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41.
公开(公告)号:US11710569B2
公开(公告)日:2023-07-25
申请号:US16500207
申请日:2018-03-05
Applicant: KONINKLIJKE PHILIPS N.V.
Inventor: Michael Grass , Sven Prevrhal
IPC: G06K9/00 , G16H50/30 , G06T7/12 , G16H50/50 , G16H30/20 , G16H50/20 , G16H30/40 , G06N20/00 , A61B5/319 , A61B5/346 , A61B5/026 , G06T7/00 , A61B5/364 , G16H50/70 , A61B6/00
CPC classification number: G16H50/30 , A61B5/026 , A61B5/319 , A61B5/346 , A61B5/364 , G06N20/00 , G06T7/0012 , G06T7/12 , G16H30/20 , G16H30/40 , G16H50/20 , G16H50/50 , A61B6/507 , A61B6/5217 , G06T2207/30048 , G06T2207/30101 , G16H50/70
Abstract: A computing system (118) includes a computer readable storage medium (122) with computer executable instructions (124), including a biophysical simulator (126) and an electrocardiogram signal analyzer (128). The computing system further includes a processor (120) configured to execute the electrocardiogram signal analyzer determine myocardial infarction characteristics from an input electrocardiogram and to execute the biophysical simulator to simulate a fractional flow reserve or an instant wave-free ratio index from input cardiac image data and the determined myocardial infarction characteristics.
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公开(公告)号:US11678855B2
公开(公告)日:2023-06-20
申请号:US16645224
申请日:2018-09-06
Applicant: KONINKLIJKE PHILIPS N.V.
Inventor: Christian Haase , Michael Grass , Martijn Anne Van Lavieren
CPC classification number: A61B6/5247 , A61B5/0215 , A61B6/461 , A61B6/504 , A61B6/507 , A61B6/5217 , G16H30/20 , G16H30/40 , G16H50/20 , G16H50/30 , G16H50/50 , A61B5/055 , A61B6/481
Abstract: An apparatus for analyzing coronary vessels and a corresponding method are provided in which simulated pullback data obtained from (non-invasively) acquired diagnostic images is co-registered with invasively acquired intravascular pullback data and the co-registration is used to identify disparities in the pullback data obtained using the two modalities. These disparities allow for deriving further information about the vessel geometry and/or the blood flow through the vessel. They may therefore be used to improve the physiological model.
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公开(公告)号:US11490867B2
公开(公告)日:2022-11-08
申请号:US16922069
申请日:2020-07-07
Applicant: KONINKLIJKE PHILIPS N.V.
Inventor: Hanno Heyke Homann , Michael Grass , Raoul Florent , Holger Schmitt , Odile Bonnefous , Hannes Nickisch
Abstract: The present invention relates to a device (1) for fractional flow reserve determination. The device (1) comprises a model generator (10) configured to generate a three-dimensional model (3DM) of a portion of an imaged vascular vessel tree (VVT) surrounding a stenosed vessel segment (SVS), based on a partial segmentation of the imaged vascular vessel tree (VVT). Further, the device comprises an image processor (20) configured to calculate a blood flow (Q) through the stenosed vessel segment (SVS) based on an analysis of a time-series of X-ray images of the vascular vessel tree (VVT). Still further, the device comprises a fractional-flow-reserve determiner (30) configured to determine a fractional flow reserve (FFR) based on the three-dimensional model (3DM) and the calculated blood flow.
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公开(公告)号:US11282170B2
公开(公告)日:2022-03-22
申请号:US16496620
申请日:2018-03-29
Applicant: KONINKLIJKE PHILIPS N.V.
Inventor: Romane Isabelle Marie-Bernard Gauriau , Christian Haase , Michael Grass , Javier Olivan Bescos , Raoul Florent
Abstract: Vasculature modeling systems and methods are disclosed that generate an enhanced 3D model based on a combination of two dimensional, 2D, imaging data of a region of interest and 3D imaging data of the region of interest. A hemodynamic simulation is performed using the enhanced 3D model to derive at least one hemodynamic parameter based on the hemodynamic simulation.
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公开(公告)号:US11172896B2
公开(公告)日:2021-11-16
申请号:US15551925
申请日:2015-12-04
Applicant: KONINKLIJKE PHILIPS N.V.
Inventor: Christian Haase , Dirk Schaefer , Eberhard Sebastian Hansis , Tobias Klinder , Michael Grass , Ming De Lin
Abstract: The present invention is directed towards a system and method for transarterial chemoembolization using differently sized drug-eluting microsphere beads filled with drugs and determining a delivered drug concentration using an imaging system.
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公开(公告)号:US11129691B2
公开(公告)日:2021-09-28
申请号:US15535455
申请日:2015-12-14
Applicant: KONINKLIJKE PHILIPS N.V.
Inventor: Bernardus Hendrikus Wilhelmus Hendriks , Michael Grass , Thomas Koehler , Harold Agnes Wilhelmus Schmeitz , Roland Proksa , Vishnu Vardhan Pully , Marco Andreas Jacobus Van As , Waltherus Cornelis Jozef Bierhoff , Franciscus Marinus Antonius Maria Van Gaal , Drazenko Babic
Abstract: An active marker device (100) is introducible into a human tissue and for tracking a region of interest of a human body. The active marker device includes a light source (101) for emitting light such that the emitted light can be detected by an optical sensor. In this way, the active marker device and/or the region of interest can be tracked by a tracking system including the optical sensor. The active marker device (100) also includes a switch (102) for turning the light source on and off and for operating the light source in a pulsed mode.
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公开(公告)号:US11071504B2
公开(公告)日:2021-07-27
申请号:US16305246
申请日:2017-06-05
Applicant: KONINKLIJKE PHILIPS N.V.
Inventor: Michael Grass , Dirk Schaefer
Abstract: The present invention relates to tomosynthesis. In order to further facilitate and improve the generation of three-dimensional image data, an X-ray imaging system (10) for calibration-free tomosynthesis is provided. The system comprises an imaging arrangement (12) with an X-ray detector unit (14) and an X-ray unit (16) comprising a plurality of X-ray sources (18). The system also comprises an image processing unit (20), an object receiving space (22), and a moving unit (24) for providing a relative movement between the imaging arrangement and an object of interest arranged at least partially in the object receiving space. The X-ray sources are provided in a known spatial relationship; the X-ray detector unit and the X-ray unit are also provided in a known spatial detector-sources-relationship. The moving unit provides a relative movement between the object of interest and the imaging arrangement in order to provide a plurality of system-to-object positions. The X-ray unit is configured to provide X-ray radiation to the object of interest from a plurality of different directions for each system-to-object position in order to provide a plurality of subsets of views with different viewing directions. The processing unit is configured to determine positions of the object in relation to the imaging arrangement based on the subsets of views, and to calculate a three-dimensional geometric position for each view of the subsets of views, and also to calculate a three-dimensional tomosynthesis reconstruction volume from the plurality of subsets of views.
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公开(公告)号:US20210012490A1
公开(公告)日:2021-01-14
申请号:US16969689
申请日:2019-01-29
Applicant: KONINKLIJKE PHILIPS N.V.
Inventor: Jörg Sabczynski , Michael Grass , Sven Peter Prevrhal
Abstract: An imaging system combines a probe for obtaining image data in respect of a structure of interest below a surface of a subject, a first camera for obtaining images of the surface of the subject and a second camera for capturing images of the environment. A surface model of the subjects surface is obtained, and the position and/or orientation of the probe is tracked on the surface. Image data acquired at different positions and orientations is stitched based on the tracked position of the probe.
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公开(公告)号:US10769787B2
公开(公告)日:2020-09-08
申请号:US16063920
申请日:2016-12-22
Applicant: KONINKLIJKE PHILIPS N.V.
Inventor: Michael Grass , Dirk Schäfer , Thirukumaran Thangaraj Kanagasabapathi , Bernardus Hendrikus Wilhelmus Hendriks
IPC: G06K9/00 , G06T7/00 , A61B90/00 , G06T7/11 , G06T7/33 , A61B6/00 , A61B8/08 , A61B34/20 , A61B17/00
Abstract: The present invention relates to providing a projection data for providing a guidance image. In order to provide an enhanced guiding image technique for generating a guidance image of the patient's anatomy to be projected on the body surface of the patient, such that a at least a basis for a corrected guidance image for a better correlation to the patient's current motion can be provided, in particular to the patient's current breathing motion state, a device (10) for providing a projection data set is provided that comprises a storage means (12), an input interface (14), a processing unit (16) and an output interface (18). The storage means is configured to store a pre-determined basis data set representing a 3D tomographic image of a subject (20). The input interface is configured to receive reference data representing a current spatial depiction at least of a target region (22) of the subject. The processing unit is configured to register the reference data on the pre-determined basis data set. The processing unit is further configured to transform, based on the reference data and the result of the registration, the pre-determined basis data set resulting in a working data set representing a transformed 3D tomographic image indicating the current spatial anatomy relation at least for the target region of the subject. The processing unit is also configured to segment the working data set resulting in a projection data set representing the target region of the subject. Still further, output interface is configured to provide the projection data set for a further purpose.
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50.
公开(公告)号:US10740932B2
公开(公告)日:2020-08-11
申请号:US15551202
申请日:2016-02-18
Applicant: KONINKLIJKE PHILIPS N.V.
Inventor: Bernard Johannes Brendel , Michael Grass , Peter George Van De Haar , William Edward Peter Van Der Sterren
Abstract: An image processing system (IPS) and related method for image reconstruction operations, in particular for spectral computed tomography imaging. The image reconstruction operation is based on optimizing a regularized objective or cost function. The objective function includes a regularization term (R) that incorporates, as a-priori knowledge, a known amount of a material resident within a field of view to be reconstructed.
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