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1.发明授权公开(公告)号：US12097020B2
公开(公告)日：2024-09-24
申请号：US18190723
申请日：2023-03-27
申请人： ACLARION, INC.
CPC分类号： A61B5/055 , A61B5/0075 , A61B5/4566 , A61B5/4824 , A61B5/7257 , G01R33/4625 , G01R33/4828 , G01R33/483 , G01R33/5608 , G06T7/0012 , Y10S128/922 , Y10S128/923
摘要： Systems and methods are provided for processing a set of multiple serially acquired magnetic resonance spectroscopy (MRS) free induction decay (FID) frames from a multi-frame MRS acquisition series from a region of interest (ROI) in a subject, and for providing a post-processed MRS spectrum. Processing parameters are dynamically varied while measuring results to determine the optimal post-processed results. Spectral regions opposite water from chemical regions of interest are evaluated and used in at least one processing operation. Frequency shift error is estimated via spectral correlation between free induction decay (FID) frames and a reference spectrum. Multiple groups of FID frames within the acquired set are identified to different phases corresponding with a phase step cycle of the acquisition. Baseline correction is also performed via rank order filter (ROF) estimate and a polynomial fit. Sections of the ROF may be excluded from the polynomial fit, such as for example sections determined to be associated with relevant spectral peaks.
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公开(公告)号：US20240277283A1
公开(公告)日：2024-08-22
申请号：US18652432
申请日：2024-05-01
申请人： TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED , NEW YORK SOCIETY FOR THE RELIFE OF THE RUPTURED AND CRIPPLED, MAINTAINNING THE HOSPITAL FOR SPECIAL
CPC分类号： A61B5/4566 , G06T7/0012 , G06T17/20 , G06T2200/08 , G06T2207/10028 , G06T2207/20081 , G06T2207/20084 , G06T2207/20101 , G06T2207/30012 , G06T2210/41
摘要： A method comprising: generating a parametrized three-dimensional (3D) body surface model on a training set comprising a plurality of 3D scans of subjects, wherein at least some of said 3D scans are of subjects having a skeletal deformity; receiving one or more target 3D scans of a target subject; optimizing said body surface model with respect to said one or more target 3D scans to calculate a target body surface model of said target subject; training a skeletal estimation model on a training set comprising: (i) body surface models of a plurality of subjects, and (ii) skeletal landmarks sets of said plurality of subjects; and applying said trained skeletal estimation model to said calculated target body surface model of said target subject, to estimate a skeletal shape of said target subject.
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公开(公告)号：US20240269095A1
公开(公告)日：2024-08-15
申请号：US18400189
申请日：2023-12-29
发明人： James Schroeder
CPC分类号： A61K31/19 , A61B5/026 , A61B5/14532 , A61B5/14546 , A61B5/4566 , A61K45/06
摘要： The claimed uses of bioidentical free D-BetaHydroxyButyric Acid as a method (1303), system (1411) and optional co-adjuvant compound for pharmaceutical co-administration with stroke therapeutic pharmaceutical compounds to treat stroke are novel, safe and not anticipated by the body of research spanning well over 75 years. Overall, no adverse findings have been reported within cell, animal and human safety studies at high dose levels with D-BetaHydroxyButyric acid which supports the safety and efficacy of the claimed uses at the anticipated usage levels for the disclosed applications.
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公开(公告)号：US20240095908A1
公开(公告)日：2024-03-21
申请号：US17993510
申请日：2022-11-23
申请人： Ortho AI LLC
发明人： Jonathan Vigdorchik , Seth Jerabek , David Mayman
CPC分类号： G06T7/0012 , A61B5/1121 , A61B5/4566 , A61B5/4571 , A61B5/742 , G06T7/11 , G06T7/60 , G06T7/73 , G06T2207/30012
摘要： A system and method for determining patient-specific anatomical parameters to improve surgical outcomes. Some embodiments include processes for predicting the parameters of occluded anatomy. Some embodiment includes processes for more accurately identifying a center point of a ball and socket joint, such as a center point or center of rotation of a femoral head. Some embodiments include processes for identify a patient-specific spinal curvature, including more precisely determining patient specific spinal inflection points. The various steps can be performed automatically through trained computing devices and graphically presented to a surgeon for review and any necessary modifications.
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公开(公告)号：US11877860B2
公开(公告)日：2024-01-23
申请号：US14535318
申请日：2014-11-06
申请人： NuVasive, Inc.
发明人： James E. Gharib , Eric Finley , Adam Azzara , Dmitry Novikov , William Taylor
CPC分类号： A61B5/4566 , A61B5/316 , A61B5/389 , A61B5/4836 , A61B5/4893 , A61B5/7246 , A61B17/025 , A61B17/0206 , A61B17/0218 , A61B5/743 , A61B2017/00039 , A61B2017/00115 , A61B2017/00199 , A61B2017/00929 , A61B2017/0256 , A61B2017/0262 , A61B2505/05 , A61B2560/0468
摘要： The present invention relates to a system and related methods for performing neurophysiologic assessments during surgical procedures. A method includes the steps of delivering a first transcutaneous, trans-abdominal stimulation signal to a spinal nerve root superior to a surgical target site; and determining a first neuromuscular response data set, based on transmission of said first transcutaneous, trans-abdominal stimulation signal, of a muscle located inferior to said surgical target site.
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公开(公告)号：US20180344309A1
公开(公告)日：2018-12-06
申请号：US16046503
申请日：2018-07-26
发明人： Namal Nawana , William C. Horton , William J. Frasier , Cody Cranson , Max Reinhardt , Mark T. Hall , Matthew Parsons , Jennifer DiPietro , Douglas Raymond , James Paiva
IPC分类号： A61B17/02 , G06Q10/10 , A61B34/10 , G01L5/00 , G06Q10/00 , A61B34/20 , A61B34/00 , G16H40/20 , G16H50/50 , G16H50/70 , G16H50/20 , G16H40/40 , G16H40/63 , G16H10/20 , A61B5/00 , A61B5/11 , A61B17/50 , A61B8/08 , A61B6/00 , A61B10/00 , A61B17/00
CPC分类号： A61B17/025 , A61B5/0022 , A61B5/1118 , A61B5/4509 , A61B5/4566 , A61B5/4571 , A61B5/4824 , A61B5/4833 , A61B5/4848 , A61B5/7282 , A61B5/742 , A61B5/746 , A61B5/7475 , A61B6/4494 , A61B6/485 , A61B6/506 , A61B8/08 , A61B17/02 , A61B17/50 , A61B34/10 , A61B34/20 , A61B34/25 , A61B2010/009 , A61B2010/0093 , A61B2017/00115 , A61B2017/00119 , A61B2017/0262 , A61B2034/101 , A61B2034/105 , A61B2034/2055 , A61B2034/2057 , A61B2034/252 , A61B2034/254 , A61B2034/256 , G01L5/00 , G06F19/00 , G06F19/321 , G06F19/325 , G06F19/3481 , G06Q10/00 , G06Q10/10 , G06Q50/24 , G16H10/20 , G16H40/20 , G16H40/40 , G16H40/63 , G16H50/20 , G16H50/50 , G16H50/70
摘要： Various systems and methods are provided for surgical and interventional planning, support, post-operative follow-up, and functional recovery tracking. In general, a patient can be tracked throughout medical treatment including through initial onset of symptoms, diagnosis, non-surgical treatment, surgical treatment, and recovery from the surgical treatment. In one embodiment, a patient and one or more medical professionals involved with treating the patient can electronically access a comprehensive treatment planning, support, and review system. The system can provide recommendations regarding diagnosis, non-surgical treatment, surgical treatment, and recovery from the surgical treatment based on data gathered from the patient and the medical professional(s). The system can manage the tracking of multiple patients, thereby allowing for data comparison between similar aspects of medical treatments and for learning over time through continual data gathering, analysis, and assimilation to decision-making algorithms.
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公开(公告)号：US20180325423A1
公开(公告)日：2018-11-15
申请号：US15774153
申请日：2015-11-06
申请人： ONEFIT MEDICAL
发明人： Christophe DROIT , Joe HOBEIKA , Rémi HUGONNET , Sébastien HENRY
CPC分类号： A61B5/1071 , A61B5/002 , A61B5/103 , A61B5/4561 , A61B5/4566 , A61B5/6878 , A61B5/6884 , A61B17/7074 , A61B2034/2048 , A61B2505/05 , A61B2562/0219 , A61B2562/04 , A61F2/44 , A61F2/4657 , A61F2002/4668
摘要： Disclosed is a sensor measuring patient spine vertebra angular orientation, including: a fastener, adapted to be fastened on a specific patient spine vertebra in a unique orientation relative to the specific vertebra, a support, solidary with the fastener in a unique orientation relative to the fastener, a detector, removably secured to the support in a unique orientation relative to the support and adapted to measure one or more parameters representative of the patient spine vertebra angular orientation.
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公开(公告)号：US20180140245A1
公开(公告)日：2018-05-24
申请号：US15356553
申请日：2016-11-19
申请人： Keijo Tapio Videman
发明人： Keijo Tapio Videman
CPC分类号： A61B5/407 , A61B5/0013 , A61B5/0022 , A61B5/055 , A61B5/103 , A61B5/4566 , A61B5/7275 , A61B2576/02 , G06T7/0012 , G06T2207/10088 , G06T2207/30012 , G16H30/40 , G16H50/20
摘要： Systems, computer-readable media, and methods for assessing morphometric measures of spinal vertebrae and inter-vertebral discs in a quantitative manner using imaging data and human body weight measures, for identification and prediction of structural spine pain, are described. The systems, media, and methods of the present disclosure utilize simple measurements of axial areas of vertebrae using endplate data of routinely acquired digital imaging pixels and body weight. More specifically, they provide a calculation pressure value based on one or more ratios from body weight and measurements of spinal structures and regions, which are readily determinable, e.g., through manual segmenting or automated programming of image analysis software.
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公开(公告)号：US20180132760A1
公开(公告)日：2018-05-17
申请号：US15574478
申请日：2016-06-01
发明人： John Louis Parker
CPC分类号： A61B5/1106 , A61B5/04001 , A61B5/05 , A61B5/202 , A61B5/4052 , A61B5/4238 , A61B5/4255 , A61B5/4519 , A61B5/4538 , A61B5/4566 , A61B5/4887 , A61B5/4893 , A61N1/00 , A61N1/205 , A61N1/3605 , A61N1/36057 , A61N1/36135 , A61N1/3615
摘要： A motor response of a muscle to neural stimulation is assessed. Electrical stimuli are applied from a first electrode to a selected neural pathway to evoke an efferent neural response. A slow neural response upon the neural pathway evoked by the electrical stimuli is observed. Based on the slow neural response, a motor response of at least one muscle to the stimuli is assessed.
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公开(公告)号：US20180110446A1
公开(公告)日：2018-04-26
申请号：US15568528
申请日：2016-04-22
申请人： Tintro Limited
发明人： Alan Chamberlain , Alison Marshall , Nigel John Walker , Stephen Aubrey Clark , Timothy James Barry
CPC分类号： A61B5/1121 , A61B5/11 , A61B5/1114 , A61B5/112 , A61B5/4566 , A61B5/6804 , A61B2562/0204 , A61B2562/0219
摘要： The invention discloses apparatus, and the method of using it, comprising one, or more, electronic sensors attached to a part(s) of a human or animal's body. The patient then performs an activity, or has an activity performed on them, and the results of the measured parameters are recorded by the sensor and processed, or downloaded and processed. The sensor may include a range of instrumentation, e.g. accelerometers, magnetometers, gyroscopes, force sensors, etc. to record positions (in the X, Y and Z planes), movements, angular movements, forces, stresses in bones/joints, etc. The use of the apparatus and method are appropriate to medical treatments, and perfecting sporting or dancing techniques and the results are processed to give the clinician or coach appropriate information to improve the problem being addressed. Methods for measuring lateral angular movement of hinged joints and spinal extension are taught.
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