公开(公告)号：US20080153172A1

公开(公告)日：2008-06-26

申请号：US11587297

申请日：2005-04-14

Applicant: Marie Asberg ,  Ake Nygren ,  Rolf Ekman

Inventor： Marie Asberg ,  Ake Nygren ,  Rolf Ekman

IPC: G01N33/68

CPC classification number: G01N33/74 ,  G01N33/6863 ,  G01N2333/475 ,  G01N2333/485 ,  G01N2333/52 ,  G01N2333/54 ,  G01N2333/59

Abstract: A method of diagnosis of chronic stress in a patient, comprising: (a) determining the level of each of one or more analytes in the patient, wherein the one or more analytes are selected from VEGF, IL-8, MCP1, EGF and TSH; and (b) establishing the significance of the or each level.

Abstract translation: 一种诊断患者慢性应激的方法，包括：（a）确定患者中一种或多种分析物中的每一种的水平，其中所述一种或多种分析物选自VEGF，IL-8，MCP1，EGF和TSH ; 和（b）确定每个级别的重要性。

公开(公告)号：US20070281895A1

公开(公告)日：2007-12-06

申请号：US10595747

申请日：2004-11-09

Applicant: Martin Crockard ,  Janice Bailie ,  John Lamont ,  Stephen Fitzgerald

Inventor： Martin Crockard ,  Janice Bailie ,  John Lamont ,  Stephen Fitzgerald

IPC: C12Q1/68 ,  A61K31/7105 ,  C07K14/00 ,  C07K16/30 ,  C07K7/00

CPC classification number: C12Q1/6886 ,  C12Q2600/158

Abstract: A diagnostic method is disclosed which can be used to predict the risk of cancer in particular breast cancer. The method comprises: (i) isolating a biological sample from a patient; and (ii) detecting the presence or expression of the gene comprised within the sequence identified herein as SEQ ID No. (1), wherein the presence or expression of the gene indicates the presence of or the risk of cancer.

Abstract translation: 公开了可以用于预测癌症特别是乳腺癌的风险的诊断方法。 该方法包括：（i）从患者分离生物样品; （ii）检测本文鉴定的序列中包含的基因的存在或表达，如SEQ ID No.（1），其中基因的存在或表达表示癌症的存在或癌症的风险。

公开(公告)号：US07270788B2

公开(公告)日：2007-09-18

申请号：US10643926

申请日：2003-08-20

Applicant: James Rudolph Meyer ,  Ahti Kalevi Kansanaho ,  Stephen Peter Fitzgerald ,  Ivan Robert McConnell ,  John Victor Lamont ,  Bailin Cao

Inventor： James Rudolph Meyer ,  Ahti Kalevi Kansanaho ,  Stephen Peter Fitzgerald ,  Ivan Robert McConnell ,  John Victor Lamont ,  Bailin Cao

IPC: B01L3/02

CPC classification number: G01N35/028 ,  G01N35/00029 ,  G01N35/0099 ,  G01N2035/00158 ,  G01N2035/00326 ,  G01N2035/0425 ,  Y10T436/113332

Abstract: An assay device processing instrument comprises a plurality of processing modules. A transport system transports an assay device to each processing module, the transport system being adapted to transfer the assay device from the transport system to the module to enable the transport system to transport another assay device while the first is processed by the processing module. A control system controls operation of the transport system such that each assay device is transferred between the modules in a predetermined sequence, and such that a number of assay devices can be processed in different modules simultaneously.

Abstract translation: 测定装置处理装置包括多个处理模块。 运输系统将测定装置运送到每个处理模块，所述运输系统适于将测定装置从运输系统传送到模块，以使得运输系统能够在第一个由处理模块处理的同时运送另一个测定装置。 控制系统控制运输系统的操作，使得每个测定装置以预定顺序在模块之间转移，并且使得可以同时在不同模块中处理多个测定装置。

公开(公告)号：US07026134B2

公开(公告)日：2006-04-11

申请号：US10323850

申请日：2002-12-20

Applicant: John Victor Lamont ,  Robert Ivan McConnell ,  Stephen Peter Fitzgerald ,  El Ouard Benchikh ,  Andrew Philip Lowry

Inventor： John Victor Lamont ,  Robert Ivan McConnell ,  Stephen Peter Fitzgerald ,  El Ouard Benchikh ,  Andrew Philip Lowry

IPC: G01N33/535 ,  C07K16/44 ,  C12P21/08 ,  C07D471/08

CPC classification number: G01N33/9486 ,  C07D489/02

Abstract: Novel haptens, which can be conjugated to form immunogens, are of formula I, II or III wherein R is a divalent alkyl, cycloalkyl or aryl group having 1 to 10 carbon atoms, and X is a functional group.

公开(公告)号：US20030157565A1

公开(公告)日：2003-08-21

申请号：US10323850

申请日：2002-12-20

Applicant: RANDOX LABORATORIES LTD.

Inventor： John Victor Lamont ,  Robert Ivan McConnell ,  Stephen Peter Fitzgerald ,  El Ouard Benchikh ,  Andrew Philip Lowry

IPC: G01N033/53 ,  G01N033/537 ,  G01N033/543 ,  C07K016/46 ,  C07K014/00 ,  C07D489/02

CPC classification number: G01N33/9486 ,  C07D489/02

Abstract: Novel haptens, which can be conjugated to form immunogens, are of formula I, II or III 1 wherein R is a divalent alkyl, cycloalkyl or aryl group having 1 to 10 carbon atoms, and X is a functional group.

Abstract translation: 可以结合形成免疫原的新型半抗原具有式I，II或III，其中R是具有1至10个碳原子的二价烷基，环烷基或芳基，X是官能团。

公开(公告)号：US20030109051A1

公开(公告)日：2003-06-12

申请号：US10269884

申请日：2002-10-15

Applicant: RANDOX LABORATORIES LTD

Inventor： Stephen Peter Fitzgerald ,  Lynne Hamilton ,  Paul Graham Winyard

IPC: G01N033/50

CPC classification number: G01N33/84

Abstract: A spin-trapping assay for nitric oxide, in a biological system such as whole blood, uses as the spin trap a lipid-soluble nitrobenzene compound such as 2,6-dimethylnitrosobenzene.

Abstract translation: 在诸如全血的生物系统中，一氧化氮的自旋捕获测定法用作可溶性硝基苯化合物如2,6-二甲基亚硝基苯的自旋阱。

公开(公告)号：US20030008385A1

公开(公告)日：2003-01-09

申请号：US10188796

申请日：2002-07-05

Applicant: RANDOX LABORATORIES LTD

Inventor： Mark Tweedie ,  John Victor Lamont ,  Robert Ivan McConnell ,  Stephen Peter Fitzgerald

IPC: C12M001/34 ,  B05D003/00 ,  B41J029/38

CPC classification number: G01N35/00603 ,  B01J19/0046 ,  B01J2219/00351 ,  B01J2219/00527 ,  B01J2219/00529 ,  B01J2219/0054 ,  B01J2219/00545 ,  B01J2219/00547 ,  B01J2219/00585 ,  B01J2219/0059 ,  B01J2219/00596 ,  B01J2219/00605 ,  B01J2219/00659 ,  B01J2219/00677 ,  B01J2219/00689 ,  B01J2219/00691 ,  B01J2219/00693 ,  B01L3/0268 ,  B82Y30/00 ,  C40B60/14 ,  C40B70/00 ,  G01N35/10 ,  G01N2035/1034

Abstract: A biochip deposition system and method. The system comprises a deposit mechanism for depositing organic material in spots on a substrate; and a viewing system for detecting the spots on the substrate during a deposit operation and before the spots have dried, for determining if the spots have been correctly deposited, and if not, for generating a suitable output signal. The viewing system includes an illumination device for illuminating deposited spots at a relatively low angle relative to the substrate.

Abstract translation: 一种生物芯片沉积系统及方法。 该系统包括用于在基板上的点沉积有机材料的沉积机构; 以及观察系统，用于在沉积操作期间和斑点干燥之前检测基板上的斑点，以确定斑点是否已被正确沉积，如果不是，则用于产生合适的输出信号。 观察系统包括用于以相对于衬底相对低的角度照射沉积点的照明装置。