Abstract:
Delivering a Direct Proof private key in a signed group of keys to a device installed in a client computer system in the field may be accomplished in a secure manner without requiring significant non-volatile storage in the device. A unique pseudo-random value is generated and stored along with a group number in the device at manufacturing time. The pseudo-random value is used to generate a symmetric key for encrypting a data structure holding a Direct Proof private key and a private key digest associated with the device. The resulting encrypted data structure is stored in a signed group of keys (e.g., a signed group record) on a removable storage medium (such as a CD or DVD), and distributed to the owner of the client computer system. When the device is initialized on the client computer system, the system checks if a localized encrypted data structure is present in the system. If not, the system obtains the associated signed group record of encrypted data structures from the removable storage medium, and verifies the signed group record. The device decrypts the encrypted data structure using a symmetric key regenerated from its stored pseudo-random value to obtain the Direct Proof private key, when the group record is valid. If the private key is valid, it may be used for subsequent authentication processing by the device in the client computer system.
Abstract:
In one embodiment of the present invention, a method includes verifying an initiating logical processor of a system; validating a trusted agent with the initiating logical processor if the initiating logical processor is verified; and launching the trusted agent on a plurality of processors of the system if the trusted agent is validated. After execution of such a trusted agent, a secure kernel may then be launched, in certain embodiments. The system may be a multiprocessor server system having a partially or fully connected topology with arbitrary point-to-point interconnects, for example.
Abstract:
A method and apparatus for initiating secure operations in a microprocessor system is described. In one embodiment, one initiating logical processor initiates the process by halting the execution of the other logical processors, and then loading initialization and secure virtual machine monitor software into memory. The initiating processor then loads the initialization software into secure memory for authentication and execution. The initialization software then authenticates and registers the secure virtual machine monitor software prior to secure system operations.
Abstract:
The invention provides methods of monitoring differential gene expression of pharmacodynamic (PD) markers in a patient treated with a Cyclin Dependent Kinase Inhibitor (CDKI), methods of determining the sensitivity of a cell to a CDKI by measuring PD markers and methods of screening for candidate CKDI.
Abstract:
The present invention provides a compound of formula (I): and pharmaceutically acceptable salts, enantiomers, stereoisomers, rotamers, tautomers, diastereomers, or racemates thereof. Also provided are pharmaceutical compositions containing these compounds and methods of treating a disease or condition mediated by CDK9 using these compounds and compositions.
Abstract:
The invention provides novel compositions comprising Imidazopyridine compounds. Also provided are methods of administering the compositions in an effective amount to enhance the immune response of a subject. Further provided are novel compositions and methods of administering the compositions in combination with (an)other agent(s).
Abstract:
The present invention provides compounds of Formula (I): and pharmaceutically acceptable salts thereof. Also provided is a method of using a compound of Formula I for treating a disease or condition mediated by a CDK inhibitor.
Abstract:
The present invention provides a compound of formula (I): and pharmaceutically acceptable salts, enantiomers, stereoisomers, rotamers, tautomers, diastereomers, or racemates thereof. Also provided is a method of treating a disease or condition mediated by CDK9.
Abstract:
An apparatus for combines for the collection of threshed material discharged from the combine and automatically dumping the collected material when a predetermined weight of material is accumulated. The apparatus includes a threshed material collector attached to the combine for rotation about a horizontal axis that is closer to a forward end of the collector than a rearward end of the collector. The collector includes a plurality of horizontally spaced tines extending in a rearward direction and position to collect material discharged from the combine. A counter weight is attached to the collector for controlling the amount of material collected before the collector rotates under the weight of the collected material to a dumping position where the collected material is removed from the collector.
Abstract:
The invention proyides novel compositions comprising imidazoquinoxaline compounds of formula (I) and analogs thereof. Also provided are methods of administering the compositions in an effective amount to enhance the immune response of a subject. Further provided are novel compositions and methods of administering the compositions in combination with (an) other agent (s).