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公开(公告)号:USD815752S1
公开(公告)日:2018-04-17
申请号:US29510481
申请日:2014-11-28
Applicant: Randox Laboratories Ltd.
Designer: Stuart Jackson , Ivan McConnell , John Lamont , Peter Fitzgerald
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公开(公告)号:US20180011115A1
公开(公告)日:2018-01-11
申请号:US15547608
申请日:2016-01-29
Applicant: Randox Laboratories Ltd.
Inventor: Mark W. Ruddock , Cherith N. Reid , Kate E. Williamson , John Lamont , Peter Fitzgerald
IPC: G01N33/86
CPC classification number: G01N33/86 , G01N33/57407 , G01N33/6893 , G01N2800/50 , G01N2800/709
Abstract: The present invention related to a method for detecting a history of exposure to a chemical(s) comprising measuring the concentration of thrombomodulin in a sample isolated from a subject, and determining whether the concentration of thrombomodulin is altered compared to control reference levels.
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公开(公告)号:US20220143618A1
公开(公告)日:2022-05-12
申请号:US17602826
申请日:2020-04-09
Applicant: RANDOX LABORATORIES LTD
Inventor: Marc Wharry , Martin Reid , Peter Fitzgerald
Abstract: An assay cartridge (31) for use in a molecular diagnostics assay comprising: an assay region (32), possibly containing a plurality of reagent wells (34); a first end comprising a first engagement member (35), such as a lip or protrusion, for engaging with a support housing; and a second end comprising a second engagement member (36) for engaging with a support housing; wherein the second engagement member comprises a clip, the clip being formed by a resilient element extending from the second end of the cartridge and a fastening element extending from said resilient element; wherein the clip comprises a release element extending from the resilient element actuatable to release the clip from a caddy or support housing in use.
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公开(公告)号:US11169093B2
公开(公告)日:2021-11-09
申请号:US16069492
申请日:2017-01-13
Applicant: Randox Laboratories Ltd.
Inventor: Stuart Jackson , Ivan McConnell , Peter Fitzgerald
Abstract: The present invention provides a chemiluminescence detector, which comprises an image capture device sensitive to chemiluminescence located within a container. The container has an array of apertures located in a field of view of the image capture device, and each aperture is defined by a through-bore in a wall of the container. The exterior of the container is engagable with a plurality of sample holders, each sample holder being in alignment with a respective aperture when engaged with the exterior of the container. The passage of light into the container through each aperture is restrictable by a closure device, passage of light into the container through the apertures is thereby controllable.
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公开(公告)号:US10697017B2
公开(公告)日:2020-06-30
申请号:US14367510
申请日:2012-12-21
Applicant: RANDOX LABORATORIES LTD.
Inventor: Sophie Visvikis-Siest , Said El Shamieh , Helena Murray , John Lamont , Peter Fitzgerald
IPC: C12Q1/6883
Abstract: The invention describes epistatic interactions between single nucleotide polymorphisms on genes associated with blood pressure and provides an application for their use in a method to determine an individual's susceptibility to hypertension and hence whether anti-hypertensive treatment will be beneficial for said individual. In addition gene expression levels are also linked to blood pressure and may also be used to determine susceptibility to hypertension.
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公开(公告)号:US10646876B2
公开(公告)日:2020-05-12
申请号:US15534460
申请日:2015-12-14
Applicant: Randox Laboratories Ltd.
Inventor: Stuart Jackson , Ivan McConnell , John Lamont , Peter Fitzgerald , Marc Wharry
Abstract: The present invention is directed to a cap for a biochip storage well. The cap comprises a resilient sealant layer capable, under the application of pressure, of forming a vapour-proof seal with a line contact interface formation extending around the perimeter of a biochip storage well.An assay assembly comprising the cap of the invention and a biochip storage is disclosed. Methods of sealing a biochip storage well using a cap of the invention are also disclosed.
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公开(公告)号:US20170184611A1
公开(公告)日:2017-06-29
申请号:US15457297
申请日:2017-03-13
Applicant: Randox Laboratories Ltd.
Inventor: John Lamont , Ivan Mc Connell , Peter Fitzgerald
IPC: G01N33/68
CPC classification number: G01N33/6893 , C12Q1/6883 , C12Q2600/158 , G01N33/6842 , G01N2333/4737 , G01N2333/5412 , G01N2333/70503 , G01N2333/70525 , G01N2333/70542 , G01N2333/70564 , G01N2333/7151 , G01N2800/2871 , G01N2800/32 , G01N2800/60
Abstract: The present invention provides biomarker-based methods for diagnosing stroke in a patient suspected of having suffered a stroke, and also for discriminating between ischemic stroke and transient ischemic attack. Substrates comprising probes for specific combinations of biomarkers useful in the methods of the invention are also described.
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公开(公告)号:US12246323B2
公开(公告)日:2025-03-11
申请号:US17602826
申请日:2020-04-09
Applicant: RANDOX LABORATORIES LTD
Inventor: Marc Wharry , Martin Reid , Peter Fitzgerald
Abstract: An assay cartridge for use in a molecular diagnostics assay having an assay region; a first end comprising a first engagement member for engaging with a support housing; and a second end comprising a second engagement member for engaging with a support housing. The second engagement member has a clip, the clip being formed by a resilient element extending from the second end of the cartridge and a fastening element extending from said resilient element. The clip has a release element extending from the resilient element actuatable to release the clip from a caddy in use.
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公开(公告)号:US12214102B2
公开(公告)日:2025-02-04
申请号:US17602853
申请日:2020-04-09
Applicant: RANDOX LABORATORIES LTD
Inventor: Catherine McCooke , Peter Fitzgerald
Abstract: There is provided a sterilisation monitoring device for a molecular diagnostics analyser. The device comprises a sensor arranged in use to detect radiation; and an analysis unit connected to the sensor. The analysis unit is arranged in use to issue a signal when the radiation level incident on the sensor is lower than a threshold level.
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公开(公告)号:US20220160921A1
公开(公告)日:2022-05-26
申请号:US17602853
申请日:2020-04-09
Applicant: RANDOX LABORATORIES LTD
Inventor: Catherine McCooke , Peter Fitzgerald
Abstract: There is provided a sterilisation monitoring device for a molecular diagnostics analyser. The device comprises a sensor arranged in use to detect radiation; and an analysis unit connected to the sensor. The analysis unit is arranged in use to issue a signal when the radiation level incident on the sensor is lower than a threshold level.
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