公开(公告)号：US20130225581A1

公开(公告)日：2013-08-29

申请号：US13810568

申请日：2011-07-15

申请人： Takayuki Furuta ,  Kazuo Kubo ,  Toshiyuki Atsumi ,  Maasa Yamanouchi

发明人： Takayuki Furuta ,  Kazuo Kubo ,  Toshiyuki Atsumi ,  Maasa Yamanouchi

IPC分类号： C07D495/04 ,  C07D401/14 ,  C07D413/14 ,  C07D401/12

CPC分类号： C07D495/04 ,  C07D401/12 ,  C07D401/14 ,  C07D413/14 ,  C07D417/14

摘要： The present invention provides a nitrogen-containing aromatic heterocyclic derivative represented by formula (I): [wherein W represents CR3 (wherein R3 represents a hydrogen atom or the like) or the like, R4 represents a hydrogen atom or the like, R5 represents a hydrogen atom or the like, R9 represents substituted imidazolyl, R12 and R13 may be the same or different, each represent a hydrogen atom or the like, R22 and R23 may be the same or different, each represent a hydrogen atom or the like, R24 represents a hydrogen atom or the like, Y represents C—R25 (wherein R25 represents a hydrogen atom or the like) or the like] or a pharmaceutically acceptable salt thereof and a FGFR inhibitor comprising, as an active ingredient, the nitrogen-containing aromatic heterocyclic derivative or the pharmaceutically acceptable salt thereof, or the like.

摘要翻译： 本发明提供式（I）表示的含氮芳香族杂环衍生物：[式中，W表示CR 3（式中，R 3表示氢原子等）等，R 4表示氢原子等，R 5表示 氢原子等，R 9表示取代的咪唑基，R 12和R 13可以相同或不同，各自表示氢原子等，R 22和R 23可以相同或不同，分别表示氢原子等，R 24 表示氢原子等，Y表示C-R25（其中R25表示氢原子等）等或其药学上可接受的盐和FGFR抑制剂，作为活性成分，含氮芳香族 杂环衍生物或其药学上可接受的盐等。

公开(公告)号：US08250932B2

公开(公告)日：2012-08-28

申请号：US12921359

申请日：2009-02-24

申请人： Mitsuo Yokohata ,  Hirozumi Nakamura ,  Tadanori Shirasawa ,  Kazuo Kubo ,  Mitsuo Namba ,  Hisashi Saito

发明人： Mitsuo Yokohata ,  Hirozumi Nakamura ,  Tadanori Shirasawa ,  Kazuo Kubo ,  Mitsuo Namba ,  Hisashi Saito

IPC分类号： G01F1/20

CPC分类号： F17D5/06 ,  G01F15/002 ,  G01F15/003 ,  G01F15/005 ,  G01F15/063 ,  G01F15/10

摘要： The present invention is intended to make it possible to set security functions as necessary depending on usage environment, etc. and to improve the security functions; a function setting section 1116 sets security function information received from the outside via a communication line as security functions regarding the user of gas. According to the set security function, in the case that the operation conditions of the security function are satisfied, a monitoring section 112 detects a problem during the use of gas and outputs a security signal to a control section 114. Based on the security signal from the monitoring section 112, the control section 114 shuts off the supply of gas in the case that a phenomenon satisfying an operation condition of the set function having been set has occurred.

摘要翻译： 本发明旨在使得可以根据使用环境等来设置必要的安全功能，并且提高安全功能; 功能设定部1116将通过通信线路从外部接收的安全功能信息设置为关于气体用户的安全功能。 根据设定的安全功能，在满足安全功能的操作条件的情况下，监视部112在使用气体时检测出问题，并向控制部114输出安全信号。根据来自 在已经设定满足设定功能的动作条件的现象的情况下，监视部112，控制部114关闭气体的供给。

公开(公告)号：US20110066387A1

公开(公告)日：2011-03-17

申请号：US12993673

申请日：2009-02-27

申请人： Tsuyoshi Honda ,  Akira Matsuda ,  Kouji Murase ,  Kenji Yasuda ,  Mitsuo Namba ,  Kazuo Kubo ,  Hisashi Saito

发明人： Tsuyoshi Honda ,  Akira Matsuda ,  Kouji Murase ,  Kenji Yasuda ,  Mitsuo Namba ,  Kazuo Kubo ,  Hisashi Saito

IPC分类号： G06F19/00

CPC分类号： F23N5/184 ,  F23N5/003 ,  F23N5/24 ,  F23N2005/185 ,  F23N2023/48 ,  F23N2023/54 ,  F23N2900/05002 ,  G01F3/22

摘要： A convention appliance monitoring apparatus handles only the amount of gas used and security information for the case of a gas cutoff and can not address social needs for a desire to obtain information about influence (e.g., an amount of CO2 emission) of use of the gas combustion appliance on a terrestrial environment.Based on a gas appliance used by a client and a gas flow signal pertaining the gas appliance which are output from an appliance determination unit 2, CO2 emission data on the gas appliance stored in a CO2 emission data storage unit 3, and CO2 emission data which are to be compared with the gas appliance and stored in a comparative CO2 emission data storage unit 4, a CO2 emission calculation unit 5 calculates an amount of CO2 emission, an comparative amount of CO2 emission and a difference between the amount of CO2 emission and the comparative amount of CO2 emission. Accordingly, it is possible to determine the amount of CO2 emission produced by using the gas appliance and the difference between the amount of CO2 emission and the comparative amount of CO2 emission.

摘要翻译： 会议用具监控装置仅处理气体使用量和安全信息，并且不能满足社会需求以获得有关使用气体的影响（例如，二氧化碳排放量）的信息 燃烧器具在陆地环境中。 基于客户使用的燃气器具和从器具判定单元2输出的与燃气器具相关的气体流量信号，存储在二氧化碳排放数据存储单元3中的燃气器具上的二氧化碳排放数据和二氧化碳排放数据， 将其与燃气用具进行比较并存储在比较二氧化碳排放数据存储单元4中，二氧化碳排放量计算单元5计算二氧化碳排放量，二氧化碳排放量的比较量和二氧化碳排放量之间的差异 比较二氧化碳排放量。 因此，可以确定使用燃气器具产生的二氧化碳排放量和二氧化碳排放量与二氧化碳排放量的比较差之间的差异。

公开(公告)号：US20110012738A1

公开(公告)日：2011-01-20

申请号：US12921104

申请日：2009-02-24

申请人： Hirozumi Nakamura ,  Mitsuo Yokohata ,  Yasuo Koba ,  Kazuo Kubo ,  Mitsuo Namba ,  Hisashi Saito

发明人： Hirozumi Nakamura ,  Mitsuo Yokohata ,  Yasuo Koba ,  Kazuo Kubo ,  Mitsuo Namba ,  Hisashi Saito

IPC分类号： G08B17/10 ,  F17D3/00

CPC分类号： G06Q10/06 ,  F23N5/184 ,  Y02P90/84 ,  Y10T137/8158

摘要： It is an object to acquire in real time information about the type of an appliance used at home, a cumulative time elapsed from installation of the appliance, and the like; preliminarily acquire inspection timing; and prevent occurrence of a problem in the appliance. There are provided an appliance determination section 13 that determines a gas appliance to be used from the quantity of momentary flow determined from a measured value of a flow measurement section 11 by predetermined arithmetic processing; an appliance setting section 43 capable of arbitrarily inputting appliance information about a monitoring target appliance; an appliance registration section 14 that registers a monitoring target appliance in accordance with a result of determination made by the appliance determination section 13 and an result of input performed with the appliance setting section 43; a timer section 16 that integrates and stores a time elapsed from a point in time when an appliance is registered as a monitoring target appliance in an appliance registration section 14 on a registered individual appliance basis; a communication section 41 that is connected to a monitoring center 40 with a communication line and that performs communication processing of flow information, appliance information, and the like; and a control section 15 that compares an integrated time of the timer section 16 with a preset monitoring time and outputs a signal for sending a report to a gas utility company or a user when the integrated time has exceeded the monitoring time.

摘要翻译： 实时获取关于在家中使用的家电类型的信息，从设备的安装过去的累积时间等; 初步获取检验时间; 并防止设备中出现问题。 提供了一种器具判定部13，其通过预定的算术处理从由流量测量部11的测量值确定的瞬时流量确定要使用的燃气器具; 能够任意地输入关于监视对象器具的器具信息的器具设定部43; 设备登记部分14，根据由设备确定部分13做出的确定结果和用设备设置部分43执行的输入结果登记监视目标设备; 定时器部分16，其以登记的个人装置为基础，将从器具在作为监视目标器具注册的时间点经过的时间整合并存储在器具登记部分14中; 通信部41，其连接到具有通信线路的监视中心40，并且执行流信息，设备信息等的通信处理; 以及控制部15，其将定时器部16的积分时间与预设的监视时间进行比较，并且当积分时间超过监视时间时，输出用于向气体公用事业公司或用户发送报告的信号。

公开(公告)号：US20110000310A1

公开(公告)日：2011-01-06

申请号：US12921359

申请日：2009-02-24

申请人： Mitsuo Yokohata ,  Hirozumi Nakamura ,  Tadanori Shirasawa ,  Kazuo Kubo ,  Mitsuo Namba ,  Hisashi Saito

发明人： Mitsuo Yokohata ,  Hirozumi Nakamura ,  Tadanori Shirasawa ,  Kazuo Kubo ,  Mitsuo Namba ,  Hisashi Saito

IPC分类号： G01F1/20 ,  G06F19/00

CPC分类号： F17D5/06 ,  G01F15/002 ,  G01F15/003 ,  G01F15/005 ,  G01F15/063 ,  G01F15/10

摘要： The present invention is intended to make it possible to set security functions as necessary depending on usage environment, etc. and to improve the security functions; a function setting section 1116 sets security function information received from the outside via a communication line as security functions regarding the user of gas. According to the set security function, in the case that the operation conditions of the security function are satisfied, a monitoring section 112 detects a problem during the use of gas and outputs a security signal to a control section 114. Based on the security signal from the monitoring section 112, the control section 114 shuts off the supply of gas in the case that a phenomenon satisfying an operation condition of the set function having been set has occurred.

摘要翻译： 本发明旨在使得可以根据使用环境等来设置必要的安全功能，并且提高安全功能; 功能设定部1116将通过通信线路从外部接收的安全功能信息设置为关于气体用户的安全功能。 根据设定的安全功能，在满足安全功能的操作条件的情况下，监视部112在使用气体时检测出问题，并向控制部114输出安全信号。根据来自 在已经设定满足设定功能的动作条件的现象的情况下，监视部112，控制部114关闭气体的供给。

公开(公告)号：US20100330515A1

公开(公告)日：2010-12-30

申请号：US12919589

申请日：2009-02-24

申请人： Kouichi Ueki ,  Kazutaka Asano ,  Tadanori Shirasawa ,  Mitsuo Yokohata ,  Hirozumi Nakamura ,  Kazuo Kubo ,  Mitsuo Namba ,  Hisashi Saito

发明人： Kouichi Ueki ,  Kazutaka Asano ,  Tadanori Shirasawa ,  Mitsuo Yokohata ,  Hirozumi Nakamura ,  Kazuo Kubo ,  Mitsuo Namba ,  Hisashi Saito

IPC分类号： F23N5/24 ,  G08B17/10

CPC分类号： G08B21/14 ,  F23N5/242 ,  F23N2900/05001

摘要： An object of the invention is to appropriately control the use limit function of an appliance according to the concentration level of CO gas. A gas shutoff device is made up of a flow rate registration unit 28 for registering as an appliance flow rate, an average flow rate found by classifying and storing in a flow rate storage unit 26 after flow rate detection, a CO gas leakage determination unit 29 for inputting an output signal responsive to the concentration level of CO gas from a CO alarm 20, an appliance estimation unit 30, when a signal is output by the CO gas leakage determination unit 29 and the flow rate is registered in the flow rate registration unit 28, for storing a flow rate pattern group stored in the flow rate storage unit 26 and the registered flow rate and estimating a CO gas leakage appliance, an appliance flow rate storage unit 31 for storing the flow rate pattern group, and a communication unit 35 for reporting appliance information.

摘要翻译： 本发明的目的是根据CO气体的浓度水平适当地控制器具的使用限制功能。 气体切断装置由流量登记单元28构成，用于将流量检测后的流量存储单元26分类存储的器具流量，通过分类存储的平均流量，CO气体泄漏判定单元29 用于输入响应于来自CO报警器20的CO气体的浓度水平的输出信号，器具估计单元30，当CO气体泄漏判定单元29输出信号时，将流量登记在流量对准单元 如图28所示，用于存储存储在流量存储单元26中的流量模式组和注册流量并估计CO气体泄漏装置，存储流量模式组的设备流量存储单元31和通信单元35 用于报告设备信息。

公开(公告)号：US20070061660A1

公开(公告)日：2007-03-15

申请号：US11304913

申请日：2005-12-16

申请人： Yoshiaki Konishi ,  Kazuo Kubo ,  Yasuyuki Endoh

发明人： Yoshiaki Konishi ,  Kazuo Kubo ,  Yasuyuki Endoh

IPC分类号： H04L1/00 ,  G08C25/00 ,  G06F11/00 ,  H03M13/00 ,  G06F11/30

CPC分类号： H04L25/497 ,  H04L27/2096

摘要： A parallel precoder circuit executes an EXOR operation on an n-row parallel input, and outputs an n-row parallel output, where 2≦n. Outputs of EXOR circuits each of which having a largest column number from among EXOR circuits disposed in first to (n−1)th rows become first-row to (n−1)th-row parallel outputs, respectively. A output of an nth-row delay circuit becomes an nth-row parallel output.

摘要翻译： 并行预编码器电路对n行并行输入执行EXOR运算，并输出n行并行输出，其中2 <= n。 分别从第一到第（n-1）行中排列的EXOR电路中具有最大列数的EXOR电路的输出分别成为第一行到第（n-1）行并行输出。 第n行延迟电路的输出变为第n行并行输出。

公开(公告)号：US20070027318A1

公开(公告)日：2007-02-01

申请号：US11526739

申请日：2006-09-26

申请人： Kazuo Kubo ,  Yasunari Fujiwara ,  Toshiyuki Isoe

发明人： Kazuo Kubo ,  Yasunari Fujiwara ,  Toshiyuki Isoe

IPC分类号： C07D413/02 ,  C07D403/02 ,  C07D401/02

CPC分类号： C07D215/233 ,  C07D231/12 ,  C07D233/56 ,  C07D239/88 ,  C07D249/08 ,  C07D401/12 ,  C07D403/12

摘要： An object of the present invention is to provide compounds which have antitumor activity and do not change cytomorphosis. Disclosed are compounds represented by formula (I) and a pharmaceutically acceptable salts and solvates thereof and pharmaceutical compositions comprising said compounds: wherein X and Z each independently represent CH or N; R1 to R3 represent H, substituted alkoxy, unsubstituted alkoxy or the like; R4 represents H; R5 to R8 represent H, halogen, alkyl, alkoxy, alkylthio, nitro, or amino, provided that R5 to R8 do not simultaneously represent H; R9 and R10 represent H, alkyl, or alkylcarbonyl; and R11 represents alkyl, alkenyl, alkynyl, or aralkyl.

摘要翻译： 本发明的目的是提供具有抗肿瘤活性并且不改变细胞毒性的化合物。 公开了由式（I）表示的化合物及其药学上可接受的盐和溶剂合物和包含所述化合物的药物组合物：其中X和Z各自独立地表示CH或N; R 1至R 3代表H，取代的烷氧基，未取代的烷氧基等; R 4表示H; R 5至R 8表示H，卤素，烷基，烷氧基，烷硫基，硝基或氨基，条件是R 5至R“ > 8 不同时代表H; R 9和R 10代表H，烷基或烷基羰基; R 11表示烷基，烯基，炔基或芳烷基。

公开(公告)号：US07043162B2

公开(公告)日：2006-05-09

申请号：US10031235

申请日：2001-05-16

申请人： Kazuo Kubo ,  Hideo Yoshida ,  Hiroshi Ichibangase

发明人： Kazuo Kubo ,  Hideo Yoshida ,  Hiroshi Ichibangase

IPC分类号： H04B10/00

CPC分类号： H03M13/29 ,  H03M13/03 ,  H03M13/15 ,  H03M13/1515 ,  H03M13/2909 ,  H04L1/0041 ,  H04L1/005 ,  H04L1/0057 ,  H04L1/0066 ,  H04L1/0071

摘要： An FEC multiplexing circuit (2) has a configuration in which a first memory circuit (15) is arranged on the input stage of a first RS encoding circuit (16), a second memory circuit (17) is arranged on the input stage of a second RS encoding circuit (18), error correction encoding is performed by a combination of different data having two directions, and thereafter, error correction codes are multiplexed to generate an FEC frame. On the other hand, an FEC demultiplexing circuit (6) has a configuration in which a third memory circuit (42) is arranged on the output stage of a first RS decoding circuit (41), a fourth memory circuit (44) is arranged on the output stage of a second RS decoding circuit (43), error correction is performed by a combination of different data having two directions, and, thereafter, parallel data read from the fourth memory circuit (44) are multiplexed to reproduce original information data.

摘要翻译： FEC复用电路（2）具有第一存储器电路（15）布置在第一RS编码电路（16）的输入级上的配置，第二存储器电路（17）布置在输入级 第二RS编码电路（18），通过具有两个方向的不同数据的组合来执行纠错编码，然后对纠错码进行多路复用以产生FEC帧。 另一方面，FEC解复用电路（6）具有第三存储电路（42）配置在第一RS解码电路（41）的输出级上的结构，第四存储电路（44）配置在 通过具有两个方向的不同数据的组合来执行第二RS解码电路（43）的输出级，然后对从第四存储器电路（44）读取的并行数据进行多路复用以再现原始信息数据。

公开(公告)号：US06870859B1

公开(公告)日：2005-03-22

申请号：US09518264

申请日：2000-03-03

申请人： Seiji Kozaki ,  Kazuo Kubo ,  Hiroshi Ichibangase ,  Eiichi Shibano ,  Tadami Yasuda

发明人： Seiji Kozaki ,  Kazuo Kubo ,  Hiroshi Ichibangase ,  Eiichi Shibano ,  Tadami Yasuda

IPC分类号： H04J3/00 ,  H04J3/04 ,  H04Q11/04

CPC分类号： H04Q11/0478 ,  H04J2203/0089

摘要： A multiplex transmission system of tributary signals multiplexes a plurality of tributary signals after adding to them frame information common to all the tributary signals and identification codes different for the individual tributary signals. This makes it possible to solve a problem of a conventional multiplex system of tributary signals in that the transmission rate is limited because it multiplexes a plurality of tributary signals with adding an SOH (section overhead) to generate an STM-N frame to be transmitted and received, which requires a considerable time.

摘要翻译： 辅助信号的多路复用传输系统在添加了多个辅助信号之后，复用多个辅助信号，所述辅助信号与所有辅助信号共同的帧信息和对于各个辅助信号不同的识别码。 这使得可以解决常规的辅助信号多路复用系统的问题在于传输速率受到限制，因为它将多个辅助信号与SOH（部分开销）相加以产生要发送的STM-N帧，并且 收到，这需要相当长的时间。