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646 条记录 (耗时 0.041 秒)

    Medicinal herbal composition for treating infection
    51.
    发明授权
    Medicinal herbal composition for treating infection 有权
    用于治疗感染的药用草药组合物

    公开(公告)号：US08053002B2

    公开(公告)日：2011-11-08

    申请号：US12657212

    申请日：2010-01-15

    申请人： Paul Kiprono Chepkwony ,  Maria Medina ,  Mitchell Medina

    发明人： Paul Kiprono Chepkwony ,  Maria Medina ,  Mitchell Medina

    IPC分类号： A61K36/00

    CPC分类号： A61K36/38 ,  A61K36/47 ,  A61K36/76 ,  A61K2300/00

    摘要： Herbal compositions derived from Kenyan plants are provided for the treatment of HIV and other infectious diseases. The herbal compositions can include the extracts of up to 14 plants, including the root of Dovyalis abyssinica and Clutia robusta. Also provided are methods for extracting alkaloids and other compounds from the plants. Also provided are methods of treating a subject having an infectious disease, particularly HIV.

    摘要翻译： 衍生自肯尼亚植物的草药组合物用于治疗艾滋病毒和其他感染性疾病。 草药组合物可以包括多达14种植物的提取物，包括Dovyalis abyssinica和Clutia robusta的根。 还提供了从植物中提取生物碱和其它化合物的方法。 还提供了治疗具有感染性疾病，特别是HIV的受试者的方法。

    TREATMENT OF LUPUS NEPHRITIS USING LAQUINIMOD
    52.
    发明申请
    TREATMENT OF LUPUS NEPHRITIS USING LAQUINIMOD 有权
    使用LAQUINIMOD治疗LUPUS NEPHRITIS

    公开(公告)号：US20110218179A1

    公开(公告)日：2011-09-08

    申请号：US13039178

    申请日：2011-03-02

    申请人： Asi Haviv ,  Nora Tarcic

    发明人： Asi Haviv ,  Nora Tarcic

    IPC分类号： A61K31/4704 ,  A61P37/00 ,  A61K31/5377 ,  A61K31/573 ,  A61P9/10 ,  A61P33/06

    CPC分类号： A61K31/4704 ,  A61K9/14 ,  A61K31/47 ,  A61K31/5355 ,  A61K31/5377 ,  A61K31/573 ,  A61K36/47 ,  A61K47/02 ,  A61K2121/00 ,  A61K2300/00 ,  C07D215/22

    摘要： This invention provides a method of treating a subject afflicted with active lupus nephritis comprising periodically administering to the subject an amount of laquinimod or pharmaceutically acceptable salt thereof effective to treat the subject. This invention also provides laquinimod or pharmaceutically acceptable salt thereof for use in treating a subject afflicted with active lupus nephritis. This invention further provides a pharmaceutical composition comprising an amount of laquinimod or pharmaceutically acceptable salt thereof for use in treating a subject afflicted with active lupus nephritis.

    摘要翻译： 本发明提供一种治疗患有活动性狼疮性肾炎的受试者的方法，其包括向受试者施用一定量的有效治疗受试者的拉喹莫德或其药学上可接受的盐。 本发明还提供了用于治疗患有活动性狼疮性肾炎的受试者的拉喹莫德或其药学上可接受的盐。 本发明还提供一种药物组合物，其包含一定量的拉喹莫德或其药学上可接受的盐，用于治疗患有活动性狼疮性肾炎的受试者。

    Cosmetic composition with anti-free radical activity
    53.
    发明授权
    Cosmetic composition with anti-free radical activity 有权
    具有抗自由基活性的化妆品组合物

    公开(公告)号：US07988982B2

    公开(公告)日：2011-08-02

    申请号：US11883779

    申请日：2007-06-11

    申请人： Patrice Andre ,  Isabelle Renimel ,  Céline Godenir ,  Michel Hocquaux

    发明人： Patrice Andre ,  Isabelle Renimel ,  Céline Godenir ,  Michel Hocquaux

    IPC分类号： A61K8/02

    CPC分类号： A61K8/676 ,  A61K8/355 ,  A61K8/447 ,  A61K8/498 ,  A61K8/58 ,  A61K8/97 ,  A61K31/122 ,  A61K31/197 ,  A61K31/355 ,  A61K31/41 ,  A61K33/04 ,  A61K36/28 ,  A61K36/47 ,  A61K45/06 ,  A61K2800/522 ,  A61Q1/02 ,  A61Q17/04 ,  A61Q19/001 ,  A61Q19/004 ,  A61Q19/08 ,  A61K2300/00

    摘要： A cosmetic composition has an association of at least three of the following substances with anti-free radical activity, selected from: 1) ebselen; or idebenone; or an association of the two; and 2) at least one substance with anti-free radical activity, or at least two substances with anti-free radical activity for obtaining said association of at least three substances with anti-free radical activity, said substance(s) being selected from: a) a substance of chemical formula (I) below: in which: R=a linear or branched, saturated or unsaturated C1-C16 hydrocarbon chain; and R1, R2 and R3 are identical or different and are a hydrogen atom or a methyl or methoxy radical, and its esters; b) an extract of Edelweiss; c) an extract of Emblica; and d) N-acetylcysteine. The anti-free radical activity is greatly improved.

    摘要翻译： 化妆品组合物具有至少三种以下物质与抗自由基活性的缔合，所述物质选自：1）依贝硒; 或艾地苯醌; 或两者的协会; 和2）至少一种具有抗自由基活性的物质，或至少两种具有抗自由基活性的物质，用于获得至少三种具有抗自由基活性的物质的缔合，所述物质选自： a）以下化学式（I）的物质：其中：R =直链或支链，饱和或不饱和的C 1 -C 16烃链; 且R1，R2和R3相同或不同，为氢原子或甲基或甲氧基，及其酯; b）Edelweiss的提取物; c）Emblica的提取物; 和d）N-乙酰半胱氨酸。 抗自由基活性大大提高。

    INHIBITOR FOR GROWTH OF BACTERIA OF GENUS LEGIONELLA, BATH AGENT AND CLEANING AGENT
    55.
    发明申请
    INHIBITOR FOR GROWTH OF BACTERIA OF GENUS LEGIONELLA, BATH AGENT AND CLEANING AGENT 审中-公开
    抑菌剂，用于生长细菌，巴氏代谢和清洁剂

    公开(公告)号：US20110015411A1

    公开(公告)日：2011-01-20

    申请号：US12921554

    申请日：2009-02-26

    申请人： Takaki Goto ,  Syuichi Fukumoto

    发明人： Takaki Goto ,  Syuichi Fukumoto

    IPC分类号： C07D311/32

    CPC分类号： A01N65/18 ,  A01N43/16 ,  A01N65/00 ,  A61K8/97 ,  A61K31/352 ,  A61K36/47 ,  A61K2800/524 ,  A61Q19/10 ,  Y02A50/478

    摘要： A growth inhibitor of bacteria of the genus Legionella contains as an active ingredient a Macaranga tanarius extract extracted from Macaranga tanarius with an extraction solvent including at least an organic solvent. Alternatively, the growth inhibitor of bacteria of the genus Legionella contains as an active ingredient at least one selected from nymphaeol-A, nymphaeol-B, and nymphaeol-C. The growth inhibitor of bacteria of the genus Legionella is used by being blended to, for example, a bath agent or a cleaning agent.

    摘要翻译： 军团菌细菌的生长抑制剂含有从马齿苋（Macaranga tanarius）中萃取的含有至少一种有机溶剂的萃取溶剂作为活性成分。 或者，军团菌细菌的生长抑制剂含有选自淋巴酮-A，夜蛾酚B和夜蛾酚C中的至少一种作为活性成分。 通过与例如浴剂或清洁剂混合使用军团菌属细菌的生长抑制剂。

    ANTI-METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS AGENT AND ANTI-VANCOMYCIN-RESISTANT ENTEROCOCCUS AGENT
    56.
    发明申请
    ANTI-METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS AGENT AND ANTI-VANCOMYCIN-RESISTANT ENTEROCOCCUS AGENT 审中-公开
    抗甲氧西林耐药性黄连素代谢物和抗 - 抗生素耐药性肠炎药

    公开(公告)号：US20110008472A1

    公开(公告)日：2011-01-13

    申请号：US12921560

    申请日：2009-02-26

    申请人： Takaki Goto ,  Syuichi Fukumoto

    发明人： Takaki Goto ,  Syuichi Fukumoto

    IPC分类号： A61K36/47 ,  A61K31/353 ,  A61P31/04

    CPC分类号： A01N65/18 ,  A01N65/00 ,  A61K31/353 ,  A61K36/47 ,  C07D311/32

    摘要： An anti-methicillin-resistant Staphylococcus aureus agent (anti-MRSA agent) and an anti-vancomycin-resistant Enterococcus agent (anti-VRE agent) contain as an active ingredient an Oobagi extract extracted from Oobagi with an extraction solvent including at least an organic solvent. Alternatively, the anti-MRSA agent and the anti-VRE agent contain as an active ingredient at least one selected from nymphaeol-A, nymphaeol-B, and nymphaeol-C.

    摘要翻译： 含抗甲氧西林抗性金黄色葡萄球菌剂（抗MRSA试剂）和抗万古霉素耐药性肠球菌剂（anti-VRE试剂）含有从Oobagi提取的Oobagi提取物作为活性成分，提取溶剂包括至少一种有机 溶剂。 或者，抗MRSA试剂和抗VRE试剂含有选自淋巴酮-A，夜蛾B和睡莲C中的至少一种作为活性成分。

    Use of tropical root crops in dietary intervention strategies
    57.
    发明授权
    Use of tropical root crops in dietary intervention strategies 失效
    在饮食干预策略中使用热带根系作物

    公开(公告)号：US07854948B2

    公开(公告)日：2010-12-21

    申请号：US10682546

    申请日：2003-10-10

    申请人： K. M. Slimak

    发明人： K. M. Slimak

    IPC分类号： A61K36/00 ,  A61K9/00 ,  A61K47/00

    CPC分类号： A61K36/39 ,  A23L33/105 ,  A23L33/30 ,  A61K36/47 ,  A61K36/62 ,  A61K36/88 ,  A61K36/888 ,  A61K36/89 ,  A61K36/8945

    摘要： This invention relates to an effective dietary intervention plan. In one aspect all food is withheld for a period of at least 5 days, except for tropical root crops. In another aspect the invention relates to the treatment of various symptoms, conditions or diseases such as Diarrhea, constipation, congestion, eczema, asthma, fatigue, muscle weakness, tension, and spasms, irritable bowel syndrome, swelling, anxiety, multiple chemical sensitivities, moderate to extensive and moderate to severe symptoms due to food allergies, sensitivities, and intolerances, bloating, pain, headaches, leaky gut, hyperactivity, sleeping difficulties, severe underweight, eating disorders, obsessive, compulsive disorders, panic attacks, sensory sensitivities, Alzheimer's disease, acid reflux, irritability, delayed motor skills, delayed social skills, autism, PDD, infantile spasms, seizures by withholding from the patient for a period of at least 5 days all food except for concentrated forms of concentrated tropical root crops. Preferably the patient is also removed from external environmental sources of allergens. After the initial withholding period new foods may be introduced according to a particular selection and schedule.

    摘要翻译： 本发明涉及有效的饮食干预计划。 一方面，所有的食物都被禁止至少5天，除了热带根茎作物。 另一方面，本发明涉及各种症状，病症或疾病如腹泻，便秘，充血，湿疹，哮喘，疲劳，肌肉无力，紧张和痉挛，肠易激综合征，肿胀，焦虑，多种化学敏感性， 由于食物过敏，敏感性和不耐受，腹胀，疼痛，头痛，泄漏肠，多动，睡眠困难，严重体重不足，进食障碍，强迫症，强迫症，恐慌发作，感觉敏感性，阿尔茨海默氏症，中度至中度至重度症状 疾病，酸反流，烦躁，延迟的运动技能，延迟的社会技能，自闭症，PDD，婴儿痉挛，通过从患者中扣留至少5天的所有食物，除了浓缩形式的热带热带根系作物。 优选地，患者也从外部环境来源的过敏原​​中除去。 根据特定的选择和进度，最初的扣留期可能会引进新的食品。

    Novel Phyllanthus Extract
    59.
    发明申请
    Novel Phyllanthus Extract 有权
    小叶提取物

    公开(公告)号：US20100190726A1

    公开(公告)日：2010-07-29

    申请号：US12642877

    申请日：2009-12-21

    申请人： Aron Katz ,  Christopher Molloy ,  Mark Stuart Butler ,  Brinda Somanadhan

    发明人： Aron Katz ,  Christopher Molloy ,  Mark Stuart Butler ,  Brinda Somanadhan

    IPC分类号： A61K31/70 ,  B01D15/38 ,  A01H5/00 ,  C07H1/00 ,  A61P31/18

    CPC分类号： A61K36/47

    摘要： A method is described for producing an extract of Phyllanthus comprising the steps of: (a) extracting Phyllanthus components with a solvent; (b) fractionating the extract obtained in the preceding step on the basis of hydrophobicity; (c) collecting and combining fractions that correspond in hydrophobicity to elute fractions resulting from 10-50% methanol elution steps, wherein the elute fractions are obtained by low pressure vacuum liquid chromatography (VLC) using a C18 reversed-phase lipophilic column and a water/methanol gradient system, wherein the gradient system is based on an initial elution step of loading the column with 100% water, on intermediate elution steps with gradually decreasing water content and on a terminal elution step loading the column with 100% methanol; and (d) optionally drying the extract obtained in step (c). The invention also relates to an extract of Phyllanthus obtainable or obtained by the method or a fraction thereof and a Phyllanthus extract or fraction thereof comprising repandusinic acid, wherein the repandusinic acid is present at a concentration of at least 42 mg/g.

    摘要翻译： 描述了用于生产叶酸提取物的方法，包括以下步骤：（a）用溶剂萃取叶酸成分; （b）基于疏水性对前述步骤中获得的提取物进行分级; （c）将从疏水性对应的级分与从10-50％甲醇洗脱步骤得到的洗脱级分进行收集并合并，其中洗脱级分通过使用C18反相亲油柱和水的低压真空液相色谱（VLC）获得 /甲醇梯度系统，其中梯度系统基于在具有逐渐降低的水含量的中间洗脱步骤的情况下以100％水加载柱的初始洗脱步骤，以及在100％甲醇下加载柱的末端洗脱步骤; 和（d）任选地干燥步骤（c）中获得的提取物。 本发明还涉及通过该方法或其一部分获得或获得的珍珠提取物，以及含有还原性酸的叶酸提取物或其级分，其中所述还原性酸以至少42mg / g的浓度存在。