Method of inducing immune tolerance via blood/lymph flow-restricted bone marrow transplantation
    59.
    发明授权
    Method of inducing immune tolerance via blood/lymph flow-restricted bone marrow transplantation 有权
    通过血液/淋巴流限制性骨髓移植诱导免疫耐受的方法

    公开(公告)号:US07138144B2

    公开(公告)日:2006-11-21

    申请号:US10237033

    申请日:2002-09-09

    Applicant: Nadir Askenasy

    Inventor: Nadir Askenasy

    CPC classification number: A61K39/001 A61K2035/122 A61K2035/124 Y10S514/885

    Abstract: A method of inducing tolerance to a transplant transplanted from a donor to a subject is disclosed. The method comprises (a) restricting outflow of a fluid from a portion of the circulatory system of the subject; and (b) administering a dose of bone marrow cells derived from the donor to a body part delimiting said portion of the circulatory system, prior to, concomitantly with or following transplantation of the transplant, thereby inducing tolerance to the transplant in the subject.

    Abstract translation: 公开了一种诱导从供体移植到受试者的移植耐受性的方法。 该方法包括(a)限制流体从受试者的循环系统的一部分流出; 和(b)在移植之前,伴随移植或随后移植移植物,将一定剂量的源自供体的骨髓细胞施用于限定循环系统的所述部分的身体部位,从而诱导对受试者的移植的耐受性。

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