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21.发明授权公开(公告)号：US11860188B2
公开(公告)日：2024-01-02
申请号：US17703791
申请日：2022-03-24
发明人： Wooyoung Shim , Gwangmook Kim
CPC分类号： G01Q60/40 , G01Q10/065 , G01Q70/06
摘要： Provided is a scanning probe microscope, and in particular, a scanning probe microscope capable of scanning a large area using a probe including a plurality of conductive tips and capable of simply generating a surface image of a sample with high resolution by recognizing only two binary states of contact/non-contact between the conductive tips and a surface of the sample.
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公开(公告)号：US20230416910A1
公开(公告)日：2023-12-28
申请号：US18368084
申请日：2023-09-14
发明人： Jong Hyun AHN , Xiang CHEN , Yong Ju PARK , Min Pyo KANG
IPC分类号： C23C16/40 , C23C16/458 , G01N33/50
CPC分类号： C23C16/403 , C23C16/4586 , G01N33/5091 , C23C16/345
摘要： The present invention discloses a transient sensor using molybdenum disulfide and a method of manufacturing the same. According to one embodiment of the present invention, the transient sensor using molybdenum disulfide includes a water-soluble substrate; a water-soluble insulating layer deposited on the water-soluble substrate; an electrode layer formed of any one of molybdenum (Mo) and magnesium (Mg) and formed on the water-soluble insulating layer; and a channel layer formed of molybdenum disulfide and formed on the water-soluble insulating layer to be connected to the electrode layer. In addition, when the transient sensor is inserted into living matter, the transient sensor can be dissolved within a critical time in the living matter.
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23.发明公开公开(公告)号：US20230415268A1
公开(公告)日：2023-12-28
申请号：US17478763
申请日：2021-09-17
发明人： Shinill KANG , Run Jia HAN
IPC分类号： B23K26/352 , B23K26/70 , B23K26/60 , B21J1/06
CPC分类号： B23K26/352 , B21J1/06 , B23K26/60 , B23K26/70
摘要： A device and method for imprinting a metal member using an external electric field and an IR band laser transmissive mold method are provided. The device includes a laser-beam generating device spaced apart from a surface of the metal member that is to be imprinted, and generating a laser beam of an IR band to radiate the laser beam onto the metal member surface, an electric-field forming device forming an electric field between both side surfaces of the metal member perpendicular to a direction in which the laser beam is incident, and a mold made of a material through which the laser beam may be transmitted, having on a surface thereof a fine pattern to form the fine pattern on the metal member surface, and performing an imprinting operation while coming into contact with the metal member surface that is softened by irradiation of the laser beam.
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公开(公告)号：US11849959B2
公开(公告)日：2023-12-26
申请号：US16965207
申请日：2019-02-12
发明人： Yong Yeob Cha , Hong Ho Kim , Seong Yi
CPC分类号： A61B17/1757 , A61B17/1735 , A61B17/7082 , A61B34/30 , A61B2017/00367 , A61B2017/00477
摘要： A medical screw surgical device includes: a surgical device main body shaped like a bar and internally formed with an insertion passage; an extension member provided in a lower portion of the surgical device main body and internally formed with a guide hole; a guide member movably provided in the guide hole of the extension member; and a firing member provided in the insertion passage of the surgical device main body and controlling the guide member to move up and down. A surgical robot having a robot arm with the medical screw surgical device includes: a support arm provided in the robot arm; a surgical device holding member provided in the support arm; and the medical screw surgical device provided in the surgical device holding member.
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公开(公告)号：US11826324B2
公开(公告)日：2023-11-28
申请号：US17126478
申请日：2020-12-18
发明人： Jungsik Song , Beom Seok Kim , Sang Jun Ha , Ji Min Son
IPC分类号： A61K31/155 , A61K31/436 , A61K31/40
CPC分类号： A61K31/155 , A61K31/40 , A61K31/436
摘要： Provided are a pharmaceutical composition for preventing or treating inflammatory disease, autoimmune disease, graft rejection responses, or combinations thereof, the pharmaceutical composition including a compound represented by Formula 1, or a stereoisomer, derivative, solvate, or pharmaceutically acceptable salt thereof, and a method using the pharmaceutical composition. The pharmaceutical composition and the method can be used to effectively prevent or treat inflammatory disease, autoimmune disease, graft rejection responses, or combinations thereof.
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公开(公告)号：US11806364B2
公开(公告)日：2023-11-07
申请号：US16652349
申请日：2018-09-28
申请人： Industry-Academic Cooperation Foundation, Yonsei University , Research & Business Foundation Sungkyunkwan University
发明人： Sung Jae Shin , Woo Sik Kim , Hong Min Kim , Kee Woong Kwon , Joo Heon Yoon , Won Jung Koh
CPC分类号： A61K35/15 , C12N5/0669 , C12N2501/22 , C12N2501/2306 , C12N2501/24
摘要： The present invention relates to a method for inducing differentiation of bone marrow cells into myeloid-derived suppressor cells (MDSCs) by treating the bone marrow cells with a toll-like receptor agonist (TLR agonist) or type I interferon, or for inducing dendritic cells from the MDSCs.
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27.发明公开公开(公告)号：US20230352120A1
公开(公告)日：2023-11-02
申请号：US18309208
申请日：2023-04-28
发明人： Hyongbum Henry KIM , Nahye KIM
摘要： According to a system for predicting the efficiency and an outcome of a base editor by using deep learning, it is possible to select a base editor from among 63 base editors with various protospacer adjacent motif (PAM) compatibilities and sgRNA for efficient base editing, without extensive experiments. Therefore, the system may be usefully used in all fields where gene editing is applied, such as disease treatment by gene editing.
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公开(公告)号：US20230349927A1
公开(公告)日：2023-11-02
申请号：US18307891
申请日：2023-04-27
发明人： Seong Chan JUN , Chae Kwang IM , Ji Sang HA , Se Won PARK , Jae Kyeong LEE , Tae Wook LEE
IPC分类号： G01N33/68 , G01N33/543
CPC分类号： G01N33/6896 , G01N33/5438 , G01N2800/2821 , G01N2333/4709
摘要： Disclosed herein are an RF biosensing system, a method of manufacturing an RF biosensor used in the same, and a method of controlling the same. The RF biosensing system allows dementia screening without any painful or uncomfortable procedure through rapid detection of biomarkers for Alzheimer's disease present in a patient's bodily fluids. In addition, the RF biosensing system is very helpful for preventing Alzheimer's disease due to the ability to detect triggers for dementia long before onset of symptoms and easily monitor the progression of Alzheimer's disease using simple and inexpensive equipment.
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公开(公告)号：US11802350B2
公开(公告)日：2023-10-31
申请号：US17146224
申请日：2021-01-11
发明人： Woo Young Shim , Sang jin Choi , Hyesoo Kim
IPC分类号： C30B29/42 , C30B11/00 , C30B29/68 , H01L21/02 , H01L29/06 , H01L29/20 , C01G28/00 , C30B33/08
CPC分类号： C30B29/42 , C01G28/002 , C30B11/003 , C30B29/68 , C30B33/08 , H01L21/02546 , H01L21/02623 , H01L29/0665 , H01L29/20 , C01P2002/02 , C01P2002/72 , C01P2002/76
摘要： The present invention relates to: layered gallium arsenide (GaAs), which is more particularly layered GaAs, which, unlike the conventional bulk GaAs, has a two-dimensional crystal structure, has the ability to be easily exfoliated into nanosheets, and exhibits excellent electrical properties by having a structure that enables easy charge transport in the in-plane direction; a method of preparing the same; and a GaAs nanosheet exfoliated from the same.
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公开(公告)号：US20230320653A1
公开(公告)日：2023-10-12
申请号：US17927760
申请日：2021-05-26
发明人： Jae Yong SHIN , Joo Young OH , Sang Eun LEE
CPC分类号： A61B5/445 , A61B5/7267 , A61B5/7275 , A61B5/486 , G16H50/20
摘要： The present invention provides an apparatus for managing atopic dermatitis based on a learning model and a method therefor. The method for managing atopic dermatitis according to the present invention includes the steps of: collecting, basic data including a patient's daily life factor, biometric factor, mental health factor, skin status factor, weather-related environmental factor, and an atopic dermatitis severity index based on the medical record; learning a weight for each detailed variable by applying, to a learning model, the relationship between the atopic dermatitis severity index and respective detailed variables for a plurality of factors; determining a reference value of the weight for selecting, as valid variables, N detailed variables for each factor; reconstructing the learning model by selecting, for each factor, N valid variables; and predicting the atopic dermatitis severity index by applying, to the reconstructed learning model, the currently corrected basic data of the patient to be analyzed.
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