

Abstract: A compact image sensor for imaging radiation emitted by fluorescing objects exposed to excitation light is disclosed. The compact image sensor includes a light guide defining a longitudinal axis for channeling radiation emitted by the fluorescing object; a reflective surface defined on the light guide that is oriented at an angle with respect to the longitudinal axis of the light guide to reflect the excitation light away from a detector of the image sensor; and the detector positioned at an end of the light guide for imaging radiation emitted by the fluorescing object. Also disclosed is a fluorescence imaging system for imaging radiation emitted by a fluorescing object to be imaged by compact image sensor and a method of fluorescence imaging.

Abstract translation: 公开了一种紧凑型图像传感器，用于对暴露于激发光的荧光物体发射的辐射进行成像。 紧凑型图像传感器包括限定用于引导由荧光物体发射的辐射的纵向轴线的光导体; 限定在所述光导上的反射表面，所述反射表面相对于所述光导的纵向轴线以一定角度定向，以将所述激发光反射离开所述图像传感器的检测器; 并且所述检测器位于所述光导的端部，用于成像由所述荧光物体发射的辐射。 还公开了一种荧光成像系统，用于对通过紧凑型图像传感器成像的荧光物体发射的辐射和荧光成像的方法进行成像。

公开(公告)号：US20120200749A1

公开(公告)日：2012-08-09

申请号：US13188811

申请日：2011-07-22

Applicant: Ulrich Boettiger ,  Swarnal Borthakur ,  Jeffrey Mackey ,  Brian Vaartstra ,  Marc Sulfridge

Inventor： Ulrich Boettiger ,  Swarnal Borthakur ,  Jeffrey Mackey ,  Brian Vaartstra ,  Marc Sulfridge

IPC: H04N9/04

CPC classification number: H04N5/2254 ,  H01L27/14621 ,  H01L27/14629 ,  H04N5/32 ,  H04N5/359

Abstract: An imaging system may include an image sensor configured to image materials at near field imaging ranges from the image sensor. Near field imaging ranges may be on the scale of 1-10 pixel sizes from the image sensor. The materials being imaged may be fluorescent materials that emit radiation at fluorescent wavelengths when the materials are exposed to radiation at excitation wavelengths. The image sensor may include color filter materials that block radiation at excitation wavelengths while transmitting radiation at fluorescent wavelengths. The image sensor may include light guides that reduce cross-talk between pixels and improve localization of emitted radiation, thereby allowing the image sensor to determine which pixel(s) is (are) located beneath the materials being imaged. The light guides may include may include sloped sidewalls and may include reflective sidewalls, which may improve radiation collection (e.g., efficiency) and localization of emitted radiation.

Abstract translation: 成像系统可以包括图像传感器，其构造成在来自图像传感器的近场成像范围内成像材料。 近场成像范围可以是来自图像传感器的1-10个像素尺寸的尺度。 正在成像的材料可以是当材料暴露于激发波长的辐射时以荧光波长发射辐射的荧光材料。 图像传感器可以包括在激发波长处阻挡辐射同时传输荧光波长的辐射的滤色器材料。 图像传感器可以包括减少像素之间的串扰并且改善发射的辐射的定位的光导，从而允许图像传感器确定位于被成像材料之下的哪个像素。 光导可以包括倾斜的侧壁并且可以包括反射侧壁，其可以改进辐射收集（例如，效率）和发射的辐射的定位。

公开(公告)号：US20120147228A1

公开(公告)日：2012-06-14

申请号：US12968076

申请日：2010-12-14

Applicant: Jacques Duparré ,  Ulrich Boettiger

Inventor： Jacques Duparré ,  Ulrich Boettiger

IPC: H04N9/097

CPC classification number: H04N9/045 ,  H01L27/14621 ,  H01L27/14625

Abstract: An imaging system may include an image sensor and lenses on a substrate. The lenses may focus light onto the image sensor. The imaging system may include multiple optical channels, each of which directs light at a particular wavelength or range of wavelengths to a particular region of the image sensor. The imaging system may include optical crosstalk suppression structures that reduce or minimize optical crosstalk between the optical channels. The optical crosstalk suppression structures may include, for each optical channel, at least a pair of matching color filters. The color filters may keep any light that leaks between optical channels from reaching the image sensor.

Abstract translation: 成像系统可以包括图像传感器和基板上的透镜。 透镜可将光聚焦到图像传感器上。 成像系统可以包括多个光学通道，每个光学通道将特定波长或波长范围的光引导到图像传感器的特定区域。 成像系统可以包括光学串扰抑制结构，其减少或最小化光信道之间的光串扰。 对于每个光通道，光学串扰抑制结构可以包括至少一对匹配的滤色器。 滤色器可以保持在光学通道之间泄漏的任何光到达图像传感器。

公开(公告)号：US20120045787A1

公开(公告)日：2012-02-23

申请号：US13183379

申请日：2011-07-14

Applicant: Ulrich Boettiger

Inventor： Ulrich Boettiger

IPC: C12Q1/02 ,  C12M1/34 ,  G01N21/00

CPC classification number: G01N21/05 ,  G01N21/03 ,  G01N2021/0325 ,  G01N2021/0346 ,  G02B21/34

Abstract: Micro-carrier systems may be used to carry and identify sample materials through an analysis system. Analysis systems may include an image sensor integrated circuit containing image sensor pixels. A channel containing a fluid with particles such as cells may be formed on top of the image sensor. Micro-carriers may be used to carry the cells in the fluid. Micro-carriers may have identifier regions and active regions. Identifier regions may include coded information identifying cells, fluid samples, or other materials carried in the active region. Active regions may carry reagents, trapping agents, cells or other sample materials. Active regions may be formed on a surface of a micro-carrier or may be formed in a cavity inside the micro-carrier. Micro-carriers may include magnetic control structures that can be used to guide, rotate, accelerate or position micro-carriers.

Abstract translation: 微载体系统可用于通过分析系统携带和识别样品材料。 分析系统可以包括包含图像传感器像素的图像传感器集成电路。 可以在图像传感器的顶部上形成包含诸如细胞等颗粒的流体的通道。 微载体可用于将细胞携带在流体中。 微载波可以具有标识符区域和活动区域。 标识符区域可以包括识别细胞，流体样品或在活性区域中携带的其它物质的编码信息。 活性区域可携带试剂，捕集剂，细胞或其他样品材料。 活性区域可以形成在微载体的表面上，或者可以形成在微载体内的空腔中。 微载体可以包括可用于引导，旋转，加速或定位微载体的磁性控制结构。

公开(公告)号：US20120044339A1

公开(公告)日：2012-02-23

申请号：US13114980

申请日：2011-05-24

Applicant: Curtis W. Stith ,  Dmitry Bakin ,  Ulrich Boettiger ,  Kenneth Edward Salsman

Inventor： Curtis W. Stith ,  Dmitry Bakin ,  Ulrich Boettiger ,  Kenneth Edward Salsman

IPC: H04N7/18

CPC classification number: G01N21/6458 ,  B01L3/502715

Abstract: An image sensor integrated circuit may contain image sensor pixels. A channel containing a fluid with particles such as cells may be formed on top of the image sensor. The image sensor pixels may form light sensors and imagers. The imagers may gather images of the cells or other particles as the fluid passes over the imagers. The channel may have multiple branches. Gating structures and other fluid control structures may control the flow of fluid through the channel branches. Portions of the channel may be used to form chambers. The chambers may each be provided with one or more light sensors, light sources, and color filters to alter the color of illumination form a light source, one or more reactants such as dyes, antigens, and antibodies, and heaters. The branches may route the fluid to respective chambers each of which has a different set of capabilities.

Abstract translation: 图像传感器集成电路可以包含图像传感器像素。 可以在图像传感器的顶部上形成包含诸如细胞等颗粒的流体的通道。 图像传感器像素可以形成光传感器和成像器。 当流体通过成像器时，成像器可以收集细胞或其他颗粒的图像。 频道可能有多个分支。 浇口结构和其他流体控制结构可以控制通过通道分支的流体的流动。 可以使用通道的一部分来形成室。 每个室可以各自设置有一个或多个光传感器，光源和滤色器，以改变来自光源的照明的颜色，一种或多种反应物，例如染料，抗原和抗体，以及加热器。 分支可以将流体路由到各自具有不同能力集合的室。

公开(公告)号：US20110180695A1

公开(公告)日：2011-07-28

申请号：US13082549

申请日：2011-04-08

Applicant: Jin Li ,  Jiutao Li ,  Ulrich Boettiger ,  Loriston Ford

Inventor： Jin Li ,  Jiutao Li ,  Ulrich Boettiger ,  Loriston Ford

IPC: H01J40/14

CPC classification number: H01L27/14627 ,  G02B3/0018 ,  G02B3/0037 ,  G02B3/0056

Abstract: A microlens structure includes lower lens layers on a substrate. A sputtered layer of glass, such as silicon oxide, is applied over the lower lens layers at an angle away from normal to form upper lens layers that increase the effective focal length of the microlens structure. The upper lens layers can be deposited in an aspherical shape with radii of curvature longer than the lower lens layers. As a result, small microlenses can be provided with longer focal length. The microlenses are arranged in arrays for use in imaging devices.

Abstract translation: 微透镜结构包括在基底上的较低透镜层。 将溅射的玻璃层（例如氧化硅）施加在下透镜层上以与法线成一定角度以形成增加微透镜结构的有效焦距的上透镜层。 上透镜层可以沉积成具有比下透镜层更长的曲率半径的非球面形状。 结果，可以提供较小焦距的小微透镜。 微透镜被布置成阵列以用于成像装置。

公开(公告)号：US20100270458A1

公开(公告)日：2010-10-28

申请号：US12429728

申请日：2009-04-24

Applicant: Rick Lake ,  Ulrich Boettiger ,  Shashikant Hegde ,  Jacques Duparre

Inventor： Rick Lake ,  Ulrich Boettiger ,  Shashikant Hegde ,  Jacques Duparre

IPC: H01L27/00 ,  H01L23/48 ,  H01L21/50 ,  H01L31/0232

CPC classification number: H01L24/16 ,  H01L21/76898 ,  H01L23/481 ,  H01L24/81 ,  H01L2224/13099 ,  H01L2224/16237 ,  H01L2224/81141 ,  H01L2224/81191 ,  H01L2224/83191 ,  H01L2924/00011 ,  H01L2924/00014 ,  H01L2924/01006 ,  H01L2924/01013 ,  H01L2924/01029 ,  H01L2924/01033 ,  H01L2924/01046 ,  H01L2924/01047 ,  H01L2924/01079 ,  H01L2924/014 ,  H01L2924/14 ,  H01L2924/1433 ,  H01L2924/1461 ,  H01L2924/351 ,  H05K3/32 ,  H05K3/4007 ,  H05K2201/09045 ,  H01L2924/00 ,  H01L2224/0401

Abstract: Various embodiments include interconnects for semiconductor structures that can include a first conductive structure, a second conductive structure and a non-hardening liquid conductive material in contact with the first and second structure. Other embodiments include semiconductor components and imager devices using the interconnects. Further embodiments include methods of forming a semiconductor structure and focusing methods for an imager device.

Abstract translation: 各种实施例包括用于半导体结构的互连，其可以包括与第一和第二结构接触的第一导电结构，第二导电结构和非硬化液体导电材料。 其他实施例包括使用互连的半导体部件和成像器件。 另外的实施例包括形成半导体结构的方法和用于成像器装置的聚焦方法。

公开(公告)号：US07646551B2

公开(公告)日：2010-01-12

申请号：US11987868

申请日：2007-12-05

Applicant: Jin Li ,  Jiutao Li ,  Ulrich Boettiger

Inventor： Jin Li ,  Jiutao Li ,  Ulrich Boettiger

IPC: G02B3/00

CPC classification number: G02B3/0087 ,  G02B3/08 ,  H01L27/14605 ,  H01L27/14627 ,  H01L27/14685 ,  H01L31/02327

Abstract: A method, apparatus and system providing a microlens having a substantially flat upper surface and having a plurality of holes arranged in a pattern in a microlens material which produces a focal point at a desired location.

Abstract translation: 一种提供微透镜的方法，装置和系统，该微透镜具有基本上平坦的上表面，并且具有以微透镜材料排列成图案的多个孔，该微透镜材料在期望位置处产生焦点。