MODIFIED PROTEIN AND METHOD FOR USING SAME
    18.
    发明申请

    公开(公告)号:US20200299744A1

    公开(公告)日:2020-09-24

    申请号:US16765658

    申请日:2019-01-30

    申请人: HITACHI, LTD.

    摘要: The present invention pertains to a means and method for, from a mixture (cell culture) of cells, a medium component, and a useful substance, recovering the first two using a single process. Specifically, the present invention pertains to a polypeptide modified with a stimulus-responsive polymer, characterized in that the stimulus-responsive polymer responds to a stimulus to induce a change in the physical properties of the modified polypeptide overall, and the change is reversible or pseudo-reversible.

    COMPOSITION CONTAINING A POLYMER AND AN ADDITIVE

    公开(公告)号:US20200299484A1

    公开(公告)日:2020-09-24

    申请号:US16763689

    申请日:2018-11-14

    摘要: The invention describes a composition containing a) a functionalized polymer (10) that comprises at least one polymer segment (13) and at least two polymer aggregating segments (11,12) capable of forming non-covalent bonds based on a supramolecular interaction, b) an aggregating additive (20) that comprises at least one additive aggregating segment (21) capable of forming non-covalent bonds based on the same supramolecular interaction as the polymer aggregating segments (11,12), wherein the polymer aggregating segments (11,12) and the additive aggregating segment (21) are ditopic, wherein the polymer aggregating segments (11,12) and the additive aggregating segment (21) are designed such that they can form aggregates (31) that contain polymer aggregating segments (11,12) and additive aggregating segments (21), and wherein the aggregating additive (20) has a molecular weight of from 50 g/mol to 2000 g/mol. The invention also describes a method for the preparation of the composition according to the invention, the use of an aggregating additive (20) with a functionalized polymer (10), and the use of the composition according to the invention.