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804 条记录 (耗时 0.029 秒)

    Canna and Shea topical cream
    31.
    发明授权
    Canna and Shea topical cream 失效
    Canna和Shea面霜

    公开(公告)号：US08425954B2

    公开(公告)日：2013-04-23

    申请号：US13192442

    申请日：2011-07-27

    申请人： Sonya Stone

    发明人： Sonya Stone

    IPC分类号： A61K36/18 ,  A61P29/00

    CPC分类号： A61K9/0014 ,  A61K8/922 ,  A61K8/97 ,  A61K8/986 ,  A61K36/185 ,  A61K2800/31 ,  A61Q17/04 ,  A61K2300/00

    摘要： A THC composition comprises cannabis leaves simmered in butter, which is then filtered and cooled, and then mixed with shea butter. The resulting compound is used for topical skin relief, sun protection for skin and other uses. The butter used for simmering the cannabis leaves may be cow butter, sheep butter, olive oil, cooking oil, and other compositions.

    摘要翻译： THC组合物包含在黄油中煎煮的大麻叶，然后将其过滤并冷却，然后与牛油果混合。 所得化合物用于局部皮肤缓解，皮肤防晒和其他用途。 用于煨大麻叶的黄油可以是牛油，羊油，橄榄油，食用油和其他组合物。

    Pure sustained dichroa ferbrifuga alkone formulation
    36.
    发明申请
    Pure sustained dichroa ferbrifuga alkone formulation 审中-公开
    纯持久二氯噻唑烷酮配方

    公开(公告)号：US20110033546A1

    公开(公告)日：2011-02-10

    申请号：US12462770

    申请日：2009-08-10

    申请人： Xiao Qi Wang

    发明人： Xiao Qi Wang

    IPC分类号： A61K9/14 ,  A61K36/18 ,  B05D3/00 ,  A61P35/00

    CPC分类号： A61K36/185 ,  A61K9/2081 ,  A61K9/4808 ,  A61K9/5047 ,  A61K9/5078 ,  A61K47/6949 ,  B82Y5/00 ,  Y02A50/411

    摘要： Now is provided a new sustained release drug preparation comprising such an inclusion complex of a medical compound with dichroa febrifuga alkone derivative (DFAD), which sustains or retards the dissolution and release of the DFAD at a controlled rate from the inclusion complex and hence from the drug preparation containing the DFAD, so as to maintain the concentration of the DFAD in blood at an effective level for prolonged time.

    摘要翻译： 现在提供一种新的持续释放药物制剂，其包含医药化合物与二氯双酚酯衍生物（DFAD）的包合物复合物，其以受控的速率从包合物维持或延缓DFAD的溶解和释放，因此从 含有DFAD的药物制剂，以维持DFAD在血液中的浓度长时间有效。

    Prolactin induced increase in neural stem cell numbers
    37.
    发明授权
    Prolactin induced increase in neural stem cell numbers 失效
    催乳素诱导神经干细胞数增加

    公开(公告)号：US07884072B2

    公开(公告)日：2011-02-08

    申请号：US12051240

    申请日：2008-03-19

    申请人： Tetsuro Shingo ,  Samuel Weiss

    发明人： Tetsuro Shingo ,  Samuel Weiss

    IPC分类号： A61K36/15 ,  A61K36/18 ,  C12N5/074 ,  C12N5/0797

    CPC分类号： C12N5/0623 ,  A61K35/12 ,  A61K38/2257 ,  A61K38/27 ,  A61K38/30 ,  A61K2300/00

    摘要： The present invention provides a method of increasing neural stem cell numbers or neurogenesis by using prolactin. The method can be practiced in vivo to obtain more neural stem cells in situ, which can in turn produce more neurons or glial cells to compensate for lost or dysfunctional neural cells. The method can also be practiced in vitro to produce a large number of neural stem cells in culture. The cultured stem cells can be used, for example, for transplantation treatment of patients or animals suffering from neurodegenerative diseases or conditions. In addition, since neural stem cells are a source for olfactory neurons, the present invention also provides methods of increasing olfactory neurons and enhancing olfactory functions.

    摘要翻译： 本发明提供了通过使用催乳素来增加神经干细胞数量或神经发生的方法。 该方法可以在体内实施以获得更多的原位神经干细胞，其又可产生更多的神经元或神经胶质细胞以补偿丢失或功能失调的神经细胞。 该方法也可以在体外实施以在培养物中产生大量的神经干细胞。 培养的干细胞可用于例如患有神经变性疾病或病症的患者或动物的移植治疗。 此外，由于神经干细胞是嗅觉神经元的来源，本发明还提供增加嗅觉神经元和增强嗅觉功能的方法。

    Pharmaceutical product and analysis model for hormone replacement therapy for women and prevention of some cancers and uterine myomas
    38.
    发明申请
    Pharmaceutical product and analysis model for hormone replacement therapy for women and prevention of some cancers and uterine myomas 有权
    用于妇女激素替代疗法的药物产品和分析模型以及预防某些癌症和子宫肌瘤

    公开(公告)号：US20100310690A1

    公开(公告)日：2010-12-09

    申请号：US12802083

    申请日：2010-05-28

    申请人： Andres Tchernitchin ,  Leonardo Gaete ,  Rodrigo Bustamante

    发明人： Andres Tchernitchin ,  Leonardo Gaete ,  Rodrigo Bustamante

    IPC分类号： A61K36/48 ,  A61K36/18 ,  A61K36/185 ,  A61P35/00 ,  A61P37/08

    CPC分类号： A61K36/185 ,  A61K36/48 ,  A61K2300/00

    摘要： The present disclosure describes a study of estrogenic activity present in various plant species, selectively inducing some but not all estrogenic responses in the uterus. Prepubertal female rats were treated sequentially with various extracts or decoctions of different plant species or its vehicle, followed 1 h later by treatment with estradiol-17β (E) or its solvent. Uteri were excised under anesthesia and histologically processed for eosinophil quantification and morphometric evaluation of various uterine responses to estrogen, at 6 or 24 h after hormone or vehicle treatment. Besides extracts or decoctions, pure phytoestrogens were also used. Additionally, human mammary cancer cells MCF-7 or MDAMB-231 were cultured in presence of the extract (or decoction), E, both or solvent and cell proliferation was evaluated. Various extracts or decoction displayed selective estrogenic and/or antiestrogenic action for some but not all parameters of estrogen stimulation in the uterus and inhibited growth of human mammary cells in culture or antagonized the estrogen-induced increase in their growth. Present results reveal, for the first time, a dissociation of responses to estrogen by phytoestrogens, suggesting its possible therapeutic application as estrogenic compounds not inducing cell proliferation and reveal the anticancerous effect of some of the extracts with possible therapeutic relevance. The dissociation of responses to estrogen additionally suggest therapeutic applications in estrogen-related diseases (for instance, premenstrual syndrome, endometriosis, etc.); the inhibition of eosinophil degranulation suggest an application in diseases related to eosinophils (hypereosinophilic syndrome, allergic and hypersensitivity diseases).

    摘要翻译： 本公开描述了存在于各种植物物种中的雌激素活性的研究，在子宫中选择性地诱导一些但不是全部的雌激素反应。 根据不同植物种类或其载体的各种提取物或煎剂依次处理青春期前大鼠，随后1h后用雌二醇17和bgr处理。 （E）或其溶剂。 在麻醉下切除子宫，并在激素或载体处理后6或24小时，组织学处理嗜酸性粒细胞定量和形态学评估对雌激素的各种子宫反应。 除了提取物或煎剂之外，还使用纯植物雌激素。 另外，在提取物（或煎剂）E的存在下培养人乳腺癌细胞MCF-7或MDAMB-231，两者或溶剂，并评估细胞增殖。 各种提取物或煎剂对子宫中雌激素刺激的一些但不是全部参数显示选择性雌激素和/或抗雌激素作用，并抑制培养中人乳腺细胞的生长或拮抗雌激素诱导的其生长增加。 目前的结果首次揭示植物雌激素对雌激素的反应解离，表明其可能的治疗应用作为雌激素化合物不诱导细胞增殖，并显示出某些提取物具有可能的治疗相关性的抗癌作用。 对雌激素的反应解离另外表明在雌激素相关疾病（例如经前综合征，子宫内膜异位症等）中的治疗应用; 嗜酸性粒细胞脱粒的抑制表明应用于与嗜酸性粒细胞相关的疾病（嗜酸性粒细胞综合征，过敏性和超敏反应性疾病）。

    ABELMOSCHUS MANIHOT MEDICUS FLOWER PERFUMED PRODUCT
    39.
    发明申请
    ABELMOSCHUS MANIHOT MEDICUS FLOWER PERFUMED PRODUCT 审中-公开
    ABELMOSCHUS MANIHOT MEDICUS花卉鲜花产品

    公开(公告)号：US20100239697A1

    公开(公告)日：2010-09-23

    申请号：US12739405

    申请日：2007-10-22

    申请人： Zhiyuan Wang ,  Shaozhang Wang

    发明人： Zhiyuan Wang ,  Shaozhang Wang

    IPC分类号： A61K36/18 ,  A61P43/00 ,  A61K8/97 ,  A61Q5/00 ,  A61Q19/00 ,  A01N3/02 ,  A23L1/30

    CPC分类号： A61K36/185 ,  A23L33/105

    摘要： The Abelmoschus manihot Medicus flower perfumed product, which is made by immersing the Abelmoschus manihot Medicus flower containing volatile substance in Abelmoschus manihot Medicus oil, vegetable oil with more than 60% unsaturated fatty acid or cosmetic base oil grade mineral oil. The product using the edible oil and fat as the carrier can be used as food materials and that using mineral oil as the carrier can be used as the raw materials of medicine, skin care and hair care products.

    摘要翻译： Abelmoschus manihot Medicus花香水产品是通过将含有挥发性物质的Abelmoschus manihot Medicus花浸入Abelmoschus manihot Medicus油，含有超过60％不饱和脂肪酸的植物油或化妆品基础油矿物油制成的。 以食用油脂为载体的产品，可作为食品原料使用，以矿物油为载体，可作为医药，护肤品，护发产品的原料。