公开(公告)号：US20200341089A1

公开(公告)日：2020-10-29

申请号：US16858848

申请日：2020-04-27

Applicant: Case Western Reserve University

Inventor： Debra McGivney ,  Mark A. Griswold

IPC: G01R33/48 ,  G01R33/561 ,  G01R33/56

Abstract: A system and method is provided for improved magnetic resonance fingerprinting (MRF) data dictionary matching using an MRF dictionary having entries with an inner product storing tissue properties.

公开(公告)号：US10761167B2

公开(公告)日：2020-09-01

申请号：US16387264

申请日：2019-04-17

Applicant: Case Western Reserve University

Inventor： Mark A. Griswold ,  Mingrui Yang

IPC: G01R33/48 ,  G06N20/00 ,  G01R33/56

Abstract: A method for creating a dictionary for a magnetic resonance fingerprinting (MRF) reconstruction includes training a semi-supervised learning system based on at least a set of MRF data and a set of control variables and generating a plurality of signal evolutions using the trained semi-supervised learning system. The method also includes generating an MRF dictionary using the plurality of signal evolutions generated using the trained semi-supervised learning system and storing the MRF dictionary in a memory. In one embodiment, the semi-supervised learning system is a MRF generative adversarial network (GAN).

公开(公告)号：US20200150197A1

公开(公告)日：2020-05-14

申请号：US16681454

申请日：2019-11-12

Applicant: Case Western Reserve University

Inventor： Andrew Dupuis ,  Nicole Seiberlich ,  Dominique Franson ,  Mark A. Griswold

IPC: G01R33/28 ,  G01R33/56 ,  G06T11/00 ,  G06F3/01 ,  G06F3/0481 ,  G06F3/0484 ,  A61B34/20 ,  A61B5/00 ,  A61B5/055

Abstract: A system for displaying and interacting with magnetic resonance imaging (MRI) data acquired using an MRI system includes an image reconstruction module configured to receive the MRI data and to reconstruct a plurality of images using the MRI data, an image rendering module coupled to the image reconstruction module and configured to generate at least one multidimensional image based on the plurality of images and a user interface device coupled to the image rendering module and located proximate to a workstation of the MRI system. The user interface device is configured to display the at least one multidimensional image in real-time and to facilitate interaction by a user with the multidimensional image in a virtual reality or augmented reality environment.

公开(公告)号：US10564243B2

公开(公告)日：2020-02-18

申请号：US15944637

申请日：2018-04-03

Applicant: Case Western Reserve University

Inventor： Mark A. Griswold ,  Bhairav Bipin Mehta ,  Simone Coppo

IPC: G01V3/00 ,  G01R33/561 ,  G01R33/50 ,  G01R33/56 ,  A61B5/055 ,  G01R33/34 ,  G01R33/38

Abstract: A system and method is provided for performing a magnetic resonance fingerprinting (MRF) study in the face of inhomogeneous magnetic fields. The process includes performing a balanced steady-state free precession (bSSFP) pulse sequence multiple times to acquire a multiple MRF datasets from at region of interest (ROI) in a subject, wherein performing the multiple bSSFP pulse sequences includes cycling through multiple phase patterns that differ across the multiple times. The process also includes comparing the multiple MRF datasets with a MRF dictionary to determine at least one tissue property indicated by each of the multiple MRF datasets, producing an aggregated indication of the at least one tissue property, and producing at least one map of the at least one tissue property using the aggregated indication of the at least one tissue property.

公开(公告)号：US10511261B2

公开(公告)日：2019-12-17

申请号：US15481415

申请日：2017-04-06

Applicant: Case Western Reserve University

Inventor： Michael Twieg ,  Mark A. Griswold ,  Soumyajit Mandal

IPC: G01V3/00 ,  H03D7/12 ,  G01R33/36 ,  H03D7/16 ,  G01R33/3415

Abstract: An apparatus, a system, and a chip are provided for improving RF system performance in MRI systems. The apparatus includes a radio-frequency (RF) coil array disposed at least partially in a coil housing, where the RF coil array may include at least one coil configured to receive magnetic resonance (MR) RF signals. The apparatus also includes a mixer disposed in the coil housing and electronically connected to the RF coil array, where the mixer converts MR RF signals from the RF coil array to intermediate-frequency (IF) signals. An electronic amplifier is disposed in the coil housing. The electronic amplifier is electronically connected to the mixer and is configured to amplify IF signals from the mixer to amplified IF signals.

公开(公告)号：US20190340463A1

公开(公告)日：2019-11-07

申请号：US16378166

申请日：2019-04-08

Applicant: Case Western Reserve University

Inventor： Mathias Nittka ,  Gregor Korzdorfer ,  Peter Speier ,  Mark A. Griswold ,  Yun Liang

IPC: G06K9/52 ,  G01R33/56 ,  G01R33/50 ,  G06T7/00

Abstract: A method for performing magnetic resonance fingerprinting includes acquiring a plurality of MR image datasets using at least two pulse sequence types, the plurality of MR image datasets representing signal evolutions for image elements in a region of interest, comparing the plurality of MR image datasets to a dictionary of signal evolutions to identify at least one parameter of the MR image datasets and generating a report indicating the at least one parameter of the MR image datasets.

公开(公告)号：US20190285712A1

公开(公告)日：2019-09-19

申请号：US16351404

申请日：2019-03-12

Applicant: Case Western Reserve University

Inventor： Vikas Gulani ,  Satyam Ghodasara ,  Katherine Wright ,  Nicole Seiberlich ,  Mark A. Griswold

IPC: G01R33/56 ,  A61B5/055 ,  G01R33/563

Abstract: A method for determining quantitative parameters for dynamic contrast-enhanced MR data includes acquiring a set of contrast-enhanced MR data for a region of interest using a T1-weighted pulse sequence, generating at least one contrast concentration curve based on the set of contrast-enhanced MR data, accessing a comprehensive dictionary of contrast concentration curves and generating a grouped dictionary that has a plurality of groups based on the comprehensive dictionary. Each group includes a plurality of correlated contrast concentration curves and a group representative signal for the group. The method also includes comparing a contrast concentration curve with the group representative signal of each group to select a group, comparing the contrast concentration curve to the plurality of correlated contrast concentration curves in the selected group to identify a set of quantitative parameters for the concentration curve and generating a report including the set of quantitative parameter.

公开(公告)号：US20180372825A1

公开(公告)日：2018-12-27

申请号：US16053873

申请日：2018-08-03

Applicant: Case Western Reserve University

Inventor： Mark A. Griswold ,  Yun Jiang ,  Dan Ma ,  Anagha Deshmane ,  Chaitra Badve ,  Vikas Gulani ,  Jeffrey L. Sunshine

IPC: G01R33/56 ,  G01R33/50 ,  G01R33/48

Abstract: Apparatus, methods, and other embodiments associated with NMR fingerprinting are described. One example NMR apparatus includes an NMR logic that repetitively and variably samples a (k, t, E) space associated with an object to acquire a set of NMR signals that are associated with different points in the (k, t, E) space. Sampling is performed with t and/or E varying in a non-constant way. The NMR apparatus may also include a signal logic that produces an NMR signal evolution from the NMR signals, and a characterization logic that characterizes a resonant species in the object as a result of comparing acquired signals to reference signals. The NMR signal evolution may be assigned to a cluster based on the characterization of the resonant species. Cluster overlay maps may be produced simultaneously based, at least in part, on the clustering. The clusters may be associated with different tissue types.

公开(公告)号：US20180292497A1

公开(公告)日：2018-10-11

申请号：US15947558

申请日：2018-04-06

Applicant: Case Western Reserve University

Inventor： Bhairav Bipin Mehta ,  Mark A. Griswold

IPC: G01R33/56 ,  G01R33/54 ,  G01R33/50 ,  G01R33/48

CPC classification number: G01R33/5608 ,  G01R33/4828 ,  G01R33/50 ,  G01R33/543 ,  G01R33/56509

Abstract: Methods for magnetic resonance fingerprinting (“MRF”) that are more robust to patient motion than conventional MRF techniques are described. The methods described in the present disclosure provide an image reconstruction algorithm for MRF that decreases the motion sensitivity of MRF.

公开(公告)号：US20170293003A1

公开(公告)日：2017-10-12

申请号：US15481415

申请日：2017-04-06

Applicant: Case Western Reserve University

Inventor： Michael Twieg ,  Mark A. Griswold ,  Soumyajit Mandal

IPC: G01R33/36 ,  H03D7/12

CPC classification number: H03D7/12 ,  G01R33/3415 ,  G01R33/3621 ,  H03D7/165 ,  H03D2200/0086

Abstract: An apparatus, a system, and a chip are provided for improving RF system performance in MRI systems. The apparatus includes a radio-frequency (RF) coil array disposed at least partially in a coil housing, where the RF coil array may include at least one coil configured to receive magnetic resonance (MR) RF signals. The apparatus also includes a mixer disposed in the coil housing and electronically connected to the RF coil array, where the mixer converts MR RF signals from the RF coil array to intermediate-frequency (IF) signals. An electronic amplifier is disposed in the coil housing. The electronic amplifier is electronically connected to the mixer and is configured to amplify IF signals from the mixer to amplified IF signals.