公开(公告)号：US20220354922A1

公开(公告)日：2022-11-10

申请号：US17764985

申请日：2020-09-25

Applicant: KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION ,  ANDONG NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION

Inventor： Moon-Chang BAEK ,  Young-Eun CHO ,  Dong Ha KIM

IPC: A61K36/9068 ,  A23L33/17 ,  A23L33/105 ,  A61K38/44 ,  A61K38/48

Abstract: The present invention relates to extracellular vesicles derived from ginger (Zingiber officinale) and a use thereof, and provides: extracellular vesicles which are derived from ginger and have anticancer activity, a pharmaceutical composition and a health functional food composition which is for preventing or treating cancer and contains the extracellular vesicles as an active ingredient. The ginger-derived extracellular vesicles can penetrate into cancer cells, have excellent anticancer activity, such as inhibiting the proliferation, infiltration and migration of cancer cells, and thus may be provided as an effective anticancer composition.

公开(公告)号：US20220226263A1

公开(公告)日：2022-07-21

申请号：US17615008

申请日：2020-05-27

Applicant: EWHA UNIVERSITY -INDUSTRY COLLABORATION FOUNDATION ,  CHA UNIVERSITY INDUSTRY -ACADEMIC COOPERATION FOUNDATION ,  INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YOSEI UNIVERSITY

Inventor： Youngjoo Kwon ,  Soo-Yeon Hwang ,  Hyunji Jo ,  Seojong Park ,  Younghwa Na ,  Eosu Kim ,  Jihyeon Jeong ,  Minsun Park ,  Hyunjeong Kim

IPC: A61K31/136 ,  A61K31/18 ,  A61K31/4453 ,  A61K31/495 ,  A61K45/06 ,  A61P35/00

Abstract: A composition according to the present disclosure may be very effectively used not only to prevent, ameliorate or treat cancer, but also to inhibit metastasis of cancer, by inhibiting the growth of cancer cells and very effectively inhibiting the metastasis of cancer cells to other tissues.

公开(公告)号：US20220112527A1

公开(公告)日：2022-04-14

申请号：US17288761

申请日：2019-10-28

Applicant: INDUSTRY-ACADEMIC COOPERATION FOUNDATION GYEONGSANG NATIONAL UNIVERSITY ,  KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION

Inventor： Seon Won KIM ,  Seong Hee JEONG ,  Kyung Jin KIM ,  Zada BAKHT

IPC: C12P7/28 ,  C12N15/52 ,  C12N1/20 ,  C12N9/10 ,  C12N9/16

Abstract: A method for biologically producing acetin such as monoacetin, diacetin, or triacetin according to an embodiment of the present disclosure includes reacting acetyl-CoA with glycerol in the presence of a first O-acetyl transferase to obtain the acetin. With the method, acetin which is sustainable and safe, and has more excellent quality while not causing environmental pollution may be obtained.

公开(公告)号：US20220054504A1

公开(公告)日：2022-02-24

申请号：US17389449

申请日：2021-07-30

Applicant: Gachon University of Industry-Academic cooperation Foundation ,  Eulji University Industry Academy Cooperation Foundation ,  Kyungpook National University Industry-Academic Cooperation Foundation

Inventor： Dongwoo KHANG ,  Jun-Young PARK ,  Youn Joo KANG ,  Sang-Hyun KIM ,  Song KWON

IPC: A61K31/573 ,  A61K47/69 ,  A61P29/00

Abstract: The present invention provides a novel therapeutic agent for treating inflammatory diseases which reduces the pro-inflammatory response and increases M2 macrophages according to the repolarization of macrophages, thereby exhibiting fewer side effects and excellent anti-inflammatory effects even at low doses compared to conventional steroid anti-inflammatory agent.

公开(公告)号：US20200380297A1

公开(公告)日：2020-12-03

申请号：US16716881

申请日：2019-12-17

Applicant: AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION ,  Dongguk University Industry-Academic Cooperation Foundation

Inventor： Won Jun HWANG ,  Ho Chul SIN ,  Dong Yi KIM ,  Soo Chul LIM ,  Dae Kwan KO

IPC: G06K9/62 ,  G06K9/68

Abstract: A method of measuring an interaction force includes: generating feature maps corresponding to a plurality of sequential images; generating pooling maps respectively corresponding to feature map groups including a predetermined number of feature maps among the feature maps; generating attention maps corresponding to the pooling maps; and sequentially receiving feature maps modified based on the attention maps and outputting interaction force information.

公开(公告)号：US20200153611A1

公开(公告)日：2020-05-14

申请号：US16673971

申请日：2019-11-05

Applicant: DONGGUK UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION ,  Industry-Academic Cooperation Foundation, Chosun University

Inventor： Dae Woon LIM ,  Young Sik KIM ,  Ki Soon YU

IPC: H04L9/06 ,  H04L9/14 ,  H04L9/00 ,  H04L9/08 ,  H04L9/32 ,  H03M13/11 ,  H03M13/09

Abstract: Disclosed is an electronic device for performing code-based encryption supporting integrity verification of a message and an operating method thereof. When a data transmission side encrypts a message through code-based encryption and transmits the encrypted message to a data reception apparatus, the data transmission side is allowed to use a hash value generated based on a part of the message as an error in code-based encryption to support the data reception apparatus to verify an integrity of a received message by using the hash value.

公开(公告)号：US10383844B2

公开(公告)日：2019-08-20

申请号：US15986033

申请日：2018-05-22

Applicant: College of Medicine Pochon Cha University Industry—Academic Cooperation Foundation ,  EWHA University—Industry Collaboration Foundation ,  Industry—Academic Cooperation Foundation, Yonsei University

Inventor： Younghwa Na ,  Yun-Sil Lee ,  Jae Ho Cho

IPC: A61K31/353 ,  A61K31/38 ,  A61P11/00

Abstract: A composition for prevention or treatment of pulmonary fibrosis comprising chromenone derivatives represented by Formula I of the present invention or pharmaceutically acceptable salts thereof as an active ingredient, produces altered heat shock protein 27 (HSP27) dimers, thereby preventing normal HSP27 non-phosphorylated polymers from performing a chaperone function and reducing a cell protection function that chaperone originally performs. Thus the inventive composition has a remarkable inhibitory effect on pulmonary fibrosis, in particular, an irradiation-induced pulmonary fibrosis phenomenon.

公开(公告)号：US20170161397A1

公开(公告)日：2017-06-08

申请号：US15348871

申请日：2016-11-10

Applicant: Industry Academic Cooperation Foundation of Yeungnam University ,  INDUSTRY-ACADEMIC COOPERATION FOUNDATION, KUNSAN NATIONAL UNIVERSITY

Inventor： Gyu Sang CHOI ,  Byung Won ON ,  In Gyu LEE

IPC: G06F17/30

CPC classification number: G06F16/9014

Abstract: The present disclosure relates to a method for hash collision detection based on the sorting unit of the bucket designed to reduce the future search time by pre-aligning the database in the bucket and to enhance the efficiency in a search within the database. The present disclosure, a method for hash collision detection based on the sorting unit of the bucket using conventional separate chaining method, comprises aligning records in a single bucket of a directory in ascending order or descending order and maintaining the alignment of records in the bucket when new records are added to the directory.

公开(公告)号：US09669103B2

公开(公告)日：2017-06-06

申请号：US15074443

申请日：2016-03-18

Applicant: KOREA NATIONAL UNIVERSITY OF TRANSPORTATION Industry-Academic Cooperation Foundation ,  THE CATHOLIC UNIVERSITY OF KOREA INDUSTRY-ACADEMIC COOPERATION FOUNDATION

Inventor： Yong Kyu Lee ,  Sung Hoon Kang ,  Sang Joon Lee ,  In Kyu Park ,  Kwang Jae Cho ,  Mohammed Nurunnabi

IPC: C08B37/08 ,  C01G7/00 ,  C07H21/02 ,  C07H21/04 ,  A61K31/7032 ,  A61K47/48 ,  C12N15/113 ,  A61K31/713

CPC classification number: A61K31/713 ,  A61K47/6939 ,  C12N15/111 ,  C12N15/113 ,  C12N2310/14 ,  C12N2310/351 ,  C12N2320/32

Abstract: Disclosed are a metal-nanoparticle-based liver-specific nucleic acid delivery system, a method of manufacturing the same, and a liver disease treatment composition containing the same. The liver-specific nucleic acid delivery system is coated with a bile acid-glycol chitosan polymer, so that it provides excellent liver-tissue specificity and high absorbance through digestive canals. Since the nucleic acid of the nucleic acid delivery system is coated with the bile acid-glycol chitosan polymer, it can be protected from decomposition of enzymes and the like inside a living organism. The liver-specific nucleic acid delivery system can be developed as an oral-administrating liver-disease treatment.

公开(公告)号：US20170004899A1

公开(公告)日：2017-01-05

申请号：US15196820

申请日：2016-06-29

Applicant: Industry-Academic Cooperation Foundation, Yonsei University ,  Incheon University Industry Academic Cooperation Foundation

Inventor： TAEYOON LEE ,  JONG HYUN AHN ,  Juree HONG ,  Jae-Bok LEE ,  Han-Bo-Ram LEE

IPC: H01B1/04 ,  H01B13/00

CPC classification number: H01B1/04

Abstract: Provided are method for healing defect of conductive layer, method for forming metal-carbon compound layer, 2D nano materials, and transparent electrode and method for manufacturing the same. According to an embodiment of present invention, the method for healing defect of conductive layer comprises: forming a conductive layer on a first metal substrate; contacting the first metal substrate with a salt solution containing a second metal in an ionic form, and forming a second metal particle at least in a portion of a conductive area, the second metal having greater reduction potential than a first metal.

Abstract translation: 提供导电层的愈合缺陷的方法，金属 - 碳化合物层的形成方法，2D纳米材料和透明电极及其制造方法。 根据本发明的一个实施方案，用于治疗导电层缺陷的方法包括：在第一金属基底上形成导电层; 使第一金属基底与含有离子形式的第二金属的盐溶液接触，并且在导电区域的至少一部分中形成第二金属颗粒，第二金属具有比第一金属更大的还原电位。