Abstract:
A process for the isolation of cyclosporin A comprising the steps of: adding a lower alkanol solvent to a culture fluid of a mutant of Tolypocladium inflatum to form a mixture, filtering the mixture to form an extract, transferring the extract to methylene chloride as a solvent therefor, and column chromatographing the resultant product on silica gel.
Abstract:
The present invention relates to a process for making a highly productive fusant of Tolypocladium inflatum, a producing strain of cyclosporin A with immunosuppressive properties wherein the selection of the fusant KD461, designed to produce a large amount of cyclosporin A, was made available by the following steps of: developing amino acid-dependent mutants of Tolypocladium inflatum, wild strain isolated from soil, which mutants are induced by UV radiation; conjugating L-valine-dependent and L-leucine-dependent mutants to promote the demand and utility of L-valine and L-leucine, precursors of cyclosporin A, together with an organic nitrogen-source. The fusant KD461 produced has the following characteristics in comparison with wild strain: 1) it is slow growing in a solid malt-yeast extract agar medium, b) the surface of the colony is light grey in color and is therefore darker than the mild strain, c) the backside of the colony is dark brown, and d) in a liquid medium it has short and thick hyphae with many arthrospore.
Abstract:
According to the present invention, a process for manufacturing alkali metal salt of clavulanic acid wherein impure clavulanic acid in aqueous solution is extracted by a solvent mixture of ketone and alkyl acetate under acidic condition, treated in a conventional manner, and a solution of alkali metal salt of alkanoic acid dissolved in ketone or alkanol solvent is added to obtain pure alkali metal salt of clavulanic acid is provided. Since the process according to the present invention omits a step of formation of amine salt, an economic and simple method for manufacturing alkali metal salt of clavulanic acid in a high yield without excessive use of solvent is provided.
Abstract:
A multi-touch sensing display apparatus is provided. The multi-touch sensing display apparatus may include a back light unit, a display panel, a sensor unit on a display surface of the display panel, and a touch light source unit providing light to be diffused by a touch of a user so that the sensor unit senses the touch of the user. The touch light source unit may include a touch light source and a transparent light guide plate. The transparent light guide plate may include a light guiding unit and a plurality of light emitting units integrally formed with each other as a single body, wherein the light guiding unit guides light from the touch light source to an inside thereof, and the plurality of light emitting units protrudes from the light guiding unit and emits light from the light guiding unit.
Abstract:
This disclosure relates to magenta polymerized toner comprising magenta pigment selected from quinacridone-based derivatives and magenta pigment selected from diketo-pyrrolopyrrole derivatives, having high transfer efficiency, high image density, and uniform particle distribution.
Abstract:
A touch screen apparatus including: a touch sensing unit; a memory configured to store sensing information transmitted from the touch sensing unit; and a display unit associated with the memory, the display unit configured to receive and display the sensing information stored in the memory.
Abstract:
A method and apparatus for decoding hierarchical mode information including mode information indicating whether a current block is encoded in an encoding mode identical to an encoding mode of a plurality of consecutive previous blocks.
Abstract:
A foldable display device is designed so that a junction between at least two display panels connected to each other is not visibly seen. The display device displays an image on a plurality of display panels that are connected together. Pixels near the junction between every two adjacent display panels of the at least two display panels are smaller and have a higher brightness than the other pixels.
Abstract:
A pixel of a display apparatus includes at least a first transistor and at least a second transistor. A cell of transparent fluid including particles charged to have different polarities from each other is arranged between a pixel electrode and a common electrode. The first and second transistors are connected to the pixel electrode. The pixel is drivable according to pulse amplitude modulation (PAM) and pulse width modulation (PWM) such that a frame of an image is displayable using a single field.
Abstract:
Example embodiments include an RFID display pixel, and a display panel and a display apparatus using the RFID display pixel. The RFID display pixel includes an RFID tag having an antenna and an IC chip; and a display device connected to the RFID tag. The display device is driven according to information received from the antenna. The display apparatus includes a display panel having a two-dimensional array of a plurality of RFID display pixels having the RFID tag and display device. An image control unit generates an image signal to be displayed on the display panel and an RFID reading unit wirelessly communicates with the RFID tag and transmits the image signal generated in the image control unit to the RFID tag.