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公开(公告)号：US20170234883A1
公开(公告)日：2017-08-17
申请号：US15415379
申请日：2017-01-25
Applicant: Genentech, Inc.
Inventor： Mark S. DENNIS , Bonnee RUBINFELD , Paul POLAKIS , Aya JAKOBOVITS
IPC: G01N33/574 , C07K16/40
CPC classification number: G01N33/57434 , A61K38/05 , A61K39/39558 , A61K45/06 , A61K47/6851 , A61K47/6869 , A61K47/6871 , A61K49/0002 , A61K49/0058 , A61K51/1045 , A61K51/1072 , A61K2039/505 , C07K16/30 , C07K16/3069 , C07K16/40 , C07K17/00 , C07K2317/24 , C07K2317/31 , C07K2317/515 , C07K2317/54 , C07K2317/55 , C07K2317/565 , C07K2317/567 , C07K2317/622 , C07K2317/92
Abstract: Anti-STEAP-1 antibodies and immunoconjugates thereof are provided. Methods of using anti-STEAP-1 antibodies and immunoconjugates thereof are provided.
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Patent Agency Ranking
公开(公告)号：US20150166674A1
公开(公告)日：2015-06-18
申请号：US14517682
申请日：2014-10-17
Applicant: GENENTECH, INC.
Inventor： Mark S. DENNIS , Bonnee RUBINFELD , Paul POLAKIS , Aya JAKOBOVITS
IPC: C07K16/40 , A61K38/05 , A61K47/48 , A61K45/06 , A61K39/395
CPC classification number: G01N33/57434 , A61K38/05 , A61K39/39558 , A61K45/06 , A61K47/6851 , A61K47/6869 , A61K47/6871 , A61K49/0002 , A61K49/0058 , A61K51/1045 , A61K51/1072 , A61K2039/505 , C07K16/30 , C07K16/3069 , C07K16/40 , C07K17/00 , C07K2317/24 , C07K2317/31 , C07K2317/515 , C07K2317/54 , C07K2317/55 , C07K2317/565 , C07K2317/567 , C07K2317/622 , C07K2317/92
Abstract: Anti-STEAP-1 antibodies and immunoconjugates thereof are provided. Methods of using anti-STEAP-1 antibodies and immunoconjugates thereof are provided.
Abstract translation: 提供抗STEAP-1抗体及其免疫偶联物。 提供了使用抗STEAP-1抗体及其免疫偶联物的方法。
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公开(公告)号：US20160274116A1
公开(公告)日：2016-09-22
申请号：US14919388
申请日：2015-10-21
Applicant: Genentech, Inc.
Inventor： Siminder ATWAL , Jo-Anne HONGO , Mark LACKNER , Elizabeth PUNNOOSE , Bonnee RUBINFELD , Rajesh VIJ
IPC: G01N33/574
CPC classification number: G01N33/57434 , C07K16/3069 , C12N5/0693 , C12Y116/01 , C12Y301/03048 , G01N33/57492 , G01N2333/4742 , G01N2333/70596 , G01N2333/90287 , G01N2333/916 , G01N2800/52
Abstract: The invention provides methods for diagnosing prostate cancer. The invention also provides novel anti-STEAP-1 antibodies and uses thereof.
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公开(公告)号：US20160168261A1
公开(公告)日：2016-06-16
申请号：US14953763
申请日：2015-11-30
Applicant: Genentech, Inc.
Inventor： Mark DENNIS , Jan MARIK , Paul POLAKIS , Bonnee RUBINFELD , Simon WILLIAMS
CPC classification number: C07K16/40 , A61K47/6811 , A61K47/6871 , A61K51/1072 , A61K51/1075 , A61K51/1093 , A61K51/1096 , A61K2039/505 , C07B59/008 , C07B2200/05 , C07K16/3069 , C07K2317/24 , C07K2317/565 , C07K2317/92 , G01N33/534 , G01N33/57492 , G01N33/60 , G01N33/6893
Abstract: Anti-STEAP-1 antibodies and immunoconjugates thereof are provided. Methods of using anti-STEAP-1 antibodies and immunoconjugates thereof are provided. Methods of detecting or determining the presence of STEAP-1 proteins are provided.
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5.发明申请公开(公告)号：US20170349639A1
公开(公告)日：2017-12-07
申请号：US15385528
申请日：2016-12-20
Applicant: Genentech, Inc.
Inventor： James A. ERNST , Paul POLAKIS , Bonnee RUBINFELD , Venita I. DEALMEIDA
CPC classification number: C07K14/4702 , A61K38/00 , C07K14/71 , G01N2333/71 , Y02A50/473
Abstract: The present invention provides for chimeric Wnt antagonists comprising a Frz domain component derived from a Frizzled protein, a secreted Frizzled related protein or Ror protein and an Fc immunoglobulin component, and their use in the treatment and diagnostic detection of cellular Wnt signaling and Wnt-mediated disorders, including cancer.
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公开(公告)号：US20170121424A1
公开(公告)日：2017-05-04
申请号：US15289485
申请日：2016-10-10
Applicant: Genentech, Inc.
Inventor： Mark DENNIS , Jan MARIK , Paul POLAKIS , Bonnee RUBINFELD , Simon WILLIAMS
IPC: C07K16/40 , C07B59/00 , G01N33/574 , G01N33/534 , G01N33/60 , A61K51/10 , C07K16/30
CPC classification number: C07K16/40 , A61K47/6811 , A61K47/6871 , A61K51/1072 , A61K51/1075 , A61K51/1093 , A61K51/1096 , A61K2039/505 , C07B59/008 , C07B2200/05 , C07K16/3069 , C07K2317/24 , C07K2317/565 , C07K2317/92 , G01N33/534 , G01N33/57492 , G01N33/60 , G01N33/6893
Abstract: Anti-STEAP-1 antibodies and immunoconjugates thereof are provided. Methods of using anti-STEAP-1 antibodies and immunoconjugates thereof are provided. Methods of detecting or determining the presence of STEAP-1 proteins are provided.
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