公开(公告)号：US20180036495A1

公开(公告)日：2018-02-08

申请号：US15226638

申请日：2016-08-02

申请人： Becton, Dickinson and Company

发明人： Gary Searle ,  Andrew Burke ,  Peter Costello ,  Kenneth Focht ,  Francis L. Ross

IPC分类号： A61M5/48 ,  A61M5/32 ,  A61M5/20

CPC分类号： A61M5/482 ,  A61M5/16804 ,  A61M5/16831 ,  A61M5/20 ,  A61M5/3286 ,  A61M2205/3331 ,  A61M2205/3569

摘要： A flow sensor is provided to enable volumetric dose data to be acquired automatically by sampling flow rates of insulin measured by a flow sensor exposed to a flow manifold though which the insulin flows. The flow sensor preferably connects to a standard insulin pen on one end, and to a standard pen needle on the other end. Particular geometries and algorithms are utilized to accommodate the unique requirements of insulin flow determination during an injection event.

公开(公告)号：US09827373B2

公开(公告)日：2017-11-28

申请号：US14895302

申请日：2014-06-02

申请人： Novo Nordisk A/S

发明人： Simon Roervig ,  Steffen Hansen

IPC分类号： A61M5/20 ,  A61M5/315 ,  A61M5/24 ,  A61M5/48 ,  A61M5/32

CPC分类号： A61M5/20 ,  A61M5/24 ,  A61M5/2466 ,  A61M5/3155 ,  A61M5/31553 ,  A61M5/31561 ,  A61M5/3157 ,  A61M5/3158 ,  A61M5/31583 ,  A61M5/486 ,  A61M2005/2013 ,  A61M2005/2407 ,  A61M2005/3267 ,  A61M2205/43 ,  A61M2205/581

摘要： The present invention relates to a torsion spring based automatic injection device for apportioning set doses of a liquid drug and which injection device is provided with an End-of-Dose feedback mechanism providing a user with an audible signal once the set dose has been injected. During injection, the scale drum rotates back to its “zero” position under influence of the torsion spring. This rotation is halted shortly before reaching the “zero” position by stopping means. The scale drum is thereafter only allowed to continue rotation and thus reach the “zero” position once the torque applied to the scale drum by the torsion spring surpasses a threshold value.

公开(公告)号：US09629959B2

公开(公告)日：2017-04-25

申请号：US15209389

申请日：2016-07-13

申请人： Antares Pharma, Inc.

发明人： Paul R. Lesch

IPC分类号： A61M5/20 ,  A61M5/28 ,  A61M5/30 ,  A61M5/178 ,  A61M5/48 ,  A61M5/32

CPC分类号： A61M5/2033 ,  A61M5/178 ,  A61M5/28 ,  A61M5/30 ,  A61M5/3202 ,  A61M5/46 ,  A61M5/484 ,  A61M2005/2013 ,  A61M2005/206

摘要： A jet injector that includes a prefilled syringe. The syringe includes a fluid chamber that contains a medicament. The syringe also has an injection-assisting needle, and a plunger is movable within the fluid chamber. A housing is configured for allowing insertion of the needle to a penetration depth. An energy source is configured for biasing the plunger to produce an injecting pressure in the medicament in the fluid chamber of between about 80 and 1000 p.s.i. to jet inject the medicament from the fluid chamber through the needle to an injection site.

公开(公告)号：US09604005B2

公开(公告)日：2017-03-28

申请号：US14052568

申请日：2013-10-11

申请人： Jürgen Stockmar

发明人： Jürgen Stockmar

IPC分类号： A61M5/30 ,  A61M5/48

CPC分类号： A61M5/3007 ,  A61M5/30 ,  A61M5/484

摘要： The invention relates to a device for injecting a medium into or underneath the skin with a series of pressure pulses. The device includes a reservoir (1) for the medium, an application unit (10) to inject the medium into or under the skin, a hydraulic high-pressure pump (6) to pump the medium out of the reservoir (1) into the applicator unit (10), and an electronic control unit (11) that is suitable for regulating the applicator unit (10) such that the medium is injected with a series of pressure pulses into or underneath the skin.

公开(公告)号：US20170035606A1

公开(公告)日：2017-02-09

申请号：US15304729

申请日：2015-04-17

申请人： SEIRATHERM GMBH

发明人： Matthias ROTH ,  Thomas REICHTHALHAMMER

IPC分类号： A61F7/12 ,  A61M5/48 ,  A61M5/44

CPC分类号： A61F7/12 ,  A61F2007/0054 ,  A61F2007/0063 ,  A61F2007/0093 ,  A61F2007/0095 ,  A61F2007/0096 ,  A61F2007/126 ,  A61M5/142 ,  A61M5/44 ,  A61M5/48 ,  A61M2005/14208

摘要： Apparatus for controlling a body temperature with a controller. The controller is adapted to control the body temperature by controlling at least two different body temperature adaption devices, wherein one body temperature adaption device is an infusion device (200); and wherein at least one further body temperature adaption device (300) is different from the one body temperature adaptation device and, preferably, not an infusion device.

摘要翻译： 用于通过控制器控制体温的装置。 控制器适于通过控制至少两种不同的身体温度适应装置来控制体温，其中一个体温适应装置是输注装置（200）; 并且其中至少一个另外的体温适应装置（300）不同于一个体温适应装置，并且优选地，不是输注装置。

公开(公告)号：US09539386B2

公开(公告)日：2017-01-10

申请号：US14997068

申请日：2016-01-15

申请人： MEDTRONIC MINIMED, INC.

发明人： Mohsen Askarinya ,  Richard L. Brown ,  Colin A. Chong ,  Patrick W. Kinzie ,  Randal Schulhauser ,  Jeff M. Cherry ,  Tyler S. Stevenson

IPC分类号： A61M5/32 ,  A61M5/142 ,  A61M5/48 ,  A61M5/158 ,  A61M5/145 ,  A61M5/168 ,  A61M39/02 ,  A61M5/172 ,  A61M5/315

CPC分类号： A61M5/14248 ,  A61M5/145 ,  A61M5/1483 ,  A61M5/152 ,  A61M5/158 ,  A61M5/16804 ,  A61M5/16813 ,  A61M5/172 ,  A61M5/31511 ,  A61M5/3287 ,  A61M5/484 ,  A61M39/02 ,  A61M39/0247 ,  A61M2005/14252 ,  A61M2005/14506 ,  A61M2005/1585 ,  A61M2005/1726 ,  A61M2039/0205 ,  A61M2205/0244 ,  A61M2205/0294 ,  A61M2205/825

摘要： An on-body injector and method of use including an on-body injector for use with an injection device. The on-body injector includes a bolus reservoir; a bolus injection needle in fluid communication with the bolus reservoir, the bolus injection needle having a bolus injection needle tip aligned with the injection port, the bolus injection needle being slideably biased away from the injection port to define a gap between the bolus injection needle tip and the injection port; and a button operably connected to the bolus injection needle to slide the bolus injection needle along the injection axis. The button is operable to advance the bolus injection needle tip to close the gap and advance the bolus injection needle tip into the injection port. The button is further operable to advance a plunger through the bolus reservoir to deliver a predetermined bolus volume to the patient through the injection flow path.

摘要翻译： 一种体内注射器和使用方法，包括与注射装置一起使用的体内注射器。 体内注射器包括推注储液器; 与推注储液器流体连通的推注注射针，推注注射针具有与注射口对准的推注注射针头，推注注射针可滑动地偏离注射端口，以限定推注注射针尖之间的间隙 和注射口; 以及可操作地连接到推注注射针以沿着注射轴滑动推注注射针的按钮。 该按钮可操作以推进推注注射针尖以闭合间隙并将推注注射针尖推进注射口。 该按钮还可操作以使柱塞前进通过推注储器以通过注射流动路径向患者输送预定的推注体积。

公开(公告)号：US20160158462A1

公开(公告)日：2016-06-09

申请号：US14962508

申请日：2015-12-08

申请人： Becton, Dickinson and Company

发明人： Ryan SCHOONMAKER ,  Michel BRUEHWILER ,  Ira SPOOL ,  Melissa ROSEN

IPC分类号： A61M5/48 ,  A61M5/20 ,  A61M5/315 ,  A61M5/142

CPC分类号： A61M5/48 ,  A61M5/14216 ,  A61M5/204 ,  A61M5/286 ,  A61M5/3146 ,  A61M5/31511 ,  A61M5/31553 ,  A61M5/3158 ,  A61M2005/3128 ,  A61M2005/31518 ,  A61M2005/3152

摘要： A dual-chambered drug delivery device, comprising a cartridge having a first chamber for storing a medicament, a second chamber in fluid communication with said first chamber, a dose setting member for setting a medicament dose to be injected at an injection site, a piston disposed in said second chamber, an upward stroke of said piston drawing a portion of the medicament dose into said second chamber and a downward stroke of said piston expelling the portion of the medicament dose, a needle communicating with said second chamber for sequentially injecting portions of the medicament dose into the injection site, a drive screw movably connected to said dose setting member such that rotation of said dose setting member moves said drive screw upwardly, and a rack movably connected to said drive screw such that downward movement of said drive screw during the medicament dose injection rotates said rack.

摘要翻译： 一种双腔药物输送装置，包括具有用于储存药物的第一腔室和与所述第一腔室流体连通的第二腔室的药筒，用于设定在注射部位注射的药物剂量的剂量设定部件，活塞 设置在所述第二室中，所述活塞的向上冲程将药物剂量的一部分吸入所述第二腔室中，并且所述活塞的向下冲程排出药物剂量的一部分，与所述第二腔室连通的针，以顺序地将部分 药物剂量进入注射部位，驱动螺杆可移动地连接到所述剂量设定部件，使得所述剂量设定部件的旋转向上移动所述驱动螺杆;以及齿条，其可移动地连接到所述驱动螺杆，使得所述驱动螺杆在 药物剂量注射使所述齿条旋转。

公开(公告)号：US20160129178A1

公开(公告)日：2016-05-12

申请号：US14997068

申请日：2016-01-15

申请人： MEDTRONIC MINIMED, INC.

发明人： Mohsen Askarinya ,  Richard L. Brown ,  Colin A. Chong ,  Patrick W. Kinzie ,  Randal Schulhauser ,  Jeff M. Cherry ,  Tyler S. Stevenson

IPC分类号： A61M5/142 ,  A61M5/172 ,  A61M5/48 ,  A61M5/168

CPC分类号： A61M5/14248 ,  A61M5/145 ,  A61M5/1483 ,  A61M5/152 ,  A61M5/158 ,  A61M5/16804 ,  A61M5/16813 ,  A61M5/172 ,  A61M5/31511 ,  A61M5/3287 ,  A61M5/484 ,  A61M39/02 ,  A61M39/0247 ,  A61M2005/14252 ,  A61M2005/14506 ,  A61M2005/1585 ,  A61M2005/1726 ,  A61M2039/0205 ,  A61M2205/0244 ,  A61M2205/0294 ,  A61M2205/825

摘要： An on-body injector and method of use including an on-body injector for use with an injection device. The on-body injector includes a bolus reservoir; a bolus injection needle in fluid communication with the bolus reservoir, the bolus injection needle having a bolus injection needle tip aligned with the injection port, the bolus injection needle being slideably biased away from the injection port to define a gap between the bolus injection needle tip and the injection port; and a button operably connected to the bolus injection needle to slide the bolus injection needle along the injection axis. The button is operable to advance the bolus injection needle tip to close the gap and advance the bolus injection needle tip into the injection port. The button is further operable to advance a plunger through the bolus reservoir to deliver a predetermined bolus volume to the patient through the injection flow path.

公开(公告)号：US09320846B2

公开(公告)日：2016-04-26

申请号：US13839771

申请日：2013-03-15

申请人： Osprey Medical, Inc.

发明人： Matthew M. Burns ,  Tuan M. Doan ,  Rodney L. Houfburg ,  David M. Kaye ,  Daniel R. Mans ,  Todd J. Mortier

IPC分类号： A61M5/48 ,  A61M5/00 ,  A61M5/142 ,  F04B11/00 ,  A61M5/168 ,  A61M25/00 ,  G06F19/00 ,  A61M39/24

CPC分类号： A61M5/1413 ,  A61M5/007 ,  A61M5/14212 ,  A61M5/14216 ,  A61M5/145 ,  A61M5/16881 ,  A61M5/48 ,  A61M5/482 ,  A61M5/484 ,  A61M5/488 ,  A61M25/0075 ,  A61M39/24 ,  A61M2025/0076 ,  A61M2039/2413 ,  A61M2205/3331 ,  A61M2205/3334 ,  A61M2205/3337 ,  A61M2205/3341 ,  A61M2205/3344 ,  A61M2205/3355 ,  A61M2206/22 ,  A61M2210/125 ,  A61M2210/127 ,  F04B11/0033 ,  G06F19/00 ,  G06F19/3456 ,  G06F19/3468

摘要： Devices, systems and methods for controlling, regulating, altering, transforming or otherwise modulating the delivery of a substance to a delivery site. The devices, systems and methods optimize the delivery of the substance to an intended site, such as a vessel, vascular bed, organ and/or other corporeal structures, while reducing inadvertent introduction or reflux substance to other vessels, vascular beds, organs, and/or other structures, including systemic introduction.

摘要翻译： 用于控制，调节，改变，转化或以其他方式调节物质输送到输送部位的装置，系统和方法。 装置，系统和方法优化物质输送到预期部位，例如血管，血管床，器官和/或其他体内结构，同时减少对其他血管，血管床，器官和/ /或其他结构，包括系统介绍。

公开(公告)号：US09238112B2

公开(公告)日：2016-01-19

申请号：US12998840

申请日：2009-12-08

申请人： Ryan Schoonmaker ,  Michel Bruehwiler ,  Ira Spool ,  Melissa Rosen

发明人： Ryan Schoonmaker ,  Michel Bruehwiler ,  Ira Spool ,  Melissa Rosen

IPC分类号： A61M5/48 ,  A61M5/142 ,  A61M5/20 ,  A61M5/28 ,  A61M5/31 ,  A61M5/315

CPC分类号： A61M5/48 ,  A61M5/14216 ,  A61M5/204 ,  A61M5/286 ,  A61M5/3146 ,  A61M5/31511 ,  A61M5/31553 ,  A61M5/3158 ,  A61M2005/3128 ,  A61M2005/31518 ,  A61M2005/3152

摘要： A dual-chambered drug delivery device (201) includes a cartridge (211) having a first chamber (212) for storing a medicament and a second chamber (211) in fluid communication with the first chamber (212). A dose setting member (241) is used to set a medicament dose to be injected at an injection site. A piston (281) is disposed in the second chamber (221). An upward stroke of the piston (281) draw a portion of the medicament dose into the second chamber (221) and a downward stroke of the piston (281) expels the portion of the medicament dose. A needle (205) communicates with the second chamber (221) for sequentially injecting the portions of the medicament dose into the injection site.

摘要翻译： 双腔药物输送装置（201）包括具有用于储存药物的第一腔室（212）和与第一腔室（212）流体连通的第二腔室（211）的药筒（211）。 剂量设定部件（241）用于设定在注射部位注射的药物剂量。 活塞（281）设置在第二腔室（221）中。 活塞（281）的向上行程将药物剂量的一部分吸入第二腔室（221），并且活塞（281）的向下冲程排出药物剂量的一部分。 针（205）与第二腔室（221）连通，用于将药物剂量的部分顺序地注入注射部位。