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公开(公告)号：US20220082504A1
公开(公告)日：2022-03-17
申请号：US17415203
申请日：2019-06-04
发明人： Fausto D'Apuzzo , Steven Barcelo , Anita Rogacs
摘要： Systems and methods for generating calibration curve for a sensor are provided. An example method includes printing at least two spots of an analyte on the sensor, wherein each of the spots includes a different number of overprinted droplets ejected from a single printhead.
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公开(公告)号：US11199499B2
公开(公告)日：2021-12-14
申请号：US16076345
申请日：2017-07-20
发明人： Milo Overbay , Anita Rogacs , Devin A. Mourey
摘要： A surface enhanced luminescence analyte interrogation stage may include a substrate and an array of pillars projecting from the substrate. Each of the pillars may include a polymeric post formed from a first material and a cap on the polymeric post. The cap has a plasmonic surface and is formed from a second material different than the first. A sacrificial coating covers the cap of each of the pillars.
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公开(公告)号：US20190154587A1
公开(公告)日：2019-05-23
申请号：US16098067
申请日：2016-07-20
发明人： Ning Ge , Robert G. Walmsley , Helen A. Holder , Steven J. Simske , Anita Rogacs , Viktor Shkolnikov
IPC分类号： G01N21/65
CPC分类号： G01N21/658 , B82Y15/00
摘要： A gas conduit directs a flow of gas from a gas flow source. A surface enhanced luminescence (SEL) stage is within the conduit and includes a substrate and nano fingers projecting from the substrate. A heater heats the nano fingers to a temperature so as to soften the nano fingers such that the nano fingers collapse towards each other to capture molecules entrained in the gas therebetween.
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公开(公告)号：US20190145897A1
公开(公告)日：2019-05-16
申请号：US16097962
申请日：2016-07-22
发明人： Ning Ge , Helen A. Holder , Steven J. Simske , Anita Rogacs , Viktor Shkolnikov
摘要： An activatable SEL sensor stage may include a substrate, cation metal-based material masses supported by the substrate and isolated from one another and dielectric capping layer over the cation metal-based material masses to inhibit oxidation of the cation metal-based material masses.
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公开(公告)号：US11441960B2
公开(公告)日：2022-09-13
申请号：US16074349
申请日：2016-04-20
发明人： Ning Ge , Alexander Govyadinov , Anita Rogacs , Viktor Shkolnikov
摘要： A microfluidic pressure sensor may include a reference chamber, a sensed volume, a microfluidic channel connecting an interior of the reference chamber to an interior of the sensed volume, a volume of liquid contained and movable within the microfluidic channel while occluding the microfluidic channel and a sensor to output signals indicating positioning of the volume of liquid along the microfluidic channel. Positioning of the volume of liquid along microfluidic channel indicates a pressure of the sensed volume.
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公开(公告)号：US11280739B2
公开(公告)日：2022-03-22
申请号：US16077334
申请日：2017-07-17
发明人： Raghuvir N. Sengupta , Anita Rogacs
摘要： A surface enhanced luminescence system may include a laser and a controller to output control signals causing the laser to irradiate the pre-analyte exposed plasmonic surface while maintaining a profile of the pre-analyte exposed plasmonic surface.
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公开(公告)号：US11169091B2
公开(公告)日：2021-11-09
申请号：US16082399
申请日：2017-07-20
IPC分类号： G01N1/10 , G01N21/552 , G01N21/64 , G01N21/65
摘要： A surfaced enhanced luminescence analyte interrogation stage shipping and storage package may include a sealed chamber, a liquid contained within the sealed chamber and nano pillars within the sealed chamber and submersed within the liquid. The nano pillars comprise polymer posts and metallic caps forming tips of the nano pillars.
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公开(公告)号：US11131608B2
公开(公告)日：2021-09-28
申请号：US15756965
申请日：2015-10-23
发明人： Viktor Shkolnikov , Anita Rogacs
摘要： A target analyte is extracted out of a sample fluid in a sample fluid passage by diffusing the target analyte through a supported liquid membrane to a product fluid passage. Extraction of the target analyte is accelerated by applying an electric field across and perpendicular to the supported liquid membrane with electrodes. Passage of selected ions across an exchange membrane extending between one of the electrodes and the supported liquid membrane is inhibited.
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公开(公告)号：US20210252499A1
公开(公告)日：2021-08-19
申请号：US17054675
申请日：2018-10-11
IPC分类号： B01L3/02
摘要： In one example, an apparatus includes a surface-enhanced substrate having a microdot deposited onto a surface thereon via a microfluidic ejector. The microdot includes a predetermined concentration of an analyte.
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公开(公告)号：US20210163866A1
公开(公告)日：2021-06-03
申请号：US17047336
申请日：2018-08-21
摘要： An example of an apparatus includes an inlet to receive a plurality of cells suspended in a solution. The apparatus also includes a microfluidic channel to transport the plurality of cells suspended in the solution. In addition, the apparatus includes a trap disposed along the microfluidic channel, wherein the trap is to isolate the plurality of cells suspended in the solution. Also, the apparatus includes a buffer supply to dispense a buffer to wash the plurality of cells and to remove the solution from the microfluidic channel. The apparatus further includes a sensor to measure a characteristic of the plurality of cells after isolated from the solution.
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