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公开(公告)号：US09566633B2
公开(公告)日：2017-02-14
申请号：US13678335
申请日：2012-11-15
Applicant: Palmaz Scientific, Inc.
Inventor： Armando Garza , Julio C. Palmaz
CPC classification number: A61F2/915 , A61F2/91 , A61F2210/0076 , A61F2230/0054 , A61F2240/001 , B21D51/16 , B23K26/36 , B23K2101/06
Abstract: An intravascular stent having a hybrid pattern. The hybrid pattern comprises a plurality of circumferentially self-expansible members comprising a plurality of interconnected, geometrically deformable closed cells, adjacent self-expansible members interconnected by a plurality of bridge members linking a first interconnection between two closed cells in a first self-expansible member to a second interconnection between two closed cells in a second self-expansible member, wherein the second interconnection is circumferentially offset and non-adjacent to the first interconnection.
Abstract translation: 具有混合型式的血管内支架。 混合图案包括多个周向自膨胀构件，其包括多个互连的几何可变形闭孔，相邻的可自膨胀构件通过多个桥构件互连，所述多个桥构件将第一自膨胀构件中的两个闭孔之间的第一互连 到第二自扩张构件中的两个闭孔之间的第二互连，其中所述第二互连沿周向偏移并且不与所述第一互连相邻。
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12.发明申请DEVICE FOR IN VIVO DELIVERY OF BIOACTIVE AGENTS AND METHOD OF MANUFACTURE THEREOF 审中-公开用于生物体药物输送的装置及其制造方法公开(公告)号：US20150342761A1
公开(公告)日：2015-12-03
申请号：US14825526
申请日：2015-08-13
Applicant: Advanced Bio Prosthetic Surfaces, Ltd., a wholly owned subsidiary of Palmaz Scientific, Inc.
Inventor： Denes MARTON , Steven R. BAILEY , Christopher E. BANAS , Christoper T. BOYLE
CPC classification number: A61B5/076 , A61B5/01 , A61B5/02055 , A61B5/021 , A61B5/0215 , A61B5/026 , A61B5/4839 , A61B5/6862 , A61B5/6876 , A61F2/07 , A61F2/82 , A61F2/86 , A61F2/91 , A61F2/915 , A61F2002/91533 , A61F2002/91541 , A61F2002/91558 , A61F2210/0076 , A61F2240/001 , A61F2250/0001 , A61F2250/0067 , A61F2250/0068 , A61L27/04 , A61L27/54 , A61L31/022 , A61L31/16 , A61L2300/602
Abstract: The drug eluting device consists of an implantable structural element for in vivo controlled delivery of bioactive active agents to a situs in a body. The implantable structural element may be configured as an implantable prosthesis, such as an endoluminal stent, cardiac valve, osteal implant or the like, which serves a dual function of being prosthetic and a carrier for a bioactive agent. Control over elution of the bioactive agents occurs through a plurality of cantilever-like cover members which prevent drug elution until an endogenous or exogenous stimulus causes the cover members to open and permit drug elution.
Abstract translation: 药物洗脱装置由可植入的结构元件组成，用于体内控制递送生物活性剂到体内的部位。 可植入结构元件可以被配置为可植入假体，例如腔内支架，心脏瓣膜，骨植入物等，其用作假体和用于生物活性剂的载体的双重功能。 控制生物活性剂的洗脱通过多个悬臂状覆盖构件发生，其阻止药物洗脱，直到内源性或外源性刺激使盖构件打开并允许药物洗脱。
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13.发明申请公开(公告)号：US20140294910A1
公开(公告)日：2014-10-02
申请号：US14219924
申请日：2014-03-19
Applicant: PALMAZ SCIENTIFIC, INC.
Inventor： Julio C. Palmaz
IPC: A61L31/16
CPC classification number: A61L31/16 , A61F2/0077 , A61F2/02 , A61L2400/18 , C23C14/042 , C23C14/24 , C23C14/5873 , G03F7/20
Abstract: An implantable biocompatible material includes one or more vacuum deposited layers of biocompatible materials deposited upon a biocompatible base material. At least a top most vacuum deposited layer includes a homogeneous molecular pattern of distribution along the surface thereof and comprises a patterned array of geometric physiologically functional features.
Abstract translation: 可植入生物相容性材料包括沉积在生物相容性基材上的生物相容性材料的一个或多个真空沉积层。 至少最顶层的真空沉积层包括沿其表面分布的均匀分子图案，并且包括几何生理功能特征的图案化阵列。
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公开(公告)号：US20130334032A1
公开(公告)日：2013-12-19
申请号：US13908933
申请日：2013-06-03
Applicant: Advanced Bio Prosthetic Surfaces, Ltd. a wholly owned subsidiary of Palmaz Scientific, Inc.
Inventor： Julio C. Palmaz , Christopher T. Boyle
IPC: C23C14/35
CPC classification number: C23C14/35 , A61F2/0077 , A61F2/06 , A61F2/91 , A61F2/915 , A61F2002/91533 , A61F2002/9155 , A61F2002/91558 , A61F2210/0076 , A61F2240/001 , Y10T29/49812 , Y10T29/49885 , Y10T29/4998 , Y10T29/49982 , Y10T29/49995
Abstract: Implantable medical grafts fabricated of metallic or pseudometallic films of biocompatible materials having a plurality of microperforations passing through the film in a pattern that imparts fabric-like qualities to the graft or permits the geometric deformation of the graft. The implantable graft is preferably fabricated by vacuum deposition of metallic and/or pseudometallic materials into either single or multi-layered structures with the plurality of microperforations either being formed during deposition or after deposition by selective removal of sections of the deposited film. The implantable medical grafts are suitable for use as endoluminal or surgical grafts and may be used as vascular grafts, stent-grafts, skin grafts, shunts, bone grafts, surgical patches, non-vascular conduits, valvular leaflets, filters, occlusion membranes, artificial sphincters, tendons and ligaments.
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公开(公告)号：US20170035589A1
公开(公告)日：2017-02-09
申请号：US15149788
申请日：2016-05-09
Applicant: PALMAZ SCIENTIFIC, INC.
Inventor： Scott Carpenter , Michael POOR
IPC: A61F2/915
Abstract: A monolithic device comprising an ultra-dense stent cell pattern including a plurality of structural members that diverts the majority of blood flow without restricting blood flow completely. The method of making medical devices comprises vapor depositing an initial film onto a substrate, laser cutting a device pattern through the initial film, electropolishing the patterned device while disposed on the substrate, and releasing the patterned device from the substrate.
Abstract translation: 一种整体式装置，包括超密度支架细胞图案，其包括多个结构构件，其将大部分血流转移而不会完全限制血液流动。 制造医疗装置的方法包括将初始膜蒸镀沉积到基底上，通过初始膜激光切割器件图案，在设置在衬底上的同时对图案化器件进行电解抛光，以及将图案化器件从衬底上释放出来。
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Patent Agency Ranking
16.发明授权公开(公告)号：US09421100B2
公开(公告)日：2016-08-23
申请号：US14665817
申请日：2015-03-23
Inventor： Steven R. Bailey , Christopher T. Boyle
CPC classification number: A61F2/2412 , A61F2/07 , A61F2/2418 , A61F2/243 , A61F2/2436 , A61F2/2469 , A61F2/2475 , A61F2002/9522 , A61F2220/0008 , A61F2220/0016 , A61F2230/005 , A61F2230/0054 , A61F2230/0078
Abstract: This invention relates to prosthetic cardiac and venous valves and a single catheter device and minimally invasive techniques for percutaneous and transluminal valvuloplasty and prosthetic valve implantation.
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17.发明申请公开(公告)号：US20150366667A1
公开(公告)日：2015-12-24
申请号：US14665817
申请日：2015-03-23
Inventor： Steven R. Bailey , Christopher T. Boyle
CPC classification number: A61F2/2412 , A61F2/07 , A61F2/2418 , A61F2/243 , A61F2/2436 , A61F2/2469 , A61F2/2475 , A61F2002/9522 , A61F2220/0008 , A61F2220/0016 , A61F2230/005 , A61F2230/0054 , A61F2230/0078
Abstract: This invention relates to prosthetic cardiac and venous valves and a single catheter device and minimally invasive techniques for percutaneous and transluminal valvuloplasty and prosthetic valve implantation.
Abstract translation: 本发明涉及假体心脏和静脉瓣膜以及用于经皮和腔内瓣膜成形术和人工瓣膜植入的单一导管装置和微创技术。
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18.发明申请STENT-GRAFT WITH PROXIMAL AND DISTAL ATTACHMENT, DELIVERY CATHETER AND METHODS OF MAKING SAME 审中-公开具有临时和远程连接的STENT-GRAFT，传送导管及其制造方法公开(公告)号：US20140343658A1
公开(公告)日：2014-11-20
申请号：US14288284
申请日：2014-05-27
Applicant: Advanced Bio Prosthetic Surfaces, Ltd., a wholly owned subsidiary of Palmaz Scientific, Inc.
Inventor： Daniel D. Sims , Jeffrey N. Steinmetz , Conor P. Mullens
CPC classification number: A61F2/90 , A61F2/07 , A61F2/91 , A61F2/95 , A61F2/966 , A61F2002/075 , A61F2240/001 , A61L31/022 , Y10T29/49947
Abstract: A metallic or pseudometallic covered stent in which the stent component and the cover component are each fabricated of biocompatible metallic or pseudometallic materials, in which the cover and the stent are joined by at least one juncture at each of a proximal and distal end of the stent and the cover. A method of joining the stent and the cover is also disclosed.
Abstract translation: 金属或假金属被覆盖的支架，其中支架部件和盖部件各自由生物相容的金属或假金属材料制成，其中盖和支架通过支架的近端和远端中的每一个处至少一个接合处连接 和封面。 还公开了一种连接支架和盖子的方法。
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19.发明申请ENDOLUMINAL IMPLANTABLE SURFACES, STENTS, AND GRAFTS AND METHOD OF MAKING THE SAME 审中-公开内膜可植入性表面，手术和手术及其制造方法公开(公告)号：US20140332499A1
公开(公告)日：2014-11-13
申请号：US14276741
申请日：2014-05-13
Applicant: PALMAZ SCIENTIFIC, INC.
Inventor： Julio C. Palmaz , Armando Garza
CPC classification number: A61F2/07 , A61F2/0077 , A61F2/91 , A61F2002/0081 , A61F2002/9522 , A61F2210/0076 , A61F2240/001 , B23K26/0624 , B23K26/146 , B23K26/355 , B23K26/364 , B29C2035/0838 , C23F4/00
Abstract: A method of manufacturing an endoluminal implantable surface, stent, or graft includes the steps of providing an endoluminal implantable surface, stent, or graft having an inner wall surface, an outer wall surface, and a wall thickness and forming a pattern design into the endoluminal implantable surface, stent, or graft. At least one groove is created in the inner surface of the intravascular stent by applying a laser machining method to the inner surface.
Abstract translation: 制造内腔可植入表面，支架或移植物的方法包括以下步骤：提供具有内壁表面，外壁表面和壁厚的腔内可植入表面，支架或移植物，并将模式设计形成到腔内 植入式表面，支架或移植物。 通过对内表面施加激光加工方法，在血管内支架的内表面中形成至少一个凹槽。
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20.发明申请IMPLANTABLE MATERIALS HAVING ENGINEERED SURFACES COMPRISING A PATTERN OF FEATURES AND METHOD OF MAKING SAME 有权具有包含特征图案的工程表面的可植入材料及其制造方法公开(公告)号：US20140314992A1
公开(公告)日：2014-10-23
申请号：US14256674
申请日：2014-04-18
Applicant: ADVANCED BIO PROSTHETIC SURFACES, LTD., a wholly owned subsidiary of Palmaz Scientific, Inc.
Inventor： Julio C. PALMAZ , Eugene A. SPRAGUE
IPC: A61L31/02
CPC classification number: A61L31/028 , A61F2/00 , A61F2/0077 , A61F2/02 , A61F2002/0086 , A61F2310/00616 , A61L31/022 , A61L31/024 , Y10T428/24355
Abstract: Implantable materials having defined patterns of affinity regions for binding endothelial cells and providing for directed endothelial cell migration across the surface of the material. The affinity regions include photochemically altered regions of a material surface and physical members patterned on the material surface that exhibit a greater affinity for endothelial cell binding and migration than the remaining regions of the material surface.
Abstract translation: 可植入材料具有限定的内皮细胞结合亲和区域的图案，并提供穿过该材料表面的定向内皮细胞迁移。 亲和性区域包括材料表面的光化学改变的区域和在材料表面上图案化的物理构件，其对于内皮细胞结合和迁移显示出比材料表面的剩余区域更大的亲和力。
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