公开(公告)号：US08894644B2

公开(公告)日：2014-11-25

申请号：US12855177

申请日：2010-08-12

Applicant: Manfred Stieber ,  Klaus-Dieter Weltmann ,  Thomas Von Woedtke ,  Christian Wilke ,  Uwe Ehrenberg

Inventor： Manfred Stieber ,  Klaus-Dieter Weltmann ,  Thomas Von Woedtke ,  Christian Wilke ,  Uwe Ehrenberg

IPC: A61B18/12 ,  A61N1/44 ,  A61L2/00 ,  A61L2/14 ,  A61N1/04 ,  A61N1/32 ,  C12N13/00 ,  H05H1/24

CPC classification number: A61N1/44 ,  A61L2/0011 ,  A61L2/14 ,  A61N1/0412 ,  A61N1/327 ,  C12M35/02 ,  C12N13/00 ,  H05H1/24 ,  H05H1/2406 ,  H05H2001/2412 ,  H05H2245/122

Abstract: A method and device for treatment of living cells with cold atmospheric pressure plasma while simultaneously applying selective electroporation of the cells are provided. The method is useful for the local selective killing of cancer cells, improvement of wound treatment and sterilization or decontamination of objects.

Abstract translation: 提供了一种用于处理具有冷气压等离子体的活细胞同时施加细胞选择性电穿孔的方法和装置。 该方法可用于局部选择性杀死癌细胞，改善伤口治疗和灭菌或物体去污。

公开(公告)号：US08828326B2

公开(公告)日：2014-09-09

申请号：US13510030

申请日：2010-11-11

Applicant: Thomas Bickford Holbeche

Inventor： Thomas Bickford Holbeche

IPC: B01J19/08 ,  A61C17/16

CPC classification number: A61C17/02 ,  H05H1/2406 ,  H05H2240/20 ,  H05H2245/122 ,  H05H2245/125

Abstract: The present invention provides a device 10 for generating a non-thermal gaseous plasma which may be a flow of gas plasma in the form of a gas plasma plume emitted from the device. The device comprises a gas capsule, or pressure vessel, 12 for holding a gas or gases 14 under pressure and forming a flow of gas through a plasma generator 16 to an applicator 18 when released from the capsule. Gas released from the gas capsule is energised in the reaction generator to form a gas plasma.The device has a housing 28 for the plasma generator 16, a battery 116 and a signal generator 58 for energising the plasma generator. The gas capsule 12 docks with the housing 28. The device is adapted to be hand-held, typically by the gas capsule 12, and operated to allow it to be used for instance for cleaning and whitening teeth.

Abstract translation: 本发明提供了一种用于产生非热气体等离子体的装置10，其可以是从装置发射的气体等离子体羽流形式的气体等离子体流。 该装置包括气体胶囊或压力容器12，用于在压力下保持气体14，并在从胶囊释放时通过等离子体发生器16形成气体流到涂敷器18。 从气囊释出的气体在反应发生器中通电，形成气体等离子体。 该装置具有用于等离子体发生器16的壳体28，电池116和用于激励等离子体发生器的信号发生器58。 气体胶囊12与壳体28对接。该装置通常由气囊12进行手持，并且被操作以允许其用于例如清洁和增白牙齿。

公开(公告)号：US20120282574A1

公开(公告)日：2012-11-08

申请号：US13510030

申请日：2010-11-11

Applicant: Thomas Bickford Holbeche

Inventor： Thomas Bickford Holbeche

IPC: A61C17/00

CPC classification number: A61C17/02 ,  H05H1/2406 ,  H05H2240/20 ,  H05H2245/122 ,  H05H2245/125

Abstract: The present invention provides a device 10 for generating a non-thermal gaseous plasma which may be a flow of gas plasma in the form of a gas plasma plume emitted from the device. The device comprises a gas capsule, or pressure vessel, 12 for holding a gas or gases 14 under pressure and forming a flow of gas through a plasma generator 16 to an applicator 18 when released from the capsule. Gas released from the gas capsule is energised in the reaction generator to form a gas plasma.The device has a housing 28 for the plasma generator 16, a battery 116 and a signal generator 58 for energising the plasma generator. The gas capsule 12 docks with the housing 28. The device is adapted to be hand-held, typically by the gas capsule 12, and operated to allow it to be used for instance for cleaning and whitening teeth.

Abstract translation: 本发明提供了一种用于产生非热气体等离子体的装置10，其可以是从装置发射的气体等离子体羽流形式的气体等离子体流。 该装置包括气体胶囊或压力容器12，用于在压力下保持气体14，并在从胶囊释放时通过等离子体发生器16形成气体流到涂敷器18。 从气囊释出的气体在反应发生器中通电，形成气体等离子体。 该装置具有用于等离子体发生器16的壳体28，电池116和用于激励等离子体发生器的信号发生器58。 气体胶囊12与壳体28对接。该装置通常由气囊12进行手持，并且被操作以允许其用于例如清洁和增白牙齿。

公开(公告)号：US20120267322A1

公开(公告)日：2012-10-25

申请号：US13498360

申请日：2010-10-03

Applicant: Reuven Lev Boxman ,  Vladimir Dikhtiar ,  Olga Dikhtyar ,  Nahum Parkansky

Inventor： Reuven Lev Boxman ,  Vladimir Dikhtiar ,  Olga Dikhtyar ,  Nahum Parkansky

IPC: A61L2/14 ,  H05B6/74 ,  C02F1/32 ,  C02F9/12 ,  B82Y40/00

CPC classification number: H05H1/46 ,  H05H2001/4622 ,  H05H2245/122

Abstract: A system for plasma treatment of a liquid and corresponding uses thereof, the system comprising a chamber having a liquid input conduit and a liquid output conduit, a source of electromagnetic radiation of wavelength λ coupled to the chamber by a waveguide of appropriate width to provide only fundamental mode of the electromagnetic radiation, a focusing means positioned between the waveguide and the chamber for transmissively focusing the electromagnetic radiation incident thereon to a location within the chamber remote from walls of chamber for creating a plasma at the location, characterized in that the plasma is formed entirely within the liquid.

Abstract translation: 用于等离子体处理液体的系统及其相应的用途，该系统包括具有液体输入导管和液体输出导管的室，波长λ的电磁辐射源通过适当宽度的波导耦合到腔室，以仅提供 电磁辐射的基本模式，位于波导和腔室之间的聚焦装置，用于将入射到其上的电磁辐射透射聚焦到远离腔室壁的室内的位置，以在该位置产生等离子体，其特征在于等离子体 完全在液体内形成。

公开(公告)号：US20120141321A1

公开(公告)日：2012-06-07

申请号：US13381405

申请日：2009-06-29

Applicant: Nofel Merbahi ,  Mohammed Yousfi ,  Olivier Eichwald

Inventor： Nofel Merbahi ,  Mohammed Yousfi ,  Olivier Eichwald

IPC: A61L2/03 ,  A61M37/00 ,  H05H1/48

CPC classification number: H05H1/48 ,  H05H2001/483 ,  H05H2245/122

Abstract: Device for emitting a plasma jet at ambient pressure and temperature, includes an electric-field generator for generating discharges between an anode assembly and a cathode assembly. The cathode assembly defines an inter-cathode dielectric space that extends inside the cathode assembly and is opposite at least one cathode surface of the cathode assembly, and has at least one cathode opening extending outside the inter-cathode space, the cathode opening being defined by at least one active edge of the cathode surface, the active edge(s) extending in a cathode opening plane. The anode assembly includes at least one pointed portion that is oriented toward the outside of the inter-cathode space and is laterally and deeply placed relative to the cathode opening. The pointed portion extends up to the cathode opening plane, for causing a plasma jet emission that is spontaneously sprayed in a predetermined direction toward the outside of the inter-cathode space.

Abstract translation: 用于在环境压力和温度下发射等离子体射流的装置包括用于在阳极组件和阴极组件之间产生放电的电场发生器。 阴极组件限定在阴极组件内部延伸并且与阴极组件的至少一个阴极表面相对的阴极间介电空间，并且具有延伸到阴极间空间外部的至少一个阴极开口，阴极开口由 阴极表面的至少一个有效边缘，所述有源边缘在阴极开口平面中延伸。 阳极组件包括至少一个朝着阴极间空间的外侧定向并且相对于阴极开口横向和深度放置的尖部。 尖端部分延伸到阴极开口平面，用于引起沿预定方向自发地喷射到阴极间空间外部的等离子体射流发射。

公开(公告)号：US20120080412A1

公开(公告)日：2012-04-05

申请号：US13082548

申请日：2011-04-08

Applicant: Thomas Bickford HOLBECHE ,  Richard Thomas Reich ,  Peter Dobson ,  Michael Wickham

Inventor： Thomas Bickford HOLBECHE ,  Richard Thomas Reich ,  Peter Dobson ,  Michael Wickham

IPC: B23K10/00

CPC classification number: A61B18/042 ,  H05H1/2406 ,  H05H2001/245 ,  H05H2240/20 ,  H05H2245/122

Abstract: The present invention provides a hand-held device 10 for providing a flow of plasma for treatment of a treatment region. The device comprises a plasma cell 16 defining a volume in which gas passing through a cell inlet from a gas source 22 can be energised to form a plasma and discharged through a cell outlet for treatment of a treatment region by said generated plasma, and a plurality of electrodes for receiving electrical power for energising gas in the cell to form a plasma, wherein the device comprises a valve arrangement 32 operable in an open condition to allow the discharge of plasma from the device to the treatment region and in a closed condition to resist the passage of ambient contaminants into the device in the absence of gas flow through the device from the gas source.

Abstract translation: 本发明提供一种用于提供治疗区域的血浆流的手持装置10。 该装置包括限定体积的等离子体单元16，其中通过来自气体源22的单元入口的气体可以被激发以形成等离子体并通过电池出口排出，以通过所产生的等离子体处理处理区域，并且多个 的电极，用于接收用于为电池中的气体供电以形成等离子体的电力，其中所述装置包括可在打开状态下操作的阀装置32，以允许将等离子体从装置排出到处理区域并且处于闭合状态以抵抗 在没有气体从气体源流过设备的情况下，环境污染物进入设备。

公开(公告)号：US20110112528A1

公开(公告)日：2011-05-12

申请号：US12855177

申请日：2010-08-12

Applicant: Manfred STIEBER ,  Klaus-Dieter Weltmann ,  Thomas Von Woedtke ,  Christian Wilke ,  Uwe Ehrenberg

Inventor： Manfred STIEBER ,  Klaus-Dieter Weltmann ,  Thomas Von Woedtke ,  Christian Wilke ,  Uwe Ehrenberg

IPC: A61B18/18 ,  C12M1/00 ,  A61L2/14

CPC classification number: A61N1/44 ,  A61L2/0011 ,  A61L2/14 ,  A61N1/0412 ,  A61N1/327 ,  C12M35/02 ,  C12N13/00 ,  H05H1/24 ,  H05H1/2406 ,  H05H2001/2412 ,  H05H2245/122

Abstract: A method and device for treatment of living cells with cold atmospheric pressure plasma while simultaneously applying selective electroporation of the cells are provided. The method is useful for the local selective killing of cancer cells, improvement of wound treatment and sterilization or decontamination of objects.

Abstract translation: 提供了一种用于处理具有冷气压等离子体的活细胞同时施加细胞选择性电穿孔的方法和装置。 该方法可用于局部选择性杀死癌细胞，改善伤口治疗和灭菌或物体去污。

公开(公告)号：US20100171425A1

公开(公告)日：2010-07-08

申请号：US12451139

申请日：2008-03-25

Applicant: Roland Gesche ,  Andreea Cristina Andrei ,  Stephan Buchholz ,  Silvio Kuehn

Inventor： Roland Gesche ,  Andreea Cristina Andrei ,  Stephan Buchholz ,  Silvio Kuehn

IPC: H05H1/46 ,  H01J61/06

CPC classification number: H05H1/46 ,  H05H2001/463 ,  H05H2240/10 ,  H05H2245/122 ,  H05H2277/11

Abstract: The invention relates to an electrode for a plasma generator for generating plasmas at atmospheric pressure or near-atmospheric pressures by means of excitation using microwaves. The invention provides an electrode made of a sheet metal strip (1), in the longitudinal direction of which at least one slot (2) is introduced at a length that is one time or multiple times that of a quarter of the wavelength of the open-circuit voltage of the microwave such that at least two partial electrodes (3) are formed, wherein the voltage supply line is provided on the partial electrodes (3) in the region of the closed slot end or ends.

Abstract translation: 本发明涉及一种用于等离子体发生器的电极，用于通过使用微波的激发在大气压或近似大气压下产生等离子体。 本发明提供了一种由金属板条（1）制成的电极，其长度方向上至少有一个槽（2）的长度是开口波长的四分之一的一倍或多倍 微波的电路电压使得形成至少两个部分电极（3），其中在封闭槽端或端部的区域中，电压供应线设置在部分电极（3）上。

公开(公告)号：US07357802B2

公开(公告)日：2008-04-15

申请号：US10779529

申请日：2004-02-13

Applicant: Daniel V. Palanker ,  Alexander Vankov

Inventor： Daniel V. Palanker ,  Alexander Vankov

IPC: A61B18/18

CPC classification number: A61B18/1402 ,  A61B2018/00083 ,  A61B2018/1407 ,  A61B2018/1412 ,  A61B2018/144 ,  H05H1/48 ,  H05H2245/122

Abstract: The present invention is directed towards an electrosurgical cutting system. The system comprises an electrically conductive blade, having first and second blade surfaces. First and second insulators are affixed to the first and second blade surfaces, respectively. A blade edge, a region between the first and second blade surfaces, has an edge radius of curvature, which preferably is small. A source of pulsed electrical energy coupled to the electrically conductive blade provides a substantially uniform and highly enhanced electric field along a cutting portion of the blade edge.The system can also be comprised of a wire electrode. Despite the fact that its field is strongly enhanced around the apex, a uniform vapor cavity is formed and then ionized using an appropriately designed burst of pulses, preferably of alternating polarity.

Abstract translation: 本发明涉及电外科切割系统。 该系统包括具有第一和第二叶片表面的导电叶片。 第一和第二绝缘体分别固定在第一和第二叶片表面上。 叶片边缘，第一和第二叶片表面之间的区域具有边缘曲率半径，其优选地较小。 耦合到导电叶片的脉冲电能源沿叶片边缘的切割部分提供基本均匀且高度增强的电场。 该系统还可以由线电极组成。 尽管它的场强在周围的顶点强烈增强，形成均匀的气腔，然后使用适当设计的脉冲脉冲进行电离，优选地具有交替的极性。

公开(公告)号：US20070239156A1

公开(公告)日：2007-10-11

申请号：US11726782

申请日：2007-03-22

Applicant: Daniel Palanker ,  Alexander Vankov

Inventor： Daniel Palanker ,  Alexander Vankov

IPC: A61B18/08

CPC classification number: A61B18/14 ,  A61B18/042 ,  A61B2018/00577 ,  A61B2018/00601 ,  A61B2018/00625 ,  A61B2018/1213 ,  A61B2018/122 ,  A61B2018/1472 ,  H05H1/48 ,  H05H2245/122

Abstract: An apparatus and method for cutting a material including conducting and non-conducting materials such as biological tissue, cellulose or plastic while the material is submerged in a conductive liquid medium. The apparatus has a cutting electrode with an elongate cutting portion having an aspect ratio (length to width) of 1 or more and a return electrode. The two electrodes are immersed in the conductive medium and a voltage is applied between them to heat the medium, thus producing a vapor cavity around the elongate cutting portion and ionizing a gas inside the vapor cavity to produce a plasma. The voltage applied between the electrodes is modulated in pulses having a modulation format selected to minimize the size of the vapor cavity, its rate of formation and heat diffusion into the material while the latter is cut with an edge of the elongate cutting portion. The modulation format includes pulses ranging in duration from 10 μs to 10 ms, as well as minipulses and micropulses, as necessary. The apparatus and method of invention allow the user to perform efficient thermal ablation and electrosurgical procedures in particular at power levels as low as 10 mW with minimal thermal and cavitation damage.