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11.
公开(公告)号:US20220095932A1
公开(公告)日:2022-03-31
申请号:US17507259
申请日:2021-10-21
Applicant: LightLab Imaging, Inc.
Inventor: Joseph M. Schmitt , Joel M. Friedman , Christopher Petroff , Amr Elbasiony
Abstract: A method and apparatus of automatically locating in an image of a blood vessel the lumen boundary at a position in the vessel and from that measuring the diameter of the vessel. From the diameter of the vessel and estimated blood flow rate, a number of clinically significant physiological parameters are then determined and various user displays of interest generated. One use of these images and parameters is to aid the clinician in the placement of a stent. The system, in one embodiment, uses these measurements to allow the clinician to simulate the placement of a stent and to determine the effect of the placement. In addition, from these patient parameters various patient treatments are then performed.
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公开(公告)号:US20140142427A1
公开(公告)日:2014-05-22
申请号:US13792910
申请日:2013-03-11
Applicant: LIGHTLAB IMAGING, INC.
Inventor: Christopher Petroff
CPC classification number: A61B5/0073 , A61B5/0066 , A61B5/0215 , A61B5/6852 , A61B8/12 , A61M39/10 , A61M39/24 , A61M2025/0024 , A61M2025/0035 , A61M2039/242
Abstract: In part, the invention relates to catheters, methods, and blood clearing technologies suitable for use in an optical coherence tomography system. The optical coherence tomography system includes a control system, a probe including a catheter defining a lumen and a rotatable optical fiber located within the lumen, a fluid cartridge holder in communication with the lumen of the probe, a pump to move fluid from the fluid cartridge to the lumen of the probe; and a motor configured to rotate and pull the optical fiber through the lumen of a blood vessel. The pump and the motor are controlled by the control system. The catheter can include a wall that bounds the lumen of the probe, which defines a flush port and includes a valve in fluid communication with the flush port, the valve configured to permit fluid from the lumen to pass through the wall.
Abstract translation: 部分地,本发明涉及适用于光学相干断层摄影系统的导管,方法和血液清除技术。 光学相干断层摄影系统包括控制系统,包括限定内腔的导管和位于内腔内的可旋转光纤的探针,与探针的内腔连通的流体盒保持器,用于将流体从流体盒 到探头的内腔; 以及电动机,其构造成使光纤旋转并拉动通过血管的内腔。 泵和电机由控制系统控制。 导管可以包括限定探针的内腔的壁,该壁限定了冲洗口,并且包括与冲洗口流体连通的阀,所述阀构造成允许来自内腔的流体通过壁。
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13.
公开(公告)号:US12285240B2
公开(公告)日:2025-04-29
申请号:US17968927
申请日:2022-10-19
Applicant: LightLab Imaging, Inc.
Inventor: Joseph M. Schmitt , Joel M. Friedman , Christopher Petroff , Amr Elbasiony
Abstract: A method and apparatus of automatically locating in an image of a blood vessel the lumen boundary at a position in the vessel and from that measuring the diameter of the vessel. From the diameter of the vessel and estimated blood flow rate, a number of clinically significant physiological parameters are then determined and various user displays of interest generated. One use of these images and parameters is to aid the clinician in the placement of a stent. The system, in one embodiment, uses these measurements to allow the clinician to simulate the placement of a stent and to determine the effect of the placement. In addition, from these patient parameters various patient treatments are then performed.
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14.
公开(公告)号:US20240099590A1
公开(公告)日:2024-03-28
申请号:US18523226
申请日:2023-11-29
Applicant: LightLab Imaging, Inc.
Inventor: Joseph M. Schmitt , Joel M. Friedman , Christopher Petroff , Amr Elbasiony
CPC classification number: A61B5/02007 , A61B5/0066 , A61B5/0073 , A61B5/0084
Abstract: A method and apparatus of automatically locating in an image of a blood vessel the lumen boundary at a position in the vessel and from that measuring the diameter of the vessel. From the diameter of the vessel and estimated blood flow rate, a number of clinically significant physiological parameters are then determined and various user displays of interest generated. One use of these images and parameters is to aid the clinician in the placement of a stent. The system, in one embodiment, uses these measurements to allow the clinician to simulate the placement of a stent and to determine the effect of the placement. In addition, from these patient parameters various patient treatments are then performed.
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公开(公告)号:US11058308B2
公开(公告)日:2021-07-13
申请号:US16206033
申请日:2018-11-30
Applicant: LightLab Imaging, Inc.
Inventor: Joseph M. Schmitt , Christopher Petroff
IPC: A61B5/00 , A61B5/0215 , A61B5/02
Abstract: An optical coherence tomography system and method with integrated pressure measurement. In one embodiment the system includes an interferometer including: a wavelength swept laser; a source arm in communication with the wavelength swept laser; a reference arm in communication with a reference reflector, a first photodetector having a signal output; a detector arm in communication with the first photodetector, a probe interlace; a sample arm in communication with a first optical connector of the probe interface; an acquisition and display system comprising: an A/D converter having a signal input in communication with the first photodetector signal output and a signal output; a processor system in communication with the A/D converter signal output; and a display in communication with the processor system; and a probe comprising a pressure sensor and configured for connection to the first optical connector of the probe interface, wherein the pressure transducer comprises an optical pressure transducer.
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公开(公告)号:US10028725B2
公开(公告)日:2018-07-24
申请号:US14768804
申请日:2013-03-11
Applicant: LIGHTLAB IMAGING, INC.
Inventor: Christopher Petroff
Abstract: The invention provides a frictional torque limiter assembly for an imaging core spinning in a patient's body. The torque limiter assembly torsionally isolates the imaging core from a motor that spins the imaging core. An interference fit between a slitted drive tube and a spacer tube acts as a clutch that allows a spinning imaging probe to slow or stop relative to the motor until the motor is stopped, thereby preventing an unsafe condition.
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17.
公开(公告)号:US20140309536A1
公开(公告)日:2014-10-16
申请号:US14117781
申请日:2012-06-25
Applicant: LIGHTLAB IMAGING, INC.
Inventor: Nareak Douk , Christopher Brushett , Stephen M. McCartin , Hirofumi Mizoguchi , Christopher Petersen , Christopher Petroff
CPC classification number: A61B5/0084 , A61B5/0066 , A61M25/0015 , A61M25/003 , A61M25/09 , A61M2025/0183 , Y10T29/49826
Abstract: In part, the invention relates to a catheter suitable for flushing a vessel. The catheter can include separated lumens and components that improve image data collection. In one embodiment, the catheter includes a catheter wall; a distal portion defining a distal lumen (62), the distal lumen having a first end terminating at the distal end of the catheter and a second end (30) terminating at an exit port in the catheter wall; a proximal portion defining proximal lumen (42), the proximal lumen having a first end terminating at the proximal end of the catheter and a second end terminating at a vent port (34) in the catheter wall; and a valve (50,54) positioned adjacent the vent port, the valve permitting fluid to exit the proximal lumen, but preventing particulate matter from the environment from entering the proximal lumen. In one embodiment, the valve comprises a piston (50) and spring (54) located in the proximal lumen (42). In another embodiment, the valve is a filter located in the proximal lumen adjacent the vent port.
Abstract translation: 部分地,本发明涉及适于冲洗血管的导管。 导管可以包括分离的腔和组件,其改善图像数据采集。 在一个实施例中,导管包括导管壁; 限定远端内腔(62)的远侧部分,远端腔具有终止于导管远端的第一端和终止于导管壁中的出口处的第二端(30); 限定近端内腔(42)的近端部分,所述近端内腔具有终止于所述导管近端的第一端和终止于所述导管壁中的通气口(34)的第二端; 以及邻近所述通气口定位的阀门(50,54),所述阀允许流体离开所述近端内腔,但防止来自所述环境的颗粒物质进入所述近端内腔。 在一个实施例中,阀包括位于近端内腔(42)中的活塞(50)和弹簧(54)。 在另一个实施例中,阀是位于邻近排气口的近端腔内的过滤器。
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18.
公开(公告)号:US12150738B2
公开(公告)日:2024-11-26
申请号:US18524893
申请日:2023-11-30
Applicant: LightLab Imaging, Inc.
Inventor: Joseph M. Schmitt , Joel M. Friedman , Christopher Petroff , Amr Elbasiony
Abstract: A method and apparatus of automatically locating in an image of a blood vessel the lumen boundary at a position in the vessel and from that measuring the diameter of the vessel. From the diameter of the vessel and estimated blood flow rate, a number of clinically significant physiological parameters are then determined and various user displays of interest generated. One use of these images and parameters is to aid the clinician in the placement of a stent. The system, in one embodiment, uses these measurements to allow the clinician to simulate the placement of a stent and to determine the effect of the placement. In addition, from these patient parameters various patient treatments are then performed.
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19.
公开(公告)号:US20240177829A1
公开(公告)日:2024-05-30
申请号:US18431302
申请日:2024-02-02
Applicant: LightLab Imaging, Inc.
Inventor: Joseph M. Schmitt , Hiram Bezerra , Christopher Petroff , Ajay Gopinath
CPC classification number: G16H30/20 , A61B5/0066 , A61B5/02007 , A61B5/1076 , A61F2/86 , G16H20/40 , A61B2090/061 , A61F2/82 , A61F2230/0069 , A61F2240/001 , A61F2250/006
Abstract: In part, the invention relates to a method for sizing a stent for placement in a vessel. In one embodiment, the method includes the steps of: dividing the vessel into a plurality of segments, each segment being defined as the space between branches of the vessel; selecting a starting point that appears to have substantially no disease; defining the diameter at this point to be the maximum diameter; calculating the maximal diameter of the next adjacent segment according to a power law; measuring the actual diameter of the next adjacent segment; selecting either the calculated maximum diameter or the measured maximum diameter depending upon which diameter is larger; using the selected maximum diameter to find the maximum diameter of this next segment; iteratively proceeding until the entire length of the vessel is examined; and selecting a stent in response to the diameters of the end proximal and distal segments.
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20.
公开(公告)号:US20240115141A1
公开(公告)日:2024-04-11
申请号:US18524893
申请日:2023-11-30
Applicant: LightLab Imaging, Inc.
Inventor: Joseph M. Schmitt , Joel M. Friedman , Christopher Petroff , Amr Elbasiony
CPC classification number: A61B5/02007 , A61B5/0066 , A61B5/0073 , A61B5/0084
Abstract: A method and apparatus of automatically locating in an image of a blood vessel the lumen boundary at a position in the vessel and from that measuring the diameter of the vessel. From the diameter of the vessel and estimated blood flow rate, a number of clinically significant physiological parameters are then determined and various user displays of interest generated. One use of these images and parameters is to aid the clinician in the placement of a stent. The system, in one embodiment, uses these measurements to allow the clinician to simulate the placement of a stent and to determine the effect of the placement. In addition, from these patient parameters various patient treatments are then performed.
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