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公开(公告)号:US20190128844A1
公开(公告)日:2019-05-02
申请号:US16170766
申请日:2018-10-25
发明人: Bohdan Atamanchuk , Volodimir Bondarenko , Vlad Sergeyev , Henryk Zaleski , Daniel Levin , Mark Piniarski , Igor Kubelik , Qunzhou Bian , Simon Feldberg , Douglas J. Green , Brian Boso , Atin J. Patel
摘要: An ion detection assembly is described that includes a drift chamber, an inlet assembly, and a collector assembly. The drift chamber is formed of substantially non-conductive material and/or semi-conductive material. A patterned resistive trace is deposited on one or more of an interior surface or an exterior surface of the drift chamber. The patterned resistive trace is configured to connect to a source of electrical energy. The inlet assembly and the collector assembly are in fluid communication with the drift chamber. The inlet assembly includes an inlet for receiving a sample, a reaction region for ionizing the sample, and a gate for controlling entrance of the ionized sample to the drift chamber. The collector assembly includes a collector plate for collecting the ionized sample after the ionized sample passes through the drift chamber.
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公开(公告)号:US20170365455A1
公开(公告)日:2017-12-21
申请号:US15634151
申请日:2017-06-27
发明人: Jan Hendrikse , Vladimir Romanov
CPC分类号: H01J49/168 , G01N33/0057 , H01J49/0004 , H01J49/0022 , H01J49/0036 , H01J49/0404 , H01J49/145 , H01J49/24
摘要: A concentric APCI surface ionization probe, supersonic sampling tube, and method for use of the concentric APCI surface ionization probe and supersonic sampling tube are described. In an embodiment, the concentric APCI surface ionization probe includes an outer tube, an inner capillary, and a voltage source coupled to the outer tube and the inner capillary. The inner capillary is housed within and concentric with the outer tube such that ionized gas (e.g., air) travels out of the outer tube, reacts with a sample, and the resulting analyte ions are sucked into the inner capillary. A supersonic sampling tube can include a tube coupled to a mass spectrometer and/or concentric APCI surface ionization probe, where the tube includes at least one de Laval nozzle.
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公开(公告)号:US09778224B2
公开(公告)日:2017-10-03
申请号:US15039586
申请日:2014-11-26
发明人: Igor Kubelik , Simon Feldberg , Bohdan Atamanchuk , Mark Piniarski , Mark Lekhter , Daniel Levin , Vlad Sergeyev , Henryk Zaleski
CPC分类号: G01N27/68 , G01N27/622 , H05H1/2406 , H05H2001/2412 , H05H2001/2468
摘要: An ionization device includes a first electrode comprising a conductive member coated with a dielectric layer. The ionization device also includes a spine extending adjacent to and at least partially along the first electrode. The ionization device further includes a second electrode comprising conductive segments disposed adjacent the first electrode. Each one of the conductive segments contacts the spine at a respective contact location. The dielectric layer of the first electrode separates the conductive member of the first electrode from the spine and the second electrode. The ionization device is configured to create plasma generating locations corresponding to respective crossings of the first electrode and the second electrode.
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公开(公告)号:US09728389B2
公开(公告)日:2017-08-08
申请号:US15036433
申请日:2014-11-14
发明人: Jan Hendrikse , Vladimir Romanov
CPC分类号: H01J49/168 , G01N33/0057 , H01J49/0004 , H01J49/0022 , H01J49/0036 , H01J49/0404 , H01J49/145 , H01J49/24
摘要: A concentric APCI surface ionization probe, supersonic sampling tube, and method for use of the concentric APCI surface ionization probe and supersonic sampling tube are described. In an embodiment, the concentric APCI surface ionization probe includes an outer tube, an inner capillary, and a voltage source coupled to the outer tube and the inner capillary. The inner capillary is housed within and concentric with the outer tube such that ionized gas (e.g., air) travels out of the outer tube, reacts with a sample, and the resulting analyte ions are sucked into the inner capillary. A supersonic sampling tube can include a tube coupled to a mass spectrometer and/or concentric APCI surface ionization probe, where the tube includes at least one de Laval nozzle.
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公开(公告)号:US20150371807A1
公开(公告)日:2015-12-24
申请号:US14764834
申请日:2014-01-30
发明人: Jan Hendrikse , Vladimir Romanov
CPC分类号: H01J27/26 , G01N27/64 , H01J49/142 , H01J49/16 , H01J49/26
摘要: A surface ionization source comprises a tube having a first end, a second end, and an interior bore extending through the tube from the first end to the second end. The first end of the tube is configured to receive a flow of gas and the second end of the tube is configured to direct the flow of gas onto a surface configured to hold an analyte. A radioactive source is at least substantially disposed in the interior bore of the tube. The radioactive source is configured to form ions in the flow of gas as the flow of gas passes through the interior bore. The flow of gas containing the ions is directed onto the analyte to at least partially ionize the analyte.
摘要翻译: 表面电离源包括具有第一端,第二端和从第一端到第二端延伸穿过管的内孔的管。 管的第一端被配置为接收气流,并且管的第二端被配置成将气流引导到构造成保持分析物的表面上。 放射源至少基本上设置在管的内孔中。 放射源被配置成随着气流通过内孔而在气流中形成离子。 含有离子的气体流被引导到被分析物上以至少部分地离子化分析物。
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公开(公告)号:US11506576B2
公开(公告)日:2022-11-22
申请号:US16536994
申请日:2019-08-09
摘要: A trace analyte collection swab having a collection surface at least partially coated with a microscopically tacky substance to enhance pick-up efficiency is described. In embodiments, the truce analyte collection swab comprises a substrate including a surface having a trace analyte collection area and a coating disposed on the surface of the substrate in the trace analyte collection area. The coating is configured to be microscopically adhesive to collect particles of the trace analyte from a surface when the trace analyte collection area is placed against the surface. In one embodiment, the coating comprises Polyisobutylene.
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公开(公告)号:US11307172B2
公开(公告)日:2022-04-19
申请号:US16170766
申请日:2018-10-25
发明人: Bohdan Atamanchuk , Volodimir Bondarenko , Vlad Sergeyev , Henryk Zaleski , Daniel Levin , Mark Piniarski , Igor Kubelik , Qunzhou Bian , Simon Feldberg , Douglas J. Green , Brian Boso , Atin J. Patel
IPC分类号: G01N27/622 , H01J49/00 , H01J49/06 , H01C3/06 , H05K1/11
摘要: An ion detection assembly is described that includes a drift chamber, an inlet assembly, and a collector assembly. The drift chamber is formed of substantially non-conductive material and/or semi-conductive material. A patterned resistive trace is deposited on one or more of an interior surface or an exterior surface of the drift chamber. The patterned resistive trace is configured to connect to a source of electrical energy. The inlet assembly and the collector assembly are in fluid communication with the drift chamber. The inlet assembly includes an inlet for receiving a sample, a reaction region for ionizing the sample, and a gate for controlling entrance of the ionized sample to the drift chamber. The collector assembly includes a collector plate for collecting the ionized sample after the ionized sample passes through the drift chamber.
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公开(公告)号:US11131649B2
公开(公告)日:2021-09-28
申请号:US16280822
申请日:2019-02-20
发明人: Qunzhou Bian , John J. Carroll
IPC分类号: H01J49/00 , H01J49/02 , H01J49/06 , H01J49/04 , G01N27/622 , B08B6/00 , G06K9/00 , G01N23/00
摘要: Method and systems for managing clear-down are provided. The method can include generating a clear-down trigger associated with an ion mobility spectrometer and operating the ion mobility spectrometer in fast clear-down mode in response to the clear-down trigger. Methods and systems can further provide that where the ion mobility spectrometer operates in fast-switching mode, the ion mobility spectrometer alternating a plurality of times between operation according to a positive ion mode and operation according to a negative ion mode, and further operating according to the positive ion mode for less than about 1 second before switching to the operation according to the negative ion mode, and operating according to the negative ion mode for less than about 1 second before switching to the operation according to the positive ion mode.
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公开(公告)号:US09837257B2
公开(公告)日:2017-12-05
申请号:US14900539
申请日:2014-06-19
发明人: Henryk Zaleski
CPC分类号: H01J49/168 , G01N27/622 , H01J27/26
摘要: A corona ionization source assembly and fabrication methods are described that include a fine wire including a wire core including a first material, and a wire coating including a second material, where the wire coating surrounds a portion of the wire core, and the diameter of the wire coating is greater than the diameter of the wire core. Additionally, the fine wire may be coupled to a mounting post. In an implementation, a process for fabricating the corona ionization source assembly that employs the techniques of the present disclosure includes forming a wire core, forming a wire coating that surrounds the wire core, forming a mask layer on at least a portion of the wire coating, etching the wire coating, and removing the mask layer from the wire coating.
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20.
公开(公告)号:US20170023525A1
公开(公告)日:2017-01-26
申请号:US15039586
申请日:2014-11-26
发明人: Igor Kubelik , Simon Feldberg , Bohdan Atamanchuk , Mark Piniarski , Mark Lekhter , Daniel Levin , Vlad Sergeyev , Henryk Zaleski
CPC分类号: G01N27/68 , G01N27/622 , H05H1/2406 , H05H2001/2412 , H05H2001/2468
摘要: An ionization device includes a first electrode comprising a conductive member coated with a dielectric layer. The ionization device also includes a spine extending adjacent to and at least partially along the first electrode. The ionization device further includes a second electrode comprising conductive segments disposed adjacent the first electrode. Each one of the conductive segments contacts the spine at a respective contact location. The dielectric layer of the first electrode separates the conductive member of the first electrode from the spine and the second electrode. The ionization device is configured to create plasma generating locations corresponding to respective crossings of the first electrode and the second electrode.
摘要翻译: 电离装置包括第一电极,其包括涂覆有电介质层的导电构件。 离子化装置还包括沿着第一电极并且至少部分地沿着第一电极延伸的脊柱。 电离装置还包括第二电极,其包括邻近第一电极设置的导电段。 每个导电段在相应的接触位置处接触脊柱。 第一电极的电介质层将第一电极的导电构件与脊柱和第二电极分开。 电离装置被配置成产生对应于第一电极和第二电极的相应交叉点的等离子体产生位置。
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