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公开(公告)号：US20200164375A1
公开(公告)日：2020-05-28
申请号：US16503849
申请日：2019-07-05
发明人： Takao YASUI , Yoshinobu BABA
摘要： The present disclosure provides a device for separating biomolecules comprising a substrate having a planar surface, nanowires disposed on at least a portion of the planar surface, and a fluid chamber formed to include at least a portion of the nanowires.
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公开(公告)号：US20200153636A1
公开(公告)日：2020-05-14
申请号：US16621389
申请日：2018-06-19
申请人： National University Corporation Nagoya University , AutoNetworks Technologies, Ltd. , Sumitomo Wiring Systems, Ltd. , Sumitomo Electric Industries, Ltd.
发明人： Hiroaki Takada , Ryo Kurachi , Hiroshi Ueda
摘要： A communication device stores a first secret key and a first public key, and the on-vehicle authentication device stores a second secret key, a second public key and a signature verification key. The on-vehicle authentication device acquires the first public key, verifies the authenticity of the electronic signature using a signature verification key, encrypts the second public key using the authentic first public key and transmits the encrypted second public key. The communication device receives the encrypted second public key, decrypts the encrypted second public key using the first secret key, encrypts the first public key using the decrypted second public key. The on-vehicle authentication device receives the encrypted first public key, decrypts the encrypted first public key using the second secret key, and authenticates that the communication device is an authentic device when the decrypted first public key has been determined to be authentic.
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公开(公告)号：US10541107B2
公开(公告)日：2020-01-21
申请号：US15505462
申请日：2015-08-21
摘要： A three-dimensional image reconstruction method associated with the present invention includes the steps of: obtaining a first transmission electron microscope image of a sample containing the membrane proteins present within a lipid membrane, the image having been taken by illuminating an electron beam on the sample from a direction tilted relative to a line normal to the membrane surface of the lipid membrane; obtaining a second transmission electron microscope image of the sample taken by illuminating the electron beam on the sample perpendicularly to the membrane surface of the lipid membrane; identifying orientations of the membrane proteins of the first transmission electron microscope image on a basis of the second transmission electron microscope image; and analyzing a three-dimensional structure of the membrane proteins from the first transmission electron microscope image on a basis of information about the identified orientations of the membrane proteins.
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公开(公告)号：US10481169B2
公开(公告)日：2019-11-19
申请号：US15906032
申请日：2018-02-27
发明人： Koji Uchida , Takahiro Shibata , Kenji Ishikawa , Oi Lun Helena Li , Tadashi Matsushita , Ryosuke Kikuchi , Junzo Ukai
摘要： Provided is a novel method and the like for diagnosing a lifestyle disease. The method for diagnosing a lifestyle disease provided by the present invention includes: collecting a biological sample from a subject; measuring the concentration of a fatty acid amide contained in the biological sample; determining whether the subject suffers from a lifestyle disease or a lifestyle disease has progressed when the measured value of the concentration of the fatty acid amide in the sample obtained from the subject is lower than a measurement result obtained from a healthy subject.
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公开(公告)号：US20190334072A1
公开(公告)日：2019-10-31
申请号：US16472985
申请日：2017-12-22
摘要： A thermoelectric conversion material according to an embodiment is expressed by the following formula (1): (M11-xM2x)4Si(Te1-yM3y)4 (1) wherein M1 represents Ta or Nb, M2 is at least one element selected from a group consisting of elements of groups 4 to 12 in the periodic table, M3 is at least one element selected from a group consisting of As, Sb, Bi, Sn and Pb, 0≤x
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公开(公告)号：US10386314B2
公开(公告)日：2019-08-20
申请号：US15772501
申请日：2016-11-02
发明人： Toru Ujihara , Fumiaki Ichihashi , Takahiko Kawaguchi , Takahiro Ito , Makoto Kuwahara , Peter Baltzer , Yukio Takeuchi
IPC分类号： G01N23/227 , H01J49/48 , G01N23/2273 , H01J49/46
摘要： Electrons excited by irradiation of a visible light to a sample is at an energy level lower than a vacuum level, thus photoelectrons are not emitted from the sample and energy of excited electrons cannot be measured. The visible light is irradiated to the sample through a mesh electrode. A surface film for reducing the vacuum level is formed on a surface of the sample. With the surface film being formed, photoelectrons are obtained by the visible light, and these photoelectrons are accelerated by the mesh electrode toward a photoelectron spectrometer. Ultraviolet light may be irradiated to the sample and metal having same potential therewith. In this case, the mesh electrode is set at a retracted position to prohibit interaction of the mesh electrode and the ultraviolet light. A difference between the valence band and the Fermi level of the sample can be measured.
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公开(公告)号：US20190245234A1
公开(公告)日：2019-08-08
申请号：US16256186
申请日：2019-01-24
发明人： Naoki NAKAMURA , Atsushi NORO , Takato KAJITA , Haruka TANAKA , Yushu MATSUSHITA
IPC分类号： H01M8/1048 , H01M8/1069
CPC分类号： H01M8/1048 , H01M8/1069 , H01M2008/1095 , H01M2300/0082
摘要： [OBJECT] To provide a proton-conductive membrane which exhibits high proton conductivity even in an anhydrous environment.[SOLVING MEANS] Provided is a proton-conductive membrane including a crosslinked polymer and a plasticizer, wherein the crosslinked polymer includes a proton acceptor group in an amount equal to not less than 10 mol % of repeating units constituting the crosslinked polymer, the plasticizer includes a proton donor compound having a pKa value of not more than 2.5, and the plasticizer is a viscoelastic solid in a temperature range of 50° C. to 120° C.
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公开(公告)号：US20190240262A1
公开(公告)日：2019-08-08
申请号：US16322781
申请日：2017-08-03
申请人： National University Corporation Nagoya University , Life Science Institute, Inc. , TOHOKU UNIVERSITY
发明人： Yoshiaki SATO , Toshihiko SUZUKI , Shinobu SHIMIZU , Masaaki MIZUNO , Masahiro HAYAKAWA , Mari DEZAWA
IPC分类号： A61K35/545 , A61P11/00
CPC分类号： A61K35/545 , A61P11/00
摘要： The purpose of the present invention is to provide a novel medical use of pluripotent stem cells (Muse cells) in the regenerative medicine area. Provided are a cell preparation and a medicinal composition for ameliorating and treating chronic lung disease in newborns, said cell preparation and medicinal composition comprising SSEA-3-positive pluripotent stem cells isolated from a mesenchymal tissue in a living body or cultured mesenchymal cells. The cell preparation according to the present invention is based on a mechanism whereby the aforesaid disease is ameliorated and treated by administering Muse cells to a subject suffering from the disease and engrafting the cells in lung tissues.
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公开(公告)号：US10350310B2
公开(公告)日：2019-07-16
申请号：US16101544
申请日：2018-08-13
申请人： NATIONAL UNIVERSITY CORPORATION MIE UNIVERSITY , NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY
IPC分类号： A61B5/00 , A61B8/00 , A61B10/00 , A61K49/00 , C08B37/16 , C09B23/01 , C09B23/08 , A61B5/0205 , A61B5/026 , A61B5/20 , A61M5/00 , C09B67/00 , A61B5/0275
摘要： The present invention aims at providing a novel indocyanine compound solving problems of conventionally used indocyanine green, such as solubility in water or physiological saline, a synthesis method and a purification method thereof, and a diagnostic composition including the novel indocyanine compound. Further, provided are a method for evaluating biokinetics of the novel indocyanine compound and a device for measuring biokinetics, and a method and a device for visualizing circulation of fluid such as blood in a living body, which utilize the diagnostic composition. Also, found are a novel indocyanine compound in which a hydrophobic moiety in a near-infrared fluorescent indocyanine molecule is included in a cavity of a cyclic sugar chain cyclodextrin to cover the hydrophobic moiety in the indocyanine molecule with the glucose, and a synthesis method and a purification method thereof. Furthermore, found are a method for fluorescence-imaging an organ other than liver by intravenous administration, a method for evaluating biokinetics of the novel indocyanine compound, a device for measuring biokinetics, and a method and a device for visualizing circulation of fluid such as blood in a living body, utilizing the diagnostic composition including the novel indocyanine compound.
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公开(公告)号：US20190168425A1
公开(公告)日：2019-06-06
申请号：US16310008
申请日：2017-05-11
申请人： HONDA MOTOR CO., LTD. , SUBARU CORPORATION , SUZUKI MOTOR CORPORATION , TOYOTA JIDOSHA KABUSHIKI KAISHA , Toray Industries, Inc. , KYOWA INDUSTRIAL CO., LTD. , NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY , AISIN SEIKI KABUSHIKI KAISHA , Mitsubishi Jidosha Kogyo Kabushiki Kaisha , TOHO TENAX CO., LTD.
发明人： Satoshi Hirawaki , Masashi Horikawa , Shusuke Sanai , Kanji Takaoka , Kazuaki Amaoka , Munehito Kawakami , Kazuki Baba
摘要： A molding method and a molding system for improving a molding speed of a resin molded member. In the method, firstly a thermoplastic resin composite material is filled in a metal mold (i.e., at time T0), and subsequently a mold-clamping process gets started. As the mold-clamping process progresses, a first decompression circuit starts to decompress an inside of a cavity when the cavity is closed by a sealing member provided on the metal mold. Then, as the mold-clamping process further progresses, the thermoplastic resin composite material thus filled in the metal mold contacts an upper mold of the metal mold (i.e., at time T2). After that, a second decompression circuit starts to decompress the inside of the cavity, thereby to complete the mold-clamping process (i.e., at time T3).
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