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公开(公告)号：US07806839B2
公开(公告)日：2010-10-05
申请号：US10867170
申请日：2004-06-14
CPC分类号： A61N7/022 , A61N2007/0065 , A61N2007/0078 , A61N2007/0095 , A61N2007/027
摘要： A system and method for medical treatment of tissue using ultrasound. The system comprises a probe having an array of transducer elements, an ultrasound waveform generator adapted to generate at least one electrical ultrasound signal, and a plurality of phase controls, each coupled to the ultrasound waveform generator and adapted to generate from the electrical ultrasound signal a phase-shifted drive signal that is coupled to an associated transducer element. The drive signal is effective to control grating lobe foci emitted by the array. The method employs the system.
摘要翻译： 一种使用超声波治疗组织的系统和方法。 该系统包括具有换能器元件阵列的探头，适于产生至少一个电超声波信号的超声波波形发生器，以及多个相位控制器，每个相位控制器耦合到超声波波形发生器，并适于从电超声波信号 耦合到相关联的换能器元件的相移驱动信号。 驱动信号有效地控制由阵列发射的光栅叶片焦点。 该方法采用该系统。
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公开(公告)号：US07758524B2
公开(公告)日：2010-07-20
申请号：US11245999
申请日：2005-10-06
IPC分类号： A61H1/00
CPC分类号： A61B17/320068 , A61B8/00 , A61H23/0245 , A61N7/02 , A61N2007/0034 , A61N2007/0052
摘要： A non-invasive ultra-high frequency ultrasound treatment method and system are provided. An exemplary method and system comprise a high-frequency ultrasound transducer system configured for providing ultrasound treatment to a patient such that the superficial and/or subcutaneous regions of the patient can be treated. An exemplary high-frequency ultrasound transducer system comprises a control system and a transducer configured to provide treatment to the superficial and/or subcutaneous regions of interest. The high-frequency ultrasound transducer may be configured to operate at higher frequencies and controlled power levels to provide treatment to the superficial and/or subcutaneous regions of interest. For example, higher frequencies within the range from approximately 20 MHz to 500 MHz or more may be utilized.
摘要翻译： 提供了非侵入式超高频超声处理方法和系统。 示例性方法和系统包括被配置为向患者提供超声治疗使得可以治疗患者的浅表和/或皮下区域的高频超声换能器系统。 示例性的高频超声换能器系统包括控制系统和被配置为向感兴趣的表面和/或皮下区域提供治疗的换能器。 高频超声换能器可以被配置为在更高的频率和受控的功率水平下操作以对感兴趣的表面和/或皮下区域提供治疗。 例如，可以使用在大约20MHz至500MHz或更大的范围内的较高频率。
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公开(公告)号：US20090216159A1
公开(公告)日：2009-08-27
申请号：US12437726
申请日：2009-05-08
CPC分类号： A61H23/0245 , A61B8/4472 , A61B8/483 , A61H2201/5007 , A61N7/00 , A61N7/02 , A61N2007/0008 , A61N2007/0073 , A61N2007/0078
摘要： A non-invasive method and system for combined ultrasound treatment are provided. An exemplary combined ultrasound treatment system comprises a transducer configured to deliver ultrasound energy to provide two or more energy effects to a region of interest. The energy effects facilitate the initiation of one or more responses in the region of interest. In accordance with an exemplary embodiment of the present invention, a transducer is configured to deliver energy over varying temporal and/or spatial distributions in order to provide energy effects and initiate responses in a region of interest.
摘要翻译： 提供了一种用于组合超声治疗的非侵入性方法和系统。 示例性组合超声治疗系统包括被配置为递送超声能量以向感兴趣区域提供两个或更多个能量效应的换能器。 能量效应有助于在感兴趣的区域启动一个或多个反应。 根据本发明的示例性实施例，换能器被配置为在不同的时间和/或空间分布上传递能量，以便在感兴趣的区域中提供能量效应并启动响应。
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公开(公告)号：US07473250B2
公开(公告)日：2009-01-06
申请号：US10850984
申请日：2004-05-21
申请人： Inder Raj S. Makin , T. Douglas Mast , Michael H. Slayton , Peter G. Barthe , Jeffrey D. Messerly , Waseem Faidi , Megan M. Runk , Brian D. O'Connor , Christopher J. Park , Paul M. Jaeger
发明人： Inder Raj S. Makin , T. Douglas Mast , Michael H. Slayton , Peter G. Barthe , Jeffrey D. Messerly , Waseem Faidi , Megan M. Runk , Brian D. O'Connor , Christopher J. Park , Paul M. Jaeger
IPC分类号： A61B18/18
CPC分类号： A61B5/4836 , A61B5/053 , A61B8/13 , A61B8/4281 , A61B8/4483 , A61B17/2202 , A61B18/06 , A61B18/08 , A61B18/12 , A61B18/1815 , A61B2090/378 , A61N7/00
摘要： An ultrasound medical system includes an interstitial end effector. The interstitial end effector is interstitially insertable into patient tissue, includes at least one medical-treatment ultrasound transducer, and includes at least one end-effector-tissue-track ablation device. One method for ultrasonically treating a lesion in a patient includes the steps of obtaining the interstitial end effector and inserting it into the patient creating a tissue track which is surrounded by patient tissue and which ends at the distal end of the inserted interstitial end effector. Other steps include ultrasonically ablating the lesion using the at-least-one medical-treatment ultrasound transducer, using the at-least-one end-effector-tissue-track ablation device to ablate the patient tissue surrounding the tissue track along substantially the entire tissue track, and withdrawing the end effector from the patient.
摘要翻译： 超声波医疗系统包括间质末端执行器。 间质末端效应器在间质中可插入患者组织中，包括至少一个医疗超声换能器，并且包括至少一个末端效应器 - 组织 - 轨道消融装置。 用于超声治疗患者病变的一种方法包括以下步骤：获得间隙末端执行器并将其插入患者中，从而产生组织轨迹，所述组织轨道被患者组织包围，并且在组织轨迹的末端处被插入插入的末端执行器。 其他步骤包括使用至少一个医疗超声换能器超声波消融损伤，使用至少一个末端效应器 - 组织道消融装置沿着基本上整个组织消融围绕组织轨迹的患者组织 跟踪并从患者中取出末端执行器。
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35.发明申请ULTRASOUND SYSTEM AND METHOD FOR IMAGING AND/OR MEASURING DISPLACEMENT OF MOVING TISSUE AND FLUID 有权用于成像和/或测量移动组织和流体位移的超声系统和方法公开(公告)号：US20080086054A1
公开(公告)日：2008-04-10
申请号：US11538794
申请日：2006-10-04
IPC分类号： A61B8/00
CPC分类号： A61B8/5207 , A61B8/06 , A61B8/08 , A61B8/13 , A61B8/14 , A61B8/4411 , A61B8/4483 , A61B8/461 , A61B8/488
摘要： A system and method for improved imaging is disclosed. An exemplary system provides a peripheral ultrasound system connected to a host computer with a plug-and-play interface such as a USB. An exemplary system utilizes a dedicated graphics processing unit such as a graphics card to analyze data obtained from a region of interest to produce an image on one or more output units for the user's viewing. Based on the image displayed on the output units, the user can determine the velocity of the moving tissue and fluid. The system of the present invention can be used to produce a Doppler color flow map or for power Doppler imaging.
摘要翻译： 公开了一种用于改进成像的系统和方法。 一个示例性系统提供了连接到主计算机的外围超声系统，其具有诸如USB的即插即用接口。 示例性系统利用诸如图形卡的专用图形处理单元来分析从感兴趣区域获得的数据，以在用于观看的一个或多个输出单元上产生图像。 基于显示在输出单元上的图像，用户可以确定移动的组织和流体的速度。 本发明的系统可用于产生多普勒彩色流图或功率多普勒成像。
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公开(公告)号：US07229411B2
公开(公告)日：2007-06-12
申请号：US10193419
申请日：2002-07-10
IPC分类号： A61B8/00
CPC分类号： A61N7/02 , A61B5/01 , A61B5/015 , A61B5/4836 , A61B8/0833 , A61B8/15 , A61B8/5223 , A61B2017/22028
摘要： An ultrasonic system useful for providing imaging, therapy and temperature monitoring generally comprises an acoustic transducer assembly configured to enable the ultrasound system to perform the imaging, therapy and temperature monitoring functions. The acoustic transducer assembly comprises a single transducer that is operatively connected to an imaging subsystem, a therapy subsystem and a temperature monitoring subsystem. The ultrasound system may also include a display for imaging and temperature monitoring functions. An exemplary single transducer is configured such that when connected to the subsystems, the imaging subsystem can generate an image of a treatment region on the display, the therapy subsystem can generate high power acoustic energy to heat the treatment region, and the temperature monitoring subsystem can map and monitor the temperature of the treatment region and display the temperature on the display, all through the use of the single transducer. Additionally, the acoustic transducer assembly can be configured to provide three-dimensional imaging, temperature monitoring or therapeutic heating through the use of adaptive algorithms and/or rotational or translational movement. Moreover, a plurality of the exemplary single transducers can be provided to facilitate enhanced treatment capabilities.
摘要翻译： 用于提供成像，治疗和温度监测的超声系统通常包括声学换能器组件，其被配置为使超声系统能够执行成像，治疗和温度监测功能。 声换能器组件包括可操作地连接到成像子系统，治疗子系统和温度监控子系统的单个换能器。 超声系统还可以包括用于成像和温度监视功能的显示器。 示例性的单个换能器被配置为使得当连接到子系统时，成像子系统可以在显示器上产生治疗区域的图像，治疗子系统可以产生高功率声能来加热治疗区域，并且温度监测子系统可以 映射和监控处理区域的温度，并通过使用单个传感器显示显示器上的温度。 此外，声换能器组件可以被配置为通过使用自适应算法和/或旋转或平移运动来提供三维成像，温度监测或治疗加热。 此外，可以提供多个示例性的单个换能器以便于增强的治疗能力。
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公开(公告)号：US6049159A
公开(公告)日：2000-04-11
申请号：US944261
申请日：1997-10-06
CPC分类号： B06B1/0681 , G10K11/02
摘要： A transducer according to various aspects of the present invention provides high fractional bandwidth with relatively low degradation of the pulse duration and sensitivity. The transducer includes a back matching layer behind the transducer material. The back matching layer is characterized by an impedance selected to transmit a selected portion of the backwards propagating acoustic energy to an absorption layer. The remaining acoustic energy is reflected in the desired direction of propagation. As a result, the transducer provides enhanced bandwidth without excessive loss of sensitivity or increase in pulse duration.
摘要翻译： 根据本发明的各个方面的换能器提供了高分数带宽，脉冲持续时间和灵敏度的降低相对较低。 换能器包括在换能器材料后面的背部匹配层。 背部匹配层的特征在于阻抗被选择以将向后传播的声能的选定部分传输到吸收层。 剩余的声能被反射在期望的传播方向上。 因此，传感器提供增强的带宽，而不会过多的灵敏度损失或脉冲持续时间的增加。
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38.发明申请Methods and Systems for Coupling and Focusing Acoustic Energy Using a Coupler Member 审中-公开使用耦合器构件耦合和聚焦声能的方法和系统公开(公告)号：US20150005638A1
公开(公告)日：2015-01-01
申请号：US14321682
申请日：2014-07-01
摘要： An exemplary system for coupling acoustic energy using an encapsulated coupler member comprises a display or indicator, a control system, a probe, and a coupler member. This invention provides a coupler member adjustably configured to perform at least one of (i) providing a standoff, (ii) focusing or defocusing energy, and (iii) coupling energy. An exemplary gel coupler member is configured to hold the shape of a lens geometry. In one aspect of the present invention, gel coupler member comprises water, glycerol, and polyvinyl alcohol, and exhibits an increased desiccation time and shelf life when compared to the prior art. The probe can comprise various probe and/or transducer configurations. In an exemplary embodiment, the probe delivers focused, unfocused, and/or defocused ultrasound energy to the region of interest. Imaging and/or monitoring may alternatively be coupled and/or co-housed with an ultrasound system contemplated by the present invention.
摘要翻译： 使用封装的耦合器部件耦合声能的示例性系统包括显示器或指示器，控制系统，探针和耦合器部件。 本发明提供一种可调节地配置成执行（i）提供支座，（ii）聚焦或散焦能量和（iii）耦合能量中的至少一个的耦合器部件。 示例性的凝胶耦合器构件被配置为保持透镜几何形状。 在本发明的一个方面，凝胶偶联剂包含水，甘油和聚乙烯醇，并且与现有技术相比表现出增加的干燥时间和保存期限。 探头可以包括各种探头和/或换能器构造。 在示例性实施例中，探针将聚焦的，未聚焦的和/或散焦的超声能量传递到感兴趣的区域。 可以与本发明预期的超声系统可以联接和/或共同成像和/或监视。
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39.发明申请Methods and Systems for Generating Thermal Bubbles for Improved Ultrasound Imaging and Therapy 有权用于产生热气泡以改善超声成像和治疗的方法和系统公开(公告)号：US20140243713A1
公开(公告)日：2014-08-28
申请号：US14270859
申请日：2014-05-06
IPC分类号： A61N7/00
CPC分类号： A61N7/00 , A61B8/4281 , A61B8/4472 , A61B8/48 , A61B2018/00005 , A61B2018/00642 , A61N5/0616 , A61N5/10 , A61N2007/0039 , A61N2007/0043 , A61N2007/0056 , A61N2007/006 , A61N2007/0065 , A61N2007/0073
摘要： A method and system uniquely capable of generating thermal bubbles for improved ultrasound imaging and therapy. Several embodiments of the method and system contemplates the use of unfocused, focused, or defocused acoustic energy at variable spatial and/or temporal energy settings, in the range of about 1 kHz-100 MHz, and at variable tissue depths. The unique ability to customize acoustic energy output and target a particular region of interest makes possible highly accurate and precise thermal bubble formation. In an embodiment, the energy is acoustic energy. In other embodiments, the energy is photon based energy (e.g., IPL, LED, laser, white light, etc.), or other energy forms, such radio frequency electric currents (including monopolar and bipolar radio-frequency current). In an embodiment, the energy is various combinations of acoustic energy, electromagnetic energy and other energy forms or energy absorbers such as cooling.
摘要翻译： 一种独特地产生热气泡以改进超声成像和治疗的方法和系统。 该方法和系统的几个实施例考虑在约1kHz-100MHz的范围内和在可变组织深度处的可变空间和/或时间能量设置下使用未聚焦，聚焦或散焦的声能。 定制声能输出和瞄准特定感兴趣区域的独特能力使得高精度和精确的热气泡形成成为可能。 在一个实施例中，能量是声能。 在其他实施例中，能量是基于光子的能量（例如，IPL，LED，激光，白光等）或其他能量形式，例如射频电流（包括单极性和双极性射频电流）。 在一个实施例中，能量是声能，电磁能和其它能量形式或诸如冷却的能量吸收器的各种组合。
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40.发明授权Methods and systems for generating thermal bubbles for improved ultrasound imaging and therapy 有权用于产生热气泡以改善超声成像和治疗的方法和系统公开(公告)号：US08715186B2
公开(公告)日：2014-05-06
申请号：US12954484
申请日：2010-11-24
IPC分类号： A61B8/00
CPC分类号： A61N7/00 , A61B8/4281 , A61B8/4472 , A61B8/48 , A61B2018/00005 , A61B2018/00642 , A61N5/0616 , A61N5/10 , A61N2007/0039 , A61N2007/0043 , A61N2007/0056 , A61N2007/006 , A61N2007/0065 , A61N2007/0073
摘要： A method and system uniquely capable of generating thermal bubbles for improved ultrasound imaging and therapy. Several embodiments of the method and system contemplates the use of unfocused, focused, or defocused acoustic energy at variable spatial and/or temporal energy settings, in the range of about 1 kHz-100 MHz, and at variable tissue depths. The unique ability to customize acoustic energy output and target a particular region of interest makes possible highly accurate and precise thermal bubble formation. In an embodiment, the energy is acoustic energy. In other embodiments, the energy is photon based energy (e.g., IPL, LED, laser, white light, etc.), or other energy forms, such radio frequency electric currents (including monopolar and bipolar radio-frequency current). In an embodiment, the energy is various combinations of acoustic energy, electromagnetic energy and other energy forms or energy absorbers such as cooling.
摘要翻译： 一种独特地产生热气泡以改进超声成像和治疗的方法和系统。 该方法和系统的几个实施例考虑在约1kHz-100MHz的范围内和在可变组织深度处的可变空间和/或时间能量设置下使用未聚焦，聚焦或散焦的声能。 定制声能输出和瞄准特定感兴趣区域的独特能力使得高精度和精确的热气泡形成成为可能。 在一个实施例中，能量是声能。 在其他实施例中，能量是基于光子的能量（例如，IPL，LED，激光，白光等）或其他能量形式，例如射频电流（包括单极性和双极性射频电流）。 在一个实施例中，能量是声能，电磁能和其它能量形式或诸如冷却的能量吸收器的各种组合。
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