-
公开(公告)号：US20140017198A1
公开(公告)日：2014-01-16
申请号：US13934090
申请日：2013-07-02
发明人： Kyla Bjornson , Eda Canales , Jeromy J. Cottell , Kapil Kumar Karki , Ashley Anne Katana , Darryl Kato , Tetsuya Kobayashi , John O. Link , Ruben Martinez , Barton W. Phillips , Hyung-Jung Pyun , Michael Sangi , Adam James Schrier , Dustin Siegel , James G. Taylor , Chinh Viet Tran , Teresa Alejandra Trejo Martin , Randall W. Vivian , Zheng-Yu Yang , Jeff Zablocki , Sheila Zipfel
IPC分类号： C07D498/16 , C07D498/22 , A61K45/06 , A61K31/506 , A61K31/519 , A61K31/4985 , A61K31/4745
CPC分类号： A61K31/498 , A61K31/10 , A61K31/401 , A61K31/4745 , A61K31/4985 , A61K31/506 , A61K31/519 , A61K38/00 , A61K38/06 , A61K38/21 , A61K45/06 , C07D241/36 , C07D403/14 , C07D498/16 , C07D498/22 , C07K5/08 , C07K5/0808 , C07K5/0812 , C07K5/0827 , A61K2300/00
摘要： Compounds of Formula I are disclosed As well as pharmaceutically acceptable salts thereof. Methods of using said compounds and pharmaceutical compositions containing said compounds are also disclosed.
摘要翻译： 公开的式I化合物及其药学上可接受的盐。 还公开了使用所述化合物和含有所述化合物的药物组合物的方法。
-
公开(公告)号：USRE47334E1
公开(公告)日：2019-04-02
申请号：US15715080
申请日：2017-09-25
发明人： Caroline Aciro , Victoria Alexandra Steadman , Simon Neil Pettit , Karine G. Poullennec , Linos Lazarides , David Kenneth Dean , Neil Andrew Dunbar , Adrian John Highton , Andrew John Keats , Dustin Scott Siegel , Kapil Kumar Karki , Adam James Schrier , Petr Jansa , Richard Mackman , Jean Yves Chiva
IPC分类号： A61K38/21 , C07D498/18 , A61K38/12 , A61K45/06 , C07K5/062 , C07D487/18 , C07K5/06 , C07K5/068 , C07K5/078
摘要： Provided are compounds of Formula I: and pharmaceutically acceptable salts and esters thereof. The compounds, compositions, and methods provided are useful for the treatment of virus infections, particularly hepatitis C infections.
-
公开(公告)号：US10246486B2
公开(公告)日：2019-04-02
申请号：US15465492
申请日：2017-03-21
发明人： Caroline Aciro , David Kenneth Dean , Neil Andrew Dunbar , Adrian John Highton , Petr Jansa , Kapil Kumar Karki , Andrew John Keats , Linos Lazarides , Richard Mackman , Simon Neil Pettit , Karine G. Poullennec , Adam James Schrier , Dustin Scott Siegel , Victoria Alexandra Steadman
IPC分类号： A61K38/21 , C07K5/062 , C07D487/08 , C07D498/08 , C07D498/18 , A61K38/12 , A61K39/29 , A61K45/06 , C07K5/02 , C07D471/18 , C07D498/22 , A61K38/55 , A61K31/403 , A61K31/497 , A61K31/504 , A61K31/7056 , A61K31/7072 , C07K5/078 , C07K5/065 , A61K38/05 , C07K5/068 , C07K5/06 , C07K19/00 , A61K38/15 , A61K38/00
摘要： Provided are compounds of Formula I: and pharmaceutically acceptable salts and esters thereof. The compounds, compositions, and methods provided are useful for the treatment of virus infections, particularly hepatitis C infections.
-
公开(公告)号：US09440991B2
公开(公告)日：2016-09-13
申请号：US14576143
申请日：2014-12-18
发明人： Amy Cagulada , Johann Chan , Lina Chan , Denise A. Colby , Kapil Kumar Karki , Darryl Kato , Katie Ann Keaton , Sudha Kondapally , Chris Levins , Adam Littke , Ruben Martinez , Dominika Pcion , Troy Reynolds , Bruce Ross , Michael Sangi , Adam J. Schrier , Pamela Seng , Dustin Siegel , Nathan Shapiro , Donald Tang , James G. Taylor , Jonathan Tripp , Andrew W. Waltman , Lawrence Yu
IPC分类号： C07D403/12 , C07D413/14 , C07D498/16 , C07C227/02 , C07D453/02 , C07C209/00 , C07C51/09 , C07K5/083
CPC分类号： C07D498/18 , C07C51/09 , C07C205/57 , C07C209/00 , C07C227/02 , C07C233/09 , C07C251/12 , C07C255/61 , C07C271/34 , C07C2601/02 , C07D241/44 , C07D403/12 , C07D453/02 , C07D498/16 , C07K5/0808
摘要： The present disclosure provides processes for the preparation of a compound of formula I: which is useful as an antiviral agent. The disclosure also provides compounds and processes for the preparation of the compounds that are synthetic intermediates to the compound of formula I.
-
公开(公告)号：US20150274774A1
公开(公告)日：2015-10-01
申请号：US14740680
申请日：2015-06-16
发明人： Caroline Aciro , David Kenneth Dean , Neil Andrew Dunbar , Adrian John Highton , Petr Jansa , Kapil Kumar Karki , Andrew J. Keats , Linos Lazarides , Richard L. Mackman , Simon N. Pettit , Karine G. Poullennec , Adam James Schrier , Dustin Siegel , Victoria Alexandria Steadman
IPC分类号： C07K5/062
CPC分类号： C07K5/06034 , A61K31/403 , A61K31/497 , A61K31/504 , A61K31/7056 , A61K31/7072 , A61K38/00 , A61K38/05 , A61K38/12 , A61K38/15 , A61K38/21 , A61K38/55 , A61K39/29 , A61K45/06 , C07D471/18 , C07D487/08 , C07D498/08 , C07D498/18 , C07D498/22 , C07K5/02 , C07K5/06052 , C07K5/0606 , C07K5/06078 , C07K5/06086 , C07K5/06139 , C07K5/06191 , C07K19/00 , Y02A50/385 , Y02A50/387 , Y02A50/389 , Y02A50/391 , Y02A50/395 , A61K2300/00
摘要： Provided are compounds of Formula I: and pharmaceutically acceptable salts and esters thereof. The compounds, compositions, and methods provided are useful for the treatment of virus infections, particularly hepatitis C infections.
-
公开(公告)号：US09145441B2
公开(公告)日：2015-09-29
申请号：US13913259
申请日：2013-06-07
申请人： Gilead Sciences, Inc. , Selcia Ltd.
发明人： Caroline Aciro , Victoria Alexandra Steadman , Simon Neil Pettit , Karine G. Poullennec , Linos Lazarides , David Kenneth Dean , Neil Andrew Dunbar , Adrian John Highton , Andrew John Keats , Dustin Scott Siegel , Kapil Kumar Karki , Adam James Schrier , Petr Jansa , Richard Mackman , Jean Yves Chiva
IPC分类号： A61K38/21 , C07K5/062 , C07D487/18 , C07D498/18 , A61K38/12 , A61K45/06
CPC分类号： C07K5/06052 , A61K38/12 , A61K38/21 , A61K45/06 , C07D487/18 , C07D498/18 , C07K5/06086 , C07K5/06139 , C07K5/06191 , Y02A50/385 , Y02A50/387 , Y02A50/389 , Y02A50/391 , Y02A50/395
摘要： Provided are compounds of Formula I: and pharmaceutically acceptable salts and esters thereof. The compounds, compositions, and methods provided are useful for the treatment of virus infections, particularly hepatitis C infections.
-
-
-
-
-
搜索结果
16 条记录 (耗时 0.052 秒)
