公开(公告)号：US08529454B2

公开(公告)日：2013-09-10

申请号：US12747428

申请日：2008-12-10

Applicant: Jingkuang Chen

Inventor： Jingkuang Chen

IPC: A61B8/00 ,  G02B6/30

CPC classification number: A61B5/0095 ,  A61B5/0086 ,  A61B5/02007 ,  A61B8/0833 ,  A61B8/12 ,  A61B8/4472 ,  A61B8/4483 ,  A61B8/483 ,  A61B2562/028 ,  Y10T29/49826

Abstract: A photoacoustic medical imaging device may include a substrate, an array of ultrasonic transducers on the substrate, at least one groove etched on the substrate, at least one optical fiber, and at least one facet. Each optical fiber is disposed in one of the grooves. Each facet is etched in one of the grooves and coated with a layer of metal having high infrared reflectivity. Each optical fiber is configured to guide infrared light from a light source through the fiber and toward the respective facet. The facet is configured to reflect the infrared light toward a target.

公开(公告)号：US08515201B1

公开(公告)日：2013-08-20

申请号：US12586276

申请日：2009-09-18

Applicant: Victor Manuel Murray Herrera ,  Marios Stephanou Pattichis ,  Peter Soliz ,  Carla Paola Agurto Rios ,  Herbert T. Davis, III

Inventor： Victor Manuel Murray Herrera ,  Marios Stephanou Pattichis ,  Peter Soliz ,  Carla Paola Agurto Rios ,  Herbert T. Davis, III

IPC: G06K9/40

CPC classification number: G06K9/527

Abstract: Image and video processing using multi-scale amplitude-modulation frequency-modulation (“AM-FM”) demodulation where a multi-scale filterbank with bandpass filters that correspond to each scale are used to calculate estimates for instantaneous amplitude, instantaneous phase, and instantaneous frequency. The image and video are reconstructed using the instantaneous amplitude and instantaneous frequency estimates and variable-spacing local linear phase and multi-scale least square reconstruction techniques. AM-FM demodulation is applicable in imaging modalities such as electron microscopy, spectral and hyperspectral devices, ultrasound, magnetic resonance imaging (“MRI”), positron emission tomography (“PET”), histology, color and monochrome images, molecular imaging, radiographs (“X-rays”), computer tomography (“CT”), and others. Specific applications include fingerprint identification, detection and diagnosis of retinal disease, malignant cancer tumors, cardiac image segmentation, atherosclerosis characterization, brain function, histopathology specimen classification, characterization of anatomical structure such as carotid artery walls and plaques or cardiac motion and as the basis for computer-aided diagnosis to name a few.

Abstract translation: 使用多尺度幅度调制调制（“AM-FM”）解调的图像和视频处理，其中使用对应于每个刻度的带通滤波器的多尺度滤波器组来计算瞬时幅度，瞬时相位和瞬时幅度的估计 频率。 使用瞬时幅度和瞬时频率估计和可变间距局部线性相位和多尺度最小二乘重建技术重构图像和视频。 AM-FM解调适用于电子显微镜，光谱和超光谱装置，超声，磁共振成像（“MRI”），正电子发射断层扫描（“PET”），组织学，彩色和单色图像，分子成像，X线片等成像模式 （“X射线”），计算机断层扫描（“CT”）等。 具体应用包括指纹识别，视网膜疾病的检测和诊断，恶性肿瘤，心脏图像分割，动脉粥样硬化特征，脑功能，组织病理学标本分类，解剖结构如颈动脉壁和斑块或心脏运动的表征，并作为基础 计算机辅助诊断等等。

公开(公告)号：US08482465B1

公开(公告)日：2013-07-09

申请号：US13004004

申请日：2011-01-10

Applicant: Sameer D. Hemmady ,  Ganesh Balakrishnan ,  Christos G. Christodoulou ,  Youssef Tawk

Inventor： Sameer D. Hemmady ,  Ganesh Balakrishnan ,  Christos G. Christodoulou ,  Youssef Tawk

IPC: H01Q1/36

CPC classification number: H01Q9/04 ,  H01Q1/36

Abstract: Various embodiments provide materials and methods for an optically pumped switch device, an optically pumped reconfigurable antenna system (OPRAS), and their related antenna devices. In one embodiment, the switch devices and the antenna devices can have a photoconductive cell. The photoconductive cell can include a semiconductive substrate that is conductive to reflect a radio frequency (RF) signal in response to an optical signal.

Abstract translation: 各种实施例提供了用于光泵浦开关装置，光泵浦可重构天线系统（OPRAS）及其相关天线装置的材料和方法。 在一个实施例中，开关装置和天线装置可以具有光导电池。 光导电池可以包括导电的半导体衬底，以响应于光信号反射射频（RF）信号。

公开(公告)号：US20130169276A1

公开(公告)日：2013-07-04

申请号：US13776580

申请日：2013-02-25

Applicant: STC.UNM

Inventor： Laurel Sillerud ,  Todd M. Alam ,  Andrew F. McDowell

IPC: G01R33/30 ,  G01R33/465

CPC classification number: G01R33/32 ,  B82Y15/00 ,  G01N24/08 ,  G01N33/54326 ,  G01N33/553 ,  G01R33/281 ,  G01R33/302 ,  G01R33/34007 ,  G01R33/34046 ,  G01R33/34092 ,  G01R33/341 ,  G01R33/465 ,  G01R33/5601

Abstract: A biological detector includes a conduit for receiving a fluid containing one or more magnetic nanoparticle-labeled, biological objects to be detected and one or more permanent magnets or electromagnet for establishing a low magnetic field in which the conduit is disposed. A microcoil is disposed proximate the conduit for energization at a frequency that permits detection by NMR spectroscopy of whether the one or more magnetically-labeled biological objects is/are present in the fluid.

Abstract translation: 生物检测器包括用于接收含有一个或多个待纳入检测体的磁性纳米颗粒标记的生物体的流体的导管，以及一个用于建立其中设置导管的低磁场的永磁体或电磁体。 微线圈靠近导管设置，以允许通过NMR光谱法检测流体中是否存在一个或多个磁性标记的生物体的频率。

公开(公告)号：US08455856B1

公开(公告)日：2013-06-04

申请号：US13078368

申请日：2011-04-01

Applicant: Stephen D. Hersee

Inventor： Stephen D. Hersee

IPC: H01L29/06

CPC classification number: H01L27/15 ,  H01L25/167 ,  H01L29/2003 ,  H01L29/7787 ,  H01L33/0041 ,  H01L33/06 ,  H01L2224/32225 ,  H01L2924/0002 ,  H01L2924/00

Abstract: Various embodiments provide materials and methods for integrating exemplary heterostructure field-effect transistor (HFET) driver circuit or thyristor driver circuit with LED structures to reduce or eliminate resistance and/or inductance associated with their conventional connections.

Abstract translation: 各种实施例提供用于将示例性异质结构场效应晶体管（HFET）驱动器电路或晶闸管驱动器电路与LED结构集成以减少或消除与其常规连接相关联的电阻和/或电感的材料和方法。

公开(公告)号：US08440231B2

公开(公告)日：2013-05-14

申请号：US13601532

申请日：2012-08-31

Applicant: Hugh D. Smyth ,  Martin J. Donovan

Inventor： Hugh D. Smyth ,  Martin J. Donovan

IPC: A61K9/00 ,  A61K9/12 ,  A61K9/14

CPC classification number: A61K9/0073 ,  A61K9/0075 ,  A61K9/0078 ,  A61K9/1641 ,  A61K47/60 ,  A61K47/6949 ,  A61K48/00 ,  B82Y5/00 ,  Y10T428/2982

Abstract: Swellable particles for delivery of a drug or other working agent to the pulmonary system are provided. The swellable particles include a dehydrated (dry) aerodynamic particle diameter of 5 μm or less to enable delivery to the respiratory tract, such as for example to the tracheo-bronchial airways of the upper respiratory tract and/or to the alveolic regions of the deep lung, and a hydrated particle diameter that is greater than 6 μm volume mean diameter to retard or prevent their phagocytosis by the macrophages present in airways of the respiratory tract.

Abstract translation: 提供了用于将药物或其它工作剂递送至肺部系统的可溶胀颗粒。 可溶胀颗粒包括5毫米或更小的脱水（干燥）空气动力学颗粒直径以能够输送到呼吸道，例如上呼吸道的气管支气管气道和/或深部的肺泡支气管气道 肺，以及大于6μm体积平均直径的水合粒径，以阻止或阻止其由呼吸道气道中的巨噬细胞吞噬。

公开(公告)号：US08435489B2

公开(公告)日：2013-05-07

申请号：US13309972

申请日：2011-12-02

Applicant: Jeffrey P. Norenberg ,  Richard S. Larson

Inventor： Jeffrey P. Norenberg ,  Richard S. Larson

IPC: A61K51/00 ,  A61M36/14

CPC classification number: C07F5/003 ,  A61K47/22 ,  A61K49/106 ,  A61K51/0474 ,  A61K51/0482 ,  A61K51/0485 ,  A61K51/0497 ,  C07F9/94

Abstract: The present invention is directed to novel non-invasive diagnostic tools to image cancers, especially, leukemia and non-Hodgkin's lymphomas (NHL) with minimal toxicity in vivo. The present invention represents a clear advance in the art which presently relies on tissue biopsy for diagnoses of these cancers. The novel imaging probe is capable of detecting precancerous cells, as well as their metastatic spread in tissues. This represents a quantum step forward in the diagnosis and staging of NHL using non-invasively molecular imaging techniques. This novel probe will also be useful to monitor patients response to chemotherapy treatments and other interventions or therapies used in the treatment of NHL. Compounds according to the present invention may be used as diagnostic tools for a number of conditions and diseases states as well as therapeutic agents for treating such conditions and disease states.

Abstract translation: 本发明涉及用于对癌症特别是白血病和非霍奇金淋巴瘤（NHL）进行成像的新型非侵入性诊断工具，其体内毒性最小。 本发明代表了目前依赖于组织活检以诊断这些癌症的本领域的明显进步。 该新型成像探针能够检测癌前细胞，以及它们在组织中的转移扩散。 这代表了使用非侵入性分子成像技术在NHL的诊断和分期中向前推进的量子进程。 该新型探针也可用于监测患者对化疗治疗的反应和用于治疗NHL的其他干预措施或疗法。 根据本发明的化合物可以用作许多病症和疾病状态的诊断工具以及用于治疗这些病症和疾病状态的治疗剂。

公开(公告)号：US08426501B1

公开(公告)日：2013-04-23

申请号：US13106814

申请日：2011-05-12

Applicant: Mahmoud Reda Taha ,  Usama Farid Kandil ,  Eslam Soliman

Inventor： Mahmoud Reda Taha ,  Usama Farid Kandil ,  Eslam Soliman

IPC: C04B14/38 ,  C04B28/00

CPC classification number: C04B28/02 ,  C04B14/026 ,  C04B20/1029 ,  C04B24/2611 ,  C04B24/2641 ,  C04B24/2676 ,  C04B24/281 ,  C04B24/283 ,  C04B24/287 ,  C04B24/307

Abstract: Exemplary embodiments provide materials and methods for forming CNTs-polymer composites (e.g., CNTs-SBR latex nano-composites and/or CNTs-epoxy nano-composites), CNTs-polymer concrete, and CNTs-polymer modified cementitious composites. In one embodiment, a plurality of CNTs and a surfactant-containing polymer, including a surfactant attached to a polymer chain, can be dispersed within a cementitious matrix to form a CNTs-polymer modified cementitious composite with the surfactant non-covalently bonded to one or more CNTs.

Abstract translation: 示例性实施例提供用于形成CNT-聚合物复合材料（例如，CNTs-SBR胶乳纳米复合材料和/或CNT-环氧纳米复合材料），CNT-聚合物混凝土和CNT-聚合物改性的水泥复合材料的材料和方法。 在一个实施方案中，多个CNT和含表面活性剂的聚合物（包括连接到聚合物链上的表面活性剂）可以分散在水泥基质中以形成CNT-聚合物改性的水泥质复合物，其中非共价键合到一个或多个 更多的CNTs。

公开(公告)号：US20130094077A1

公开(公告)日：2013-04-18

申请号：US13629598

申请日：2012-09-27

Applicant: Steven R.J. Brueck ,  Alexander Neumann ,  Yuliya Kuznetsova

Inventor： Steven R.J. Brueck ,  Alexander Neumann ,  Yuliya Kuznetsova

IPC: G02B21/06

CPC classification number: G02B21/06 ,  G01N2021/653 ,  G02B21/0056 ,  G02B21/365 ,  G06T3/4061

Abstract: In accordance with the aspects of the present disclosure, a method and apparatus is disclosed for imaging interferometric microscopy (IIM), which can use an immersion medium to enhance resolution up to a resolution of linear systems resolution limit of λ/4n, where λ is the wavelength in free space and n is the index of refraction of a transmission medium.

Abstract translation: 根据本公开的方面，公开了用于成像干涉显微镜（IIM）的方法和装置，其可以使用浸没介质来增强分辨率，直到λ/ 4n的线性系统分辨率极限的分辨率，其中λ是 自由空间中的波长和n是传输介质的折射率。

公开(公告)号：US20130074900A1

公开(公告)日：2013-03-28

申请号：US13665907

申请日：2012-10-31

Applicant: Richard I EPSTEIN ,  Kevin J. MALLOY

Inventor： Richard I EPSTEIN ,  Kevin J. MALLOY

IPC: H01L37/02 ,  F25B21/00

CPC classification number: H01L37/02 ,  F25B21/00 ,  F25B2321/001 ,  Y02B30/66 ,  Y10T29/49359

Abstract: In accordance with the invention, there are electrocaloric devices, pyroelectric devices and methods of forming them. A device which can be a pyroelectric energy generator or an electrocaloric cooling device, can include a first reservoir at a first temperature and a second reservoir at a second temperature, wherein the second temperature is higher than the first temperature. The device can also include a plurality of liquid crystal thermal switches disposed between the first reservoir and the second reservoir and one or more active layers disposed between the first reservoir and the second reservoir, such that each of the one or more active layers is sandwiched between two liquid crystal thermal switches. The device can further include one or more power supplies to apply voltage to the plurality of liquid crystal thermal switches and the one or more the active layers.

Abstract translation: 根据本发明，有电热装置，热电装置和形成它们的方法。 可以是热电能发生器或电热冷却装置的装置可以包括在第一温度下的第一储存器和在第二温度下的第二储存器，其中第二温度高于第一温度。 该装置还可以包括设置在第一储存器和第二储存器之间的多个液晶热开关和设置在第一储存器和第二储存器之间的一个或多个有源层，使得一个或多个有源层中的每一个夹在 两个液晶热开关。 该装置还可以包括一个或多个电源以向多个液晶热开关和一个或多个有源层施加电压。