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公开(公告)号：US20220348647A1
公开(公告)日：2022-11-03
申请号：US17853218
申请日：2022-06-29
Applicant: Janssen Biotech, Inc.
Inventor： Ken Boakye , Alfred Del Vecchio , John Kehoe , Eilyn Lacy , Lynne Murray , Mary Ryan , Sandra Santulli-Marotto , John Wheeler , Brian Whitaker , Alexey Teplyakov
IPC: C07K16/24
Abstract: The present invention relates to antibodies specifically binding CCL17, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing.
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公开(公告)号：US09944697B2
公开(公告)日：2018-04-17
申请号：US14534525
申请日：2014-11-06
Applicant: Janssen Biotech, Inc.
Inventor： Ken Boakye , Alfred Del Vecchio , John Kehoe , Eilyn Lacy , Lynne Murray , Mary Ryan , Sandra Santulli-Marotto , John Wheeler , Brian Whitaker , Alexey Teplyakov
CPC classification number: C07K16/24 , A61K39/00 , A61K2039/55522 , C07K2317/56 , C07K2317/565 , C07K2317/76 , C07K2317/92
Abstract: The present invention relates to antibodies specifically binding CCL17, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing.
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公开(公告)号：US20150125458A1
公开(公告)日：2015-05-07
申请号：US14534525
申请日：2014-11-06
Applicant: Janssen Biotech, Inc.
Inventor： Ken Boakye , Alfred Del Vecchio , John Kehoe , Eilyn Lacy , Lynne Murray , Mary Ryan , Sandra Santulli-Marotto , John Wheeler , Brian Whitaker , Alexey Teplyakov
IPC: C07K16/24
CPC classification number: C07K16/24 , A61K39/00 , A61K2039/55522 , C07K2317/56 , C07K2317/565 , C07K2317/76 , C07K2317/92
Abstract: The present invention relates to antibodies specifically binding CCL17, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing.
Abstract translation: 本发明涉及特异性结合CCL17的抗体，编码抗体或片段的多核苷酸，以及制备和使用上述物质的方法。
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Patent Agency Ranking
4.发明授权Immunoglobulin cleavage fragments and disease indicators and compositions for detecting and binding such 有权免疫球蛋白切割片段和用于检测和结合的疾病指示剂和组合物公开(公告)号：US09481734B2
公开(公告)日：2016-11-01
申请号：US13804357
申请日：2013-03-14
Applicant: Janssen Biotech, Inc.
Inventor： Robert Jordan , David Knight , Randall Brezski , Mary Ryan , Diane Petrone
IPC: A61K39/40 , A61K39/395 , C07K16/42 , C07K16/06 , C07K16/28 , C07K16/36 , G01N33/68 , C07K7/08 , A61K39/00
CPC classification number: C07K16/42 , A61K2039/505 , A61K2039/507 , C07K7/08 , C07K16/065 , C07K16/2848 , C07K16/36 , C07K2317/24 , C07K2317/34 , C07K2317/50 , C07K2317/732 , C07K2317/734 , G01N33/6854 , G01N33/6857
Abstract: The invention relates to antibody compositions and use of the composition to detect disease processes associated with elaboration of proteases. The reagents are directed to assessing an IgG breakdown product that is the result of such proteolytic cleavage. The invention further relates to the use of a therapeutic immunospecific for IgG protease cleavage products to restore effector function to antibody compositions that are subject to protease cleavage.
Abstract translation: 本发明涉及抗体组合物和该组合物用于检测与精制蛋白酶相关的疾病过程的用途。 试剂用于评估作为这种蛋白水解切割结果的IgG分解产物。 本发明还涉及用于IgG蛋白酶切割产物的治疗免疫特异性用于恢复经受蛋白酶切割的抗体组合物的效应子功能的用途。
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公开(公告)号：US11414484B2
公开(公告)日：2022-08-16
申请号：US17060362
申请日：2020-10-01
Applicant: Janssen Biotech, Inc.
Inventor： Ken Boakye , Alfred Del Vecchio , John Kehoe , Eilyn Lacy , Lynne Murray , Mary Ryan , Sandra Santulli-Marotto , John Wheeler , Brian Whitaker , Alexey Teplyakov
Abstract: The present invention relates to antibodies specifically binding CCL17, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing.
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公开(公告)号：US08906649B2
公开(公告)日：2014-12-09
申请号：US13760663
申请日：2013-02-06
Applicant: Janssen Biotech, Inc.
Inventor： John Kehoe , Tatiana Ort , Kristen Picha , Mary Ryan , John Wheeler , Jennifer Lee Gardiner
CPC classification number: C07K16/18 , A61K2039/505 , C07K2317/21 , C07K2317/33 , C07K2317/55 , C07K2317/92
Abstract: The present invention relates to antibodies against human collagen II, polypeptides and polynucleotides encoding human collagen II antibodies or fragments thereof, and methods of making and using the foregoing.
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公开(公告)号：US20140220634A1
公开(公告)日：2014-08-07
申请号：US13760663
申请日：2013-02-06
Applicant: JANSSEN BIOTECH, INC.
Inventor： John Kehoe , Tatiana Ort , Kristen Picha , Mary Ryan , John Wheeler , Jennifer Lee Gardiner
IPC: C07K16/18
CPC classification number: C07K16/18 , A61K2039/505 , C07K2317/21 , C07K2317/33 , C07K2317/55 , C07K2317/92
Abstract: The present invention relates to antibodies against human collagen II, polypeptides and polynucleotides encoding human collagen II antibodies or fragments thereof, and methods of making and using the foregoing.
Abstract translation: 本发明涉及针对人胶原II的抗体，编码人胶原II抗体或其片段的多肽和多核苷酸，以及制备和使用上述物质的方法。
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8.发明申请Immunoglobulin Cleavage Fragments and Disease Indicators and Compositions for Detecting and Binding Such 审中-公开免疫球蛋白切割片段和疾病指示剂和组合物用于检测和结合公开(公告)号：US20130239238A1
公开(公告)日：2013-09-12
申请号：US13804357
申请日：2013-03-14
Applicant: JANSSEN BIOTECH, INC.
Inventor： Robert Jordan , David Knight , Randall Brezski , Mary Ryan , Diane Petrone
CPC classification number: C07K16/42 , A61K2039/505 , A61K2039/507 , C07K7/08 , C07K16/065 , C07K16/2848 , C07K16/36 , C07K2317/24 , C07K2317/34 , C07K2317/50 , C07K2317/732 , C07K2317/734 , G01N33/6854 , G01N33/6857
Abstract: The invention relates to antibody compositions and use of the composition to detect disease processes associated with elaboration of proteases. The reagents are directed to assessing an IgG breakdown product that is the result of such proteolytic cleavage. The invention further relates to the use of a therapeutic immunospecific for IgG protease cleavage products to restore effector function to antibody compositions that are subject to protease cleavage.
Abstract translation: 本发明涉及抗体组合物和该组合物用于检测与精制蛋白酶相关的疾病过程的用途。 试剂用于评估作为这种蛋白水解切割结果的IgG分解产物。 本发明还涉及用于IgG蛋白酶切割产物的治疗免疫特异性用于恢复经受蛋白酶切割的抗体组合物的效应子功能的用途。
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