公开(公告)号：US20170014645A1

公开(公告)日：2017-01-19

申请号：US15277198

申请日：2016-09-27

Applicant: GENERAL ELECTRIC COMPANY

Inventor： Thomas Kwok-Fah Foo ,  Lowell Scott Smith ,  Kai Erik Thomenius ,  Sandeep Narendra Gupta ,  Luca Marinelli ,  Kedar Anil Patwardhan ,  Dominic Michael Graziani

IPC: A61N5/10 ,  A61B5/113 ,  A61B5/00 ,  A61B5/055 ,  A61B8/08

Abstract: Methods and systems using magnetic resonance and ultrasound for tracking anatomical targets for radiation therapy guidance are provided. One system includes a patient transport configured to move a patient between and into a magnetic resonance (MR) system and a radiation therapy (RT) system. An ultrasound transducer is also provided that is hands-free and electronically steerable, securely attached to the patient, such that the ultrasound transducer is configured to acquire four-dimensional (4D) ultrasound images concurrently with one of an MR acquisition or an RT radiation therapy session. The system also includes a controller having a processor configured to use the 4D ultrasound images and MR images from the MR system to control at least one of a photon beam spatial distribution or intensity modulation generated by the RT system. The system determines the previously-acquired correct MR images that represent a specific motion state at some time, t, by a plurality of transformations that allow the representation of the position of fiducial markers in the corresponding ultrasound images to match that of a prior ultrasound acquisition.

Abstract translation: 提供了使用磁共振和超声波跟踪放射治疗指导解剖靶标的方法和系统。 一个系统包括被配置为将患者移动到磁共振（MR）系统和放射治疗（RT）系统之间）的患者输送。 还提供了一种超声换能器，其是免提的并且可电子操纵的，牢固地附接到患者，使得超声换能器被配置为与MR采集或RT放射治疗之一同时获取四维（4D）超声图像 会话 该系统还包括具有处理器的控制器，其被配置为使用来自MR系统的4D超声图像和MR图像来控制RT系统产生的光子束空间分布或强度调制中的至少一个。 该系统通过允许在对应的超声图像中的基准标记的位置的表示与先前的超声波获取相匹配的多个变换来确定在某时刻t表示特定运动状态的先前获得的正确MR图像 。

公开(公告)号：US20160174868A1

公开(公告)日：2016-06-23

申请号：US14577770

申请日：2014-12-19

Applicant: GENERAL ELECTRIC COMPANY ,  MEMORIAL SLOAN-KETTERING CANCER CENTER

Inventor： Matthew Richard Tarasek ,  Thomas Kwok-Fah Foo ,  Desmond Teck Beng Yeo ,  Oguz Akin

IPC: A61B5/055 ,  G01R33/48 ,  A61N1/00 ,  A61B5/01 ,  A61B18/08 ,  A61B18/02 ,  A61N7/02 ,  A61N5/00 ,  G01R33/31 ,  A61B5/00

CPC classification number: A61B5/055 ,  A61B5/0051 ,  A61B5/0053 ,  A61B5/01 ,  A61B5/4836 ,  A61B5/7278 ,  A61B5/7282 ,  A61F7/02 ,  A61F2007/0054 ,  A61F2007/0071 ,  A61F2007/0095 ,  A61F2007/0295 ,  A61N7/02 ,  G01R33/4804 ,  G01R33/50 ,  G01R33/5608 ,  G01R33/56341

Abstract: The present disclosure describes non-invasive approaches for delineating and characterizing tissue using MR imaging over a range of treatment levels. By way of example, tumor tissue may be distinguished and delineated from other tissue, such as muscle tissue. Further, tumor tissue may be characterized as malignant or benign using such approaches.

Abstract translation: 本公开描述了在一系列治疗水平上使用MR成像描绘和表征组织的非侵入性方法。 举例来说，可以区分肿瘤组织并从其它组织例如肌肉组织描绘。 此外，使用这种方法可以将肿瘤组织表征为恶性或良性。

公开(公告)号：US20140159712A1

公开(公告)日：2014-06-12

申请号：US13970339

申请日：2013-08-19

Applicant: General Electric Company

Inventor： Dominic Michael Graziani ,  Thomas Kwok-Fah Foo ,  Luca Marinelli ,  Daniel Eugene Meyer ,  Bruce Allen Hay

IPC: G01N27/72

CPC classification number: G01R33/1276 ,  A61B5/00 ,  A61B5/0515

Abstract: Magnetic material imaging (MMI) system including first and second sets of field-generating coils. Each of the field-generating coils of the first and second sets has an elongated segment that extends along an imaging axis of the medical imaging system. The imaging axis extends through a region-of-interest (ROI) of an object. The elongated segments of the first set of field-generating coils are positioned opposite the elongated segments of the second set of field-generating coils and the ROI is located between the first and second sets of field-generating coils. The MMI system also includes a coil-control module configured to control a flow of current through the first and second sets of field-generating coils to generate a selection field and to generate a drive field. The selection and drive fields combine to form a movable 1D field free region (FFR) that extends through the ROI.

Abstract translation: 磁材料成像（MMI）系统包括第一组和第二组励磁线圈。 第一组和第二组的每个场产生线圈具有沿着医学成像系统的成像轴线延伸的细长部分。 成像轴延伸穿过物体的感兴趣区域（ROI）。 第一组场产生线圈的细长段与第二组场产生线圈的细长段相对设置，并且ROI位于第一组和第二组场产生线圈之间。 MMI系统还包括线圈控制模块，该线圈控制模块被配置为控制通过第一和第二组场产生线圈的电流流动以产生选择场并产生驱动场。 选择和驱动领域相结合，形成一个延伸穿过ROI的可移动1D无域区域（FFR）。