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公开(公告)号：US20170304438A1
公开(公告)日：2017-10-26
申请号：US15440917
申请日：2017-02-23
Applicant: Genentech, Inc.
Inventor： Andrew Polson , Shang-Fan Yu , Yu-Waye Chu , Michael Wenger
IPC: A61K39/395 , A61K45/06 , C07K16/28 , A61K31/4184 , C07K16/30 , A61K39/00
CPC classification number: A61K31/4184 , A61K31/454 , A61K31/553 , A61K31/635 , A61K39/3955 , A61K39/39558 , A61K45/06 , A61K47/6803 , A61K47/6849 , A61K47/6867 , A61K47/6889 , A61K2039/507 , A61K2039/54 , A61K2039/545 , A61K2300/00 , C07K16/2803 , C07K16/2887 , C07K16/3061 , C07K2317/24
Abstract: Provided herein are methods of treating B-cell proliferative disorders in particular Follicular Lymphoma and/or Diffuse Large B-Cell Lymphoma using immunoconjugates comprising anti-CD79b antibodies in combination with additional therapeutic agents.
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公开(公告)号：US20170290920A1
公开(公告)日：2017-10-12
申请号：US15497656
申请日：2017-04-26
Applicant: MEDIMMUNE LIMITED , GENENTECH, INC.
Inventor： Paul Polakis , Andrew Polson , Susan Diane Spencer , Shang-Fan Yu , John A. Flygare , Janet L. Gunzner-Toste , Thomas H. Pillow , Philip Wilson Howard , Luke Masterson
IPC: A61K47/48 , A61K31/5517 , C07D487/16 , C07K19/00
CPC classification number: A61K31/5517 , A61K31/551 , A61K45/06 , A61K47/6809 , A61K47/6849 , A61K47/6867 , A61K47/6877 , A61K2300/00
Abstract: The invention provides anti-CD22 antibodies and immunoconjugates and methods of using the same.
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公开(公告)号：US20160159906A1
公开(公告)日：2016-06-09
申请号：US14960015
申请日：2015-12-04
Applicant: Genentech, Inc.
Inventor： Liping L. Sun , Yvonne Man-Yee Chen , Mark S. Dennis , Allen J. Ebens, JR. , Andrew Polson
CPC classification number: C07K16/2803 , A61K47/6803 , A61K47/6849 , A61K2039/505 , C07K16/2809 , C07K2317/21 , C07K2317/24 , C07K2317/31 , C07K2317/34 , C07K2317/55 , C07K2317/622 , C07K2317/92
Abstract: The invention provides anti-CD79b antibodies and methods of using the same.
Abstract translation: 本发明提供抗CD79b抗体及其使用方法。
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Patent Agency Ranking
公开(公告)号：US20160082120A1
公开(公告)日：2016-03-24
申请号：US14863125
申请日：2015-09-23
Applicant: Genentech, Inc.
Inventor： Andrew Polson , Shang-Fan Yu , Yu-Waye Chu , Michael Wenger
IPC: A61K47/48 , A61K31/4184 , A61K39/395
CPC classification number: A61K31/4184 , A61K31/454 , A61K31/553 , A61K31/635 , A61K39/3955 , A61K39/39558 , A61K45/06 , A61K47/6803 , A61K47/6849 , A61K47/6867 , A61K47/6889 , A61K2039/507 , A61K2039/54 , A61K2039/545 , A61K2300/00 , C07K16/2803 , C07K16/2887 , C07K16/3061 , C07K2317/24
Abstract: Provided herein are methods of treating B-cell proliferative disorders in particular Follicular Lymphoma and/or Diffuse Large B-Cell Lymphoma using immunoconjugates comprising anti-CD79b antibodies in combination with additional therapeutic agents.
Abstract translation: 本文提供了使用包含抗CD79b抗体与附加治疗剂组合的免疫缀合物来治疗特别是滤泡性淋巴瘤和/或弥漫性大B细胞淋巴瘤的B细胞增殖性疾病的方法。
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公开(公告)号：US09017951B2
公开(公告)日：2015-04-28
申请号：US13673565
申请日：2012-11-09
Applicant: Genentech, Inc.
Inventor： Kristi Elkins , Andrew Polson , Allen Ebens , Camelia Adams , Bing Zheng , Jagath R. Junutula , Jo-Anne Hongo , Yan Wu
IPC: G01N33/53 , G01N33/574 , A61K39/395 , A61K45/06 , C07K16/28 , A61K31/69 , A61K39/00
CPC classification number: A61K39/3955 , A61K31/69 , A61K39/395 , A61K45/06 , A61K2039/505 , C07K16/283 , C07K2317/24 , C07K2317/92 , A61K2300/00
Abstract: A method of determining the presence of FcRH5 in a biological sample suspected of containing FcRH5 is provided comprising exposing the biological sample to an isolated monoclonal anti-FcRH5 antibody.
Abstract translation: 提供了一种确定怀疑含有FcRH5的生物样品中FcRH5存在的方法，包括将生物样品暴露于分离的单克隆抗FcRH5抗体。
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公开(公告)号：US20140322129A1
公开(公告)日：2014-10-30
申请号：US14207878
申请日：2014-03-13
Applicant: Genentech, Inc.
Inventor： Steven R. Leong , Andrew Polson , Paul Polakis , Yan Wu , Wei-Ching Liang , Ron Firestein
IPC: C07K16/28 , A61K45/06 , A61K51/10 , A61K38/05 , A61K31/704 , A61K47/48 , G01N33/574
CPC classification number: C07K16/3015 , A61K31/5377 , A61K31/5517 , A61K39/3955 , A61K45/06 , A61K47/6803 , A61K47/6849 , A61K51/1027 , A61K2039/505 , C07K16/2827 , C07K16/3069 , C07K2317/24 , C07K2317/33 , C07K2317/34 , C07K2317/41 , C07K2317/567 , C07K2317/77 , C07K2317/92 , G01N33/57492 , A61K2300/00
Abstract: The invention provides anti-B7-H4 antibodies and immunoconjugates and methods of using the same.
Abstract translation: 本发明提供抗B7-H4抗体和免疫缀合物及其使用方法。
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公开(公告)号：US20140030281A1
公开(公告)日：2014-01-30
申请号：US13936284
申请日：2013-07-08
Applicant: Genentech, Inc.
Inventor： Paul Polakis , Andrew Polson , Susan Diane Spencer , Shang-Fan Yu , Bing Zheng
IPC: A61K47/48 , A61K45/06 , A61K31/706
CPC classification number: A61K47/6807 , A61K31/706 , A61K45/06 , A61K47/6809 , A61K47/6849 , A61K47/6867
Abstract: The invention provides anti-CD22 antibodies and immunoconjugates and methods of using the same.
Abstract translation: 本发明提供抗CD22抗体和免疫缀合物及其使用方法。
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公开(公告)号：US08617559B2
公开(公告)日：2013-12-31
申请号：US13682581
申请日：2012-11-20
Applicant: Genentech, Inc.
Inventor： Kristi Elkins , Andrew Polson , Allen Ebens , Camelia Adams , Bing Zheng , Jagath R. Junutula , Jo-Anne Hongo , Yan Wu
IPC: A61K39/00
CPC classification number: G01N33/6854 , A61K31/138 , A61K31/4196 , A61K31/454 , A61K31/4745 , A61K31/517 , A61K31/56 , A61K31/568 , A61K31/5685 , A61K31/69 , A61K33/24 , A61K38/19 , A61K39/0011 , A61K39/39533 , A61K39/39558 , A61K47/6803 , A61K47/6849 , A61K2039/505 , C07K16/2803 , C07K16/283 , C07K2317/24 , C07K2317/522 , C07K2317/73 , G01N33/574 , G01N33/6857 , Y02A50/473
Abstract: The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
Abstract translation: 本发明涉及可用于治疗哺乳动物造血肿瘤的物质组合物，以及使用这些物质组合物的方法。
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