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公开(公告)号：US20160346747A1
公开(公告)日：2016-12-01
申请号：US15114697
申请日：2015-01-30
发明人： Shaun R. Devitt , Jon Suh
CPC分类号： B01F13/0023 , A61M5/19 , A61M5/284 , A61M2005/3131 , A61M2205/0222 , A61M2205/0238 , A61M2207/10 , B01F5/0082 , B01F5/048 , B01F15/0223 , B01F15/0237 , B01F2015/00116 , B05B1/14 , B05B7/0876
摘要： A treatment apparatus for a mixing device having a concentric barrel configuration. The treatment apparatus includes a manifold including an input end and an output end. The treatment apparatus also includes a conduit body having a manifold end and a nozzle end. The manifold end is connected to the output end of the manifold, and the conduit body includes at least one nozzle at the nozzle end of the conduit body opposite the manifold. At least one fluid pathway is formed between the input end of the manifold, the conduit body, and the at least one nozzle,
摘要翻译： 一种用于具有同心桶构造的混合装置的处理装置。 治疗装置包括具有输入端和输出端的歧管。 处理装置还包括具有歧管端部和喷嘴端部的导管本体。 歧管端部连接到歧管的输出端，导管主体包括至少一个喷嘴，其位于导管主体的与歧管相对的喷嘴端处。 在歧管的输入端，导管主体和至少一个喷嘴之间形成至少一个流体路径，
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公开(公告)号：US20160279344A1
公开(公告)日：2016-09-29
申请号：US14777713
申请日：2014-03-27
IPC分类号： A61M5/32
CPC分类号： A61M5/3221 , A61M5/322 , A61M5/508 , A61M2005/3231 , A61M2207/00
摘要： Needle assemblies for retractable needle syringes include a needle, a needle seal, and a needle retainer, wherein the needle includes one or more barbs substantially at its proximal end. The needle retainer engages an optional needle-over-mold component that is fixedly attached to the needle. The needle-over-mold may be connected to the distal surface of the needle seal and may travel, such as by being a couple component, with the needle during the operation of the syringe. A safety syringe includes a barrel having a needle assembly mounted at a distal end and a plunger assembly mounted at a proximal end. A drug may be contained in a drug chamber of barrel, between the plunger assembly and needle assembly, proximally of the needle seal for drug delivery to a user. The plunger assembly includes a plunger seal having a needle-engaging portion to capture the needle at the barb for retraction.
摘要翻译： 用于可缩回针式注射器的针组件包括针，针密封件和针保持器，其中针基本上在其近端处包括一个或多个倒钩。 针保持器接合固定地附接到针的可选的针模组件。 针式模具可以连接到针状密封件的远端表面，并且可以在注射器的操作期间例如通过作为联接部件与针一起行进。 安全注射器包括具有安装在远端的针组件的柱体和安装在近端的柱塞组件。 药物可以容纳在枪管的药物室中，位于柱塞组件和针组件之间，针头密封件的近侧用于药物递送给使用者。 柱塞组件包括具有针接合部分的柱塞密封件，以在针倒钩处捕获针头以用于收回。
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公开(公告)号：US20150297827A1
公开(公告)日：2015-10-22
申请号：US14423599
申请日：2013-08-29
发明人： Ian B. HANSON , Scott BEAVER , Paul F. BENTE, IV , Kevin BOKELMAN , Mark MAJETTE
CPC分类号： A61M5/1454 , A61M5/1452 , A61M5/14546 , A61M5/14566 , A61M5/16804 , A61M2005/14208 , A61M2202/0007 , A61M2205/3334
摘要： A controlled delivery drive mechanism includes a drug container having a barrel and a plunger seal; a drive housing within which at least initially partially resides a piston having an interface surface and a drive rack; and a power spring. The piston is configured to contact and axially translate the plunger seal within barrel. The mechanism may be configured to convert rotational movement of a drive pinion to axial translation of the drive rack, or to convert axial force of a linear power spring into torsional motion of a drive pinion. A regulating mechanism meters the drive pinion such that the piston is axially translated at a controlled rate. The drug container may contain a drug fluid within a drug chamber for drug delivery at a controlled rate. The regulating mechanism may be an escapement regulating mechanism. A drug delivery pump includes such controlled delivery drive mechanisms.
摘要翻译： 受控传送驱动机构包括具有筒体和柱塞密封件的药物容器; 驱动器壳体，其中至少最初部分地驻留有具有界面表面的活塞和驱动齿条; 和动力弹簧。 活塞构造成使柱塞密封件在筒内接触并轴向平移。 该机构可以被配置为将驱动小齿轮的旋转运动转换成驱动齿条的轴向平移，或者将线性动力弹簧的轴向力转换成驱动小齿轮的扭转运动。 调节机构计量驱动小齿轮，使得活塞以受控的速度轴向平移。 药物容器可以在药物室内含有药物流体，用于以受控的速率进行药物递送。 调节机构可以是擒纵机构。 药物输送泵包括这种受控输送驱动机构。
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公开(公告)号：US20150265500A1
公开(公告)日：2015-09-24
申请号：US14436389
申请日：2013-12-05
发明人： Robert Scott Russo , Jeffrey M. Johnson , Christopher C. Rafferty , Tod H. Brenner , Gautam N. Shetty
CPC分类号： A61J1/2096 , A61J1/201 , A61J1/2055 , A61J1/2065 , A61M5/322 , A61M39/10 , A61M2039/1044 , A61M2039/1077 , A61M2207/00
摘要： A vial adapter is provided for interconnecting a vial having a closure and a fluid delivery device such as a safety syringe. The vial adapter comprises an adapter housing having a base, a shroud extending or projecting from the base and a cannula extending or projecting from the base for penetrating a rubber seal on the vial closure to thereby establish fluid communication between the vial and the vial adapter. The shroud may comprise a plurality of latitudinal slits or windows within each of which resides a flexion arm connected to the shroud, each flexion arm capable of engaging and/or retaining vial closures of any of a variety of different sizes. The vial adapter may comprise a conduit tip in fluid communication with the cannula to allow transfer of fluid to or from the safety syringe while also preventing inadvertent activation of a safety syringe needle retraction mechanism.
摘要翻译： 提供小瓶适配器用于将具有封闭件的瓶和诸如安全注射器之类的流体输送装置相互连接。 小瓶适配器包括适配器壳体，其具有底座，从底座延伸或突出的护罩以及从底座延伸或伸出的套管，用于穿过小瓶盖上的橡胶密封件，从而在小瓶和小瓶适配器之间建立流体连通。 护罩可以包括多个横向狭缝或窗户，每个纬纱狭缝或窗口都位于连接到护罩的屈曲臂，每个弯曲臂能够接合和/或保持各种不同尺寸的任何一个的瓶盖。 小瓶适配器可以包括与插管流体连通的导管尖端，以允许将流体传送到安全注射器或从安全注射器传输流体，同时还防止安全注射器针回缩机构的无意激活。
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55.发明申请RETRACTABLE SYRINGE WITH IMPROVED DELIVERY EFFICIENCY AND LOCKING SYSTEM 审中-公开具有改进的交付效率和锁定系统的可回收的发送器公开(公告)号：US20150141936A1
公开(公告)日：2015-05-21
申请号：US14577262
申请日：2014-12-19
发明人： Craig Stephen Thorley , Joseph Hermes Kaal , Richard Sokolov , Ernesto Hueso , Huw Wallis , Scott Chad , Christopher Dunn
CPC分类号： A61M5/322 , A61M5/31511 , A61M5/3234 , A61M5/50 , A61M2005/323 , A61M2005/3231 , A61M2205/19 , A61M2207/00 , B32B37/142 , B32B37/18 , Y10T29/49826
摘要： A plunger, a needle assembly and a retractable syringe comprising same are provided. The plunger comprises a plunger member and a plunger outer having a lock spring that prevents or impedes movement of the plunger member after needle retraction. The plunger further comprises another locking member for engaging the barrel to prevent or impede further movement of the plunger outer after delivery of fluid contents. The plunger member has a plunger seal which engages a retractable needle of the needle assembly for retraction. The retractable needle comprises a cannula and needle body with a plurality of fluid channels that co-operate with a fluid conduit of the plunger seal to efficiently direct fluid to the cannula. A needle retainer comprises a plurality of barbed arms releasably coupled to the needle body, whereby an ejector with tabs facilitates release of the retractable needle from the needle retainer to allow compressed spring-driven retraction.
摘要翻译： 提供了柱塞，针组件和包括其的可缩回注射器。 柱塞包括柱塞构件和具有锁定弹簧的柱塞外部，其在针回缩之后防止或阻止柱塞构件的移动。 柱塞还包括用于接合筒体的另一个锁定构件，以防止或妨碍在输送流体内容物之后柱塞外部的进一步移动。 柱塞构件具有柱塞密封件，其接合针组件的可缩回针以缩回。 可伸缩针包括插管和针体，其具有与柱塞密封件的流体导管配合的多个流体通道，以有效地将流体引导到套管。 针保持器包括可释放地联接到针体的多个倒钩臂，由此具有翼片的推出器有助于将可缩回针从针保持器释放以允许压缩的弹簧驱动缩回。
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56.发明申请公开(公告)号：US20150141920A1
公开(公告)日：2015-05-21
申请号：US14605287
申请日：2015-01-26
CPC分类号： A61M5/172 , A61M5/1452 , A61M5/14566 , A61M2005/14506 , A61M2205/58
摘要： A drive mechanism having integrated status indication includes a drive housing, a status switch interconnect, a drive biasing member, a piston, and a drug container having a cap, a pierceable seal, a barrel, and a plunger seal, wherein the drive biasing member is configured to bear upon an interface surface of the piston. Drive mechanism may include an incremental status stem having a stem interconnect, wherein the stem resides within the drive housing and the piston, and wherein the stem has an interconnect which engages one or more contacts on the piston to provide incremental feedback. A drug delivery pump with integrated status indication includes a housing and an assembly platform, upon which an activation mechanism, an insertion mechanism, a fluid pathway connection, a power and control system, and the drive mechanism having a drug container may be mounted.
摘要翻译： 具有集成状态指示的驱动机构包括驱动器壳体，状态开关互连件，驱动偏压构件，活塞以及具有盖帽，可刺破密封件，筒体和柱塞密封件的药物容器，其中驱动偏置构件 构造成承载在活塞的界面表面上。 驱动机构可以包括具有杆互连的增量状态杆，其中杆位于驱动壳体和活塞内，并且其中杆具有与活塞上的一个或多个触点接合以提供增量反馈的互连。 具有集成状态指示的药物输送泵包括壳体和组装平台，可以安装激活机构，插入机构，流体通路连接，动力和控制系统以及具有药物容器的驱动机构。
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公开(公告)号：US20150025454A1
公开(公告)日：2015-01-22
申请号：US14333442
申请日：2014-07-16
发明人： Lance W. Wetzel , Gautam N. Shetty , Lou Castagna
CPC分类号： A61M5/2448 , A61M5/31525 , A61M5/31533 , A61M5/31535 , A61M5/31578 , A61M5/31591 , A61M5/31596 , A61M5/322 , A61M5/3234 , A61M2005/2451 , A61M2005/3128
摘要： Mixing syringes including a valve mechanism are configured and configurable to enable one or more substances to be prefilled into the syringe. The valve mechanism may be an aspect of a distal seal assembly. Actuation of the valve mechanism permits opening of a fluid passage for the mixing of one or more substances, and the resulting mixed substance can be delivered by the syringe, for example, for administration of a pharmaceutical to a subject.
摘要翻译： 包括阀机构的混合注射器被配置和配置为使得一种或多种物质能够预填充到注射器中。 阀机构可以是远端密封组件的一个方面。 阀机构的致动允许打开用于混合一种或多种物质的流体通道，并且所得到的混合物质可以通过注射器输送，例如用于向受试者施用药物。
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58.发明申请公开(公告)号：US20140200510A1
公开(公告)日：2014-07-17
申请号：US14163690
申请日：2014-01-24
发明人： Ryan M. Agard , Ian B. Hanson , Nicholas J. Ciccarelli , Sean M. O'Connor , Kevin Bokelman , Paul F. Bente, IV
CPC分类号： A61M5/14566 , A61M5/172 , A61M5/3157 , A61M2005/14252 , A61M2205/33 , A61M2205/50 , A61M2205/58 , A61M2205/82
摘要： A drive mechanism includes a housing, a piston adapted to impart movement to a plunger seal within a drug container, a plurality of biasing members disposed in parallel, and a retainer. The biasing members are disposed to release energy to cause movement of the piston from a retracted first position to the extended second position, the piston bearing against the plunger seal to dispense medicine. The retainer is disposed to maintain the biasing members in the energized position and to release the biasing members to permit the piston to dispense the medicine. The drive mechanism may also include an end-of-dose indicator to identify at least one of when the sleeve assembly is disposed subjacent a window in the housing, the relative motion of the sleeve assembly with reference to the window or another reference component, the stoppage of such motion, and the rated or change of rate of motion.
摘要翻译： 驱动机构包括壳体，活塞，适于使药物容器内的柱塞密封件移动，平行设置的多个偏置构件和保持器。 偏置构件设置成释放能量以使活塞从缩回的第一位置移动到延伸的第二位置，活塞抵靠柱塞密封件分配药物。 保持器被设置成将偏置构件保持在通电位置并且释放偏压构件以允许活塞分配药物。 驱动机构还可以包括剂量末端指示器，用于识别当套筒组件布置在壳体内的窗口下方时的至少一个，套筒组件相对于窗口或另一个参考部件的相对运动， 停止此类动作，以及运动速度的额定值或变化。
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59.发明申请公开(公告)号：US20140012229A1
公开(公告)日：2014-01-09
申请号：US13934958
申请日：2013-07-03
发明人： Kevin Bokelman , George M. Wohlhieter , Thomas F. McGee , Arthur G. Marlin , Stefanie A. Hurowitz , David R. Jansen , Ellen Ni Chathail
IPC分类号： A61M5/20
CPC分类号： A61M5/2033 , A61M5/20 , A61M5/24 , A61M5/31513 , A61M5/31515 , A61M5/31581 , A61M2205/502
摘要： An automatic injector includes a housing having a guide, a drive control mechanism, a transmission assembly, a motor, and an energy source. The housing may further include a cartridge cover. A drive control mechanism includes a drive screw, a cartridge carrier, a plunger carrier, and one or more control transfer instruments, such as a puck or cylinder. The drive screw interfaces and connects with the plunger carrier. The automatic injector is configured to accept a variety of syringes as cartridges for drug delivery. The cartridges may be ejected from the injector and safely disposed after use, making the injector a reusable automatic injector. The reusable automatic injector may further include one or more sensors, such as a cartridge sensor and a patient sensor. The novel incorporation of the drive control mechanisms into the automatic injectors of the present invention enables a single motor and transmission assembly to drive the function of multiple components, which may include the steps of: preparation and alignment of a cartridge for injection, removal of a safety cap or needle shield, needle injection, drug dose delivery, and syringe and/or needle retraction. Methods of manufacture and methods of use are also disclosed.
摘要翻译： 自动注射器包括具有引导件的壳体，驱动控制机构，变速器组件，马达和能量源。 壳体还可以包括盒盖。 驱动控制机构包括驱动螺杆，筒式载体，柱塞架，以及一个或多个控制转移装置，例如圆盘或圆筒。 驱动螺丝接口并与柱塞支架连接。 自动注射器被配置为接受各种注射器作为用于药物递送的药筒。 墨盒可以从喷射器喷射并在使用后安全地放置，使喷射器成为可重复使用的自动喷射器。 可重复使用的自动注射器还可以包括一个或多个传感器，例如筒传感器和患者传感器。 驱动控制机构在本发明的自动喷射器中的新颖结合使得单个电动机和变速器组件能够驱动多个部件的功能，其可以包括以下步骤：准备和对准用于注射的药筒， 安全帽或针罩，针注射，药物剂量递送，注射器和/或针回缩。 还公开了制造方法和使用方法。
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公开(公告)号：US20130338602A1
公开(公告)日：2013-12-19
申请号：US13688386
申请日：2012-11-29
发明人： Craig Stephen Thorley , Joseph Hermes Kaal , Chris Rafferty , Richard Sokolov , Ernesto Hueso , Huw Wallis , Steve Chi Truong
IPC分类号： A61M5/32
CPC分类号： A61M5/3232 , A61M5/31511 , A61M5/3202 , A61M5/3234 , A61M5/345 , A61M2005/3103 , A61M2005/323 , A61M2005/3231 , A61M2005/3238 , A61M2005/5073 , A61M2205/581 , A61M2205/582 , Y10T29/49826
摘要： A retractable syringe, plunger and releasable needle assembly including a retractable needle, a needle seal, a retaining member and an ejector member. The retaining member has a mating surface for mounting to a complementary mating surface of an interior wall of a syringe barrel. The plunger comprises a plunger outer, a plunger rod frangibly connected to a controlling member, a spring and a unitary plunger seal capable of engaging the retractable needle, wherein the plunger rod, plunger outer and the controlling member co-operate to releasably maintain the spring in an initially compressed state. After delivery of fluid contents of the syringe, the plunger forces the ejector member to release the retractable needle from the retaining member. Decompression of the spring at the end of depression of the plunger facilitates retraction of the retractable needle when engaged with the unitary plunger seal.
摘要翻译： 可伸缩的注射器，柱塞和可释放的针组件，其包括可缩回的针，针密封件，保持构件和顶出件。 保持构件具有用于安装到注射器筒的内壁的互补配合表面的配合表面。 柱塞包括柱塞外部，易于连接到控制构件的柱塞杆，弹簧和能够接合可缩回针的单一柱塞密封件，其中柱塞杆，柱塞外部和控制构件协作以可释放地保持弹簧 处于初始压缩状态。 在输送注射器的流体内容物之后，柱塞迫使顶出部件从保持件释放可伸缩的针。 在柱塞压下结束时，弹簧的减压有助于可缩回针在与单一柱塞密封件接合时的缩回。
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