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公开(公告)号:US20220162318A1
公开(公告)日:2022-05-26
申请号:US17547528
申请日:2021-12-10
Applicant: Genentech, Inc.
Inventor: Steven R. Leong , Andrew Polson , Paul Polakis , Yan Wu , Wei-Ching Liang , Ron Firestein
IPC: C07K16/28 , A61K47/65 , A61K47/68 , A61K38/08 , A61K39/395 , A61K51/10 , C07K16/30 , G01N33/569
Abstract: The invention provides anti-B7-H4 antibodies and immunoconjugates and methods of using the same.
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公开(公告)号:US11286302B2
公开(公告)日:2022-03-29
申请号:US16043274
申请日:2018-07-24
Applicant: Genentech, Inc.
Inventor: Steven R. Leong , Andrew Polson , Paul Polakis , Yan Wu , Wei-Ching Liang , Ron Firestein
IPC: A61K47/68 , C07K16/28 , C07K16/30 , A61K31/404 , A61K31/5517 , A61K31/706 , A61K38/05 , G01N33/574 , A61K39/00
Abstract: The invention provides anti-B7-H4 antibodies and immunoconjugates and methods of using the same.
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公开(公告)号:US11230600B2
公开(公告)日:2022-01-25
申请号:US16167000
申请日:2018-10-22
Applicant: Genentech, Inc.
Inventor: Steven R. Leong , Andrew Polson , Paul Polakis , Yan Wu , Wei-Ching Liang , Ron Firestein
IPC: C07K16/28 , A61K39/395 , A61K47/68 , G01N33/53 , A61K47/65 , A61K38/08 , A61K51/10 , C07K16/30 , G01N33/569 , A61K39/00
Abstract: The invention provides anti-B7-H4 antibodies and immunoconjugates and methods of using the same.
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公开(公告)号:US20190062432A1
公开(公告)日:2019-02-28
申请号:US16043274
申请日:2018-07-24
Applicant: Genentech, Inc.
Inventor: Steven R. Leong , Andrew Polson , Paul Polakis , Yan Wu , Wei-Ching Liang , Ron Firestein
IPC: C07K16/28 , G01N33/574 , C07K16/30 , A61K47/68 , A61K31/404 , A61K31/5517 , A61K31/706 , A61K38/05 , A61K39/00
Abstract: The invention provides anti-B7-H4 antibodies and immunoconjugates and methods of using the same.
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公开(公告)号:US20180312586A1
公开(公告)日:2018-11-01
申请号:US15918842
申请日:2018-03-12
Applicant: GENENTECH, INC.
Inventor: Shang-Fan Yu , Wei-Ching Liang , Yan Wu , Steven Leong , Andrew Polson
IPC: C07K16/28 , A61K47/68 , G01N33/574 , A61K39/00
Abstract: The invention provides anti-CD33 antibodies and immunoconjugates and methods of using the same.
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46.
公开(公告)号:US20180133315A1
公开(公告)日:2018-05-17
申请号:US15808795
申请日:2017-11-09
Applicant: Hoffmann-La Roche Inc. , Genentech, Inc.
Inventor: Christian Klein , Sabine Lang , Pablo Umana , Andrew Polson
IPC: A61K39/395 , A61K47/68 , A61K45/06 , A61K31/40 , C07K16/28
Abstract: The present invention is directed to the combination therapy of an afucosylated anti-CD20 antibody with a CD79b antibody-drug conjugate for the treatment of cancer, especially to the combination therapy of CD20 expressing cancers with an afucosylated humanized B-Ly1 antibody and a CD79b antibody-drug conjugate.
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公开(公告)号:US09896506B2
公开(公告)日:2018-02-20
申请号:US14734957
申请日:2015-06-09
Applicant: Genentech, Inc.
Inventor: Yvonne Chen , Mark Dennis , David Dornan , Kristi Elkins , Jagath Reddy Junutula , Andrew Polson , Bing Zheng
IPC: C07K16/28 , C07K16/30 , A61K39/395 , A61K47/68 , A61K38/05 , A61K45/06 , A61K51/10 , G01N33/574 , A61K31/537 , A61K39/00
CPC classification number: C07K16/2803 , A61K31/537 , A61K38/05 , A61K39/39558 , A61K45/06 , A61K47/6803 , A61K47/6811 , A61K47/6849 , A61K47/6867 , A61K51/1027 , A61K2039/505 , C07K16/3061 , C07K2317/24 , C07K2317/34 , C07K2317/40 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/73 , C07K2317/92 , G01N33/57492 , Y02A50/412 , Y02A50/423
Abstract: The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals, including immunoconjugates comprising anti-CD79b cysteine-engineered antibody huMA79b.v28, and to methods of using those compositions of matter for the same.
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公开(公告)号:US20180044421A1
公开(公告)日:2018-02-15
申请号:US15657476
申请日:2017-07-24
Applicant: Genentech, Inc.
Inventor: Bing Zheng , Andrew Polson , Cecilia Chiu , Wei-Ching Liang , Yan Wu
IPC: C07K16/28 , A61K47/68 , A61K51/10 , A61K31/706 , G01N33/574 , C07K16/30 , A61K31/5517
CPC classification number: C07K16/2851 , A61K31/5517 , A61K31/706 , A61K47/68 , A61K47/6817 , A61K47/6867 , A61K47/6889 , A61K51/1069 , A61K51/1093 , C07K16/3061 , C07K2317/14 , C07K2317/24 , C07K2317/33 , C07K2317/34 , C07K2317/52 , C07K2317/76 , C07K2317/77 , C07K2317/92 , C07K2317/94 , G01N33/57426 , G01N2333/7056
Abstract: The invention provides anti-CLL-1 antibodies and immunoconjugates and methods of using the same.
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49.
公开(公告)号:US20170306040A1
公开(公告)日:2017-10-26
申请号:US15452577
申请日:2017-03-07
Applicant: Hoffmann-La Roche Inc. , Genentech, Inc.
Inventor: Christian Klein , Sabine Lang , Pablo Umana , Andrew Polson
IPC: C07K16/28 , A61K39/395 , A61K45/06 , A61K39/00
Abstract: The present invention is directed to the combination therapy of an afucosylated anti-CD20 antibody with a CD22 antibody-drug conjugate for the treatment of cancer, especially to the combination therapy of CD20 expressing cancers with an afucosylated humanized B-Ly1 antibody and a CD22 antibody-drug conjugate.
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公开(公告)号:US09751946B2
公开(公告)日:2017-09-05
申请号:US14852369
申请日:2015-09-11
Applicant: Genentech, Inc.
Inventor: Bing Zheng , Andrew Polson , Cecilia Chiu , Wei-Ching Liang , Yan Wu
IPC: A61K39/395 , C07K16/28 , A61K31/5517 , A61K31/706 , A61K47/48 , A61K51/10 , C07K16/30 , G01N33/574
CPC classification number: C07K16/2851 , A61K31/5517 , A61K31/706 , A61K47/68 , A61K47/6817 , A61K47/6867 , A61K47/6889 , A61K51/1069 , A61K51/1093 , C07K16/3061 , C07K2317/14 , C07K2317/24 , C07K2317/33 , C07K2317/34 , C07K2317/52 , C07K2317/76 , C07K2317/77 , C07K2317/92 , C07K2317/94 , G01N33/57426 , G01N2333/7056
Abstract: The invention provides anti-CLL-1 antibodies and immunoconjugates and methods of using the same.
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