公开(公告)号：US20160354352A1

公开(公告)日：2016-12-08

申请号：US15237642

申请日：2016-08-16

Applicant: Research Cooperation Foundation of Yeungnam University

Inventor： Byeong Seon JEONG ,  Jung Ae KIM ,  Dong Guk KIM ,  You Ra KANG ,  Tae Gyu NAM

IPC: A61K31/44 ,  A61K31/443 ,  A61K31/5377 ,  A61K31/4545 ,  A61K31/496 ,  A61K31/444 ,  A61K31/4439

CPC classification number: A61K31/5377 ,  A61K31/4412 ,  A61K31/496

Abstract: Provided is a method of treating inflammatory bowel disease comprising administering a pharmaceutical composition comprising a 6-aminopyridin-3-ol compound or a pharmaceutically acceptable salt thereof as an active ingredient to a subject, which inhibits colitis in a model of inflammatory bowel disease, and accordingly, they may be suitable for use as a drug for the prevention or treatment of inflammatory bowel disease.

Abstract translation: 本发明提供一种治疗炎症性肠病的方法，其包括向受试者施用包含6-氨基吡啶-3-醇化合物或其药学上可接受的盐作为活性成分的药物组合物，其抑制炎症性肠病模型中的结肠炎，以及 因此，它们可能适合用作预防或治疗炎症性肠病的药物。

公开(公告)号：US20160282392A1

公开(公告)日：2016-09-29

申请号：US15080587

申请日：2016-03-25

Applicant: RESEARCH COOPERATION FOUNDATION OF YEUNGNAM UNIVERSITY

Inventor： Dong-Choon LEE ,  Thanh Hai NGUYEN ,  Yoon-Cheul JEUNG

IPC: G01R27/26 ,  H02P21/22

CPC classification number: H02P21/36 ,  H02M1/14 ,  H02M7/5387

Abstract: The present invention relates to an inverter vector driving system and a method for estimating capacitance using the same. The present invention provides a method for estimating capacitance in an inverter vector driving system including a capacitor to which a rectified DC voltage of a three-phase power supply is charged, and a PWM inverter configured to transform the DC voltage into a three-phase AC voltage to be applied to a motor of an induction motor, including: operating the motor of the IM in a regeneration mode; generating a d-axis voltage command and a q-axis voltage command for the motor; adjusting a pulse of the PWM inverter by using the d-axis voltage command and the q-axis voltage command; and estimating capacitance of the capacitor by using a DC-link voltage and a DC-link current that are generated at the capacitor due to the inclusion of the AC component.

Abstract translation: 本发明涉及一种逆变器矢量驱动系统以及使用该逆变器矢量驱动系统估计电容的方法。 本发明提供了一种用于估计电容的方法，该逆变器矢量驱动系统包括对三相电源的整流直流电压进行充电的电容器，以及PWM逆变器，被配置为将DC电压变换为三相AC 电压施加到感应电动机的电动机，包括：在再生模式下操作IM的电动机; 生成电动机的d轴电压指令和q轴电压指令; 通过使用d轴电压指令和q轴电压指令调整PWM逆变器的脉冲; 并且通过使用由于包括AC分量在电容器处产生的DC链路电压和DC链路电流来估计电容器的电容。

公开(公告)号：US20160068489A1

公开(公告)日：2016-03-10

申请号：US14784957

申请日：2014-04-21

Applicant: Research Cooperation Foundation of Yeungnam University

Inventor： Byeong Seon JEONG ,  Jung Ae KIM ,  Tae gyu NAM ,  Hyun Ji LEE ,  Dong Guk KIM ,  You Ra KANG ,  Jae Hui BEEN ,  You Jin JIN ,  Sushil Chandra REGMI ,  Jaya GAUTAM

IPC: C07D213/75 ,  C07D405/12

CPC classification number: C07D213/75 ,  C07D405/12 ,  C07D409/12

Abstract: The present invention relates to an amidopyridinol derivative or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition including an amidopyridinol derivative or a pharmaceutically acceptable salt thereof as an active component. An amidopyridinol derivative represented by Chemical Formula 1 or a pharmaceutically acceptable salt thereof has an excellent antiangiogenic effect in a chorioallantoic membrane model, and thus is useful as an agent for preventing or treating diseases associated with angiogenesis, such as macular degeneration or arthritis, and also has an excellent colitis-inhibitory effect in a model of inflammatory bowel diseases, and thus is useful as an agent for preventing or treating inflammatory bowel diseases. Upon inoculation of lung cancer cells in a chorioallantoic membrane model, the amidopyridinol derivative of Chemical Formula 1 or the pharmaceutically acceptable salt thereof inhibits angiogenesis and tumor growth that are caused by tumorigenesis, and also inhibits the activity of cathepsin S that plays an important role in metastasis and invasion of cancer, and thus is useful as an inhibitor of cancer growth and metastasis.

Abstract translation: 本发明涉及一种吡啶并吡啶醇衍生物或其药学上可接受的盐，以及包含作为活性组分的氨基吡啶醇衍生物或其药学上可接受的盐的药物组合物。 由化学式1表示的酰胺基吡啶醇衍生物或其药学上可接受的盐在绒毛尿囊膜模型中具有优异的抗血管生成作用，因此可用作预防或治疗与血管生成相关的疾病如黄斑变性或关节炎的药剂 在炎症性肠病模型中具有优异的结肠炎抑制效果，因此可用作预防或治疗炎症性肠病的药剂。 在绒毛尿囊膜模型中接种肺癌细胞后，化学式1的吡啶并吡啶衍生物或其药学上可接受的盐抑制由肿瘤发生引起的血管发生和肿瘤生长，并且还抑制组织蛋白酶S的活性，其在组织蛋白酶S中起重要作用 转移和侵袭癌症，因此可用作癌症生长和转移的抑制剂。

公开(公告)号：US20250148261A1

公开(公告)日：2025-05-08

申请号：US18622741

申请日：2024-03-29

Applicant: RESEARCH COOPERATION FOUNDATION OF YEUNGNAM UNIVERSITY ,  POSTECH RESEARCH AND BUSINESS DEVELOPMENT FOUNDATION

Inventor： Hyun Chul CHOI ,  Jeong Sik LEE ,  Rock Hyun BAEK ,  Kyeong Rae CHO

IPC: G06N3/042

Abstract: Disclosed are a cell-level analysis method of a memory and a computing device for performing the same. The cell-level analysis method of a memory is a cell-level analysis method of a memory that is executed in a computing device including one or more processors and a memory storing one or more programs executed by the one or more processors, the cell-level analysis method including acquiring information on a location of each cell in the memory, generating graph-structured data for a target cell based on the location of each cell in the memory, and training a graph neural network model to predict one or more of an electrical characteristic of the target cell and a program and verify level (PV level) of the target cell by inputting the graph-structured data into the graph neural network model.

公开(公告)号：US12083093B2

公开(公告)日：2024-09-10

申请号：US17413088

申请日：2019-10-11

Applicant: RESEARCH COOPERATION FOUNDATION OF YEUNGNAM UNIVERSITY

Inventor： Jae-Ryong Kim ,  Eok-Cheon Kim ,  Kyong-Jin Jung ,  You Lim Son

IPC: A61K31/35 ,  A61P9/10 ,  A61P11/00 ,  A61P13/12 ,  A61P19/04 ,  A61P27/02

CPC classification number: A61K31/35 ,  A61P9/10 ,  A61P11/00 ,  A61P13/12 ,  A61P19/04 ,  A61P27/02

Abstract: The present invention relates to a composition for preventing or treating cellular senescence-associated diseases comprising salinomycin as an active ingredient, which acts differently depending on the type of senescent cells, and it was confirmed that salinomycin exhibits a senomorphics effect of restoring the function and morphology of fibroblasts and vascular endothelial cells in which senescence is induced and exhibits a senolytics effect of selectively killing aging-induced retinal pigmented epithelial cells, and exhibits a senomorphics effect of restoring the function and morphology of cells, and thus the salinomycin acts differently depending on the type of cells to effectively prevent or treat senile eye disease, tissue fibrosis disease, atherosclerosis, osteoarthritis, degenerative brain disease, chronic skin damage, obesity and diabetes caused by cellular aging and can be provided as a composition for life extension.

公开(公告)号：US20240095913A1

公开(公告)日：2024-03-21

申请号：US18373677

申请日：2023-09-27

Applicant: RESEARCH COOPERATION FOUNDATION OF YEUNGNAM UNIVERSITY

Inventor： Gyu Sang CHOI ,  Kyeong Min PARK ,  Min Cheol CHANG

IPC: G06T7/00 ,  G06T3/40 ,  G06V10/24 ,  G06V10/42 ,  G06V10/74

CPC classification number: G06T7/0012 ,  G06T3/40 ,  G06V10/242 ,  G06V10/42 ,  G06V10/761 ,  G06T2207/10081 ,  G06T2207/10088 ,  G06T2207/20084 ,  G06T2207/30016

Abstract: An apparatus for image transformation for transforming a first medical image into a second medical image based on an artificial neural network technology includes a preprocessing module that receives the first medical image and second medical image obtained by photographing the same part of a body using different photographing techniques and performs preprocessing on the first and second medical images, and an artificial neural network module that receives the preprocessed first medical image and second medical image, respectively, and transforms the first medical image into a second medical image.

公开(公告)号：US11872509B2

公开(公告)日：2024-01-16

申请号：US16651849

申请日：2018-09-27

Applicant: RESEARCH COOPERATION FOUNDATION OF YEUNGNAM UNIVERSITY

Inventor： Jin Young Jung ,  Byeong Jun Lee

IPC: B01D33/15 ,  B01D33/46 ,  G01N1/14 ,  B01D36/00 ,  B01D33/41

CPC classification number: B01D33/15 ,  B01D33/41 ,  B01D33/461 ,  B01D33/466 ,  B01D36/00 ,  G01N1/14

Abstract: A fine particle separating apparatus includes a first filter having a first mesh, the first filter having a first section and a second section with the first mesh therebetween and rotatably mounted in the first filter part. A first flow path allows sludge to flow into the first filter, a second flow path allows an effluent from the first filter party to flow therein, and a third flow path is provided to discharge the effluent from the second flow path to the outside. At least a portion of the effluent flowing into the second flow path is provided to the first filter part in a fluid loop along a fourth flow path, and a fifth flow path is defined in the first section to allow the effluent from the fourth flow path to pass through the first filter part. A storage tank and a pump are also provided.

公开(公告)号：US20230400352A1

公开(公告)日：2023-12-14

申请号：US18125305

申请日：2023-03-23

Applicant: RESEARCH COOPERATION FOUNDATION OF YEUNGNAM UNIVERSITY

Inventor： Jong Ryul YANG

IPC: G01J1/44

CPC classification number: G01J1/44 ,  G01J2001/4446

Abstract: A receiver according to an embodiment is a terahertz band receiver including an antenna configured to receive a terahertz band signal reflected or transmitted from a measurement target, a detector configured to receive a differential signal including a first input signal VTHz and a second input signal −VTHz with phase difference of 180° to each other from the antenna to detect a voltage, and operate in a concurrent mode, and a buffer amplifier configured to amplify and output a signal detected by the detector.

公开(公告)号：US20230264628A1

公开(公告)日：2023-08-24

申请号：US18109403

申请日：2023-02-14

Applicant: RESEARCH COOPERATION FOUNDATION OF YEUNGNAM UNIVERSITY

Inventor： Gun Zung KIM ,  Soo Jung HUR ,  Jeong Sook EOM ,  Yong Wan PARK

IPC: B60Q1/50 ,  G01S13/931 ,  G01S17/931 ,  G01S15/931

CPC classification number: B60Q1/525 ,  G01S13/931 ,  G01S15/931 ,  G01S17/931 ,  B60Q2400/50

Abstract: An active notice device according to an embodiment includes a signal receiver configured to receive a signal generated by the active sensor of the surrounding vehicle, a signal analyzer configured to analyze characteristics of the signal received by the signal receiver, an information generator configured to generate information recognizable by the surrounding vehicle according to user setting, a signal generator configured to amplify and generate characteristics of the signal analyzed by the signal analyzer using the information generated by the information generator, and a signal transmitter configured to transmit the signal amplified and generated by the signal generator to an active sensor of the surrounding vehicle corresponding thereto.

公开(公告)号：US20230005152A1

公开(公告)日：2023-01-05

申请号：US17723767

申请日：2022-04-19

Applicant: RESEARCH COOPERATION FOUNDATION OF YEUNGNAM UNIVERSITY

Inventor： Gyu Sang CHOI ,  Hyun Kwang SHIN

IPC: G06T7/10 ,  G06N3/04

Abstract: An apparatus for image segmentation according to an embodiment includes an acquirer configured to acquire one or more images in which an object is photographed and a segmentation performer configured to perform segmentation on the one or more images using a segmentation model which is deep learned through a plurality of images, in which the segmentation model is a U-Net-based model including a first type module based on depth-wise separable convolution (DSC) and a second type module based on global context network (GCNet).