公开(公告)号：US20070225747A1

公开(公告)日：2007-09-27

申请号：US11682986

申请日：2007-03-07

Applicant: Rodney C. Perkins ,  Nikolai Aljuri ,  Ajit Nair

Inventor： Rodney C. Perkins ,  Nikolai Aljuri ,  Ajit Nair

IPC: A61F2/20 ,  A61M29/00

CPC classification number: A61F2/04 ,  A61B17/12104 ,  A61F2/95 ,  A61F2002/043 ,  A61F2002/068

Abstract: Lung conditions are treated by implanting a flow restrictor in a passageway upstream from a diseased lung segment. The restrictor will create an orifice at the implantation site which inhibits air exchange with the segment to induce controlled atelectasis and/or hypoxia. Controlled atelectasis can induce collapse of the diseased segment with a reduced risk of pneumothorax. Hypoxia can promote gas exchange with non-isolated, healthy regions of the lung even in the absence of lung collapse.

Abstract translation: 通过将流量限制器植入患病肺段上游的通道来治疗肺部疾病。 限流器将在植入部位产生一个孔口，该孔口可抑制与该部分的空气交换以诱导受控的肺不张和/或缺氧。 控制性肺不张可以诱发患病部位的塌陷，降低气胸风险。 即使没有肺塌陷，缺氧也可以促进与非孤立，健康的肺部区域的气体交换。

公开(公告)号：US6084975A

公开(公告)日：2000-07-04

申请号：US080956

申请日：1998-05-19

Applicant: Rodney C. Perkins

Inventor： Rodney C. Perkins

IPC: H04R25/00

CPC classification number: H04R25/606

Abstract: In a hearing system, a transmitting coil is positioned on the promontory centered medial to the umbo of the tympanic membrane while securing the magnet to a surface of said tympanic membrane or to the manubrium of the malleus. The system does not require the permanent placement of components in the auditory canal which would otherwise interfere with normal hearing when the system is not in use.

Abstract translation: 在听力系统中，将发音线圈定位在中心到鼓膜的中心的海角上，同时将磁体固定到鼓膜的表面或锤骨的锤头。 该系统不需要在耳道中永久放置组件，否则当系统不使用时会干扰正常听力。

公开(公告)号：US10555100B2

公开(公告)日：2020-02-04

申请号：US12820776

申请日：2010-06-22

Applicant: Rodney C. Perkins ,  Sunil Puria

Inventor： Rodney C. Perkins ,  Sunil Puria

IPC: H04R25/00

Abstract: A support can be configured for placement in the middle ear to couple a transducer to the round window, such that the transducer can be removed from the round window without damaging the round window. The support can be configured to couple the transducer to the sound window such that the support can be removed from the round window. The support may be configured to decouple the transducer from the round window such that the transducer can be removed from the middle ear of the user, for example when the support is affixed to the middle ear. Removal of the transducer from the middle ear without damaging the round window can allow safe removal of the transducer, for example when the patient wishes to receive MRI imaging.

公开(公告)号：US09154891B2

公开(公告)日：2015-10-06

申请号：US12684073

申请日：2010-01-07

Applicant: Sunil Puria ,  Rodney C. Perkins

Inventor： Sunil Puria ,  Rodney C. Perkins

IPC: H04R25/00 ,  H04R23/00

CPC classification number: H04R25/40 ,  H04R3/04 ,  H04R23/008 ,  H04R25/402 ,  H04R25/453 ,  H04R25/554 ,  H04R25/606 ,  H04R2460/09 ,  H04R2460/13

Abstract: The present invention provides hearing systems and methods that provide an improved high frequency response. The high frequency response improves the signal-to-noise ratio of the hearing system and allows for preservation and transmission of high frequency spatial localization cues.

Abstract translation: 本发明提供了提供改进的高频响应的听觉系统和方法。 高频响应提高了听觉系统的信噪比，并允许高频空间定位线索的保存和传输。

公开(公告)号：US09055379B2

公开(公告)日：2015-06-09

申请号：US12794969

申请日：2010-06-07

Applicant: Sunil Puria ,  Rodney C. Perkins ,  Paul Rucker

Inventor： Sunil Puria ,  Rodney C. Perkins ,  Paul Rucker

IPC: H04R25/00

CPC classification number: H04R25/606 ,  H04R25/453 ,  H04R2225/49

Abstract: An assembly comprising a sound transducer can be implanted in the middle ear in a manner that simplifies surgery. The assembly may comprise a narrow cross-sectional profile such that the assembly can be positioned in the middle ear through an incision in the eardrum, for example without cutting bone. The incision can be closed and electromagnetic energy transmitted through the closed incision to a transducer configured to vibrate the ear in response to the electromagnetic energy. In many embodiments, the sound transducer comprises a speaker positioned in the middle ear, and the sound transducer can couple to vibratory structure of the ear with air so as to simplify surgery. The assembly may be affixed to a substantially fixed structure of the ear, for example the promontory, so as to inhibit user perceivable occlusion and inhibit motion of the assembly, such that the user can perceive clear sound with little occlusion.

Abstract translation: 包括声换能器的组件可以以简化手术的方式植入中耳。 组件可以包括窄的横截面轮廓，使得组件可以通过鼓膜中的切口定位在中耳中，例如不切割骨。 可以关闭切口并且电磁能量通过闭合切口传递到被配置为响应于电磁能量而使耳朵振动的换能器。 在许多实施例中，声音换能器包括位于中耳中的扬声器，并且声音换能器可与空气耦合到耳朵的振动结构，从而简化手术。 组件可以固定到耳朵的基本上固定的结构，例如海角，以便抑制用户可感知的遮挡并且抑制组件的运动，使得用户可以以很少的遮挡感知清晰的声音。

公开(公告)号：US09050094B2

公开(公告)日：2015-06-09

申请号：US12407709

申请日：2009-03-19

Applicant: Nikolai Aljuri ,  Rodney C. Perkins ,  Ryan Olivera ,  Hoang Nguyen ,  Sri Radhakrishnan ,  Niyazi Beyhan

Inventor： Nikolai Aljuri ,  Rodney C. Perkins ,  Ryan Olivera ,  Hoang Nguyen ,  Sri Radhakrishnan ,  Niyazi Beyhan

IPC: A61M16/00 ,  A61B17/12 ,  A61M16/04 ,  A61M25/10

CPC classification number: A61M16/0434 ,  A61B1/2676 ,  A61B5/0084 ,  A61B5/08 ,  A61B5/4836 ,  A61B17/12104 ,  A61B17/12136 ,  A61F2002/043 ,  A61M16/0003 ,  A61M16/0436 ,  A61M16/208 ,  A61M25/10 ,  A61M2016/0027 ,  A61M2016/003 ,  A61M2025/1052 ,  A61M2202/0208 ,  A61M2205/3334 ,  A61M2207/10 ,  Y10T29/49826

Abstract: The volume of a hyperinflated lung compartment is reduced by sealing a distal end of the catheter in an airway feeding the lung compartment. Air passes out of the lung compartment through a passage in the catheter while the patient exhales. A one-way flow element associated with the catheter prevents air from re-entering the lung compartment as the patient inhales. Over time, the pressure of regions surrounding the lung compartment cause it to collapse as the volume of air diminishes. Residual volume reduction effectively results in functional lung volume expansion. Optionally, the lung compartment may be sealed in order to permanently prevent air from re-entering the lung compartment. The invention further discloses a catheter with a transparent occlusion element at its tip that enables examination of the lung passageway through a viewing scope.

Abstract translation: 通过在进入肺隔室的气道中密封导管的远端来减少超膨胀的肺隔室的体积。 当患者呼气时，空气通过导管中的通道从肺隔间通过。 与导管相关联的单向流动元件防止空气在患者吸入时再次进入肺隔室。 随着时间的推移，随着空气体积的减小，肺室周围的区域压力会使其崩溃。 残余体积减少有效地导致功能性肺容积扩张。 任选地，肺隔室可以被密封以便永久地防止空气重新进入肺隔室。 本发明还公开了一种在其顶端具有透明阻塞元件的导管，其能够通过观察范围检查肺通道。

公开(公告)号：US20130245484A1

公开(公告)日：2013-09-19

申请号：US13891719

申请日：2013-05-10

Applicant: Nikolai Aljuri ,  Anthony Wondka ,  George Surjan ,  Kirk Davis ,  Peter Soltesz ,  Rodney C. Perkins

Inventor： Nikolai Aljuri ,  Anthony Wondka ,  George Surjan ,  Kirk Davis ,  Peter Soltesz ,  Rodney C. Perkins

IPC: A61B5/085 ,  A61B5/00 ,  A61B5/087

CPC classification number: A61B5/085 ,  A61B5/055 ,  A61B5/08 ,  A61B5/0813 ,  A61B5/087 ,  A61B5/4836 ,  A61B5/4851 ,  A61B5/6853 ,  A61B5/7278 ,  A61M16/04 ,  A61M16/0404 ,  A61M16/0434 ,  A61M2016/0413

Abstract: Minimally invasive methods, systems and devices are provided for qualitatively and quantitatively assessing collateral ventilation in the lungs. In particular, collateral ventilation of a target compartment within a lung of a patient is assessed by advancement of a catheter through the tracheobronchial tree to a feeding bronchus of the target compartment. The feeding bronchus is occluded by the catheter and a variety of measurements are taken with the use of the catheter in a manner which is of low risk to the patient. Examples of such measurements include but are not limited to flow rate, volume and pressure. These measurements are used to determine the presence of collateral ventilation and to quantify such collateral ventilation.

Abstract translation: 提供了微创方法，系统和装置，用于定性和定量评估肺中的旁路通气。 特别地，通过将​​导管穿过气管支气管树推进到目标隔室的进食支气管来评估患者的肺内的目标隔室的侧支通气。 供血支气管被导管阻塞，并且以对患者的风险低的方式使用导管进行各种测量。 这种测量的实例包括但不限于流量，体积和压力。 这些测量用于确定侧支通气的存在并量化此类旁路通气。

公开(公告)号：US08401214B2

公开(公告)日：2013-03-19

申请号：US12818449

申请日：2010-06-18

Applicant: Rodney C. Perkins ,  Sunil Puria

Inventor： Rodney C. Perkins ,  Sunil Puria

IPC: H04R25/00

CPC classification number: H04R25/606 ,  A61F11/002 ,  H04R1/10 ,  H04R25/60 ,  H04R2460/13

Abstract: An implantable device is configured for placement in the eardrum to transmit an audio signal to a user. The device may be configured to improve transmission of an electromagnetic signal including light energy from an input assembly on a lateral side of eardrum to an output assembly positioned on a medial side of the eardrum, for example at least partially in the middle ear of the user. The output assembly may include a transducer or at least two electrodes configured to stimulate the cochlea, for example. The device may include an opening to transmit the light signal or an optic to transmit the light signal. Alternatively the device may be configured to support a transducer of the output assembly with the eardrum when the device is implanted in the eardrum, such that the eardrum vibrates in response to the signal electromagnetic signal. The electromagnetic signal may include light energy for a magnetic field.

Abstract translation: 可植入装置被配置为放置在鼓膜中以向用户传输音频信号。 该装置可以被配置为改善包括来自鼓膜侧面上的输入组件的光能的电磁信号的传输到定位在鼓膜的内侧上的输出组件，例如至少部分地在使用者的中耳 。 输出组件可以包括例如换能器或构造成刺激耳蜗的至少两个电极。 该装置可以包括用于传输光信号的开口或光学器件以传输光信号。 或者，该装置可以被配置为当该装置植入鼓膜时，用鼓膜支撑输出组件的换能器，使得该鼓膜响应于该信号电磁信号而振动。 电磁信号可以包括用于磁场的光能。

公开(公告)号：US20110152678A1

公开(公告)日：2011-06-23

申请号：US12820547

申请日：2010-06-22

Applicant: Nikolai Aljuri ,  Rodney C. Perkins ,  Niyazi Beyhan

Inventor： Nikolai Aljuri ,  Rodney C. Perkins ,  Niyazi Beyhan

IPC: A61M16/00 ,  A61B6/03

CPC classification number: A61B17/12104 ,  A61B5/055 ,  A61B5/08 ,  A61B5/0813 ,  A61B5/085 ,  A61B5/6853 ,  A61B6/03 ,  A61B6/032 ,  A61B17/1204 ,  A61B17/12136 ,  A61B2017/00022 ,  A61M16/0434 ,  A61M16/208 ,  A61M25/10 ,  A61M2016/0027 ,  A61M2016/003 ,  A61M2025/1052 ,  A61M2205/3303 ,  A61M2205/3334 ,  A61M2205/3344 ,  A61M2210/1035 ,  A61M2230/46

Abstract: The volume of a hyperinflated lung compartment is reduced by sealing a distal end of the catheter in an airway feeding the lung compartment. Air passes out of the lung compartment through a passage in the catheter while the patient exhales. A one-way flow element associated with the catheter prevents air from re-entering the lung compartment as the patient inhales. Over time, the pressure of regions surrounding the lung compartment cause it to collapse as the volume of air diminishes. Residual volume reduction effectively results in functional lung volume expansion. Optionally, the lung compartment may be sealed in order to permanently prevent air from re-entering the lung compartment.

Abstract translation: 通过在进入肺隔室的气道中密封导管的远端来减少超膨胀的肺隔室的体积。 当患者呼气时，空气通过导管中的通道从肺隔间通过。 与导管相关联的单向流动元件防止空气在患者吸入时再次进入肺隔室。 随着时间的推移，随着空气体积的减小，肺室周围的区域压力会使其崩溃。 残余体积减少有效地导致功能性肺容积扩张。 任选地，肺隔室可以被密封以便永久地防止空气重新进入肺隔室。

公开(公告)号：US20110152603A1

公开(公告)日：2011-06-23

申请号：US12822801

申请日：2010-06-24

Applicant: Rodney C. Perkins ,  Sunil Puria

Inventor： Rodney C. Perkins ,  Sunil Puria

IPC: H04R25/00

CPC classification number: H04R25/606 ,  H04R23/008 ,  H04R25/554 ,  H04R2225/023

Abstract: A transducer is configured to couple to the cochlear fluid so as to transmit sound with low amounts of energy, such that feed back to a microphone positioned in the ear canal is inhibited substantially. The cochlear fluid coupled hearing device can allow a user to determine from which side a sound originates with vibration of the cochlea and the user can also receive sound localization cues from the device, as feedback can be substantially inhibited. The transducer may be coupled to the cochlear fluid with a thin membrane disposed between the transducer and the cochlear fluid, for example with a fenestration in the cochlea. In some embodiments, a support coupled to the transducer directly contacts the fluid of the cochlea so as to couple the transducer to the cochlear fluid.

Abstract translation: 换能器被配置成耦合到耳蜗流体，以便以低能量的能量传播声音，从而基本上抑制反馈到定位在耳道中的麦克风的反馈。 耳蜗流体耦合的听觉装置可以允许用户确定声音从耳蜗的振动产生的声音，并且用户也可以从装置接收声音定位提示，因为可以基本上抑制反馈。 换能器可以与设置在换能器和耳蜗流体之间的薄膜耦合到耳蜗流体，例如在耳蜗中开窗。 在一些实施例中，耦合到换能器的支撑件直接接触耳蜗的流体，以将换能器耦合到耳蜗流体。