SENSITIVE AND RAPID DETERMINATION OF ANTIMICROBIAL SUSCEPTIBILITY
    11.
    发明申请
    SENSITIVE AND RAPID DETERMINATION OF ANTIMICROBIAL SUSCEPTIBILITY 有权
    敏感和快速确定抗微生物的可疑性

    公开(公告)号:US20100136570A1

    公开(公告)日:2010-06-03

    申请号:US12702210

    申请日:2010-02-08

    Abstract: The present invention relates to moving microorganisms to a surface, where they are grown in the presence and absence of antimicrobials, and by monitoring the growth of the microorganisms over time in the two conditions, their susceptibility to the antimicrobials can be determined. The microorganisms can be moved to the surface through electrophoresis, centrifugation or filtration. When the movement involves electrophoresis, the presence of oxidizing and reducing reagents lowers the voltage at which electrophoretic force can be generated and allows a broader range of means by which the target can be detected. Monitoring can comprise optical detection, and most conveniently includes the detection of individual microorganisms. The microorganisms can be stained in order to give information about their response to antimicrobials.

    Abstract translation: 本发明涉及将微生物移动到表面,其中它们在存在和不存在抗微生物剂的情况下生长,并且通过在两个条件下随时间监测微生物的生长,可以确定它们对抗微生物剂的敏感性。 微生物可通过电泳,离心或过滤移至表面。 当运动涉及电泳时,氧化和还原剂的存在降低了可以产生电泳力的电压,并允许可以检测目标的更宽范围的方法。 监测可以包括光学检测,并且最方便地包括检测单个微生物。 微生物可以被染色以便提供关于它们对抗微生物剂的反应的信息。

    Sensitive and rapid determination of antimicrobial susceptibility
    12.
    发明授权
    Sensitive and rapid determination of antimicrobial susceptibility 有权
    敏感和快速测定抗菌药物敏感性

    公开(公告)号:US07687239B2

    公开(公告)日:2010-03-30

    申请号:US10888828

    申请日:2004-07-08

    Abstract: The present invention relates to moving microorganisms to a surface, where they are grown in the presence and absence of antimicrobials, and by monitoring the growth of the microorganisms over time in the two conditions, their susceptibility to the antimicrobials can be determined. The microorganisms can be moved to the surface through electrophoresis, centrifugation or filtration. When the movement involves electrophoresis, the presence of oxidizing and reducing reagents lowers the voltage at which electrophoretic force can be generated and allows a broader range of means by which the target can be detected. Monitoring can comprise optical detection, and most conveniently includes the detection of individual microorganisms. The microorganisms can be stained in order to give information about their response to antimicrobials.

    Abstract translation: 本发明涉及将微生物移动到表面,其中它们在存在和不存在抗微生物剂的情况下生长,并且通过在两个条件下随时间监测微生物的生长,可以确定它们对抗微生物剂的敏感性。 微生物可通过电泳,离心或过滤移至表面。 当运动涉及电泳时,氧化和还原剂的存在降低了可以产生电泳力的电压,并允许可以检测目标的更宽范围的方法。 监测可以包括光学检测,并且最方便地包括检测单个微生物。 微生物可以被染色以便提供关于它们对抗微生物剂的反应的信息。

    RAPID DETECTION OF MICROORGANISMS IN FLUIDS
    13.
    发明申请
    RAPID DETECTION OF MICROORGANISMS IN FLUIDS 审中-公开
    快速检测流体中的微生物

    公开(公告)号:US20080153125A1

    公开(公告)日:2008-06-26

    申请号:US11937992

    申请日:2007-11-09

    CPC classification number: C12M23/12 C12M23/22 C12M25/04 C12M41/36 C12Q1/04

    Abstract: A system for the rapid detection of microbial contamination in a fluid sample such as water, involving the use of a filter material having a surface adapted to receive the sample in order to retain substantially all microbes from the sample on the filter surface under conditions that minimize the potential for contamination from sources other than the sample itself, and in a manner that permits the filter surface to be incubated in order to grow viable microbes contained thereon, in combination with a growth medium and an analytic instrument to permit analysis of the filter surface, within a predetermined incubation period, in order to determine whether the growth onset of viable microbes that may be present on the surface has begun.

    Abstract translation: 一种用于快速检测诸如水的流体样品中的微生物污染的系统,其涉及使用具有适于接收样品的表面的过滤材料,以便在最小化条件下将来自样品的基本上所有微生物从样品保持在过滤表面上 来自除了样品本身之外的来源的污染的可能性,并且以允许过滤表面孵育以便生长包含在其上的活的微生物的方式与生长培养基和分析仪器组合以允许分析过滤表面 在预定的潜伏期内,以确定是否开始可能存在于表面上的活微生物的生长发生。

    Chelating ionic liquids for magnesium battery electrolytes and systems

    公开(公告)号:US10147971B2

    公开(公告)日:2018-12-04

    申请号:US15942741

    申请日:2018-04-02

    Abstract: Ionic liquids suitable for use in magnesium batteries are disclosed. In an exemplary embodiment, a rechargeable magnesium battery comprises an anode electrode, a cathode electrode, and a chelating ionic liquid solution in contact therewith. The chelating ionic liquid may comprise at least one cation, at least one anion, and at least one soluble, magnesium salt. The magnesium salt may comprise MgX2, wherein X comprises at least one of Cl—, Br—, I—, TFSI—, FSI—, ClO4—, BF4—, PF6—, RSO3— (wherein R consists of at least one of an alkyl or aryl group), RCO2— (wherein R consists of at least one of an alkyl or aryl group), alkyl borides, alkyl borates, AlCl4—, AlXaRb— (wherein the sum of subscripts a and b is 4, X consists of a halide, and R consists of at least one of an alkyl or aryl group), carboranes, or hexamethyldisilazide.

    SIMULTANEOUS RAPID DETECTION OF MICROBES
    19.
    发明申请
    SIMULTANEOUS RAPID DETECTION OF MICROBES 审中-公开
    同时快速检测微生物

    公开(公告)号:US20080261229A1

    公开(公告)日:2008-10-23

    申请号:US12103282

    申请日:2008-04-15

    CPC classification number: C12N1/14 C12N1/38 C12Q1/04 C12Q1/045

    Abstract: The invention includes a method of simultaneously detecting the presence or absence of more than one microbe class (e.g., bacteria, yeast, and mold) in a sample. The method can include the step of applying a sample suspected of containing more than one microbe class to a growth medium, optionally fragmenting the sample, associating the sample with a labeling agent, and simultaneously detecting the presence or absence of each microbe class by detection of the labeling agent.

    Abstract translation: 本发明包括同时检测样品中多于一种微生物类(例如细菌,酵母和霉菌)的存在或不存在的方法。 该方法可以包括将怀疑含有多于一种微生物类的样品施用于生长培养基的步骤,任选地将样品片段化,使样品与标记试剂结合,并通过检测样品同时检测每种微生物等级的存在或不存在 标签代理。

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