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    Security-translator
    12.
    发明申请
    Security-translator 审中-公开
    安全翻译

    公开(公告)号：US20060143449A1

    公开(公告)日：2006-06-29

    申请号：US11285282

    申请日：2005-11-23

    申请人： Martin Groger ,  Markus Fohrenck ,  Christian Scholz

    发明人： Martin Groger ,  Markus Fohrenck ,  Christian Scholz

    IPC分类号： H04L9/00

    CPC分类号： H04L63/0227 ,  H04L63/105 ,  H04L69/40

    摘要： A security translator (STL) that serves for connecting a data network (N2) pertaining to a lower security level to a data network (N1) pertaining to a higher security level examines its own integrity at definite intervals in order to ascertain malfunctions and, where appropriate, to trigger a transition to the secure failure state. The secure failure state consists in the connection from the data network with a lower security level to the data network with a higher security level being interrupted. This is obtained by means of a watchdog circuit (WD1, WD2) which keeps the connection (CTN) between the data network (N2) with a lower security level and the data network (N1) with a higher security level closed as long as it receives regular signs of life and which automatically interrupts the connection if it receives no sign of life over a predetermined period.

    摘要翻译： 用于将属于较低安全级别的数据网络（N 2）连接到属于较高安全级别的数据网络（N 1）的安全转换器（STL）以确定的间隔检查其自己的完整性以便确定故障，并且 在适当情况下，触发转移到安全故障状态。 安全故障状态包括从具有较低安全级别的数据网络到具有较高安全级别中断的数据网络的连接。 这是通过看门狗电路（WD 1，WD 2）获得的，它将数据网络（N 2）与较低安全级别之间的连接（CTN）与安全级别较高的数据网络（N 1）保持 只要它接收到正常的生命迹象，并且如果在预定时段内没有收到生命迹象，则自动中断连接。

    Device for changing the length of the running path of an electromagnetic wave
    15.
    发明授权
    Device for changing the length of the running path of an electromagnetic wave 失效
    用于改变电磁波的运行路径的长度的装置

    公开(公告)号：US06748128B2

    公开(公告)日：2004-06-08

    申请号：US09910124

    申请日：2001-07-20

    申请人： Peter Koch ,  Christian Scholz ,  Ralf Engelhardt

    发明人： Peter Koch ,  Christian Scholz ,  Ralf Engelhardt

    IPC分类号： G02B600

    CPC分类号： G01D5/35303

    摘要： The device serves for changing the length of a running path of an electromagnetic wave. It comprises a wave guide which is wound onto a core. The core is formed in two parts, wherein the distance of the core parts to one another is changeable in order to extend the wave length in a defined manner.

    摘要翻译： 该装置用于改变电磁波的运行路径的长度。 它包括缠绕在芯上的波导。 芯部形成为两部分，其中芯部分彼此的距离是可变的，以便以限定的方式延伸波长。

    Method for the Operation of a Radiotherapy System and a Radiotherapy System
    17.
    发明申请
    Method for the Operation of a Radiotherapy System and a Radiotherapy System 有权
    放射治疗系统和放射治疗系统的运行方法

    公开(公告)号：US20130150646A1

    公开(公告)日：2013-06-13

    申请号：US13684463

    申请日：2012-11-23

    申请人： Christian Scholz

    发明人： Christian Scholz

    IPC分类号： A61N5/10

    CPC分类号： A61N5/1031 ,  A61N5/1047

    摘要： A method for calculating local part radiation doses in a radiotherapy system for applying a total radiation dose in a target volume with several beams is provided. The method includes determining at least one first control plane for controlling the dosing of the beams, determining at least one second control plane for controlling the positioning of the beams, and allocating beams to the first and second control planes. The method also includes, for at least one side of a first control plane, calculating in isolation of the corresponding local part radiation doses of all the beams allocated to the first control plane.

    摘要翻译： 提供了一种用于计算放射治疗系统中的局部部分放射剂量的方法，用于在具有多个光束的目标体积中施加总辐射剂量。 该方法包括确定至少一个第一控制平面以控制光束的计量，确定用于控制光束定位的至少一个第二控制平面，以及将光束分配给第一和第二控制平面。 该方法还包括对于第一控制平面的至少一侧，隔离地分配分配给第一控制平面的所有光束的对应局部部分辐射剂量。

    SlpA as a tool for recombinant protein and enzyme technology
    19.
    发明授权
    SlpA as a tool for recombinant protein and enzyme technology 有权
    SlpA作为重组蛋白和酶技术的工具

    公开(公告)号：US08263086B2

    公开(公告)日：2012-09-11

    申请号：US12436396

    申请日：2009-05-06

    申请人： Christian Scholz ,  Elke Faatz ,  Urban Schmitt ,  Peter Schaarschmidt

    发明人： Christian Scholz ,  Elke Faatz ,  Urban Schmitt ,  Peter Schaarschmidt

    IPC分类号： A61K39/245

    CPC分类号： C12N15/62 ,  C12N9/90 ,  G01N33/536 ,  G01N33/54393 ,  Y02A50/57

    摘要： Disclosed are a recombinant DNA molecule encoding a fusion protein comprising a SlpA chaperone and a target polypeptide wherein human FK506 binding proteins (FKBPs) are excluded as target polypeptides, a corresponding expression vector encoding said fusion protein as well as host cells transformed with said expression vector. Also disclosed are a method for producing the fusion protein, a recombinantly produced fusion protein comprising a SlpA chaperone and a target polypeptide. A further aspect of the invention is the use of the recombinantly produced fusion protein, and a reagent kit containing a recombinantly produced fusion protein comprising a SlpA chaperone and a target polypeptide.

    摘要翻译： 公开了编码包含SlpA伴侣和靶多肽的融合蛋白的重组DNA分子，其中人FK506结合蛋白（FKBPs）被排除为靶多肽，编码所述融合蛋白的相应表达载体以及用所述表达载体转化的宿主细胞 。 还公开了产生融合蛋白的方法，重组产生的包含SlpA伴侣和靶多肽的融合蛋白。 本发明的另一方面是使用重组产生的融合蛋白，以及含有重组产生的包含SlpA伴侣和靶多肽的融合蛋白的试剂盒。

    Fusion protein comprising an Escherichia coli chaperone protein and a human chaperone protein
    20.
    发明授权
    Fusion protein comprising an Escherichia coli chaperone protein and a human chaperone protein 有权
    包含大肠杆菌伴侣蛋白和人伴侣蛋白的融合蛋白

    公开(公告)号：US08247206B2

    公开(公告)日：2012-08-21

    申请号：US13083903

    申请日：2011-04-11

    申请人： Christian Scholz ,  Elke Faatz ,  Peter Schaarschmidt ,  Urban Schmitt

    发明人： Christian Scholz ,  Elke Faatz ,  Peter Schaarschmidt ,  Urban Schmitt

    IPC分类号： C12N9/90 ,  C07K14/00

    CPC分类号： C12N9/90 ,  C07K2319/35

    摘要： The invention discloses the cloning, expression and uses of a chimeric fusion protein with superior chaperone and folding activities compared to the wild type chaperones. This invention relates to a chimeric fusion protein encoded by a recombinant DNA molecule containing nucleotide sequences coding for a polypeptide binding segment of a non-human chaperone protein and nucleotide sequences coding for an FK506 binding protein (FKBP) or an FK506-binding-protein-like domain (FKBP-like domain). In particular, this invention relates to a chimeric fusion protein encoded by a recombinant DNA molecule containing nucleotide sequences coding for a polypeptide binding segment of a non-human chaperone protein and nucleotide sequences coding for a human FKBP type peptidyl-prolyl-cis/trans isomerase (PPIase), methods of producing these chimeric fusion proteins and their uses as folding helpers in the production of other proteins and in the process of the production of vaccines or pharmaceuticals, and as folding helpers for performing immunoassays.

    摘要翻译： 本发明公开了与野生型伴侣相比，具有优异的伴侣和折叠活性的嵌合融合蛋白的克隆，表达和用途。 本发明涉及由含有编码非人伴侣蛋白多肽结合片段的核苷酸序列的重组DNA分子编码的嵌合融合蛋白和编码FK506结合蛋白（FKBP）或FK506-结合蛋白 - 像域（FKBP样域）。 特别地，本发明涉及由包含编码非人伴侣蛋白多肽结合片段的核苷酸序列的重组DNA分子编码的嵌合融合蛋白和编码人FKBP型肽基 - 脯氨酰 - 顺/反异构酶的核苷酸序列 （PPIase），生产这些嵌合融合蛋白的方法及其在生产其他蛋白质和疫苗或药物生产过程中作为折叠助剂的用途，以及用于进行免疫测定的折叠助剂。