公开(公告)号：US20190136125A1

公开(公告)日：2019-05-09

申请号：US16240490

申请日：2019-01-04

申请人： Canon Kabushiki Kaisha

发明人： Kenji Yamada ,  Satoshi Igawa ,  Wataru Kubo ,  Yuto Ito ,  Isao Kawata

IPC分类号： C09K9/02 ,  G02F1/155 ,  E06B9/24 ,  E06B3/67 ,  C07D241/46

摘要： An organic compound represented by the following general formula is provided. In the above formula (1), R11 to R15 each independently represent a hydrogen atom, an alkyl group, an alkoxy group, an aryl group, an aryloxy group, an aralkyl group, an acyl group, or a halogen atom provided that at least one of R11, R13, and R15 represents the alkoxy group or the aryloxy group; and R11 to R15 may form a ring structure therebetween. R5 and R6 each independently represent an alkyl group, an aryl group, or an aralkyl group. In addition, R21 to R24 each independently represent a hydrogen atom, an alkyl group, an alkoxy group, an aryl group, an aryloxy group, an aralkyl group, an acyl group, or a halogen atom and may form a ring structure therebetween. The above groups except the acyl group may be substituted when necessary.

公开(公告)号：US20180312473A1

公开(公告)日：2018-11-01

申请号：US15744319

申请日：2016-07-15

申请人： Robert William Huigens, III

发明人： Robert William Huigens, III

IPC分类号： C07D241/46 ,  C07D241/38 ,  A61P31/04

CPC分类号： C07D241/46 ,  A01N43/60 ,  A61K8/494 ,  A61K31/185 ,  A61K31/47 ,  A61K31/498 ,  A61K45/06 ,  A61Q17/005 ,  C07D241/36 ,  C07D241/42 ,  A61K2300/00

摘要： The present invention provides novel phenazine derivatives, such as compounds of Formula (I′) (e.g., Formula (I)), (II), and (III), and pharmaceutically acceptable salts thereof. The compounds of the invention are expected to be antimicrobial agents and may act by a microbial warfare strategy (e.g., a reactive oxygen species (ROS)-based competition strategy). The present invention also provides pharmaceutical compositions, kits, uses, and methods that involve the compounds of the invention and may be useful in preventing or treating a microbial infection (e.g., a bacterial infection or mycobacterial infection) in a subject, inhibiting the mycobacterium), inhibiting the formation and/or growth of a biofilm, reducing or clearing a biofilm, and/or disinfecting a surface.

公开(公告)号：US09745273B2

公开(公告)日：2017-08-29

申请号：US15032778

申请日：2014-11-03

申请人： Universitetet I Oslo ,  Bergen Teknologioverføring AS ,  Université Claude Bernard Lyon 1

发明人： Stein Ove Døskeland ,  Pål Rongved ,  Lars Herfindal ,  Marc Le Borgne ,  Elvar Örn Viktorsson ,  Ove Alexander Høgmoen Åstrand

IPC分类号： C07D241/46 ,  C07D403/12 ,  C07D403/14 ,  C07D241/52 ,  C07D405/14 ,  A61K47/48 ,  C07F9/6509 ,  C07D405/12 ,  C08G73/02 ,  C08B37/16 ,  A61K31/498

CPC分类号： C07D241/52 ,  A61K31/498 ,  A61K47/6951 ,  C07D405/12 ,  C07D405/14 ,  C07F9/650994 ,  C08B37/0012 ,  C08G73/0273

摘要： Novel phenazine derivatives, methods for their preparation and their medical use, in particular as anti-neoplastic agents and anti-infective agents, are provided. Novel methods for the preparation of iodinin and myxin are also provided.

公开(公告)号：US09741969B2

公开(公告)日：2017-08-22

申请号：US14860559

申请日：2015-09-21

申请人： NATIONAL TSING HUA UNIVERSITY

发明人： Chien-Hong Cheng ,  Wei-Ting Hsieh ,  Chen-Hsun Hung ,  Min-Jie Huang ,  Cheng-Chang Lai ,  Chuang-Yi Liao

IPC分类号： H01L51/54 ,  H01L51/52 ,  C07D241/46 ,  C07D241/44 ,  C07D487/04 ,  C07D241/42 ,  H01L51/00

CPC分类号： H01L51/5278 ,  C07D241/42 ,  C07D241/44 ,  C07D241/46 ,  C07D487/04 ,  H01L51/0051 ,  H01L51/0072

摘要： A carrier generation material is provided, which has a chemical structure of: wherein R1 is hydrogen or alkyl group; each of R2 is independently hydrogen, halogen, —CN, —CF3, —NO2, or alkyl group; each of R3 is independently hydrogen, halogen, —CN, —CF3, —NO2, or alkyl group; R4 is hydrogen, halogen, —CN, —CF3, —NO2, or alkyl group; R5 is hydrogen, halogen, —CN, —CF3, —NO2, or alkyl group; R6 is ═O, ═NH, or malononitrile group, and R7 is hydrogen, halogen, —CN, —CF3, —NO2, or alkyl group.

公开(公告)号：US20170146880A1

公开(公告)日：2017-05-25

申请号：US15065808

申请日：2016-03-09

申请人： Gentex Corporation

发明人： Kelvin L. BAUMANN ,  Rongguang LIN ,  Punam GIRI ,  Sue FRANZ

IPC分类号： G02F1/15 ,  C07D213/04 ,  C07D213/22 ,  C07D241/46

CPC分类号： G02F1/15 ,  C07D213/04 ,  C07D213/22 ,  C07D241/46 ,  C09K9/02 ,  C09K11/06 ,  C09K2211/1029 ,  G02F2001/1512 ,  G02F2001/1515

摘要： Protic-soluble electrochromic materials, ion-paired electrochromic materials including protic-soluble electrochromic materials, as well as electrochromic media and electrochromic devices incorporating such materials, are provided. The use of protic solvent mixtures, especially mixtures incorporating water, allows for the use of a wider variety of substrate materials. For example, plastics that may be soluble in organic aprotic solvent systems may be used in water-based devices.

公开(公告)号：US09604941B2

公开(公告)日：2017-03-28

申请号：US14763830

申请日：2015-05-22

申请人： Shenzhen China Star Optoelectronics Technology Co., Ltd.

发明人： Xianjie Li ,  Yuanchun Wu ,  Shijian Su ,  Kunkun Liu ,  Ming Liu

IPC分类号： H01L21/00 ,  C07D241/46 ,  C09K11/06 ,  C07C315/04 ,  C07C317/14 ,  C07D213/34 ,  H01L51/00 ,  C07D209/86 ,  C07C317/36 ,  C07D219/02 ,  C07D265/38 ,  C07D279/22 ,  H01L51/50

CPC分类号： C07D241/46 ,  C07C315/04 ,  C07C317/14 ,  C07C317/36 ,  C07D209/86 ,  C07D213/34 ,  C07D219/02 ,  C07D265/38 ,  C07D279/22 ,  C09K11/06 ,  C09K2211/1007 ,  C09K2211/1014 ,  C09K2211/1022 ,  C09K2211/1029 ,  C09K2211/1033 ,  C09K2211/1037 ,  C09K2211/1044 ,  H01L51/0059 ,  H01L51/0067 ,  H01L51/0071 ,  H01L51/0072 ,  H01L51/5012 ,  H05B33/14 ,  H05B33/20

摘要： The invention provides a conjugated compound containing a bis(phenylsulfonyl)benzene structure, a preparation method and an application thereof, the compound includes a chemical structure with one of structural general formulas as follows: the invention obtains a conjugated compound containing a bis(phenylsulfonyl)benzene structure by selecting multiple kinds of conjugated aromatic units to react with halogen-substituted bis(phenylsulfonyl)benzene in the manner of Suzuki coupling reaction, Buchwald-Hartwig coupling reaction or copper-catalyzed halogenated aromatic amination reaction. The novel compound prepared by the invention has the characteristic of fluorescence as well as a certain electrical conductivity, and thus can be applied to fabricate a light-emitting layer or an electron transport layer of an organic electroluminescent diode.

公开(公告)号：US20160355487A1

公开(公告)日：2016-12-08

申请号：US15107531

申请日：2014-12-23

申请人： UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.

发明人： Robert William Huigens, III ,  Shouguang Jin

IPC分类号： C07D241/46 ,  C07D405/12 ,  C07D409/12 ,  A61K31/498

CPC分类号： C07D241/46 ,  A61K31/498 ,  A61K45/06 ,  C07D241/38 ,  C07D405/12 ,  C07D409/12 ,  A61K2300/00

摘要： The present invention provides novel phenazine derivatives, such as compounds of Formula (I) and (II), and pharmaceutically acceptable salts thereof. The compounds of the invention are expected to be antimicrobial agents and may act by a microbial warfare strategy (e.g., a reactive oxygen species (ROS)-based competition strategy). The present invention also provides pharmaceutical compositions, kits, uses, and methods that involve the compounds of the invention and may be useful in preventing or treating a microbial infection (e.g., a bacterial infection) in a subject, inhibiting the growth and/or reproduction of a microorganism (e.g., a bacterium), killing a microorganism (e.g., a bacterium), inhibiting the formation and/or growth of a biofilm, or reducing or clearing a biofilm.

摘要翻译： 本发明提供新的吩嗪衍生物，例如式（I）和（II）的化合物及其药学上可接受的盐。 预期本发明的化合物是抗微生物剂，并且可以通过微生物战争策略（例如，基于活性氧（ROS）的竞争策略）来起作用。 本发明还提供涉及本发明化合物的药物组合物，试剂盒，用途和方法，并且可用于预防或治疗受试者中的微生物感染（例如细菌感染），抑制生长和/或繁殖 的微生物（例如细菌），杀死微生物（例如细菌），抑制生物膜的形成和/或生长，或减少或清除生物膜。

公开(公告)号：US20160322567A1

公开(公告)日：2016-11-03

申请号：US14763830

申请日：2015-05-22

申请人： Shenzhen China Star Optoelectronics Technology Co. Ltd.

发明人： Xianjie Li ,  Yuanchun Wu ,  Shijian Su ,  Kunkun Liu ,  Ming Liu

IPC分类号： H01L51/00 ,  C07C315/04 ,  C07C317/14 ,  C07D213/34 ,  C07D241/46 ,  C07C317/36 ,  C07D219/02 ,  C07D265/38 ,  C07D279/22 ,  C09K11/06 ,  C07D209/86

CPC分类号： C07D241/46 ,  C07C315/04 ,  C07C317/14 ,  C07C317/36 ,  C07D209/86 ,  C07D213/34 ,  C07D219/02 ,  C07D265/38 ,  C07D279/22 ,  C09K11/06 ,  C09K2211/1007 ,  C09K2211/1014 ,  C09K2211/1022 ,  C09K2211/1029 ,  C09K2211/1033 ,  C09K2211/1037 ,  C09K2211/1044 ,  H01L51/0059 ,  H01L51/0067 ,  H01L51/0071 ,  H01L51/0072 ,  H01L51/5012 ,  H05B33/14 ,  H05B33/20

摘要： The invention provides a conjugated compound containing a bis(phenylsulfonyl)benzene structure, a preparation method and an application thereof, the compound includes a chemical structure with one of structural general formulas as follows: the invention obtains a conjugated compound containing a bis(phenylsulfonyl)benzene structure by selecting multiple kinds of conjugated aromatic units to react with halogen-substituted bis(phenylsulfonyl)benzene in the manner of Suzuki coupling reaction, Buchwald-Hartwig coupling reaction or copper-catalyzed halogenated aromatic amination reaction. The novel compound prepared by the invention has the characteristic of fluorescence as well as a certain electrical conductivity, and thus can be applied to fabricate a light-emitting layer or an electron transport layer of an organic electroluminescent diode.

摘要翻译： 含有二苯基砜苯基结构的共轭化合物，其制备方法，以及用于制造有机电致发光二极管的发光层或电子透射层的用途。 该化合物具有以下通式之一的化学结构：式A，式B。 在本发明中，选择多种共轭芳族单元和卤素取代的二苯砜苯基，进行Suzuki偶联，Buchwald-Hartwig偶联或铜催化卤代芳烃胺化反应，得到含有二苯基砜苯基结构的共轭化合物。 通过本发明制备的新型化合物具有荧光和一定的导电性，因此可用于制造有机电致发光二极管的发光层或电子透射层。

公开(公告)号：US08987446B2

公开(公告)日：2015-03-24

申请号：US13515710

申请日：2010-12-09

申请人： Christoph Gürtler ,  Thomas Ernst Müller ,  Pieter Ooms ,  Johann Rechner ,  Friedhelm Risse ,  Angelina Prokofieva ,  Franco Doro ,  Burkhard Köhler ,  Walter Leitner ,  Aurel Wolf

发明人： Christoph Gürtler ,  Thomas Ernst Müller ,  Pieter Ooms ,  Johann Rechner ,  Friedhelm Risse ,  Angelina Prokofieva ,  Franco Doro ,  Burkhard Köhler ,  Walter Leitner ,  Aurel Wolf

IPC分类号： C07D241/46 ,  C07F15/00 ,  C07C68/00

CPC分类号： C07F15/0066 ,  C07C68/005 ,  C07C69/96

摘要： The invention relates to bimetallic complexes in which the ligand contains a salophen unit which complexes copper, manganese or cobalt and a phenanthroline unit which complexes palladium and the two systems are linked by a continuous conjugated system. The invention further relates to the use of these bimetallic complexes as catalysts for the oxidative carbonylation of aromatic hydroxy compounds to form diaryl carbonates, a process for preparing diaryl carbonates using the bimetallic complex as catalyst and also diaryl carbonates prepared by oxidative carbonylation of aromatic hydroxy compounds using the bimetallic complexes of the invention as catalysts.

摘要翻译： 本发明涉及双金属络合物，其中配体包含络合铜，锰或钴的盐酸单体和络合钯并且两种体系通过连续共轭体系连接的菲咯啉单元。 本发明还涉及这些双金属络合物作为用于芳族羟基化合物的氧化羰基化以形成碳酸二芳基酯的催化剂的使用，使用双金属络合物作为催化剂制备碳酸二芳基酯的方法，以及通过芳族羟基化合物的氧化羰基化制备的碳酸二芳基酯 使用本发明的双金属络合物作为催化剂。

公开(公告)号：US08975256B2

公开(公告)日：2015-03-10

申请号：US13937447

申请日：2013-07-09

申请人： Santen Pharmaceutical Co., Ltd.

发明人： Mamoru Matsuda ,  Toshiyuki Mori ,  Kenji Kawashima ,  Minoru Yamamoto ,  Masatomo Kato ,  Miwa Takai ,  Masato Nagatsuka ,  Sachiko Kobayashi

IPC分类号： A61K31/535 ,  A61K31/44 ,  A01N43/40 ,  C07D241/46 ,  C07D241/44 ,  C07D401/12 ,  C07D401/14 ,  C07D405/12 ,  C07D409/12 ,  C07D409/14 ,  C07D413/12 ,  C07D417/12 ,  C07D417/14

CPC分类号： C07D241/46 ,  C07D241/44 ,  C07D401/12 ,  C07D401/14 ,  C07D405/12 ,  C07D409/12 ,  C07D409/14 ,  C07D413/12 ,  C07D417/12 ,  C07D417/14

摘要： A 1,2,3,4-tetrahydroquinoxaline compound represented by the following formula: In the formula (1), R1 represents substituents such as a halogen, an alkyl, a cycloalkyl, an aryl or a heterocyclic group; p represents 0 to 5; R2 represents substituents such as a halogen, an alkyl, a hydroxyl or an alkoxy group; q represents 0 to 2; R3 represents substituents such as hydrogen, an alkyl, an alkenyl, an alkylcarbonyl or an arylcarbonyl group; R4 and R5 independently represent substituents such as hydrogen, a halogen, an alkyl, an alkenyl, an alkynyl, a cycloalkyl, an aryl or a heterocyclic group; R6 represents substituents such as hydrogen, an alkyl, an alkenyl, an alkynyl, a cycloalkyl, an aryl or a heterocyclic group; A represents an alkylene; R7 represents OR8, NR8R9, SR8, S(O)R8, S(O)2R8; R8 and R9 independently represent substituents such as hydrogen, an alkyl or an alkenyl; and X represents O or S.

摘要翻译： 由下式表示的1,2,3,4-四氢喹喔啉化合物：式（1）中，R 1表示卤素，烷基，环烷基，芳基或杂环基等取代基。 p表示0〜5; R 2表示取代基，例如卤素，烷基，羟基或烷氧基; q表示0〜2; R3表示取代基，例如氢，烷基，烯基，烷基羰基或芳基羰基; R4和R5独立地表示取代基，例如氢，卤素，烷基，烯基，炔基，环烷基，芳基或杂环基; R6表示取代基，例如氢，烷基，烯基，炔基，环烷基，芳基或杂环基; A表示亚烷基; R 7表示OR 8，NR 8 R 9，SR 8，S（O）R 8，S（O） R8和R9独立地表示取代基，例如氢，烷基或烯基; X表示O或S.