公开(公告)号：US20160113667A1

公开(公告)日：2016-04-28

申请号：US14928440

申请日：2015-10-30

Applicant: University of Washington through its Center for Commercialization

Inventor： Michael Bailey ,  Bryan Cunitz ,  Barbrina Dunmire

IPC: A61B17/225 ,  A61B6/00 ,  A61B6/03 ,  A61B8/08

CPC classification number: A61B17/225 ,  A61B5/055 ,  A61B5/7232 ,  A61B6/03 ,  A61B6/485 ,  A61B8/085 ,  A61B8/488 ,  A61B17/2256 ,  A61B2017/22005 ,  A61B2090/378 ,  A61N7/00 ,  A61N2007/0004 ,  A61N2007/0052 ,  A61N2007/0082 ,  G01S7/52071 ,  G01S15/899

Abstract: Described herein are methods and apparatus for detecting stones by ultrasound, in which the ultrasound reflections from a stone are preferentially selected and accentuated relative to the ultrasound reflections from blood or tissue. Also described herein are methods and apparatus for applying pushing ultrasound to in vivo stones or other objects, to facilitate the removal of such in vivo objects.

公开(公告)号：US09301729B2

公开(公告)日：2016-04-05

申请号：US13388797

申请日：2010-08-05

Applicant: Naoko Sakamoto ,  Jun Takeda ,  Atsushi Asahina

Inventor： Naoko Sakamoto ,  Jun Takeda ,  Atsushi Asahina

IPC: A61B8/00 ,  A61B8/08 ,  A61N7/00 ,  A61B17/17

CPC classification number: A61B8/0875 ,  A61B8/5207 ,  A61B17/1703 ,  A61N7/00 ,  A61N2007/0013 ,  A61N2007/0052 ,  A61N2007/0073

Abstract: Provided is an ultrasound fracture detection device capable of accurately irradiating an ultrasound pulse to a target object, the device being characterized by being provided with an ultrasound wave irradiating transducer, a signal receiving transducer which receives a reflected wave of an ultrasound wave irradiated from the ultrasound wave irradiating transducer, a signal, storage unit which stores a received signal, and a display unit which displays an analysis program that analyzes a stored signal, a determination program that performs determination from the result of the analysis and/or performs determination from the stored signal, and the result of the analysis and/or the result of the determination, wherein the determination program performs the determination using that information relating to the received signal varies depending on the reflector within a living organism.

Abstract translation: 本发明提供一种能够将目标物体精确地照射超声脉冲的超声波断裂检测装置，其特征在于，设置有超声波照射换能器，接收从超声波照射的超声波的反射波的信号接收换能器 波长照射换能器，存储接收信号的信号存储单元和显示分析存储信号的分析程序的显示单元，从分析结果执行确定和/或从所存储的信号执行确定的确定程序 信号，以及分析结果和/或确定结果，其中确定程序使用与接收信号相关的信息来执行确定，这取决于活体内的反射器。

公开(公告)号：US09262252B2

公开(公告)日：2016-02-16

申请号：US14050570

申请日：2013-10-10

Applicant: St. Jude Medical, Atrial Fibrillation Division, Inc.

Inventor： Bruce E. Kirkpatrick ,  Timothy E. Ciciarelli

IPC: G06F11/07 ,  A61B18/12 ,  A61B5/042 ,  A61B18/14 ,  A61B17/00 ,  A61B18/00 ,  A61N7/02

CPC classification number: A61B17/320068 ,  A61B5/0422 ,  A61B18/1206 ,  A61B18/1492 ,  A61B2017/00022 ,  A61B2017/00199 ,  A61B2017/00221 ,  A61B2017/00482 ,  A61B2018/00988 ,  A61B2034/256 ,  A61N7/02 ,  A61N7/022 ,  A61N2007/0052 ,  G05B19/042 ,  G05B2219/23278 ,  G06F11/0778

Abstract: A medical device for diagnosis or treatment of tissue is disclosed. The device includes an electronically-controlled tool configured for diagnosis or treatment, an electrical connector, and a computer readable memory. The electrical connector is configured for connection with an electronic control unit and configured to receive control signals, including signals concerning the operation of the tool, from the electronic control unit. The computer readable memory is accessible through the connector. The memory can include a set of programming instructions for control of the tool, and the programming instructions can be configured to be downloadable from the memory upon connection of the electrical connector with the electronic control unit. A system is also disclosed in which the electronic control unit is configured to transmit a data log from memory in the electronic control unit to the memory in the medical device upon the occurrence or detection of a predetermined event.

公开(公告)号：US20160022490A1

公开(公告)日：2016-01-28

申请号：US14427460

申请日：2013-11-12

Applicant: SABANCI UNIVERSITY

Inventor： Arif Sanli Ergun ,  Rupak Bardhan Roy ,  Ayhan Bozkurt

IPC: A61F9/007 ,  A61B8/08 ,  A61B8/00 ,  A61B8/14 ,  A61B8/10 ,  A61N7/02

CPC classification number: A61F9/00745 ,  A61B8/10 ,  A61B8/14 ,  A61B8/4281 ,  A61B8/4455 ,  A61B8/4494 ,  A61B8/5207 ,  A61F9/0079 ,  A61N7/02 ,  A61N2007/0052 ,  A61N2007/0078

Abstract: A device for thermal keratoplasty, the device comprising a plurality of ultrasonic transducers for emitting ultrasound waves, wherein the ultrasound waves of at least one of the transducers is focused on a corresponding area of the cornea in order to heat these area and cause collagen shrinkage and at least one of the transducers is capable of receiving ultrasound waves for ocular imaging.

Abstract translation: 一种用于热角膜移植术的装置，该装置包括用于发射超声波的多个超声换能器，其中至少一个换能器的超声波聚焦在角膜的相应区域上，以便加热这些区域并引起胶原收缩， 至少一个换能器能够接收用于眼部成像的超声波。

公开(公告)号：US20160007960A1

公开(公告)日：2016-01-14

申请号：US14771183

申请日：2013-02-28

Applicant: ALPINION MEDICAL SYSTEMS CO., LTD.

Inventor： Keonho SON ,  Kookjin KANG ,  Daeseung KIM ,  Myungdeok KIM ,  Sukhwan JUN

IPC: A61B8/00 ,  A61B8/08 ,  A61B8/14 ,  A61N7/02

CPC classification number: A61B8/4483 ,  A61B8/085 ,  A61B8/0883 ,  A61B8/12 ,  A61B8/14 ,  A61B8/445 ,  A61B8/4488 ,  A61B8/481 ,  A61B8/5207 ,  A61B2090/378 ,  A61N7/02 ,  A61N2007/0052 ,  A61N2007/0078 ,  A61N2007/0095 ,  G01N29/0654 ,  G01N29/262 ,  G01N2291/02475 ,  G01S7/5202 ,  G01S7/52063

Abstract: A method and an ultrasound medical apparatus for confirming a focal point of a high-intensity focused ultrasound are disclosed. A method of confirming a focal point, for pre-targeting a location of a high-intensity ultrasound by synchronizing the high-intensity ultrasound and an imaging ultrasound and using a reflected signal of the synchronized imaging ultrasound and high-intensity ultrasound from a focal point to which the ultrasounds are transmitted, and an ultrasound medical apparatus for implementing the method are provided.

Abstract translation: 公开了一种用于确认高强度聚焦超声的焦点的方法和超声波医疗装置。 一种确定焦点的方法，用于通过使高强度超声和成像超声同步并使用来自焦点的同步成像超声和高强度超声波的反射信号来预定位于高强度超声的位置 提供了超声波的发送，并且提供了用于实现该方法的超声波医疗装置。

公开(公告)号：US09204859B2

公开(公告)日：2015-12-08

申请号：US13092811

申请日：2011-04-22

Applicant: Michael Bailey ,  John Kucewicz ,  Wei Lu ,  Oleg Sapozhnikov ,  Paul Illian ,  Anup Shah ,  Barbrina Dunmire ,  Neil Owen ,  Bryan Cunitz ,  Peter Kaczkowski ,  Marla Paun

Inventor： Michael Bailey ,  John Kucewicz ,  Wei Lu ,  Oleg Sapozhnikov ,  Paul Illian ,  Anup Shah ,  Barbrina Dunmire ,  Neil Owen ,  Bryan Cunitz ,  Peter Kaczkowski ,  Marla Paun

IPC: A61B5/055 ,  A61B8/08 ,  A61B17/225 ,  A61B17/22 ,  A61B19/00 ,  G01S7/52 ,  G01S15/89 ,  A61B5/00

CPC classification number: A61B17/225 ,  A61B5/055 ,  A61B5/7232 ,  A61B6/03 ,  A61B6/485 ,  A61B8/085 ,  A61B8/488 ,  A61B17/2256 ,  A61B2017/22005 ,  A61B2090/378 ,  A61N7/00 ,  A61N2007/0004 ,  A61N2007/0052 ,  A61N2007/0082 ,  G01S7/52071 ,  G01S15/899

Abstract: Described herein are methods and apparatus for detecting stones by ultrasound, in which the ultrasound reflections from a stone are preferentially selected and accentuated relative to the ultrasound reflections from blood or tissue. Also described herein are methods and apparatus for applying pushing ultrasound to in vivo stones or other objects, to facilitate the removal of such in vivo objects.

Abstract translation: 这里描述了用于通过超声检测石块的方法和装置，其中相对于来自血液或组织的超声波反射优先选择和加强来自石头的超声反射。 本文还描述了将推进超声应用于体内石块或其它物体的方法和装置，以便于去除这样的体内物体。

公开(公告)号：US20150343243A1

公开(公告)日：2015-12-03

申请号：US14826061

申请日：2015-08-13

Applicant: Guided Therapy Systems, LLC

Inventor： Michael H. Slayton ,  Peter G. Barthe

IPC: A61N7/02 ,  A61B8/00 ,  A61B8/08 ,  A61B18/04 ,  A61B18/18

CPC classification number: A61N7/02 ,  A61B8/0825 ,  A61B8/14 ,  A61B8/4281 ,  A61B8/429 ,  A61B8/4483 ,  A61B8/461 ,  A61B8/483 ,  A61B18/04 ,  A61B18/18 ,  A61B2018/00333 ,  A61B2018/00577 ,  A61B2018/00642 ,  A61B2018/00791 ,  A61B2018/00904 ,  A61B2018/00994 ,  A61N2007/0052 ,  G01S7/52046 ,  G01S15/8909

Abstract: Methods and systems for noninvasive mastopexy through deep tissue tightening with ultrasound are provided. An exemplary method and system comprise a therapeutic ultrasound system configured for providing ultrasound treatment to a deep tissue region, such as a region comprising muscular fascia and ligaments. In accordance with various exemplary embodiments, a therapeutic ultrasound system can be configured to achieve depth from 1 mm to 4 cm with a conformal selective deposition of ultrasound energy without damaging an intervening tissue in the range of frequencies from 1 to 15 MHz. In addition, a therapeutic ultrasound can also be configured in combination with ultrasound imaging or imaging/monitoring capabilities, either separately configured with imaging, therapy and monitoring systems or any level of integration thereof.

公开(公告)号：US20150258352A1

公开(公告)日：2015-09-17

申请号：US14656633

申请日：2015-03-12

Applicant: Kuang-Wei LIN ,  Charles A. CAIN

Inventor： Kuang-Wei LIN ,  Charles A. CAIN

IPC: A61N7/00 ,  A61B17/22

CPC classification number: A61B17/22004 ,  A61B2017/22008 ,  A61N7/02 ,  A61N7/022 ,  A61N2007/0039 ,  A61N2007/0052 ,  A61N2007/0073 ,  A61N2007/0078

Abstract: Methods and devices for producing cavitation in tissue are provided. In one embodiment, a low-frequency ultrasound pulse is transmitted into tissue, a high-frequency ultrasound pulse is transmitted into tissue, and a composite waveform is formed in the tissue that has a peak negative pressure value that exceeds an intrinsic threshold for cavitation in the tissue. In some embodiments, the peak negative pressures of the individual ultrasound pulses do not exceed the intrinsic threshold for cavitation. In another embodiment, a plurality of ultrasound pulses at various resonant frequencies are transmitted into tissue, and the time delays between these transmissions are adjusted to allow the ultrasound pulses to align temporally and form a monopolar pulse having a compound peak negative pressure that exceeds an intrinsic threshold for cavitation in the tissue. Systems for performing Histotripsy therapy are also discussed.

Abstract translation: 提供了用于在组织中产生空化的方法和装置。 在一个实施例中，将低频超声脉冲传输到组织中，将高频超声脉冲传输到组织中，并且在组织中形成复合波形，该组合具有超过空化的固有阈值的峰值负压值 组织。 在一些实施例中，各个超声脉冲的峰值负压不超过空化的固有阈值。 在另一个实施例中，将多个谐振频率的多个超声脉冲传输到组织中，并且调整这些传输之间的时间延迟以允许超声波脉冲在时间上对准并形成具有超过内在的复合峰值负压的单极脉冲 组织中空化的阈值。 还讨论了用于进行组织切除术治疗的系统。

公开(公告)号：US09095695B2

公开(公告)日：2015-08-04

申请号：US11877348

申请日：2007-10-23

Applicant: Russell J. Fedewa ,  Toyoaki Uchida ,  Narendra T. Sanghvi ,  Roy F. Carlson

Inventor： Russell J. Fedewa ,  Toyoaki Uchida ,  Narendra T. Sanghvi ,  Roy F. Carlson

IPC: A61B18/04 ,  A61N7/02 ,  A61B19/00

CPC classification number: A61N7/00 ,  A61B34/10 ,  A61B2090/378 ,  A61N7/02 ,  A61N2007/0052 ,  A61N2007/0082

Abstract: A method and apparatus is disclosed for determining the success of a proposed HIFU Treatment, of an ongoing HIFU Treatment, and/or of a completed HIFU Treatment. An energy density of a given HIFU Treatment may be used as a comparison factor between the given HIFU Treatment and other HIFU Treatments and as a predictor of the success of the given HIFU Treatment. One exemplary energy density is the amount of energy deposited in the treatment region divided by the volume of the treatment region. Another exemplary energy density is the amount of energy deposited in the treatment region divided by the pre-treatment mass of the treatment region. A method and apparatus is disclosed to detect the presence of focal hyperechoic features and non-focal hyperechoic features. A method and apparatus is disclosed to detect the presence of an acoustic obstruction.

Abstract translation: 公开了一种用于确定所提出的HIFU治疗，正在进行的HIFU治疗和/或完成的HIFU治疗的成功的方法和装置。 给定HIFU治疗的能量密度可用作给定HIFU治疗与其他HIFU治疗之间的比较因子，并且作为给定HIFU治疗成功的预测因子。 一个示例性能量密度是在处理区域中沉积的能量的量除以处理区域的体积。 另一个示例性能量密度是处理区域中所沉积的能量除以处理区域的预处理质量。 公开了一种检测局灶性高回声特征和非局灶性高回声特征的存在的方法和装置。 公开了一种检测声阻塞的存在的方法和装置。

公开(公告)号：US09078594B2

公开(公告)日：2015-07-14

申请号：US13639109

申请日：2011-04-05

Applicant: Kenichi Kawabata ,  Rei Asami

Inventor： Kenichi Kawabata ,  Rei Asami

IPC: A61B8/00 ,  A61B8/08 ,  A61N7/02 ,  A61B8/13 ,  A61B17/00 ,  A61B19/00 ,  A61N7/00

CPC classification number: A61B8/08 ,  A61B8/13 ,  A61B8/481 ,  A61B2017/00106 ,  A61B2090/378 ,  A61B2503/40 ,  A61N7/02 ,  A61N2007/0039 ,  A61N2007/0052 ,  A61N2007/0065 ,  A61N2007/027

Abstract: Provided is an ultrasound diagnostic and treatment device for tumors which is used in combination with a phase-shift ultrasound contrast agent. By using a phase-shift ultrasound contrast agent, irradiating phase-shift ultrasonic waves from a phase-shift ultrasonic wave transmitter (18), irradiating ultrasonic waves for holding microbubbles from an ultrasonic wave transmitter (29) for holding microbubbles, and using a phase-shift detecting ultrasonic wave transceiver (19) to observe the phase shift, the ultrasound diagnostic and treatment device generates and holds the microbubbles in advance on the entire site (16) requiring treatment, and irradiates ultrasonic waves for treatment having a moderate intensity of 1 kW/cm2 or lower on the entire site (16) requiring treatment with the microbubbles as the target from a ultrasonic wave transmitter (20) for treatment.

Abstract translation: 提供了一种与移相超声对比剂组合使用的用于肿瘤的超声诊断和治疗装置。 通过使用移相超声造影剂，从相移超声波发射器（18）照射相移超声波，从用于保持微泡的超声波发射器（29）照射用于保持微泡的超声波，并使用相位 检测超声波收发器（19）观察相位偏移，超声诊断和治疗装置预先在需要治疗的整个部位（16）上产生并保持微泡，并照射超声波治疗中等强度1 需要以微泡作为靶的处理的整个部位（16）的超声波发射器（20）进行处理。