公开(公告)号：US10591417B2

公开(公告)日：2020-03-17

申请号：US16448670

申请日：2019-06-21

Applicant: Verily Life Sciences LLC

Inventor： Charles Santori ,  Supriyo Sinha ,  Cheng-Hsun Wu ,  James Higbie ,  Seung Ah Lee

IPC: G01J3/18 ,  G01N21/64 ,  G01J3/44 ,  G02B21/00 ,  G02B21/16 ,  G01J3/10 ,  G01J3/28 ,  G01J3/433 ,  G01J3/02 ,  A61B5/00 ,  G01J3/32 ,  G01J3/12

Abstract: Systems and methods for hyperspectral imaging are described. In one implementation, a hyperspectral imaging system includes a sample holder configured to hold a sample, an illumination system, and a detection system. The illumination system includes a light source configured to emit excitation light having one or more wavelengths and a diffractive element. The illumination system is configured to structure the excitation light into a predetermined two-dimensional pattern at a conjugate plane of a focal plane in the sample, spectrally disperse the structured excitation light in a first lateral direction, and illuminate the sample in an excitation pattern with the one or more wavelengths dispersed in the first lateral direction.

公开(公告)号：US10578597B2

公开(公告)日：2020-03-03

申请号：US16217534

申请日：2018-12-12

Applicant: Michele Hinnrichs

Inventor： Michele Hinnrichs

IPC: G01N33/00 ,  G01J3/18 ,  G02B5/18 ,  G01J3/02 ,  G01N21/3504 ,  G01J3/26 ,  G01J3/28 ,  G01J1/06

Abstract: A spectral radiation gas detector has at least one lenslet with a circular blazed grating for diffraction of radiation to a focal plane. A detector is located at the focal plane receiving radiation passing through the at least one lenslet for detection at a predetermined diffraction order. A plurality of order filters are associated with the at least one lenslet to pass radiation at wavelengths corresponding to the predetermined diffraction order, each filter blocking a selected set of higher orders. A controller is adapted to compare intensity at pixels in the detector associated with each of the plurality of order filters and further adapted to determine a change in intensity exceeding a threshold.

公开(公告)号：US10571442B2

公开(公告)日：2020-02-25

申请号：US15341104

申请日：2016-11-02

Applicant: Matthias Lenzner

Inventor： Matthias Lenzner

IPC: G01N33/00 ,  G01J3/453 ,  G01J3/00 ,  G01J3/45 ,  G01J3/18 ,  G01J3/12

Abstract: A technique and device to determine the spectrum of electromagnetic radiation in a certain range of wavelengths comprising: splitting said radiation into more than one beam; let these beams counter-propagate in a Sagnac-type ring interferometer; and imprinting a wavelength-dependent angular tilt onto the wavefront of each beam by at least one dispersive element which preferably is a transmission grating or grism; and re-combining the multiple beams on a detector that exhibits spatial resolution and can therefore resolve the fringes formed by interference; and perform the mathematical operations to determine the spectrum of said radiation from the obtained interferogram, wherein the dispersive element is mounted on a stage providing linear and/or rotational movement.

公开(公告)号：US20200049553A1

公开(公告)日：2020-02-13

申请号：US16441081

申请日：2019-06-14

Applicant: Shimadzu Corporation

Inventor： Hiroyuki MINATO

IPC: G01J3/02 ,  G01J3/18

Abstract: A spectroscopic detector includes a light source, a flow cell, a diffraction grating, a diffraction grating drive unit, an optical sensor and a diffraction grating position adjustment unit. The diffraction grating drive unit is configured to adjust a rotation position of the diffraction grating within a range that light of a specified wavelength region of plus side diffracted light and light of the specified wavelength region of minus side diffracted light among diffracted light caused by the diffraction grating is selectively guided to the flow cell. The diffraction grating position adjustment unit is configured to adjust the rotation position of the diffraction grating unit in order to selectively guide one of the light of the specified wavelength region of the plus side diffracted light and the light of the specified wavelength region of the minus side diffracted light among the diffracted light caused by the diffraction grating.

公开(公告)号：US20200018646A1

公开(公告)日：2020-01-16

申请号：US16582550

申请日：2019-09-25

Applicant: SAMSUNG ELECTRONICS CO., LTD. ,  IMEC VZW

Inventor： Seongho Cho ,  Tom Claes ,  Dongho Kim

IPC: G01J3/02 ,  G01J3/26 ,  G01J3/18 ,  G01J3/36 ,  A61B5/00 ,  G02B6/124 ,  G01N21/27 ,  G01N21/47 ,  A61B5/145 ,  A61B5/1455

Abstract: Provided are a dual coupler device configured to receive lights of different polarization components, a spectrometer including the dual coupler device, and a non-invasive biometric sensor including the spectrometer. The dual coupler device may include, for example, a first coupler layer configured to receive a light of a first polarization component among incident lights. and a second coupler layer configured to receive a light of a second polarization component among the incident lights, wherein a polarization direction of the light of the first polarization component is perpendicular to a polarization direction of the light of the second polarization component. The first coupler layer and the second coupler layer may be spaced apart from each other and extended along a direction in which the light propagates in the first coupler layer and the second coupler layer.

公开(公告)号：US10527552B2

公开(公告)日：2020-01-07

申请号：US15781991

申请日：2016-04-18

Applicant: Hewlett-Packard Development Company, L.P.

Inventor： Francesco Aieta ,  Anita Rogacs ,  Viktor Shkolnikov

IPC: G01N21/65 ,  G01J3/02 ,  G01J3/10 ,  G01J3/44 ,  G01J3/18

Abstract: In an example, an apparatus is described that includes a light source, a holographic optical element, a sampling apparatus, and a detector. The light source is configured to emit a beam of excitation light. The holographic optical element is arranged to convert the beam of excitation light into a plurality of beams of excitation light. The sampling apparatus is arranged to project the plurality of beams of excitation light onto a surface outside the apparatus as a two-dimensional pattern of projection points. The sampling apparatus is further arranged to collect scattered radiation emitted by the surface in response to the two-dimensional pattern of projection points. The detector detects a frequency shift in the scattered radiation.

公开(公告)号：US10508951B2

公开(公告)日：2019-12-17

申请号：US16068316

申请日：2017-01-06

Applicant: Nederlandse Organisatie voor toegepast-natuurwetenschappelijk onderzoek TNO

Inventor： Borgert Kruizinga ,  Hedser van Brug ,  Frerik van Beijnum

IPC: G01J3/02 ,  G01J3/28 ,  G01J3/18 ,  G01J3/12

Abstract: A monolithic spectrometer (10) for spectrally resolving light (L), comprises a body (2) of solid material having optical surfaces (3,4,5,6a-6c,8) configured to guide the light (L) along an optical path (E1,E2,E3,E4) inside the body (2). The optical surfaces of the body (2) comprise a segmented focusing surface (6a,6b) comprising first and second continuously functional optical shapes (Ca,Cb) to focus received parts of respective beams (La,Lb) onto respective focal position (fa,fb) in an imaging plane (P) outside the body (2). The second continuously functional optical shape (Cb) is separated from the first continuously functional optical shape (Ca) by an optical discontinuity (Dab) there between.

公开(公告)号：US10481074B2

公开(公告)日：2019-11-19

申请号：US16015807

申请日：2018-06-22

Applicant: Becton, Dickinson and Company

Inventor： Collin A. Rich

IPC: G01N15/14 ,  G16B5/00 ,  G16B45/00 ,  G16B99/00 ,  G01J3/18 ,  G01J3/36 ,  G01J3/02 ,  G01J3/28 ,  G06M11/02

Abstract: Systems in a flow cytometer having an interrogation zone and illumination impinging the interrogation zone include: a lens subsystem including a collimating element that collimates light from the interrogation zone, a light dispersion element that disperses collimated light into a light spectrum, and a focusing lens that focuses the light spectrum onto an array of adjacent detection points; a detector array, including semiconductor detector devices, that collectively detects a full spectral range of input light signals, in which each detector device detects a subset spectral range of the full spectral range of light signals; and a user interface that enables a user to create a set of virtual detector channels by grouping detectors in the detector array, such that each virtual detector channel corresponds to a detector group and has a virtual detector channel range including the sum of subset spectral ranges of the detectors in the corresponding detector group.

公开(公告)号：US20190339127A1

公开(公告)日：2019-11-07

申请号：US16437325

申请日：2019-06-11

Applicant: Oak Analytics

Inventor： Ruibo Wang ,  Pawel Adam Menzfeld

IPC: G01J3/10 ,  G01J3/44 ,  G01J3/36 ,  G01J3/28 ,  G01J3/06 ,  G01J3/02 ,  G01J3/18

Abstract: A compact spectrometer includes an excitation light source configured to generate excitation light and arranged to illuminate a spot on a sample. A dispersive element includes at least one movable component and spatially separates output light emanating from the sample in response to the excitation light into a plurality of different wavelength bands. A moveable component of the dispersive element causes the plurality of different wavelength bands of the output light to be scanned across a detector. The detector includes at least one light sensor that senses the wavelength bands of the output light and generates an output electrical signal in response to the sensed output light.

公开(公告)号：US10444145B2

公开(公告)日：2019-10-15

申请号：US15571197

申请日：2016-05-03

Applicant: BAE Systems Information and Electronic Systems Integration Inc.

Inventor： Kevin R. Maschhoff ,  Gerard M. Perron ,  John J. Polizotti

IPC: G01J3/02 ,  G01N21/41 ,  G01N21/3518 ,  G01W1/04 ,  G01J3/18 ,  G01J3/28 ,  G01J5/00 ,  G01J5/20 ,  H01L31/107 ,  G01J5/04 ,  G01J5/02 ,  G01J5/06 ,  G01N21/3554 ,  G01N21/17 ,  G01N21/3504

Abstract: A mid-wave infrared system provides high spatial and temporal resolution measurements of atmospheric temperatures and moisture fields using a constellation of low earth orbit satellites. The disclosed system is smaller, lighter, less complex, and requires less energy than existing systems, due to implementation of an infrared avalanche photodiode array detector that provides enhanced sensitivity with reduced cooling requirements, and an Offner spectrometer having a novel a refractive element inserted near the grating that reduces the size and power requirements of the spectrometer. Embodiments of the disclosed method include deploying a constellation of devices for cooperative infrared sensing of atmospheric phenomena at similar rates, lower cost, and much higher resolution compared to geosynchronous approaches. Some embodiments further include combined analysis of measurements obtained by the disclosed devices with complementary measurements made by other low-earth and high-earth orbital and/or ground-based devices.