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    Electric Pipetting Apparatus, and Method for Operating an Electric Pipetting Apparatus
    32.
    发明申请
    Electric Pipetting Apparatus, and Method for Operating an Electric Pipetting Apparatus 审中-公开
    电动移液器及其操作方法

    公开(公告)号：US20130288382A1

    公开(公告)日：2013-10-31

    申请号：US13847941

    申请日：2013-03-20

    Applicant: Eppendorf AG

    Inventor： Karl-Friedrich ANDRES ,  Janine JACOBI ,  Peter MOLITOR ,  Peter SCHMIDT

    IPC: B01L3/02

    CPC classification number: B01L3/021 ,  B01L3/0237 ,  B01L2200/087 ,  B01L2200/14 ,  B01L2300/024 ,  B01L2300/027 ,  G01N2035/1039 ,  Y10T436/2575

    Abstract: The invention relates to a pipetting apparatus, for pipetting a fluid sample in accordance with at least one mode of operation of the pipetting apparatus, which is controlled by an operating parameter set, which is associated with a corresponding mode of operation, wherein the electric control device of the pipetting apparatus is designed to automatically store the at least one parameter value set determined by the user to be the at least one historic parameter value set for this mode of operation in the memory device, and is designed to provide, after the operating parameter set for this mode of operation has changed, the at least one automatically stored historic parameter value set for this mode of operation again for the subsequent control of the at least one, same, pipetting process. The invention also relates to a method for operating the pipetting apparatus.

    Abstract translation: 本发明涉及一种移液装置，其用于根据移动装置的至少一种操作模式来吸取流体样品，该操作模式由与相应操作模式相关联的操作参数组控制，其中电控制 移液装置的设备被设计成将由用户确定的至少一个参数值集合自动存储为存储装置中为该操作模式设置的至少一个历史参数值，并且被设计成在操作之后提供 为此操作模式的参数设置已经改变，为该操作模式设置的至少一个自动存储的历史参数值再次用于随后控制至少一个相同的移液过程。 本发明还涉及一种操作移液装置的方法。

    Method and compositions for reversible inhibition of thermostable polymerases
    33.
    发明申请
    Method and compositions for reversible inhibition of thermostable polymerases 审中-公开
    用于可逆抑制热稳定聚合酶的方法和组合物

    公开(公告)号：US20040077008A1

    公开(公告)日：2004-04-22

    申请号：US10661428

    申请日：2003-09-11

    Applicant: Eppendorf AG

    Inventor： Lars-Erik Peters

    IPC: C12Q001/68 ,  C12P019/34

    CPC classification number: C12N15/72 ,  C12N9/1252 ,  C12Q1/6848 ,  C12Q2527/127 ,  C12Q2527/125 ,  C12Q2527/101

    Abstract: Methods for improving sensitivity and specificity of polynucleotide synthesis are disclosed. The method includes reversibly blocking thermophilic polymerase activity with non-nucleic acid polyanions in a temperature dependent manner. The methods control target specific primer extension throughout all stages of a DNA or RNA amplification reaction. Corresponding compositions and kits are disclosed.

    Abstract translation: 公开了提高多核苷酸合成的灵敏度和特异性的方法。 该方法包括以温度依赖性方式用非核酸聚阴离子可逆地阻断嗜热聚合酶活性。 该方法控制DNA或RNA扩增反应的所有阶段的靶标特异性引物延伸。 公开了相应的组合物和试剂盒。

    Electronic laboratory metering system for liquids and method for operating an electronic laboratory metering system for liquids
    34.
    发明授权
    Electronic laboratory metering system for liquids and method for operating an electronic laboratory metering system for liquids 有权

    公开(公告)号：US12112846B2

    公开(公告)日：2024-10-08

    申请号：US16981011

    申请日：2019-03-12

    Applicant: Eppendorf AG

    Inventor： Jan-Hendrik Hacker ,  Peter Molitor

    IPC: G16H40/67 ,  B01L3/02 ,  B01L9/00 ,  G01N35/10 ,  G16H10/40 ,  G16H40/20 ,  G16H40/40 ,  G16H70/20

    CPC classification number: G16H40/20 ,  B01L3/0293 ,  B01L9/54 ,  G01N35/1016 ,  G16H10/40 ,  G16H40/40 ,  G16H40/67 ,  G16H70/20 ,  B01L2200/143 ,  B01L2300/023 ,  G01N2035/1025

    Abstract: An electronic laboratory metering system for liquids includes an electrical hand-held metering device (2) having at least one operation sensor unit (5) that detects operation of the hand-held metering device (2) and generates operating data and stores same in a storage apparatus (6), wherein the hand-held metering device (2) has an interface module (7) for connecting the hand-held metering device (2) to an external network access apparatus (4) for transferring the operating data; the metering system (1), specifically a data processing system (3), has a comparison unit (9) to compare operating data with target operating data and/or to compare context parameter data from the context parameter sensor unit (8) with target context parameter data and to generate a comparison result. The metering system (1) includes a documentation unit (10) designed to generate and store log data records including at least the operating data and/or the context parameter data. The documentation unit (10) is connected to the comparison unit (9) to transmit the comparison results from the comparison unit (9) to the documentation unit (10) and the documentation unit (10) stores the comparison results as part of the log data records to be assigned to the relevant operating data and/or context parameter data, to add to same after operation of the hand-held metering device (2) has ended.

    Single-use connection device
    35.
    发明授权
    Single-use connection device 有权

    公开(公告)号：US11608484B2

    公开(公告)日：2023-03-21

    申请号：US16072630

    申请日：2017-01-27

    Applicant: EPPENDORF AG

    Inventor： Matthias Arnold ,  Sebastian Selzer ,  Sven Eikelmann ,  Jochen Beese

    IPC: C12M1/00 ,  C12M1/12 ,  C12M1/34 ,  C12M3/00

    Abstract: The invention relates to a single-use connection device for insertion into a connection opening of a bioreactor, in particular in a connection opening of a top plate of a dimensionally-stable bioreactor or in a connection opening of a connection element of a pouch bioreactor. The single-use connection device is inserted in a connection opening of a top plate of a bioreactor and/or in a connection opening of a pouch reactor and is provided with multiple passages and an attachment section, wherein the single-use connection device is formed as a single piece and is made of plastic. The attachment section, on an outer peripheral surface, has an attachment structure for attaching the single-use connection device in the connection opening.

    Pipette for use with a pipette tip
    36.
    发明授权
    Pipette for use with a pipette tip 有权

    公开(公告)号：US11554367B2

    公开(公告)日：2023-01-17

    申请号：US16735066

    申请日：2020-01-06

    Applicant: Eppendorf AG

    Inventor： Martin Seippel ,  Matthias Kunsch ,  Burkhardt Reichmuth ,  Tobias David ,  Frank Horstmann ,  Jens Wilmer ,  Marc Wilth

    IPC: B01L3/02 ,  B01L9/00

    Abstract: A pipette for use with a pipette tip includes a housing, a pin on the bottom end of the housing holding a pipette tip having first means for form-fit connection and a second means for form-fit connection which can be shoved onto the pin, constricting the pin, and/or expanding the tip before form-fit connection with the pin, a drive apparatus, at least one locking sleeve arranged concentric to the pin which is guided toward the pin in the housing, wherein the locking sleeve has a locked position having a pin in the inside constricted by shoving on a pipette tip, and/or is bordered on the outside by a tip shoved onto the pin, preventing a release from the pin, and the locking sleeve is upwardly displaceable out of the locked position so that the pin, and/or the tip is released, and the tip is removable from the pin.

    Fixed angle centrifuge rotor with stiffening rib
    37.
    发明授权
    Fixed angle centrifuge rotor with stiffening rib 有权

    公开(公告)号：US11498083B2

    公开(公告)日：2022-11-15

    申请号：US16541538

    申请日：2019-08-15

    Applicant: Eppendorf AG

    Inventor： Steffen Kühnert

    IPC: B04B7/08 ,  B04B5/04

    Abstract: A fixed-angle rotor for centrifuges includes stiffening ribs on the lower side of its rotor body. Its rotational energy is comparatively low during operation even at high speeds, whereby safety is noticeably increased without the need for a reinforced armored vessel in the centrifuge that is equipped therewith. At the same time, the drive power required to drive the fixed-angle rotor remains low. The fixed-angle rotor also withstands extreme loads over a long period of time. In addition, the fixed-angle rotor can be manufactured cost-effectively, because no additional components are required; rather, the stiffening ribs can also be manufactured during the manufacture of the rotor body. Finally, very thin rotor shells can also be used, which improves the temperature control of the samples, because the fixed-angle rotor has very good structural stability, especially in the main load directions.

    Pipetting device and method for producing same
    40.
    发明授权
    Pipetting device and method for producing same 有权

    公开(公告)号：US11338281B2

    公开(公告)日：2022-05-24

    申请号：US16065628

    申请日：2016-12-21

    Applicant: EPPENDORF AG

    Inventor： Holger Link ,  Tobias David ,  Hedda Merkens

    IPC: B01L3/02

    Abstract: The invention further relates to a method for producing said pipetting device. The invention relates to a pipetting device, in particular for pipetting a fluid sample by suctioning into a pipetting container using air under a pipetting pressure, having the following: —a valve assembly with at least one valve device for adjusting a pipetting pressure, said valve device having a valve chamber; —at least one pump device which is connected to the valve chamber in order to generate a chamber pressure in the valve chamber; —a pipetting channel which is connected to the pipetting container, and—a bypass channel which is open towards the surroundings, wherein—the pipetting channel and the bypass channel are each connected to the valve chamber; and—the at least one valve device has a closure element with a closure surface which is designed such that the chamber pressure is distributed to the pipetting channel and the bypass channel in a metered manner by the valve device in order to generate the desired pipetting pressure in the pipetting channel. The invention further relates to a method for producing said pipetting device.

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