公开(公告)号：US20110263967A1

公开(公告)日：2011-10-27

申请号：US13092811

申请日：2011-04-22

Applicant: Michael Bailey ,  John Kucewicz ,  Wei Lu ,  Oleg Sapozhnikov ,  Paul Illian ,  Anup Shah ,  Barbrina Dunmire ,  Neil Owen ,  Bryan Cunitz ,  Peter Kaczkowski ,  Marla Paun

Inventor： Michael Bailey ,  John Kucewicz ,  Wei Lu ,  Oleg Sapozhnikov ,  Paul Illian ,  Anup Shah ,  Barbrina Dunmire ,  Neil Owen ,  Bryan Cunitz ,  Peter Kaczkowski ,  Marla Paun

IPC: A61B5/055 ,  A61B8/00 ,  A61N7/00

CPC classification number: A61B17/225 ,  A61B5/055 ,  A61B5/7232 ,  A61B6/03 ,  A61B6/485 ,  A61B8/085 ,  A61B8/488 ,  A61B17/2256 ,  A61B2017/22005 ,  A61B2090/378 ,  A61N7/00 ,  A61N2007/0004 ,  A61N2007/0052 ,  A61N2007/0082 ,  G01S7/52071 ,  G01S15/899

Abstract: Described herein are methods and apparatus for detecting stones by ultrasound, in which the ultrasound reflections from a stone are preferentially selected and accentuated relative to the ultrasound reflections from blood or tissue. Also described herein are methods and apparatus for applying pushing ultrasound to in vivo stones or other objects, to facilitate the removal of such in vivo objects.

Abstract translation: 这里描述了用于通过超声检测石块的方法和装置，其中相对于来自血液或组织的超声波反射优先选择和加强来自石头的超声反射。 本文还描述了将推进超声应用于体内石块或其它物体的方法和装置，以便于去除这样的体内物体。

公开(公告)号：US09005126B2

公开(公告)日：2015-04-14

申请号：US12114703

申请日：2008-05-02

Applicant: Kirk Beach ,  John C. Kucewicz ,  Barbrina Dunmire

Inventor： Kirk Beach ,  John C. Kucewicz ,  Barbrina Dunmire

IPC: A61B8/00 ,  G06K9/00 ,  A61B8/08 ,  A61B5/0402

CPC classification number: A61B8/0808 ,  A61B5/0402 ,  A61B8/0816

Abstract: Tissue Pulsatility Imaging (TPI) is an ultrasonic technique developed to measure tissue displacement or strain in the brain due to blood flow over the cardiac and respiratory cycles. Such measurements can be used to facilitate the mapping of brain function as well as to monitor cerebral vasoreactivity. Significantly, because tissue scatters ultrasound to a greater extend than does blood, using ultrasound to measure tissue displacement or strain in the brain is easier to implement than using ultrasound to measure blood flow in the brain. Significantly, transcranial Doppler sonography (TCD) has been used to measure blood flow in the brain to map brain function and monitor cerebral vasoreactivity; however, TCD can only acquire data through the three acoustic windows in the skull, limiting the usefulness of TCD. TPI is not so limited.

Abstract translation: 组织脉搏成像（TPI）是一种超声技术，用于测量由于心脏和呼吸周期中的血流引起的脑部组织位移或应变。 这样的测量可以用于促进脑功能的映射以及监测脑血管反应性。 值得注意的是，由于组织比血液扩散超声波更大，使用超声测量大脑中的组织位移或应变比使用超声波测量大脑中的血流量更容易实现。 重要的是，经颅多普勒超声（TCD）已被用于测量脑中的血流量，以映射脑功能并监测脑血管反应性; 然而，TCD只能通过颅骨中的三个声窗口获得数据，限制了TCD的有用性。 TPI并不限于此。

公开(公告)号：US20080275340A1

公开(公告)日：2008-11-06

申请号：US12114703

申请日：2008-05-02

Applicant: Kirk Beach ,  John C. Kucewicz ,  Barbrina Dunmire

Inventor： Kirk Beach ,  John C. Kucewicz ,  Barbrina Dunmire

IPC: A61B8/00

CPC classification number: A61B8/0808 ,  A61B5/0402 ,  A61B8/0816

Abstract: Tissue Pulsatility Imaging (TPI) is an ultrasonic technique developed to measure tissue displacement or strain in the brain due to blood flow over the cardiac and respiratory cycles. Such measurements can be used to facilitate the mapping of brain function as well as to monitor cerebral vasoreactivity. Significantly, because tissue scatters ultrasound to a greater extend than does blood, using ultrasound to measure tissue displacement or strain in the brain is easier to implement than using ultrasound to measure blood flow in the brain. Significantly, transcranial Doppler sonography (TCD) has been used to measure blood flow in the brain to map brain function and monitor cerebral vasoreactivity; however, TCD can only acquire data through the three acoustic windows in the skull, limiting the usefulness of TCD. TPI is not so limited.

Abstract translation: 组织脉搏成像（TPI）是一种超声技术，用于测量由于心脏和呼吸周期中的血流引起的脑部组织位移或应变。 这样的测量可以用于促进脑功能的映射以及监测脑血管反应性。 值得注意的是，由于组织超声波比血液扩散更大，使用超声波测量脑组织位移或应变比使用超声波测量大脑中的血流量更容易实现。 重要的是，经颅多普勒超声（TCD）已被用于测量脑中的血流量，以映射脑功能并监测脑血管反应性; 然而，TCD只能通过颅骨中的三个声窗口获得数据，限制了TCD的有用性。 TPI并不限于此。

公开(公告)号：US20190314045A1

公开(公告)日：2019-10-17

申请号：US16383386

申请日：2019-04-12

Applicant: Bryan Cunitz ,  Kennedy Hall ,  Mathew Sorenson ,  Michael R. Bailey ,  Adam D. Maxwell ,  Barbrina Dunmire ,  Oren Levy ,  Doug Corl ,  Paul Fasolo

Inventor： Bryan Cunitz ,  Kennedy Hall ,  Mathew Sorenson ,  Michael R. Bailey ,  Adam D. Maxwell ,  Barbrina Dunmire ,  Oren Levy ,  Doug Corl ,  Paul Fasolo

IPC: A61B17/22 ,  A61B8/08 ,  A61B5/00 ,  A61B8/00

Abstract: Targeting methods and devices for non-invasive therapy delivery are disclosed. In one embodiment, a method for targeting an object in a body using ultrasound includes: producing a therapy ultrasound waveform configured to fragment or comminute the object in the body using a therapy transducer of an ultrasound probe; and acquiring a sound waveform by a receiver. The sound waveform is at least in part caused by interactions of the therapy ultrasound with the object. The method also includes generating an indication of a targeting accuracy based on the acquired sound waveform.

公开(公告)号：US09204859B2

公开(公告)日：2015-12-08

申请号：US13092811

申请日：2011-04-22

Applicant: Michael Bailey ,  John Kucewicz ,  Wei Lu ,  Oleg Sapozhnikov ,  Paul Illian ,  Anup Shah ,  Barbrina Dunmire ,  Neil Owen ,  Bryan Cunitz ,  Peter Kaczkowski ,  Marla Paun

Inventor： Michael Bailey ,  John Kucewicz ,  Wei Lu ,  Oleg Sapozhnikov ,  Paul Illian ,  Anup Shah ,  Barbrina Dunmire ,  Neil Owen ,  Bryan Cunitz ,  Peter Kaczkowski ,  Marla Paun

IPC: A61B5/055 ,  A61B8/08 ,  A61B17/225 ,  A61B17/22 ,  A61B19/00 ,  G01S7/52 ,  G01S15/89 ,  A61B5/00

CPC classification number: A61B17/225 ,  A61B5/055 ,  A61B5/7232 ,  A61B6/03 ,  A61B6/485 ,  A61B8/085 ,  A61B8/488 ,  A61B17/2256 ,  A61B2017/22005 ,  A61B2090/378 ,  A61N7/00 ,  A61N2007/0004 ,  A61N2007/0052 ,  A61N2007/0082 ,  G01S7/52071 ,  G01S15/899

Abstract: Described herein are methods and apparatus for detecting stones by ultrasound, in which the ultrasound reflections from a stone are preferentially selected and accentuated relative to the ultrasound reflections from blood or tissue. Also described herein are methods and apparatus for applying pushing ultrasound to in vivo stones or other objects, to facilitate the removal of such in vivo objects.

Abstract translation: 这里描述了用于通过超声检测石块的方法和装置，其中相对于来自血液或组织的超声波反射优先选择和加强来自石头的超声反射。 本文还描述了将推进超声应用于体内石块或其它物体的方法和装置，以便于去除这样的体内物体。