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    X-RAY IMAGE FEATURE DETECTION AND REGISTRATION SYSTEMS AND METHODS
    22.
    发明申请
    X-RAY IMAGE FEATURE DETECTION AND REGISTRATION SYSTEMS AND METHODS 审中-公开

    公开(公告)号：US20170140531A1

    公开(公告)日：2017-05-18

    申请号：US15355970

    申请日：2016-11-18

    Applicant: LightLab Imaging, Inc.

    Inventor： Lorina Dascal ,  Itai Winkler

    IPC: G06T7/00

    CPC classification number: A61B6/5247 ,  A61B5/0066 ,  A61B6/504 ,  A61B8/12 ,  G06T5/50 ,  G06T7/0012 ,  G06T2207/10101 ,  G06T2207/10116 ,  G06T2207/30101

    Abstract: The disclosure relates generally to the field of vascular system and peripheral vascular system data collection, imaging, image processing and feature detection relating thereto. In part, the disclosure more specifically relates to methods for detecting position and size of contrast cloud in an x-ray image including with respect to a sequence of x-ray images during intravascular imaging. Methods of detecting and extracting metallic wires from x-ray images are also described herein such as guidewires used in coronary procedures. Further, methods for of registering vascular trees for one or more images, such as in sequences of x-ray images, are disclosed. In part, the disclosure relates to processing, tracking and registering angiography images and elements in such images. The registration can be performed relative to images from an intravascular imaging modality such as, for example, optical coherence tomography (OCT) or intravascular ultrasound (IVUS).

    Swept mode-hopping laser system, methods, and devices for frequency-domain optical coherence tomography
    24.
    发明授权
    Swept mode-hopping laser system, methods, and devices for frequency-domain optical coherence tomography 有权

    公开(公告)号：US09488464B1

    公开(公告)日：2016-11-08

    申请号：US14045537

    申请日：2013-10-03

    Applicant: Joseph M. Schmitt

    Inventor： Joseph M. Schmitt

    IPC: G01B9/02

    CPC classification number: G01B9/02091 ,  G01B9/02004 ,  G01B9/02069 ,  H01S3/1062 ,  H01S5/141

    Abstract: In part, the invention relates to frequency-domain optical coherence tomography system. The system includes a tunable laser comprising a laser output for transmitting laser light and a laser cavity having a length L, a gain element disposed within the laser cavity; a tunable wavelength selective element disposed within the laser cavity; a reference reflector disposed outside of the laser cavity; an interferometer in optical communication with the laser output and the reference reflector, wherein the interferometer is configured to transmit a portion of the laser light to a sample and combine light scattered from the sample with light scattered from the reference reflector; and a detector in optical communication with the interferometer that receives the combination of light scattered from the sample and the light scattered from the reference reflector and transforms the combination of light into an electronic signal comprising measurement data with respect to the sample.

    Methods and Apparatus for Swept-Source Optical Coherence Tomography
    26.
    发明申请
    Methods and Apparatus for Swept-Source Optical Coherence Tomography 有权
    扫描源光学相干断层扫描的方法和装置

    公开(公告)号：US20150192405A1

    公开(公告)日：2015-07-09

    申请号：US14535489

    申请日：2014-11-07

    Applicant: Joseph M. Schmitt

    Inventor： Joseph M. Schmitt

    IPC: G01B9/02

    CPC classification number: G01B9/02091 ,  A61B5/0066 ,  A61B5/0073 ,  G01B9/02004 ,  G01B9/02043 ,  G01B9/02069 ,  G01B2290/25 ,  G01B2290/60 ,  H01S3/1062 ,  H01S5/141 ,  H01S5/146 ,  H01S5/5036

    Abstract: In one embodiment of the invention, a semiconductor optical amplifier (SOA) in a laser ring is chosen to provide low polarization-dependent gain (PDG) and a booster semiconductor optical amplifier, outside of the ring, is chosen to provide high polarization-dependent gain. The use of a semiconductor optical amplifier with low polarization-dependent gain nearly eliminates variations in the polarization state of the light at the output of the laser, but does not eliminate the intra-sweep variations in the polarization state at the output of the laser, which can degrade the performance of the SS-OCT system.

    Abstract translation: 在本发明的一个实施例中，选择激光环中的半导体光放大器（SOA）以提供低偏振相关增益（PDG），并且选择在环外部的升压半导体光放大器以提供高偏振相关 获得。 使用具有低偏振相关增益的半导体光放大器几乎消除了在激光器的输出处的光的偏振状态的变化，但是不消除激光器的输出处的偏振状态的扫描内变化， 这可能会降低SS-OCT系统的性能。

    Controller and user interface device, systems, and methods
    27.
    发明授权
    Controller and user interface device, systems, and methods 有权
    控制器和用户界面设备，系统和方法

    公开(公告)号：US09069396B2

    公开(公告)日：2015-06-30

    申请号：US13798017

    申请日：2013-03-12

    Applicant: Desmond Adler ,  Joshua M. Gomes ,  David Winston ,  Susan Moynihan

    Inventor： Desmond Adler ,  Joshua M. Gomes ,  David Winston ,  Susan Moynihan

    IPC: G06F3/033 ,  G06F3/038 ,  G06F3/048 ,  G06F3/0489 ,  G06F3/0354 ,  G06F3/0338 ,  G05G9/047

    CPC classification number: G05B15/02 ,  G05G1/10 ,  G05G9/047 ,  G06F3/0338 ,  G06F3/0346 ,  G06F3/03543 ,  G06F3/038 ,  G06F3/048 ,  G06F3/04842 ,  G06F3/04845 ,  G06F3/04847 ,  G06F3/04892

    Abstract: A data collection system controller that includes a housing such as a cover. The housing includes a user facing section and a support facing section defining a hole. The controller also includes a first input device adjacent the user facing section and a second input device. The second input device includes a knob comprising a third input device and a rotatable shaft extending through the hole and partially disposed within the knob. In one embodiment, the second input device is an XYZ joystick with a button. In one embodiment, the joystick and the first input device are angled relative to each other on either side of an elbow joint. In part, the invention relates to a method of controlling the display of image data obtained with respect to a blood vessel.

    Abstract translation: 一种数据采集系统控制器，其包括诸如盖的壳体。 壳体包括面向用户的部分和限定孔的支撑面对部分。 控制器还包括与用户面对部分相邻的第一输入装置和第二输入装置。 第二输入装置包括旋钮，其包括第三输入装置和延伸穿过孔并部分地设置在旋钮内的旋转轴。 在一个实施例中，第二输入装置是具有按钮的XYZ操纵杆。 在一个实施例中，操纵杆和第一输入装置在肘关节的任一侧上相对于彼此成角度。 部分地，本发明涉及一种控制相对于血管获得的图像数据的显示的方法。

    Intensity noise reduction methods and apparatus for interferometric sensing and imaging systems
    28.
    发明授权
    Intensity noise reduction methods and apparatus for interferometric sensing and imaging systems 有权
    用于干涉测量和成像系统的强度降噪方法和装置

    公开(公告)号：US08948613B2

    公开(公告)日：2015-02-03

    申请号：US13050410

    申请日：2011-03-17

    Applicant: Joseph M. Schmitt ,  Victor Grinberg

    Inventor： Joseph M. Schmitt ,  Victor Grinberg

    IPC: H04B10/06 ,  G01B9/02 ,  H03G3/30 ,  H04B10/67

    CPC classification number: G01B9/02055 ,  G01B9/02004 ,  G01B9/02044 ,  G01B9/02074 ,  G01B9/02083 ,  H03G3/3084 ,  H04B10/616 ,  H04B10/671

    Abstract: In part, aspects of the invention relate to methods, apparatus, and systems for intensity and/or pattern line noise reduction in a data collection system such as an optical coherence tomography system that uses an electromagnetic radiation source and interferometric principles. In one embodiment, the noise is intensity noise or line pattern noise and the source is a laser such as a swept laser. One or more attenuators responsive to one or more control signals can be used in conjunction with an analog or digital feedback network in one embodiment.

    Abstract translation: 部分地，本发明的方面涉及数据采集系统中的强度和/或图案线噪声降低的方法，装置和系统，例如使用电磁辐射源和干涉原理的光学相干断层摄影系统。 在一个实施例中，噪声是强度噪声或线图案噪声，并且源是诸如扫描激光器的激光器。 在一个实施例中，响应于一个或多个控制信号的一个或多个衰减器可以与模拟或数字反馈网络结合使用。

    SYSTEMS, METHODS AND APPARATUS FOR DETERMINING A FRACTIONAL FLOW RESERVE
    29.
    发明申请
    SYSTEMS, METHODS AND APPARATUS FOR DETERMINING A FRACTIONAL FLOW RESERVE 审中-公开
    系统，方法和装置，用于确定一个流量流动储备

    公开(公告)号：US20140379269A1

    公开(公告)日：2014-12-25

    申请号：US14126152

    申请日：2012-08-01

    Applicant: Joseph Schmitt

    Inventor： Joseph Schmitt

    IPC: G01N21/85 ,  A61B5/02 ,  A61B5/00 ,  G01B9/02 ,  G01N21/47

    CPC classification number: G01N21/85 ,  A61B5/0066 ,  A61B5/0084 ,  A61B5/02007 ,  A61B5/02028 ,  A61B5/0215 ,  A61B5/4836 ,  A61B5/489 ,  A61B5/6852 ,  A61B34/10 ,  A61B2576/02 ,  G01B9/02091 ,  G01N21/4795

    Abstract: In one aspect, the invention relates to system comprising: a processor configured to receive a first optical coherence tomography (OCT) data set obtained during a pullback of a data collection probe along a first length of a first blood vessel; determine a minimum lumen area disposed along the first length using the first OCT data set; and determine a first FFR value along the first length based on the minimum lumen area. In one embodiment, the first FFR value is an estimated FFR. In another aspect, the invention relates to a method that includes measuring, using OCT, the area of a lumen of a vessel for which the vessel's FFR is to be determined; and calculating, using a computer, A2m/(A2m+k) or YA2min/(YA2min+k) as a FFR value. In one embodiment, k is about 0.7 mm2 and γ is patient-specific variable that depends on the coronary branch in which the images were obtained.

    Abstract translation: 一方面，本发明涉及一种系统，包括：处理器，被配置为接收沿着第一血管的第一长度在数据采集探头的回退期间获得的第一光学相干断层摄影（OCT）数据集; 使用所述第一OCT数据集来确定沿所述第一长度设置的最小流明面积; 并且基于最小管腔面积确定沿着第一长度的第一FFR值。 在一个实施例中，第一FFR值是估计的FFR。 在另一方面，本发明涉及一种方法，其包括使用OCT测量要确定所述血管的FFR的血管腔的面积; 并使用计算机计算A2m /（A2m + k）或YA2min /（YA2min + k）作为FFR值。 在一个实施方案中，k为约0.7mm 2，γ为取决于获得图像的冠状动脉分支的患者特异性变量。

    Lumen Morphology and Vascular Resistance Measurements Data Collection Systems, Apparatus and Methods
    30.
    发明申请
    Lumen Morphology and Vascular Resistance Measurements Data Collection Systems, Apparatus and Methods 审中-公开
    流明形态和血管阻力测量数据采集系统，装置和方法

    公开(公告)号：US20140276011A1

    公开(公告)日：2014-09-18

    申请号：US13796710

    申请日：2013-03-12

    Applicant: Joseph M. Schmitt ,  Joel M. Friedman ,  Christopher Petroff ,  Amr Elbasiony

    Inventor： Joseph M. Schmitt ,  Joel M. Friedman ,  Christopher Petroff ,  Amr Elbasiony

    IPC: A61B5/02 ,  A61B5/00

    CPC classification number: A61B5/02007 ,  A61B5/0066 ,  A61B5/0084

    Abstract: A method and apparatus of automatically locating in an image of a blood vessel the lumen boundary at a position in the vessel and from that measuring the diameter of the vessel. From the diameter of the vessel and estimate blood flow rate, a number of clinically significant physiological parameters are then determine and various user displays of interest generated. One use of these images and parameters is to aid the clinician in the placement of a stent. The system, in one embodiment, uses these measurements to allow the clinician to simulate the placement of a stent and to determine the effect of the placement. In addition, from these patient parameters various patient treatments are then performed.

    Abstract translation: 一种自动定位在血管图像中的管腔边界在容器中的位置以及从测量血管直径的方法和装置。 从容器的直径和估计血流速度，然后确定许多临床显着的生理参数，并且生成各种用户显示兴趣。 这些图像和参数的一个用途是帮助临床医生放置支架。 在一个实施例中，该系统使用这些测量来允许临床医生模拟支架的放置并确定放置的影响。 此外，从这些患者参数，然后执行各种患者治疗。

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