公开(公告)号：US20090287078A1

公开(公告)日：2009-11-19

申请号：US12214947

申请日：2008-06-24

申请人： Fred H. Burbank ,  Michael L. Jones ,  Frank Louw ,  Paul Lubock

发明人： Fred H. Burbank ,  Michael L. Jones ,  Frank Louw ,  Paul Lubock

IPC分类号： A61B6/00 ,  A61M5/00

CPC分类号： A61B90/39 ,  A61B2090/3908 ,  A61B2090/3925 ,  A61B2090/3933 ,  A61B2090/3987 ,  A61K49/226

摘要： A solution for forming a marker or filler mass for an intracorporeal site. The solution contains a polar, water soluble non-aqueous solvent such as dimethyl sulfoxide and a bioabsorbable, essentially water insoluble polymer such as polylactic acid, or copolymers of lactic acid and glycolic acid. The solution may be delivered to the biopsy site by a suitable syringe and delivery tube. The delivery tube is preferably provided with a releasable radiopaque element on the distal tip which can be released within the polymeric marker mass formed in the biopsy cavity.

摘要翻译： 用于形成体内部位的标记物或填充剂块的溶液。 该溶液含有极性的水溶性非水溶剂如二甲基亚砜和生物可吸收的，基本上不溶于水的聚合物如聚乳酸，或乳酸和乙醇酸的共聚物。 溶液可以通过合适的注射器和输送管递送到活检部位。 输送管优选地设置在远端上的可释放的不透射线元件，其可以在形成于活检腔内的聚合物标记块内释放。

公开(公告)号：US20090204021A1

公开(公告)日：2009-08-13

申请号：US12322749

申请日：2009-02-06

申请人： Martin V. Shabaz ,  Richard L. Quick ,  Frank R. Louw ,  Paul Lubock ,  Jason Safabash

发明人： Martin V. Shabaz ,  Richard L. Quick ,  Frank R. Louw ,  Paul Lubock ,  Jason Safabash

IPC分类号： A61B10/02 ,  A61B17/32

CPC分类号： A61B10/0275 ,  A61B10/0283 ,  A61B17/32002 ,  A61B17/32053 ,  A61B17/3417 ,  A61B2010/0208 ,  A61B2010/0225 ,  A61B2017/00473 ,  A61B2017/3405

摘要： A device to access a desired tissue site within a patient's body and separate a tissue specimen from the tissue site. The device includes a probe member having a tissue penetrating distal tip having a plurality of concaved surfaces which form curved cutting edges at the intersection of adjacent concave surfaces. The probe member has an inner lumen which when subjected to a vacuum, secures tissue for the specimen to the surface of a distal tubular section of the probe which may be off-set from a central longitudinal axis. A circular tissue-cutting blade is configured to move longitudinally to sever a tissue specimen from tissue secured to the surface of the distal tubular section by the application of a vacuum to the inner lumen of the probe.

摘要翻译： 一种用于访问患者体内所需组织部位并从组织部位分离组织标本的装置。 该装置包括具有组织穿透远侧末端的探针构件，该组织穿透远侧末端具有多个凹面，其在相邻凹面的交叉处形成弯曲的切割边缘。 探针构件具有内腔，当经受真空时，将内窥镜的组织固定在探针的远侧管状部分的表面上，该表面可以从中心纵向轴线偏离。 圆形组织切割刀片构造成纵向移动以通过向探针的内腔施加真空而将组织标本从组织固定到远端管状部分的表面。

公开(公告)号：US20090198095A1

公开(公告)日：2009-08-06

申请号：US12321286

申请日：2009-01-20

申请人： George M. Acosta ,  Paul Lubock

发明人： George M. Acosta ,  Paul Lubock

IPC分类号： A61M36/04

CPC分类号： A61N5/1015 ,  A61F7/123 ,  A61M25/10 ,  A61M25/1034 ,  A61M25/1036 ,  A61M2025/0036 ,  A61M2025/004 ,  A61N1/403 ,  A61N2005/1018

摘要： The disclosure describes a device for asymmetrical irradiation of a body cavity or site, such as after removal of tissue, e.g. biopsy or lumpectomy. The device includes an elongated tubular shaft having an inner lumen and a tubular wall with a plurality of lumens extending within the wall which are configured for receiving a radiation source. The distal portion of the tubular shaft is cut into a plurality of longitudinally separated wall segments with a lumen extending within at least one of the wall segments. A support member is positioned within the separated wall segments to support and position the wall segments in a desired configuration for brachytherapy. An expandable member such as an inflatable balloon is mounted on the distal shaft portion about the separated wall segments wall which when inflated secures the distal shaft portion within a desired intracorporeal site for brachytherapy treatment.

摘要翻译： 本公开描述了用于体腔或部位的不对称照射的装置，例如在去除组织之后，例如， 活检或肿瘤切除术。 该装置包括细长的管状轴，其具有内腔和具有在壁内延伸的多个内腔的管状壁，其构造成用于接收辐射源。 管状轴的远端部分被切割成多个纵向分离的壁段，其中内腔在至少一个壁段内延伸。 支撑构件被定位在分离的壁段内以支撑和定位所需的构造的壁段用于近距离放射治疗。 诸如可膨胀气囊的可膨胀构件围绕分离的壁段壁安装在远侧轴部分上，当被充气时将远端轴部分固定在期望的体内位置以进行近距离放射治疗。

公开(公告)号：US07565191B2

公开(公告)日：2009-07-21

申请号：US11238201

申请日：2005-09-29

申请人： Fred H. Burbank ,  Paul Lubock ,  Michael L. Jones ,  Richard L. Quick ,  Frank Louw ,  Stephen A. De Santis

发明人： Fred H. Burbank ,  Paul Lubock ,  Michael L. Jones ,  Richard L. Quick ,  Frank Louw ,  Stephen A. De Santis

IPC分类号： A61B19/00

CPC分类号： A61M37/0069 ,  A61B6/12 ,  A61B8/0833 ,  A61B10/02 ,  A61B90/39 ,  A61B2017/00004 ,  A61B2090/08021 ,  A61B2090/3908 ,  A61B2090/3925 ,  A61B2090/3987 ,  A61K49/006 ,  A61K49/222

摘要： The invention is directed biopsy site markers and methods of marking a biopsy site, so that the location of the biopsy cavity is readily visible by conventional imaging methods, particularly by ultrasonic imaging. The biopsy site markers of the invention have high ultrasound reflectivity, presenting a substantial acoustic signature from a small marker, so as to avoid obscuring diagnostic tissue features in subsequent imaging studies, and can be readily distinguished from biological features. The several disclosed embodiments of the biopsy site marker of the invention have a high contrast of acoustic impedance as placed in a tissue site, so as to efficiently reflect and scatter ultrasonic energy, and preferably include gas-filled internal pores. The markers may have a non-uniform surface contour to enhance the acoustic signature. The markers have a characteristic form which is recognizably artificial during medical imaging. The biopsy site marker may be accurately fixed to the biopsy site so as to resist migration from the biopsy cavity when a placement instrument is withdrawn, and when the marked tissue is subsequently moved or manipulated.

摘要翻译： 本发明涉及活检部位标记和标记活组织检查部位的方法，使得活检腔的位置通过常规成像方法，特别是通过超声成像容易看到。 本发明的活检部位标记物具有高的超声反射率，从小标记物呈现出实质的声学特征，以避免在随后的成像研究中掩盖诊断组织特征，并且可以容易地与生物特征区别开来。 本发明的活检部位标记物的几个公开的实施方案具有放置在组织部位中的声阻抗的高对比度，以便有效地反射和散射超声能量，并且优选地包括气体填充的内部孔。 标记可以具有不均匀的表面轮廓以增强声学特征。 标记具有在医学成像期间可识别人造的特征形式。 可以将活检部位标记物精确地固定到活检部位，以便当放置放置器械被取出时以及随后移动或操纵标记的组织时抵抗活组织腔的迁移。

公开(公告)号：US20090137928A1

公开(公告)日：2009-05-28

申请号：US12290961

申请日：2008-11-05

申请人： Richard L. Quick ,  Martin V. Shabaz ,  Frank R. Louw ,  Paul Lubock ,  Jason H. Safabash

发明人： Richard L. Quick ,  Martin V. Shabaz ,  Frank R. Louw ,  Paul Lubock ,  Jason H. Safabash

IPC分类号： A61B10/00

CPC分类号： A61B17/32002 ,  A61B10/0275 ,  A61B10/0283 ,  A61B2010/0208 ,  A61B2010/0225 ,  A61B2017/00473

摘要： The invention is directed to a system and method for separating and collecting one or more tissue specimens from a target site within a patient and flushing the specimen to remove blood, debris and the like before the specimen is removed from the biopsy device. The flow of flushing fluid to the tissue collector is preferably controlled to coincide with delivery of one or more specimens to the collecting tray or basket of the device or after the receipt of the specimen within the tissue collector to ensure that the fluid is applied to a fresh specimen. The tissue tray or basket within the tissue collector has an open or foraminous portion to facilitate removal of fluid, such as the applied fluid and blood, and other debris from the tissue specimens on the tray. Vacuum is provided within the tissue collector, preferably under the tray to remove fluid and debris from the collector interior.

摘要翻译： 本发明涉及一种用于从患者内的目标部位分离和收集一个或多个组织样本的系统和方法，并且在从活检装置移除样本之前冲洗样本以除去血液，碎屑等。 冲洗流体到组织收集器的流动优选地被控制以与一个或多个样品递送到装置的收集盘或篮子之间或者在组织收集器内接收到样本之后确保将流体施加到 新鲜标本。 组织收集器内的纸巾托盘或篮子具有开放或有孔的部分，以有助于从托盘上的组织标本中去除流体，例如所施加的流体和血液以及其它碎屑。 在组织收集器内提供真空，优选在托盘下面，以从收集器内部去除流体和碎屑。

公开(公告)号：US20090043328A1

公开(公告)日：2009-02-12

申请号：US11981007

申请日：2007-10-31

申请人： Jill Delsman

发明人： Jill Delsman

IPC分类号： A61B17/34 ,  A61M25/10

CPC分类号： A61M25/0662 ,  A61B17/3415 ,  A61B17/3431 ,  A61B90/03 ,  A61B2090/037 ,  A61B2090/038 ,  A61B2090/0801

摘要： A trocar assembly including a trocar and a trocar sheath and methods for accessing an intracorporeal site, e.g. biopsy or trocar site, using the trocar assembly. The trocar has a tissue penetrating distal tip, an elongated shaft and a proximal handle portion. The distal portion of the trocar sheath forms a releasable connection, such as a friction fit, with the shaft of the trocar and a slit that extends from the distal portion to the proximal end of the trocar sheath. The trocar assembly is advanced through the patient's tissue until the distal end of the trocar sheath is located at the desired site and then the trocar is removed. A treatment device such as a radiation balloon catheter is advanced through the interior of the sheath until the treatment component thereof is at the desired site.

公开(公告)号：US20090030405A1

公开(公告)日：2009-01-29

申请号：US12220389

申请日：2008-07-24

申请人： Richard L. Quick ,  Martin V. Shabaz ,  James H. Dabney ,  Dan Kussman ,  Frank R. Louw ,  Paul Lubock

发明人： Richard L. Quick ,  Martin V. Shabaz ,  James H. Dabney ,  Dan Kussman ,  Frank R. Louw ,  Paul Lubock

IPC分类号： A61B17/00

CPC分类号： A61B10/02 ,  A61B5/01 ,  A61B5/024 ,  A61B10/0266 ,  A61B10/0283 ,  A61B18/14 ,  A61B90/06 ,  A61B2017/00199 ,  A61B2017/00225 ,  A61B2017/00482 ,  A61B2017/008 ,  A61B2017/00973

摘要： A control consol is disclosed for controlling one or more medical devices. The control consol communicates to at least one medical device, and at least one peripheral module associated with the medical device if needed. The control consol has a microprocessor for processing data to direct an operation of the medical device.

摘要翻译： 公开了一种用于控制一个或多个医疗装置的控制组件。 如果需要，控制组件与至少一个医疗设备以及与医疗设备相关联的至少一个外围模块通信。 控制组件具有用于处理数据以指导医疗设备的操作的微处理器。

公开(公告)号：US20080009728A1

公开(公告)日：2008-01-10

申请号：US11810425

申请日：2007-06-05

申请人： Lloyd Malchow ,  Paul Lubock ,  Derek Daw

发明人： Lloyd Malchow ,  Paul Lubock ,  Derek Daw

IPC分类号： A61B8/00 ,  A61B10/02

CPC分类号： A61B10/0283 ,  A61B8/0833 ,  A61B8/0841 ,  A61B8/4405 ,  A61B8/4472 ,  A61B2017/00199 ,  A61B2090/378

摘要： A biopsy system is disclosed that has a tissue removal system, an imaging system, an image display system and a common input console for these systems. The tissue removal system can have a mechanical tissue cutting blade or an electrosurgical cutting element and the tissue removal system is capable of handling both tissue cutting configurations. The imaging system is preferably an ultrasound imaging system and the image display system has a video screen for displaying diagnostic ultrasound images from an ultrasound probe. The common input console preferably has a touch screen display and a keyboard to facilitate operation of the tissue removal system, the ultrasound imaging system and the image display system from the same console.

公开(公告)号：US20070191667A1

公开(公告)日：2007-08-16

申请号：US11593678

申请日：2006-11-06

申请人： Paul Lubock ,  Michael L. Jones

发明人： Paul Lubock ,  Michael L. Jones

IPC分类号： A61N5/00

CPC分类号： A61N5/1015 ,  A61B2017/3419 ,  A61N2005/1005

摘要： Devices and methods are disclosed for treatment to tissue surrounding a body cavity or other intracorporeal site, such as after removal of tissue, e.g. cancer. Such a device includes a treatment location on a distal portion of the device with one or more radiation shielding components that partially encircle a radiation source at the treatment location to control emitted radiation from the radiation source. The device minimizes radiation damage to healthy tissue surrounding the body cavity or other site while irradiating tissue not shielded by the radiation shielding components. A device embodying features of the invention can include a sealing member at a location on a shaft of the device proximal to a treatment location to seal the passageway leading to the body cavity.

摘要翻译： 公开了用于治疗围绕体腔或其他体内部位的组织的装置和方法，例如在去除组织后，例如， 癌症。 这种装置包括在装置的远端部分上的处理位置，其中一个或多个辐射屏蔽部件在处理位置部分地环绕辐射源以控制来自辐射源的辐射。 该装置最小化对体腔或其他部位周围的健康组织的辐射损伤，同时辐射未被辐射屏蔽部件屏蔽的组织。 体现本发明特征的装置可包括密封构件，该密封构件位于靠近处理位置的装置的轴上的位置处，以密封通向体腔的通道。

公开(公告)号：US07189206B2

公开(公告)日：2007-03-13

申请号：US10374915

申请日：2003-02-24

申请人： Richard L. Quick ,  Frank Louw ,  Paul Lubock ,  Martin V. Shabaz

发明人： Richard L. Quick ,  Frank Louw ,  Paul Lubock ,  Martin V. Shabaz

IPC分类号： A61B10/00

CPC分类号： A61B10/0233 ,  A61B10/02 ,  A61B10/0266 ,  A61B10/0275 ,  A61B10/0283 ,  A61B17/32002 ,  A61B17/3417 ,  A61B90/30 ,  A61B90/39 ,  A61B2010/0208 ,  A61B2010/0225 ,  A61B2017/0046 ,  A61B2017/00473 ,  A61B2017/3405 ,  A61B2017/3454 ,  A61B2090/0811 ,  A61B2090/309 ,  B23Q17/2404 ,  F21V33/0068

摘要： The invention is directed to devices and methods for accessing a desired target site within a patient's body and for separating and collecting a tissue specimen from the target site. The device includes a probe member or cannula with a penetrating distal tip, and a tissue cutting member which is disposed within the probe member to cut a tissue specimen from supporting tissue at the biopsy site. This probe is releasably secured to a housing to provide a plurality of discrete orientations of the probe about its longitudinal axis. Vacuum may be provided to the inner lumen of the cutting member to transport tissue through the inner lumen thereof. Rotation (and optionally longitudinal reciprocation) of the tissue cutter is effective to separate a tissue specimen from surrounding tissue at the target site. Vacuum or fluid pressure may be used to move the specimen cut from the target site proximally within the inner lumen defined at least in part by the culling member for collection.

摘要翻译： 本发明涉及用于访问患者体内期望的目标部位并用于从目标部位分离和收集组织标本的装置和方法。 该装置包括具有穿透性远侧末端的探针构件或套管，以及组织切割构件，其设置在探针构件内以从活组织检查部位的支撑组织切割组织样本。 该探针可释放地固定到壳体以提供探针围绕其纵向轴线的多个离散定向。 可以向切割构件的内腔提供真空以将组织输送通过其内腔。 组织切割器的旋转（和任选的纵向往复运动）有效地将组织标本与目标部位的周围组织分离。 可以使用真空或流体压力将从目标位置切割的样本移动到内部腔内的至少一部分由剔除构件限定以用于收集的内腔。