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    Biopsy cavity marking device and method
    13.
    发明授权
    Biopsy cavity marking device and method 有权
    活检腔标记装置及方法

    公开(公告)号：US08320994B2

    公开(公告)日：2012-11-27

    申请号：US10960618

    申请日：2004-10-06

    申请人： D. Laksen Sirimanne ,  Douglas S. Sutton ,  Natalie V. Fawzi ,  Gail Lebovic

    发明人： D. Laksen Sirimanne ,  Douglas S. Sutton ,  Natalie V. Fawzi ,  Gail Lebovic

    IPC分类号： A61B6/00

    CPC分类号： A61B8/481 ,  A61B90/39 ,  A61B2090/3908 ,  A61B2090/3987 ,  A61K49/006 ,  A61K49/222

    摘要： These are biopsy cavity marking devices and methods. More particularly, upon insertion into a body, the cavity marking device and method enable one to determine the center, orientation, and periphery of the biopsy cavity by radiographic, mammographic, echogenic, or other non-invasive imaging techniques. Also, the device contains a detectable marker. The device may be combined with various substances enhancing the radiopaque, mammographic, or echogenic characteristics of the marker or the body allowing it to be observed by any non-invasive imaging techniques. This is further a method of marking a biopsy cavity using a bioabsorbable material and a detectable marker in conjunction with the material. The method also may combine any of the features as described with the device.

    摘要翻译： 这些是活检腔标记装置和方法。 更具体地，在插入体中时，腔标记装置和方法使得能够通过放射照相，乳房造影，回声或其它非侵入性成像技术来确定活检腔的中心，取向和周边。 此外，该装置含有可检测标记。 该装置可以与增强标记物或身体的不透射线，乳房摄影或回声特征的各种物质组合，从而允许通过任何非侵入性成像技术来观察。 这进一步地使用生物可吸收材料和与材料结合的可检测标记来标记活检腔的方法。 该方法还可以组合与所述设备一起描述的任何特征。

    DEVICE AND METHOD FOR SAFE LOCATION AND MARKING OF A BIOPSY CAVITY
    14.
    发明申请
    DEVICE AND METHOD FOR SAFE LOCATION AND MARKING OF A BIOPSY CAVITY 有权
    用于安全定位和标记生物密度的装置和方法

    公开(公告)号：US20100234726A1

    公开(公告)日：2010-09-16

    申请号：US12777710

    申请日：2010-05-11

    申请人： D. Laksen Sirimanne ,  Natalie V. Fawzi ,  Douglas S. Sutton ,  Gail S. Lebovic ,  Stanley R. Conston ,  Peter M. Wilson ,  Anne B. Morrissey ,  Mary Elizabeth Bush

    发明人： D. Laksen Sirimanne ,  Natalie V. Fawzi ,  Douglas S. Sutton ,  Gail S. Lebovic ,  Stanley R. Conston ,  Peter M. Wilson ,  Anne B. Morrissey ,  Mary Elizabeth Bush

    IPC分类号： A61B5/05

    CPC分类号： A61K49/006 ,  A61B90/39 ,  A61B2017/00539 ,  A61B2090/3925 ,  A61B2090/3966 ,  A61B2090/3987 ,  A61B2090/3995

    摘要： Cavity and sentinel lymph node marking 412 devices, marker delivery devices, and methods are disclosed. More particularly, upon insertion into a body, the cavity marking device and method enable one to determine the center, orientation, and periphery of the cavity by radiographic, mammography, echogenic, or other noninvasive imaging techniques. A composition and method are disclosed for locating the sentinel lymph node in a mammalian body to determine if cancerous cells have spread thereto. The composition is preferably a fluid composition consisting of a carrier fluid and some type of contrast agent; alternatively, the contrast agent may itself be a fluid and therefore not need a separate carrier fluid. This composition is capable of (1) deposition in or around a lesion and migration to and accumulation in the associated sentinel node, and (2) remote detection via any number of noninvasive techniques. Also disclosed is a method for remotely detecting the location of a sentinel node by (1) depositing a remotely detectable fluid in or around a lesion for migration to and accumulation in the associated sentinel node and (2) remotely detecting the location of that node with a minimum of trauma and toxicity to the patient. The composition and method may serve to mark a biopsy cavity, as well as mark the sentinel lymph node. The marking methods also may combine any of the features as described with the marking device and delivery device.

    摘要翻译： 公开了腔和前哨淋巴结标记412装置，标记递送装置和方法。 更具体地说，在插入体中时，腔标记装置和方法使得能够通过放射照相，乳房X线照相术，回声或其它非侵入性成像技术确定腔的中心，取向和周边。 公开了用于在哺乳动物体内定位前哨淋巴结的组合物和方法，以确定癌细胞是否已扩散到其上。 组合物优选是由载体流体和某种类型的造影剂组成的流体组合物; 或者，造影剂本身可以是流体，因此不需要单独的载体流体。 该组合物能够（1）沉积在病变中或周围，并且迁移到相关的前哨淋巴结中并累积在相关的前哨淋巴结中，以及（2）通过任何数量的无创技术的远程检测。 还公开了一种用于通过以下步骤远程检测前哨节点的位置的方法：（1）在病变中或周围沉积可远程检测的流体，以便迁移到相关联的前哨节点并累积在相关联的哨兵节点中;以及（2）远程检测该节点的位置， 对患者的至少创伤和毒性。 组合物和方法可用于标记活检腔，以及标记前哨淋巴结。 标记方法还可以将所描述的特征与标记装置和递送装置组合。

    Subcutaneous cavity marking device and method
    16.
    发明授权
    Subcutaneous cavity marking device and method 有权
    皮下腔标记装置及方法

    公开(公告)号：US06371904B1

    公开(公告)日：2002-04-16

    申请号：US09347185

    申请日：1999-07-02

    申请人： D. Laksen Sirimanne ,  Natalie V. Fawzi ,  Douglas S. Sutton ,  Gail Lebovic ,  Stanley R. Conston ,  Peter M. Wilson

    发明人： D. Laksen Sirimanne ,  Natalie V. Fawzi ,  Douglas S. Sutton ,  Gail Lebovic ,  Stanley R. Conston ,  Peter M. Wilson

    IPC分类号： A61N500

    CPC分类号： A61K49/006 ,  A61B90/39 ,  A61B2017/00539 ,  A61B2090/3925 ,  A61B2090/3966 ,  A61B2090/3987 ,  A61B2090/3995

    摘要： This is a subcutaneous cavity marking devices and methods. More particularly, upon insertion into a body, the cavity marking device and method enable one to determine the center, orientation, and periphery of the cavity by radiographic, mammographic, echogenic, or other non-invasive imaging techniques. Also, the device contains a bioabsorbable or non-bioabsorbable marker. The device may be combined with various substances enhancing the radiopaque, mammographic, or echogenic characteristics of the marker or the body allowing it to be observed by any non-invasive imaging techniques. This is further a method of marking a subcutaneous cavity using a bioabsorbable material and a bioabsorbable or non-bioabsorbable marker in conjunction with the material. The method also may combine any of the features as described with the device.

    摘要翻译： 这是皮下腔标记装置和方法。 更具体地说，在插入体中时，腔标记装置和方法使得能够通过放射照相，乳房X线照相，回声或其它非侵入性成像技术确定腔的中心，取向和周边。 而且，该装置包含生物可吸收或非生物可吸收标记物。 该装置可以与增强标记物或身体的不透射线，乳房摄影或回声特征的各种物质组合，从而允许通过任何非侵入性成像技术来观察。 这进一步地使用生物可吸收材料和与该材料结合的生物可吸收或非生物可吸收标记来标记皮下腔的方法。 该方法还可以组合与所述设备一起描述的任何特征。