公开(公告)号：US06579986B2

公开(公告)日：2003-06-17

申请号：US10134777

申请日：2002-04-29

申请人： Michael S. Allen ,  Ramiya H. Premchandran ,  Sou-Jen Chang ,  Stephen Condon ,  John A. DeMattei ,  Steven A. King ,  Lawrence Kolaczkowski ,  Sukumar Manna ,  Paul J. Nichols ,  Hemant H. Patel ,  Subhash R. Patel ,  Daniel J. Plata ,  Eric J. Stoner ,  Jien-Heh J. Tien ,  Steven J. Wittenberger

发明人： Michael S. Allen ,  Ramiya H. Premchandran ,  Sou-Jen Chang ,  Stephen Condon ,  John A. DeMattei ,  Steven A. King ,  Lawrence Kolaczkowski ,  Sukumar Manna ,  Paul J. Nichols ,  Hemant H. Patel ,  Subhash R. Patel ,  Daniel J. Plata ,  Eric J. Stoner ,  Jien-Heh J. Tien ,  Steven J. Wittenberger

IPC分类号： C07D21536

CPC分类号： C07D215/14 ,  C07C68/06 ,  C07C69/96

摘要： The invention relates to a process for preparing quinoline-substituted carbonate and carbamate compounds, which are important intermediates in the synthesis of 6-O-substituted macrolide antibiotics. The process employs metal-catalyzed coupling reactions to provide a carbonate or carbamate of formula (I) or (II) or a substrate that can be reduced to obtain the same.

公开(公告)号：US6068372A

公开(公告)日：2000-05-30

申请号：US961813

申请日：1997-10-31

申请人： Gerard H. Rousseau ,  David W. Johnson ,  Richard Brzezinski ,  Jeffrey R. Kohne ,  Michael S. Allen ,  Brent R. Jones ,  Larry E. Hindman

发明人： Gerard H. Rousseau ,  David W. Johnson ,  Richard Brzezinski ,  Jeffrey R. Kohne ,  Michael S. Allen ,  Brent R. Jones ,  Larry E. Hindman

IPC分类号： B41J2/01 ,  B41J2/005 ,  B41J2/175 ,  G03G15/00

CPC分类号： G03G15/553 ,  B41J2/005 ,  G03G15/55

摘要： An improved replaceable liquid application system for applying a liquid intermediate transfer surface to a support surface in a printer is provided. The liquid application system is contained in a removable cassette and utilizes a liquid impregnated arcuate surface that engages the support surface by rolling contact. The liquid impregnated arcuate surface and a reclamation assembly are contained in a removable cartridge in the cassette. A cartridge life status assembly determines when the useful life of the cartridge has been exhausted. Push tabs on the cartridge and finger wells on the cassette allow for easy and convenient removal of a used cartridge and insertion of a replacement cartridge.

摘要翻译： 提供了一种用于将液体中间转印表面施加到打印机中的支撑表面的改进的可替换液体施加系统。 液体施加系统被包含在可拆卸的盒中并且利用通过滚动接触与支撑表面接合的液体浸渍的弧形表面。 液体浸渍的弧形表面和回收组件被包含在盒中的可移除的盒中。 墨盒寿命状态组件确定墨盒的使用寿命何时耗尽。 推动墨盒上的卡舌和墨盒上的指孔可轻松方便地取出旧墨盒并插入更换墨盒。

公开(公告)号：US5959118A

公开(公告)日：1999-09-28

申请号：US921399

申请日：1997-08-29

申请人： Michael S. Allen

发明人： Michael S. Allen

IPC分类号： C07D277/20 ,  C07D277/22 ,  C07D277/24 ,  C07D277/32

CPC分类号： C07D277/22 ,  C07D277/24 ,  C07D277/32

摘要： The present invention discloses a process for the preparation of a hydroxymethylthiazole compound having formula 3: The process of the invention comprises reacting a halomethyl thiazole having the formula: ##STR1## with water, at an elevated temperature. Optionally, the reaction can be carried out in the presence of a base, such as sodium carbonate, which can react with any acid formed. In the process of the invention, X is a halogen atom; and R.sup.6 is selected from the group consisting of hydrogen, and halogen atoms. The invention also contemplates the preparation of acid addition salts of the hydroxymethylthiazole, compound 3.

摘要翻译： 本发明公开了一种制备具有式3的羟甲基噻唑化合物的方法：本发明的方法包括使具有下式的卤代甲基噻唑与水在升高的温度下反应。 任选地，反应可以在诸如碳酸钠的碱的存在下进行，所述碱可以与任何形成的酸反应。 在本发明的方法中，X是卤素原子; 并且R 6选自氢和卤素原子。 本发明还考虑了羟甲基噻唑化合物3的酸加成盐的制备。

公开(公告)号：US5603057A

公开(公告)日：1997-02-11

申请号：US560504

申请日：1995-11-17

申请人： Michael S. Allen ,  Yoanna Baumgartner ,  Michael J. Garcia ,  Charles R. Moore ,  Robert J. Reese

发明人： Michael S. Allen ,  Yoanna Baumgartner ,  Michael J. Garcia ,  Charles R. Moore ,  Robert J. Reese

IPC分类号： G06F13/42 ,  G06F13/00

CPC分类号： G06F13/4217

摘要： A method and system in a data processing system for transferring data from a first device to a second device within the data processing system. The data processing system includes a data bus, an address bus, a first address space associated with a memory and a second address space associated with an input/output device. Initially, a transfer signal is transmitted in the data processing system. The transfer signal identifies the transfer as a transfer concerning an address in the second address space associated with the input/output device. A first address package is then transmitted to the second device from the first device on the address bus. The first address package includes a transfer identifier, a first identifier associated with the first device and a second identifier associated with the second device. A second address package, comprising a byte count and an address, are transmitted to the second device from the first device on the address bus. If data is to be transferred, the data is then transferred on the data bus. Finally, a reply signal may be transmitted between the first and second devices, acknowledging the success or failure of the data transfer.

摘要翻译： 一种用于在数据处理系统内将数据从第一设备传送到第二设备的数据处理系统中的方法和系统。 数据处理系统包括数据总线，地址总线，与存储器相关联的第一地址空间和与输入/输出设备相关联的第二地址空间。 最初，在数据处理系统中传送传送信号。 传送信号将传送标识为关于与输入/输出设备相关联的第二地址空间中的地址的传送。 然后，第一地址包从地址总线上的第一设备发送到第二设备。 第一地址包包括传送标识符，与第一设备相关联的第一标识符和与第二设备相关联的第二标识符。 包括字节计数和地址的第二地址包从地址总线上的第一设备发送到第二设备。 如果要传输数据，则数据在数据总线上传输。 最后，可以在第一和第二设备之间传送应答信号，确认数据传输的成功或失败。

公开(公告)号：US5541328A

公开(公告)日：1996-07-30

申请号：US415385

申请日：1995-04-03

申请人： Timothy L. Stuk ,  Michael S. Allen ,  Anthony R. Haight ,  Francis A. Kerdesky ,  Denton C. Langridge ,  M. Robert Leanna ,  Linda M. Lijewski ,  Laura Melcher ,  Howard E. Morton ,  Daniel W. Norbeck ,  Daniel S. Reno ,  Timothy A. Robbins ,  Hing L. Sham ,  Thomas J. Sowin ,  Jien-Heh J. Tien ,  Chen Zhao ,  David Scarpetti

发明人： Timothy L. Stuk ,  Michael S. Allen ,  Anthony R. Haight ,  Francis A. Kerdesky ,  Denton C. Langridge ,  M. Robert Leanna ,  Linda M. Lijewski ,  Laura Melcher ,  Howard E. Morton ,  Daniel W. Norbeck ,  Daniel S. Reno ,  Timothy A. Robbins ,  Hing L. Sham ,  Thomas J. Sowin ,  Jien-Heh J. Tien ,  Chen Zhao ,  David Scarpetti

IPC分类号： C07C213/00 ,  C07C215/28 ,  C07C225/16 ,  C07C227/18 ,  C07C229/36 ,  C07C231/12 ,  C07C233/35 ,  C07C251/40 ,  C07C255/27 ,  C07C255/42 ,  C07C269/06 ,  C07C271/20 ,  C07D209/44 ,  C07D221/14 ,  C07C251/78 ,  C07C209/44 ,  C07C221/14

CPC分类号： C07D221/14 ,  C07C213/00 ,  C07C215/28 ,  C07C225/16 ,  C07C251/40 ,  C07C255/42 ,  C07C269/06 ,  C07C271/20 ,  C07D209/44 ,  C07B2200/07

摘要： A substantially pure compound of formula: ##STR1## wherein R.sub.6 and R.sub.7 are independently selected from ##STR2## wherein R.sub.a and R.sub.b are independently selected from hydrogen, loweralkyl and phenyl and R.sub.c, R.sub.d and R.sub.e are independently selected from hydrogen, loweralkyl, trifluoromethyl, alkoxy, halo and phenyl; and ##STR3## wherein the naphthyl ring is unsubstituted or substituted with one, two or three substitutents independently selected from loweralkyl, trifluoromethyl, alkoxy and halo; orR.sub.6 is as defined above and R.sub.7 is R.sub.7a OC(O)-- wherein R.sub.7a is loweralkyl; orR.sub.6 and R.sub.7 taken together with the nitrogen atom to which they are bonded are ##STR4## wherein R.sub.f, R.sub.g, R.sub.h and R.sub.l are independently selected from hydrogen, loweralkyl, alkoxy, halogen and trifluoromethyl; andR.sub.g is hydrogen, loweralkyl or benzyl; or an acid addition salt thereof.

摘要翻译： （I）其中R a和R b独立地选自氢，低级烷基和苯基，R c，R d和R 10独立地选自氢，低级烷基 ，三氟甲基，烷氧基，卤素和苯基; （ii）其中萘基环是未取代的或被一个，两个或三个独立地选自低级烷基，三氟甲基，烷氧基和卤素的取代基取代; 或R 6如上所定义，且R 7为R 7aa（O） - ，其中R 7a为低级烷基; 或者R 6和R 7与它们所键合的氮原子一起是其中R f，R g，R h和R 1独立地选自氢，低级烷基，烷氧基，卤素和三氟甲基; R g为氢，低级烷基或苄基; 或其酸加成盐。