Poly(CPP-SA) Anhydride As A Reactive Barrier Matrix Against Percutaneous Absorption Of Toxic Chemicals
    15.
    发明申请
    Poly(CPP-SA) Anhydride As A Reactive Barrier Matrix Against Percutaneous Absorption Of Toxic Chemicals 有权
    聚(CPP-SA)酐作为反应性阻隔基体经皮吸收有毒化学物质

    公开(公告)号:US20120237471A1

    公开(公告)日:2012-09-20

    申请号:US13422874

    申请日:2012-03-16

    摘要: The present invention relates to a protective agent suitable to protect the human skin against toxic materials, particularly against chemicals with nucleophilic sites. The active moiety is a polyanhydride derivative. The active transdermal retardant offers a barrier property and chemically and/or physically reacts with harmful chemicals to decrease percutaneous absorption. In the preferred embodiments, polyanhydride in its low molecular weight form reduced flux of nicotine and nitrofurazone significantly. Additionally, polyanhydride in its high molecular weight form prevented nicotine absorption and decreased nitrofurazone permeation dramatically. Moreover, the polyanhydride in its high molecular weight form reduced nitroglycerin flux to a lesser extent.

    摘要翻译: 本发明涉及适于保护人体皮肤免受有毒物质特别是具有亲核部位的化学物质的保护剂。 活性部分是聚酐衍生物。 活性透皮阻滞剂提供阻隔性质,并与有害化学物质化学和/或物理反应以降低经皮吸收。 在优选的实施方案中,其低分子量形式的聚酐显着降低了尼古丁和呋喃西林的通量。 另外,其高分子量形式的聚酐阻止了尼古丁吸收,并显着降低了呋喃西林的渗透。 此外,其高分子量形式的聚酐在较小程度上减少了硝酸甘油的通量。

    Adsorbent And Process For Producing The Same
    16.
    发明申请
    Adsorbent And Process For Producing The Same 审中-公开
    吸附剂及其制备方法

    公开(公告)号:US20070270307A1

    公开(公告)日:2007-11-22

    申请号:US11597910

    申请日:2005-05-27

    摘要: An object of the invention is to provide an adsorbent having high adsorbability per unit volume and a high adsorption rate as an adsorbent for water treatment or medical care and to provide an adsorbent capable of completely adsorbing an aimed substance within a short time as an adsorbent for medical care. The desired adsorbent is an adsorbent produced from a phenol resin as a starting material and having 0.10 to 0.60 ml/g of volume of fine pores with diameters in a range from 0.02 to 10 μm, a specific surface area in a range from 800 to 3000 m2/g, and an average particle diameter in a range from 0.1 to 0.8 mm. The adsorbent is produced by conducting carbonization of the phenol resin as a starting material at 350 to 550° C., then heating up to 700 to 950° C. at a rate of 5 to 20° C./min, and successively carrying out activation of the obtained carbonized product.

    摘要翻译: 本发明的目的是提供一种吸附剂,其每单位体积的吸附能力高,作为水处理或医疗护理用吸附剂的吸附率高,能够在短时间内提供能够在目标物质内完全吸附的吸附剂,作为吸附剂 医疗保健 所需的吸附剂是由酚醛树脂作为起始材料制成的吸附剂,其直径在0.02-10μm的范围内具有0.10至0.60ml / g的细孔体积,比表面积在800至3000 m 2 / g,平均粒径在0.1〜0.8mm的范围内。 吸附剂通过在350〜550℃下以酚醛树脂作为起始原料进行碳化,然后以5〜20℃/分钟的速度加热至700〜950℃来进行,并依次进行 活化所得碳化产物。