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21.发明授权Diagnostic aid for the scintigraphic visualization of malignant tumors comprising the substance obtained from enzymatic processing of murein using hen's eggwhite lysozyme 失效包括使用母鸡蛋白溶菌酶酶解加工murein的物质的恶性肿瘤的闪烁照相可视化的诊断辅助
公开(公告)号：US4885151A
公开(公告)日：1989-12-05
申请号：US66185
申请日：1987-06-25
Applicant: Erich Oberhausen , Ludwig Kuhlmann , Gerhard Seibert , Axel Steinstrasser , Hans-Joachim Schroth , Karl-Heinz Bremer
Inventor： Erich Oberhausen , Ludwig Kuhlmann , Gerhard Seibert , Axel Steinstrasser , Hans-Joachim Schroth , Karl-Heinz Bremer
CPC classification number: A61K51/088 , A61K2123/00
Abstract: A diagnostic aid for the scintigraphic visualization of malignant tumors which contains a radionuclide which is bonded by means of a complex-forming agent to the substance obtained by the enzymatic processing of murein with enzyme consisting essentially of hen's eggwhite lysozyme.
Abstract translation: 用于含有通过络合物形成剂与通过酶蛋白酶蛋白酶处理的酶与酶基本上由鸡蛋白溶菌酶组成的酶结合的放射性核素的恶性肿瘤的闪烁照相可视化的诊断辅助。
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公开(公告)号：US4861775A
公开(公告)日：1989-08-29
申请号：US89153
申请日：1987-08-25
Applicant: Axel Zeeck , Sabine Breiding-Mack , Susanne Grabley , Hartmut Voelskow , Gerhard Seibert
Inventor： Axel Zeeck , Sabine Breiding-Mack , Susanne Grabley , Hartmut Voelskow , Gerhard Seibert
IPC: A61K31/535 , A61K31/538 , A61P31/04 , A61P31/10 , A61P31/12 , A61P33/02 , A61P33/10 , A61P43/00 , C07D265/38 , C12N1/20 , C12P17/14 , C12P17/18 , C12R1/465
CPC classification number: C12R1/465 , C07D265/38 , C12P17/14
Abstract: Streptomyces spec. DSM 3813 produces novel compounds with a basic phenoxazinone structure, which have an antifungal and antiviral action and can be used as lipoxygenase inhibitors.
Abstract translation: 链霉菌规格 DSM 3813生产具有碱性吩嗪酮结构的新型化合物，其具有抗真菌和抗病毒作用，可用作脂氧合酶抑制剂。
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公开(公告)号：US4647556A
公开(公告)日：1987-03-03
申请号：US471649
申请日：1983-03-03
Applicant: Rudolf Lattrell , Reiner Kirrstetter , Wilfried Schwab , Walter Durckheimer , Gerhard Seibert
Inventor： Rudolf Lattrell , Reiner Kirrstetter , Wilfried Schwab , Walter Durckheimer , Gerhard Seibert
IPC: C07D501/36 , A61K31/545 , A61K31/546 , A61P31/04 , C07D277/20 , C07D501/34 , C07D501/46 , C07D501/38
CPC classification number: C07D277/587
Abstract: The invention relates to cephem derivatives of the general formula I ##STR1## and their physiologically acceptable acid addition salts, to pharmaceutical formulations active against bacterial infections, to processes for preparing the compounds and formulations, and to the use of the compounds for combating bacterial infections.
Abstract translation: 本发明涉及通式Ⅰ的头孢烯衍生物及其生理上可接受的酸加成盐，对抗细菌感染的药物制剂，制备化合物和制剂的方法，以及该化合物用于抗菌感染的用途 。
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公开(公告)号：US4165052A
公开(公告)日：1979-08-21
申请号：US892962
申请日：1978-04-03
Applicant: Gerhard Seibert
Inventor： Gerhard Seibert
Abstract: A device for winding or unwinding of a cord-shaped material on and off a spool, respectively, with a spool support unit comprising two adjustable sleeves and a drive mechanism for rotating the spool, and with the spool support unit being suspended on a carrier. The support unit is mounted on the carrier rotatable out of its operating position by at least 90.degree. around a vertical axis.
Abstract translation: 用于将线状材料分别缠绕在卷轴上或从卷轴上脱开的装置，其中卷轴支撑单元包括两个可调整的套筒和用于旋转卷轴的驱动机构，并且卷轴支撑单元悬挂在托架上。 支撑单元安装在托架上，围绕垂直轴可旋转超出其工作位置至少90度。
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公开(公告)号：US4132369A
公开(公告)日：1979-01-02
申请号：US892189
申请日：1978-03-31
Applicant: Gerhard Seibert
Inventor： Gerhard Seibert
CPC classification number: B65H51/20
Abstract: A compensating storage for cable or the like comprising a group of rollers fixed on a frame and a group of compensating rollers moveable on horizontal rails, the compensating rollers being loaded by a storage tensioning device, whereby the cable is wound around both groups of rollers as a pulley rope. Support rollers for the upper cable strands are arranged between both groups of rollers, the support rollers being moveable on horizontal rails. The support rollers on the one hand lie in the path of movement of the inwardly moving compensating rollers and are able to be pushed together by the latter, and on the other hand are able to be drawn apart from one another by towing members which are connected to the compensating rollers.
Abstract translation: 用于电缆等的补偿存储器包括固定在框架上的一组辊和可在水平轨道上移动的一组补偿辊，补偿辊由存放张紧装置加载，由此将电缆缠绕在两组辊上，如 滑轮绳。 用于上部电缆股的支撑辊布置在两组辊之间，支撑辊可在水平导轨上移动。 支撑辊一方面位于向内移动的补偿辊的移动路径中，并且能够被后者推动在一起，另一方面能够通过连接的牵引构件彼此分离 补偿辊。
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Patent Agency Ranking
公开(公告)号：US08476222B2
公开(公告)日：2013-07-02
申请号：US12417307
申请日：2009-04-02
Applicant: Gerhard Seibert , László Vértesy , Joachim Wink , Irvin Winkler , Mark Broenstrup , Holger Hoffmann , Hans Guehring , Luigi Toti , Roderich Süssmuth , George M. Sheldrick , Kathrin Meindl
Inventor： Gerhard Seibert , László Vértesy , Joachim Wink , Irvin Winkler , Mark Broenstrup , Holger Hoffmann , Hans Guehring , Luigi Toti , Roderich Süssmuth , George M. Sheldrick , Kathrin Meindl
Abstract: The disclosure relates to a compound of the formula (I) wherein R1 is H, C(O)—(C1-C6)alkyl or C(O)—O—(C1-C6)alkyl; R2 is OH, NH2, NH—(C1-C6)alkyl, NH—(C1-C4)alkylene-phenyl or NH—(C1-C4)alkylene-pyridyl; R3 and R4 are independently of each other H or OH, or R3 and R4 together are ═O; and m and n are independently of one another 0, 1 or 2; in any stereochemical form, or a mixture of any stereochemical forms in any ratio, or a physiologically acceptable salt thereof, obtainable from Actinomadura namibiensis (DSM 6313), and its use for the treatment of bacterial infections, viral infections and/or pain, and pharmaceutical composition comprising it.
Abstract translation: 本发明涉及式（I）化合物，其中R 1是H，C（O） - （C 1 -C 6）烷基或C（O）-O-（C 1 -C 6）烷基; R2是OH，NH2，NH-（C1-C6）烷基，NH-（C1-C4）亚烷基 - 苯基或NH-（C1-C4）亚烷基 - 吡啶基; R3和R4彼此独立地为H或OH，或R3和R4一起为= O; m和n彼此独立地为0,1或2; 任何立体化学形式，或任何比例的任何立体化学形式的混合物，或其生理学上可接受的盐，可从放线杆菌素（DSM 6313）获得，以及其用于治疗细菌感染，病毒感染和/或疼痛的用途，以及 包含它的药物组合物。
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公开(公告)号：US20090298904A1
公开(公告)日：2009-12-03
申请号：US12417307
申请日：2009-04-02
Applicant: Gerhard Seibert , László Vértesy , Joachim Wink , Irvin Winkler , Mark Broenstrup , Holger Hoffmann , Hans Guehring , Luigi Toti , Roderich Süssmuth , George M. Sheldrick , Kathrin Meindl
Inventor： Gerhard Seibert , László Vértesy , Joachim Wink , Irvin Winkler , Mark Broenstrup , Holger Hoffmann , Hans Guehring , Luigi Toti , Roderich Süssmuth , George M. Sheldrick , Kathrin Meindl
IPC: A61K31/40 , C07D513/18 , C12P17/18
Abstract: The disclosure relates to a compound of the formula (I) wherein m and n are independently of one another 0, 1 or 2, obtainable from Actinomadura namibiensis (DSM 6313), its use for the treatment of bacterial infections, viral infections and/or pain, and pharmaceutical composition comprising it.
Abstract translation: 本公开涉及式（I）的化合物，其中m和n彼此独立地为0,1或2，可从放线菌素（DSM 6313）获得，其用于治疗细菌感染，病毒感染和/或 疼痛和包含它的药物组合物。
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公开(公告)号：US5799477A
公开(公告)日：1998-09-01
申请号：US750685
申请日：1997-03-17
Applicant: Gerhard Seibert
Inventor： Gerhard Seibert
CPC classification number: H01B13/0257
Abstract: A device for making a wire strand with changing twist direction (SZ-stranding) from individual wires, includes a fixed guide (1) provided with bores for receiving the individual wires and a plurality of spaced apart storing disks (4) capable of being driven in changing directions and also having bores for receiving the individual wires to be stranded, and a laying disk (6) capable of being driven via drive disks (7) and transmission members (9), with a drive (8) common to at least a portion of the drive disks (7) being provided, wherein between the drive (8) and the drive disks (7) there is disposed a torsionally elastic shaft (15) having an arbitrary cross-section.
Abstract translation: PCT No.PCT / AT95 / 00137 Sec。 371日期1997年3月17日 102（e）1997年3月17日PCT申请1995年6月28日PCT公布。 公开号WO96 / 00970 日期1996年1月11日一种用于从单根线制造具有变化的扭转方向（SZ-绞合）的线束的装置包括：固定导向器（1），其设置有用于接收各个线的孔和多个间隔开的存储盘（4 ），能够沿变化的方向被驱动，并且还具有用于接收待绞合的各个线的孔，以及能够通过驱动盘（7）和传动构件（9）驱动的铺设盘（6），其具有驱动器（8） ），其中设置有驱动盘（7）的至少一部分，其中在驱动器（8）和驱动盘（7）之间设置有具有任意横截面的扭转弹性轴（15）。
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29.发明授权Microorganism for breaking down moenomycins, a process for the breakdown, and the use of the breakdown products 失效用于分解莫宁霉素的微生物，破裂的过程以及分解产物的使用
公开(公告)号：US5315038A
公开(公告)日：1994-05-24
申请号：US048511
申请日：1993-04-20
Applicant: Werner Aretz , Dirk Bottger , Gerhard Seibert , Alois Tumulka , Peter Welzel , Kurt Hobert
Inventor： Werner Aretz , Dirk Bottger , Gerhard Seibert , Alois Tumulka , Peter Welzel , Kurt Hobert
IPC: C07C59/125 , C07C59/60 , C07F9/09 , C07F9/655 , C07H13/12 , C12N9/16 , C12P7/42 , C12P19/26 , C12P19/44 , C07C59/01
CPC classification number: C07H13/12 , C07C59/125 , C07C59/60 , C07F9/091 , C07F9/6552 , C12N9/16 , C12P19/26 , C12P19/44 , C12P7/42 , C12R1/07
Abstract: A new microorganism for breaking down moenomycins, a process for the breakdown, and the use of the breakdown products are disclosed. A new Bacillus species and the appropriate enzymes obtained therefrom can be used to break down phosphoglycolipid antibiotics. The breakdown products of moenomycins display antibiotic activity or can be used as building blocks for the synthetic preparation of transglycosylase inhibitors.
Abstract translation: 公开了一种用于分解霉菌素的新微生物，破坏的过程以及分解产物的使用。 可以使用新的芽孢杆菌种类和由其获得的合适的酶来分解磷脂糖抗生素。 莫内霉素的分解产物显示抗生素活性，或可用作合成制备转糖基酶抑制剂的结构单元。
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公开(公告)号：US5260206A
公开(公告)日：1993-11-09
申请号：US938599
申请日：1992-09-03
Applicant: Werner Aretz , Dirk Bottger , Gerhard Seibert , Alois Tumulka , Peter Welzel , Kurt Hobert
Inventor： Werner Aretz , Dirk Bottger , Gerhard Seibert , Alois Tumulka , Peter Welzel , Kurt Hobert
IPC: C07C59/125 , C07C59/60 , C07F9/09 , C07F9/655 , C07H13/12 , C12N9/16 , C12P7/42 , C12P19/26 , C12P19/44 , C12N1/20 , C12N9/14
CPC classification number: C07H13/12 , C07C59/125 , C07C59/60 , C07F9/091 , C07F9/6552 , C12N9/16 , C12P19/26 , C12P19/44 , C12P7/42 , C12R1/07 , Y10S435/832
Abstract: A new Bacillus species and the appropriate enzymes obtained therefrom can be used to break down phosphoglycolipid antibiotics. The breakdown products of moenomycins display antibiotic activity or can be used as building blocks for the synthetic preparation of transglycosylas inhibitors.
Abstract translation: 可以使用新的芽孢杆菌种类和由其获得的合适的酶来分解磷脂糖抗生素。 莫内霉素的分解产物显示抗生素活性，或可用作合成制备转糖基酶抑制剂的结构单元。
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