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21.
公开(公告)号:US20230089818A1
公开(公告)日:2023-03-23
申请号:US17968927
申请日:2022-10-19
Applicant: LightLab Imaging, Inc.
Inventor: Joseph M. Schmitt , Joel M. Friedman , Christopher Petroff , Amr Elbasiony
Abstract: A method and apparatus of automatically locating in an image of a blood vessel the lumen boundary at a position in the vessel and from that measuring the diameter of the vessel. From the diameter of the vessel and estimated blood flow rate, a number of clinically significant physiological parameters are then determined and various user displays of interest generated. One use of these images and parameters is to aid the clinician in the placement of a stent. The system, in one embodiment, uses these measurements to allow the clinician to simulate the placement of a stent and to determine the effect of the placement. In addition, from these patient parameters various patient treatments are then performed.
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22.
公开(公告)号:US20230075498A1
公开(公告)日:2023-03-09
申请号:US17979072
申请日:2022-11-02
Applicant: LightLab Imaging, Inc.
Inventor: Joseph M. Schmitt , Joel M. Friedman , Christopher Petroff , Amr Elbasiony
Abstract: A method and apparatus of automatically locating in an image of a blood vessel the lumen boundary at a position in the vessel and from that measuring the diameter of the vessel. From the diameter of the vessel and estimated blood flow rate, a number of clinically significant physiological parameters are then determined and various user displays of interest generated. One use of these images and parameters is to aid the clinician in the placement of a stent. The system, in one embodiment, uses these measurements to allow the clinician to simulate the placement of a stent and to determine the effect of the placement. In addition, from these patient parameters various patient treatments are then performed.
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23.
公开(公告)号:US20190380594A1
公开(公告)日:2019-12-19
申请号:US16549814
申请日:2019-08-23
Applicant: LIGHTLAB IMAGING, INC.
Inventor: Joseph M. Schmitt , Joel M. Friedman , Christopher Petroff , Amr Elbasiony
Abstract: A method and apparatus of automatically locating in an image of a blood vessel the lumen boundary at a position in the vessel and from that measuring the diameter of the vessel. From the diameter of the vessel and estimated blood flow rate, a number of clinically significant physiological parameters are then determined and various user displays of interest generated. One use of these images and parameters is to aid the clinician in the placement of a stent. The system, in one embodiment, uses these measurements to allow the clinician to simulate the placement of a stent and to determine the effect of the placement. In addition, from these patient parameters various patient treatments are then performed.
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公开(公告)号:US09435956B1
公开(公告)日:2016-09-06
申请号:US14587784
申请日:2014-12-31
Applicant: LightLab Imaging, Inc.
Inventor: Chenyang Xu , Joseph M. Schmitt
IPC: G02B6/26 , H04B10/077
CPC classification number: G02B6/264 , A61B5/0066 , A61B5/0075 , A61B5/0084 , G02B6/00 , G02B6/26 , G02B6/262 , G02B6/3604 , G02B6/4206 , G02B6/4214 , G02B6/4215 , G02B6/4287 , H04B10/0775
Abstract: In part, the invention relates to a single clad fiber to multi-clad optical fiber connector for use in applying excitation light to a sample and obtaining reflected light from the sample. The connector can include a dual clad optical fiber portion and a single clad optical fiber portion in optical communication with the dual clad optical fiber portion. In one embodiment, a core of the dual clad optical fiber portion and a core of the single clad optical fiber portion have substantially similar indices of refraction. In one embodiment, excitation light is propagated by the core of the dual clad optical fiber. Further, in one embodiment, light reflected by the sample is propagated by the first cladding layer of the dual clad optical fiber portion.
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25.
公开(公告)号:US12082912B2
公开(公告)日:2024-09-10
申请号:US17508484
申请日:2021-10-22
Applicant: LightLab Imaging, Inc.
Inventor: Joseph M. Schmitt , Joel M. Friedman , Christopher Petroff , Amr Elbasiony
CPC classification number: A61B5/02007 , A61B5/0066 , A61B5/0073 , A61B5/0084
Abstract: A method and apparatus of automatically locating in an image of a blood vessel the lumen boundary at a position in the vessel and from that measuring the diameter of the vessel. From the diameter of the vessel and estimated blood flow rate, a number of clinically significant physiological parameters are then determined and various user displays of interest generated. One use of these images and parameters is to aid the clinician in the placement of a stent. The system, in one embodiment, uses these measurements to allow the clinician to simulate the placement of a stent and to determine the effect of the placement. In addition, from these patient parameters various patient treatments are then performed.
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公开(公告)号:US11793462B2
公开(公告)日:2023-10-24
申请号:US15913300
申请日:2018-03-06
Applicant: LightLab Imaging, Inc.
Inventor: Joseph M. Schmitt , Chenyang Xu
IPC: A61B5/00
CPC classification number: A61B5/6852 , A61B5/0066 , A61B5/7264
Abstract: A method and apparatus for determining properties of a tissue or tissues imaged by optical coherence tomography (OCT). In one embodiment the backscatter and attenuation of the OCT optical beam is measured and based on these measurements and indicium such as color is assigned for each portion of the image corresponding to the specific value of the backscatter and attenuation for that portion. The image is then displayed with the indicia and a user can then determine the tissue characteristics. In an alternative embodiment the tissue characteristics is classified automatically by a program given the combination of backscatter and attenuation values.
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27.
公开(公告)号:US20230165471A1
公开(公告)日:2023-06-01
申请号:US18153134
申请日:2023-01-11
Applicant: LightLab Imaging, Inc.
Inventor: Joseph M. Schmitt , Joel M. Friedman , Christopher Petroff , Amr Elbasiony
CPC classification number: A61B5/02007 , A61B5/0066 , A61B5/0073 , A61B5/0084
Abstract: A method and apparatus of automatically locating in an image of a blood vessel the lumen boundary at a position in the vessel and from that measuring the diameter of the vessel. From the diameter of the vessel and estimated blood flow rate, a number of clinically significant physiological parameters are then determined and various user displays of interest generated. One use of these images and parameters is to aid the clinician in the placement of a stent. The system, in one embodiment, uses these measurements to allow the clinician to simulate the placement of a stent and to determine the effect of the placement. In addition, from these patient parameters various patient treatments are then performed.
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28.
公开(公告)号:US20220087544A1
公开(公告)日:2022-03-24
申请号:US17507338
申请日:2021-10-21
Applicant: LightLab Imaging, Inc.
Inventor: Joseph M. Schmitt , Joel M. Friedman , Christopher Petroff , Amr Elbasiony
Abstract: A method and apparatus of automatically locating in an image of a blood vessel the lumen boundary at a position in the vessel and from that measuring the diameter of the vessel. From the diameter of the vessel and estimated blood flow rate, a number of clinically significant physiological parameters are then determined and various user displays of interest generated. One use of these images and parameters is to aid the clinician in the placement of a stent. The system, in one embodiment, uses these measurements to allow the clinician to simulate the placement of a stent and to determine the effect of the placement. In addition, from these patient parameters various patient treatments are then performed.
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公开(公告)号:US09702687B2
公开(公告)日:2017-07-11
申请号:US14535489
申请日:2014-11-07
Applicant: LightLab Imaging, Inc.
Inventor: Joseph M. Schmitt
CPC classification number: G01B9/02091 , A61B5/0066 , A61B5/0073 , G01B9/02004 , G01B9/02043 , G01B9/02069 , G01B2290/25 , G01B2290/60 , H01S3/1062 , H01S5/141 , H01S5/146 , H01S5/5036
Abstract: In one embodiment of the invention, a semiconductor optical amplifier (SOA) in a laser ring is chosen to provide low polarization-dependent gain (PDG) and a booster semiconductor optical amplifier, outside of the ring, is chosen to provide high polarization-dependent gain. The use of a semiconductor optical amplifier with low polarization-dependent gain nearly eliminates variations in the polarization state of the light at the output of the laser, but does not eliminate the intra-sweep variations in the polarization state at the output of the laser, which can degrade the performance of the SS-OCT system.
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公开(公告)号:US20170188831A1
公开(公告)日:2017-07-06
申请号:US15466246
申请日:2017-03-22
Applicant: LightLab Imaging, Inc.
Inventor: Desmond Adler , Joseph M. Schmitt , Mattias Dahlberg , Par Gustafsson , Ulrik Hubinette , Magnus Samuelsson , Johan Svanerudh
CPC classification number: A61B5/0035 , A61B5/0044 , A61B5/0046 , A61B5/0066 , A61B5/0084 , A61B5/0215 , A61B5/6852 , A61B6/504 , A61B6/5247 , A61B8/0891 , A61B8/12 , A61B8/4416 , A61B8/4433 , A61B8/5261 , A61B8/54 , A61B2560/0437 , A61B2560/045 , A61B2560/0456
Abstract: In part, the invention relates to an image data collection system. The system can include an interferometer having a reference arm that includes a first optical fiber of length of L1 and a sample arm that includes a second optical fiber of length of L2 and a first rotary coupler configured to interface with an optical tomography imaging probe, wherein the rotary coupler is in optical communication with the sample arm. In one embodiment, L2 is greater than about 5 meters. The first optical fiber and the second optical fiber can both be disposed in a common protective sheath. In one embodiment, the system further includes an optical element configured to adjust the optical path length of the reference arm, wherein the optical element is in optical communication with the reference arm and wherein the optical element is transmissive or reflective.
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